Wnt3a Inhibitor Attenuates Remifentanil-Induced Hyperalgesia via Downregulating Spinal NMDA Receptor in Rats.

abstract：:Osteoarthritis (OA) is the most prevalent arthritis worldwide and is characterized by chronic pain and impaired physical function. We hypothesized that heightened pain in hand OA could be reduced with duloxetine or pregabalin. In this prospective, randomized clinical study, we recruited 65 participants, aged 40-75 yea...

journal_title：Journal of pain research

authors： Sofat N,Harrison A,Russell MD,Ayis S,Kiely PD,Baker EH,Barrick TR,Howe FA

更新日期：2017-10-10 00:00:00

abstract：Background:Thoracoscopic surgery (TS) has been performed as a minimally invasive procedure since the beginning of the 1990s. This has led to a dramatic change in the postoperative condition of these patients, facilitating early ambulation and easier management of postoperative pain. However, empirical evidence on posto...

journal_title：Journal of pain research

authors： Kuroda H,Mizuno H,Dejima H,Watanabe K,Yoshida T,Naito Y,Sakao Y

更新日期：2017-11-15 00:00:00

abstract：PURPOSE:Conditioned pain modulation (CPM) is an experimental approach for probing endogenous analgesia by which one painful stimulus (the conditioning stimulus) may inhibit the perceived pain of a subsequent stimulus (the test stimulus). Animal studies suggest that CPM is mediated by a spino-bulbo-spinal loop using obj...

journal_title：Journal of pain research

authors： Bernaba M,Johnson KA,Kong JT,Mackey S

更新日期：2014-11-26 00:00:00

abstract：Purpose:The aim of this prospective study was to assess the behavior of emergency department (ED) nurses with regard to pain and their role in pain management in a real-life clinical setting. Methods:A total of 509 consecutive patients were enrolled during a 6-week period. A case-report form was used to collect data o...

journal_title：Journal of pain research

authors： Sardo S,Galletta M,Coni E,Aviles Gonzalez CI,Piras I,Pia G,Evangelista M,Musu M,Finco G

更新日期：2020-09-22 00:00:00

abstract：Purpose:Dysmenorrhea is a common disorder that substantially disrupts the lives of young women. The frequency of 14 associated symptoms both within and outside the pelvis was determined. Patients and methods:Symptom questionnaires were completed by 168 women with dysmenorrhea, allocated to three groups based on their ...

journal_title：Journal of pain research

authors： Evans SF,Brooks TA,Esterman AJ,Hull ML,Rolan PE

更新日期：2018-12-13 00:00:00

abstract：:Purpose: The study aimed to evaluate the analgesic efficiency of dexmedetomidine (DEX) when added to levobupivacaine in continuous ultrasound-guided serratus anterior plane block (SAPB) performed at the end of major thoracic surgery. Methods: This randomized, double-blind trial included 50 adults undergoing thoracic s...

journal_title：Journal of pain research

authors： Abdallah NM,Bakeer AH,Youssef RB,Zaki HV,Abbas DN

更新日期：2019-04-30 00:00:00

abstract：Background:The objective of this study was to compare the clinical and radiological outcomes between patients with or without axial symptoms (AS) and investigate the risk factors associated with AS by multivariate regression analysis in anterior cervical discectomy and fusion (ACDF). Materials and methods:The records ...

journal_title：Journal of pain research

authors： Zhou J,Li L,Li T,Xue Y

更新日期：2018-10-26 00:00:00

abstract：Purpose:Premonitory symptoms (PSs) of migraine are those that precede pain in a migraine attack. Previous studies suggest that treatment during this phase may prevent the onset of pain; however, this approach requires that patients be able to recognize their PSs. Our objectives were to evaluate patients' actual ability...

journal_title：Journal of pain research

authors： Gago-Veiga AB,Pagán J,Henares K,Heredia P,González-García N,De Orbe MI,Ayala JL,Sobrado M,Vivancos J

更新日期：2018-09-27 00:00:00

abstract：Background:Many aspects of study conduct impact the observed effect size of treatment. Data were utilized from a recently published meta-analysis of randomized, double-blind, placebo-controlled, clinical trials performed for the United States Food and Drug Administration (FDA) approval of full mu-agonist opioids for th...

journal_title：Journal of pain research

authors： Meske DS,Vaughn BJ,Kopecky EA,Katz N

更新日期：2019-11-20 00:00:00

abstract：:Pain is highly prevalent, but frequently untreated or under-treated, and health care professionals are faced with a range of treatment challenges. Multimodal therapy is recommended and can be achieved using open combinations (ie, concomitant administration) of individual agents, fixed-dose combinations (FDCs), or mult...

journal_title：Journal of pain research

authors： Almansa C,Frampton CS,Vela JM,Whitelock S,Plata-Salamán CR

更新日期：2019-09-04 00:00:00

abstract：:Pulsed radiofrequency is an effective, safe, and nondestructive pain treatment technique that has been insufficiently reported in the treatment of supraorbital neuralgia. We report the successful use of pulsed radiofrequency to alleviate acute severe supraorbital neuralgia in a post-craniotomy patient. A 52-year-old f...

journal_title：Journal of pain research

authors： Xiao X,Ren H,Ji N,Luo F

更新日期：2018-08-08 00:00:00

abstract：:[This corrects the article DOI: 10.2147/JPR.S203721.]. ...

journal_title：Journal of pain research

authors：

更新日期：2020-08-26 00:00:00

abstract：:Pain is the most common reason people visit emergency rooms. Pain does not discriminate on the basis of gender, race or age. The state of pain management in the emergency department (ED) is disturbing. ED physicians often do not provide adequate analgesia to their patients, do not meet patients' expectations in treati...

journal_title：Journal of pain research

authors： Motov SM,Khan AN

更新日期：2008-12-09 00:00:00

abstract：Purpose:The aim of this study was to evaluate postoperative discomfort in patients undergoing ambulatory strabismus under general anesthesia, and to identify risk factors associated with the discomfort. Patients and Methods:A cross-sectional study was conducted among 210 consecutive patients undergoing ambulatory stra...

journal_title：Journal of pain research

authors： Huang J,Lin J,Xiong Y,Wang Z,Zhu Y,Ye H,Guo W

更新日期：2020-05-05 00:00:00

abstract：Purpose:No final conclusion has yet been reached on characteristics of postoperative pain and pain-related factors after video-assisted thoracoscopic surgery (VATS). This study was designed to explore features of acute severe pain and chronic post-surgical pain (CPSP), and the pain-related factors of VATS. Patients an...

journal_title：Journal of pain research

authors： Tong Y,Wei P,Wang S,Sun Q,Cui Y,Ning N,Chen S,He X

更新日期：2020-07-21 00:00:00

abstract：Background:While the concomitant administration of painful and rewarding stimuli tends to reduce the perception of one another, recent evidence shows that pleasant pain relief is experience after the interruption of noxious stimuli. On neurobiological grounds, these opponent processes should translate into decreased ac...

journal_title：Journal of pain research

authors： Bitar N,Dugré JR,Marchand S,Potvin S

更新日期：2020-06-08 00:00:00

abstract：Background:Millions of people worldwide are suffering from pain. Non-pharmacological therapy has an important role in the treatment of pain and is recognized as a valuable, simple help to lower the dosage of analgesic drugs needed, decreasing the side effects, reducing drug dependency and reducing health care costs; ho...

journal_title：Journal of pain research

authors： Jira L,Weyessa N,Mulatu S,Alemayehu A

更新日期：2020-11-16 00:00:00

abstract：Purpose:To examine the trends of analgesic prescribing at public tertiary hospital outpatient settings and explore the patterns of their utilization in nonsteroidal anti-inflammatory drugs (NSAIDs), tramadol, and opioid patients. Patients and methods:This cross-sectional study was conducted from 2010 to 2016 using the...

journal_title：Journal of pain research

authors： Zin CS,Nazar NI,Rahman NS,Alias NE,Ahmad WR,Rani NS,Cardosa MS,Ng KS,Ye FL

更新日期：2018-09-20 00:00:00

abstract：Objective:To demonstrate the importance of recognizing and separating nonmedian nerve-related symptoms from those related to median nerve compression at the carpal tunnel. Methods:The records of 80 patients, aged 31-82 years (39 males and 41 females), who had undergone median nerve decompression using open and endosco...

journal_title：Journal of pain research

authors： Lazaro RP,Eagan TS

更新日期：2017-10-24 00:00:00

abstract：:Multisite pain, or pain that occurs simultaneously at >1 anatomical site, is more prevalent than single-site pain. While multisite pain affects over half of older adults, it remains an understudied pain entity that may have important functional implications in an aging population. Greater understanding of this complex...

journal_title：Journal of pain research

authors： Butera KA,Roff SR,Buford TW,Cruz-Almeida Y

更新日期：2019-03-29 00:00:00

abstract：OBJECTIVE:Patients with chronic fatigue syndrome (CFS) complain of long-lasting fatigue and pain which are not relieved by rest and worsened by physical exertion. Previous research has implicated metaboreceptors of muscles to play an important role for chronic fatigue and pain. Therefore, we hypothesized that blocking ...

journal_title：Journal of pain research

authors： Staud R,Kizer T,Robinson ME

更新日期：2017-06-26 00:00:00

abstract：:Osteoarthritis (OA) is a common degenerative disease that affects the vast majority of the elderly and may eventually embark on the road of the total knee arthroplasty (TKA), although controversy still exists in the medical community about the best therapies for osteoarthritis. Compared with physical therapy, oral ana...

journal_title：Journal of pain research

authors： Zhang Y,Chen X,Tong Y,Luo J,Bi Q

更新日期：2020-08-04 00:00:00

abstract：Background:Femoral nerve block (FNB) has been considered as an excellent analgesic modality in total knee arthroplasty (TKA) pain control. However, relatively high concentration of ropivacaine could lead to quadriceps muscle weakness and increase the risk of postoperative falls. Objective:This double-blinded randomize...

journal_title：Journal of pain research

authors： Yang X,Kang W,Xiong W,Lu D,Zhou Z,Chen X,Zhou X,Feng X

更新日期：2019-12-17 00:00:00

abstract：Background:The ability to accurately diagnose and objectively localize pain generators in chronic pain sufferers remains a major clinical challenge since assessment relies on subjective patient complaints and relatively non-specific diagnostic tools. Developments in clinical molecular imaging, including advances in ima...

journal_title：Journal of pain research

authors： Cipriano PW,Lee SW,Yoon D,Shen B,Tawfik VL,Curtin CM,Dragoo JL,James ML,McCurdy CR,Chin FT,Biswal S

更新日期：2018-10-12 00:00:00

abstract：Purpose:Post-herpetic neuralgia (PHN) is a common herpes zoster (HZ) complication, where pain persists 90 days after the initial HZ diagnosis. Evaluating PHN risk is essential for determining the burden on patients and health-care systems, but research shows variable estimates. The extent to which these differences are...

journal_title：Journal of pain research

authors： Tanenbaum HC,Lawless A,Sy LS,Hong V,Ackerson B,Bruxvoort K,Luo Y,Tseng HF

更新日期：2020-07-13 00:00:00

abstract：Purpose:This study aimed to review and pool the current literature on intra-articular ozone injection in knee osteoarthritis (OA) patients. Methods:A systematic review of three big databases was performed to identify all English-language randomized clinical trials (RCTs) that evaluated the efficacy of intra-articular ...

journal_title：Journal of pain research

authors： Raeissadat SA,Tabibian E,Rayegani SM,Rahimi-Dehgolan S,Babaei-Ghazani A

更新日期：2018-10-25 00:00:00

abstract：:Recently, attention to the lifestyle of patients has been rapidly increasing in the field of pain therapy, particularly with regard to the role of nutrition in pain development and its management. In this review, we summarize the latest findings on the role of nutrition and nutraceuticals, microbiome, obesity, soy, om...

journal_title：Journal of pain research

authors： De Gregori M,Muscoli C,Schatman ME,Stallone T,Intelligente F,Rondanelli M,Franceschi F,Arranz LI,Lorente-Cebrián S,Salamone M,Ilari S,Belfer I,Allegri M

更新日期：2016-12-08 00:00:00

abstract：:Cervical intervertebral disc has long been considered a common source of neck pain. However, the pain caused by the disc itself has not been clearly defined so far, and its diagnosis and treatment has always been controversial. Degenerative cervical disc has a rich supply of nerve fibers, is prone to inflammatory reac...

journal_title：Journal of pain research

authors： Peng B,DePalma MJ

更新日期：2018-11-14 00:00:00

abstract：Background:Pain is a common and undertreated non-motor symptom in patients with Parkinson's disease (PD). Opioids have been seldom used in PD because they could worsen cognitive and motor functions. Objective:We aimed to assess efficacy and tolerability of tapentadol in PD patients. Methods:We retrospectively reviewe...

journal_title：Journal of pain research

authors： Freo U,Furnari M,Ori C

更新日期：2018-09-13 00:00:00

abstract：:Paced breathing has shown efficacy in fibromyalgia (FM), but the mechanisms associated with symptom change are largely unknown. We investigated whether changes in respiratory rate (RR) alone resulted in autonomic changes during normal, paced, and mechanically assisted breathing in untrained FM patients and controls. P...

journal_title：Journal of pain research

authors： Schmidt JE,O'Brien TG,Hooten WM,Joyner MJ,Johnson BD

更新日期：2017-12-08 00:00:00