Abstract:
:Cervical intervertebral disc has long been considered a common source of neck pain. However, the pain caused by the disc itself has not been clearly defined so far, and its diagnosis and treatment has always been controversial. Degenerative cervical disc has a rich supply of nerve fibers, is prone to inflammatory reactions, and is susceptible to pain that can be provoked by disc stimulation or distention, and can be eliminated by block. Overwhelming clinical evidence demonstrates that neck pain in patients with degenerative cervical radiculopathy or myelopathy can be subsided rapidly by anterior cervical surgery, further indicating that this neck pain stems from the pathology of cervical disc itself. Cervical discography is advocated as the only test that connects disease to symptoms, but the procedure remains controversial. If strict criteria and technique are maintained, discography can discriminate painful, symptomatic discs from nonpainful, asymptomatic discs. Discogenic neck pain alone without cervical disc herniation or cervical spondylosis accounts for a large proportion of chronic neck pain. For these patients who continue to have refractory neck pain and fail to respond to conservative treatment, anterior cervical fusion surgery or artificial cervical disc replacement may be a better choice, and preoperative cervical discography can guarantee the excellent surgical results. Existing basic and clinical studies have scientifically shown that cervical intervertebral disc degeneration can lead to neck pain.
journal_name
J Pain Resjournal_title
Journal of pain researchauthors
Peng B,DePalma MJdoi
10.2147/JPR.S180018subject
Has Abstractpub_date
2018-11-14 00:00:00pages
2853-2857issn
1178-7090pii
jpr-11-2853journal_volume
11pub_type
杂志文章abstract:Background:Suspecting carpal tunnel syndrome (CTS) in patients with hand pain is usual. Considering the variable rate of false-negative results in nerve conduction study (NCS), as a frequent reference confirmatory standard test, we aimed to evaluate the diagnostic accuracy of neuromuscular ultrasound in patients with c...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S164004
更新日期:2018-07-10 00:00:00
abstract::This paper reviews the current clinical data for the role of transdermal buprenorphine (BUP TDS) in the treatment of diverse acute and chronic pain syndromes. Literature searches were carried out using PubMed (1988 to June 2009). The published findings seem to support hypotheses regarding the rather unique analgesic m...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/jpr.s6503
更新日期:2009-09-15 00:00:00
abstract::Purpose: Although amiodarone is classified as a Vaughan-Williams class Ⅲ antiarrhythmic drug, it has inhibitory effects on voltage-gated sodium and calcium channels and on β-adrenergic receptors. Given these pharmacological profiles, amiodarone may have analgesic properties. Most patients who are prescribed amiodarone...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S196480
更新日期:2019-06-06 00:00:00
abstract:BACKGROUND:Low back pain is often called nonspecific pain. In this type of low back pain, various emotions and stress are known to strongly affect pain perception. The purpose of this study is to investigate how the degree of low back pain changes in people with chronic mild low back pain when they are inside and outsi...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S36960
更新日期:2012-01-01 00:00:00
abstract::Livedoid vasculopathy (LV) is a chronic prothrombotic disease of cutaneous micro-circulation resulting in cutaneous ischemia and infarction. As a rare disease, LV has an estimated incidence of ten cases per million. Not only correct diagnosis but also effective treatments are very difficult for patients with LV. Due t...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S133462
更新日期:2017-03-17 00:00:00
abstract:BACKGROUND:Detecting the efficacy of novel analgesic agents in neuropathic pain is challenging. There is a critical need for study designs with the desirable characteristics of assay sensitivity, low placebo response, reliable pain recordings, low cost, short duration of exposure to test drug and placebo, and relevant ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S34098
更新日期:2012-01-01 00:00:00
abstract::The observation of pain in others may enhance or reduce self-pain, yet the boundary conditions and factors that determine the direction of such effects are poorly understood. The current study set out to show that visual stimulus awareness plays a crucial role in determining whether vicarious pain primarily activates ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S132744
更新日期:2017-07-31 00:00:00
abstract::Purpose: The study aimed to evaluate the analgesic efficiency of dexmedetomidine (DEX) when added to levobupivacaine in continuous ultrasound-guided serratus anterior plane block (SAPB) performed at the end of major thoracic surgery. Methods: This randomized, double-blind trial included 50 adults undergoing thoracic s...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S195431
更新日期:2019-04-30 00:00:00
abstract::This open-label, phase 3b study (ClinicalTrials.gov Identifier: NCT00983073) evaluated the effectiveness, and tolerability of tapentadol for severe, chronic osteoarthritis knee pain that was inadequately managed with World Health Organization (WHO) Step I or II analgesics or co-analgesics, or that was not treated with...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S30540
更新日期:2012-01-01 00:00:00
abstract::Phantom-limb pain (PLP) belongs among difficult-to-treat chronic pain syndromes. Treatment options for PLP are to a large degree implicated by the level of understanding the mechanisms and nature of PLP. Research and clinical findings acknowledge the neuropathic nature of PLP and also suggest that both peripheral as w...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S16733
更新日期:2012-01-01 00:00:00
abstract:Background:With the increase in life expectancy seen throughout the world, the prevalence of degenerative spinal pathology and surgery to treat it has increased. Spinal surgery under general anesthesia leads to various problems and complications, especially in patients with numerous medical comorbidities or elderly pat...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S227212
更新日期:2020-01-21 00:00:00
abstract:Purpose:To identify risk factors for pain after transarterial chemoembolization with drug-eluting beads (DEB-TACE) for hepatocellular carcinoma (HCC). Patients and Methods:In this retrospective study, a total of 118 consecutive patients who underwent DEB-TACE between June 2016 and May 2019 with post-TACE pain were inc...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S246197
更新日期:2020-03-27 00:00:00
abstract:INTRODUCTION:Although the majority of opioids in the US are prescribed by nonpain specialists, these providers often report inadequate training in chronic pain management and opioid prescribing. The extent of health care providers' knowledge of opioid prescribing for chronic pain has not been well established. The purp...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S98273
更新日期:2016-03-10 00:00:00
abstract::Different pericardial catheters have been suggested as an effective alternative method for drainage of pericardial effusion. The aim of this study was to determine the performance, pain, and quality of life on use of central venous catheter (CVC) for drainage of pericardial effusion in patients undergoing open heart s...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S116483
更新日期:2016-10-31 00:00:00
abstract:Background:Postherpetic neuralgia (PHN) refers to pain which remains after the healing of rashes from herpes zoster. Previous literatures have shown that acupuncture has potential benefits for PHN, but evidence remains lacking. Thus, we have performed a systematic review and meta-analysis to identify the effectiveness ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S199950
更新日期:2019-07-16 00:00:00
abstract::Osteoarthritis (OA) is the most prevalent arthritis worldwide and is characterized by chronic pain and impaired physical function. We hypothesized that heightened pain in hand OA could be reduced with duloxetine or pregabalin. In this prospective, randomized clinical study, we recruited 65 participants, aged 40-75 yea...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S147640
更新日期:2017-10-10 00:00:00
abstract:BACKGROUND:Opioids and other controlled substances prescribed for chronic pain are associated with abuse, addiction, and death, prompting national initiatives to identify safe and effective pain management strategies including topical analgesics. METHODS:This prospective, observational study evaluated changes from bas...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S143513
更新日期:2017-10-03 00:00:00
abstract:Background:Erector spinae plane block (ESPB) as a new trunk fascia block technique was proposed in 2016. ESPB has aroused the interest of many nerve block experts. However, there are few clinical studies on ESPB for lumbar surgery, and its effectiveness and safety are controversial. The goal of this review is to summar...
journal_title:Journal of pain research
pub_type: 杂志文章,评审
doi:10.2147/JPR.S256205
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the analgesic effectiveness of intra-articular botulinum toxin Type B (BoNT/B) in a murine model of chronic degenerative arthritis pain. METHODS AND MATERIALS:Chronic arthritis was produced in adult C57Bl6 mice by intra-articular injection of Type IV collagenase into the left knee. Following indu...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S12520
更新日期:2010-09-06 00:00:00
abstract::Purpose: One of the main factor of cervical foraminal stenosis (CFS) is the hypertrophic change of the cervical facet joint. In order to analyze the connection between CFS and the facet joint hypertrophy, we devised a new morphological parameter, called the cervical facet joint cross-sectional area (CFJA). The CFJA ha...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S204567
更新日期:2019-04-24 00:00:00
abstract:Purpose:Although the use of opioids is increasing in South Korea, there have been no studies on the serious complications caused by the opioids. The aim of this study was to investigate the rare but serious complications through medicolegal analysis. Materials and Methods:From January 1994 to December 2019, we retrosp...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S256759
更新日期:2020-06-25 00:00:00
abstract::Pain is considered a multidimensional conscious experience that includes a sensory component and a negative affective-motivational component. The negative affective-motivational component of pain is different from the sensory component and amplifies the pain experience. Nowadays, a significant number of preclinical re...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S139679
更新日期:2017-11-06 00:00:00
abstract::Neuromuscular blockade is a desirable or even essential component of general anesthesia for major surgical operations. As the population continues to age, and more operations are conducted in the elderly, due consideration must be given to neuromuscular blockade in these patients to avoid possible complications. This ...
journal_title:Journal of pain research
pub_type: 杂志文章,评审
doi:10.2147/JPR.S85183
更新日期:2016-06-17 00:00:00
abstract:BACKGROUND:No proof of efficacy, in the form of a randomized controlled trial (RCT), exists to support pulsed radiofrequency (PRF) treatment of the dorsal root ganglion (DRG) for chronic lumbar radicular (CLR) pain. We determined the feasibility of a larger trial (primary objective), and also explored the efficacy of P...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S55749
更新日期:2014-01-10 00:00:00
abstract:Purpose:The quadratus lumborum block (QLB) is a relatively new regional analgesic technique that could provide analgesia to the abdominal wall and reduce postoperative opioid consumption. We investigated the opioid-sparing effect of a unilateral lateral QLB in laparoscopic nephrectomy. Patients and Methods:A total of ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S257466
更新日期:2020-07-03 00:00:00
abstract:INTRODUCTION:Heat/capsaicin skin sensitization is a well-characterized human experimental model to induce hyperalgesia and allodynia. Using this model, gabapentin, among other drugs, was shown to significantly reduce cutaneous hyperalgesia compared to placebo. Since the larger thermal probes used in the original studie...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S53437
更新日期:2013-11-07 00:00:00
abstract:Background:It is becoming increasingly important to understand the mechanisms of spinal cord stimulation (SCS) in alleviating neuropathic pain as novel stimulation paradigms arise. Purpose:Additionally, the small anatomic scale of current SCS animal models is a barrier to more translational research. Methods:Using ch...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S139843
更新日期:2018-06-15 00:00:00
abstract:Purpose:Despite the rise in opioid-related hospitalizations, there has been little research regarding opioid-related healthcare utilization. The objective of this study was to estimate the mean adjusted hospital costs, payments, and length of stay (LOS) for opioid-related visits for the nation and each of the nine US c...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S184724
更新日期:2018-12-04 00:00:00
abstract:Objective:To report a rare case of spontaneous fusion (SF) following cervical disc arthroplasty (CDA), to review the related literature, and to propose a new measure to prevent it. Methods:The course of a patient with SF is described here. The potential causes, risk factors, and preventive measure of SF after CDA publ...
journal_title:Journal of pain research
pub_type:
doi:10.2147/JPR.S242646
更新日期:2020-04-21 00:00:00
abstract:Background:Cast immobilization is the primary treatment for children with forearm fractures. After emergency department (ED) discharge, some patients develop cast-related pain (CstRP) around the distal part of the upper extremity. We examined variables associated with ED revisits due to CstRP in children with forearm f...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S226447
更新日期:2020-01-08 00:00:00