Analgesic effects of amiodarone in mouse models of pain.

abstract：INTRODUCTION:Although the majority of opioids in the US are prescribed by nonpain specialists, these providers often report inadequate training in chronic pain management and opioid prescribing. The extent of health care providers' knowledge of opioid prescribing for chronic pain has not been well established. The purp...

journal_title：Journal of pain research

authors： Pearson AC,Eldrige JS,Moeschler SM,Hooten WM

更新日期：2016-03-10 00:00:00

abstract：BACKGROUND:Opioids are the most important pharmacological treatment for moderate-to-severe cancer pain, but side effects limit their use. Transdermal fentanyl (TDF) and oral prolonged-release oxycodone-naloxone (OXN-PR) are effective in controlling chronic pain, with less constipation compared to other opioids. However...

journal_title：Journal of pain research

authors： Roberto A,Greco MT,Legramandi L,Galli F,Galli M,Corli O

更新日期：2017-09-04 00:00:00

abstract：Introduction:Cannabidiol (CBD) is reported to produce pain relief, but the clinically relevant cellular and molecular mechanisms remain uncertain. The TRPV1 receptor integrates noxious stimuli and plays a key role in pain signaling. Hence, we conducted in vitro studies, to elucidate the efficacy and mechanisms of CBD f...

journal_title：Journal of pain research

authors： Anand U,Jones B,Korchev Y,Bloom SR,Pacchetti B,Anand P,Sodergren MH

更新日期：2020-09-11 00:00:00

abstract：:Rotator-cuff tears (RCTs) are typically associated with chronic pain. The most common treatment for reducing pain is the injection of cortisone into the injury site. An alternative and increasingly used technique is the injection of autologous platelet-rich plasma (PRP). A limitation of cortisone is its pain relief is...

journal_title：Journal of pain research

authors： Kuffler DP

更新日期：2018-10-09 00:00:00

abstract：:The objective of this study was to evaluate the relationship between magnetic resonance imaging (MRI) findings and previous low back pain (LBP) in participants without current LBP. Current LBP was defined as LBP during the past month. Previous LBP was defined as a history of medical consultation for LBP. Ninety-one pa...

journal_title：Journal of pain research

authors： Tonosu J,Oka H,Matsudaira K,Higashikawa A,Okazaki H,Tanaka S

更新日期：2016-12-29 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Major abdominal cancer surgeries are associated with significant perioperative mortality and morbidity due to myocardial ischemia and infarction. This study examined the effect of perioperative patient controlled epidural analgesia (PCEA) on occurrence of ischemic cardiac injury in ischemic pa...

journal_title：Journal of pain research

authors： Mohamad MF,Mohammad MA,Hetta DF,Ahmed EH,Obiedallah AA,Elzohry AAM

更新日期：2017-04-12 00:00:00

abstract：OBJECTIVE:Lymphocyte apoptosis in critical illness is associated with immunosuppression. We explored for the first time the associations between pain ratings and expression of the apoptotic receptor Fas on B and T cells in critically ill patients and the potential mediating effects of adrenocorticotropic hormone (ACTH)...

journal_title：Journal of pain research

authors： Papathanassoglou E,Mpouzika MD,Giannakopoulou M,Bozas E,Middleton N,Tsiaousis G,Karabinis A

更新日期：2017-01-13 00:00:00

abstract：:Adolescent low back pain (ALBP) is a common form of adolescent morbidity which remains poorly understood. When attempting a meta-analysis of observational studies into ALBP, in an effort to better understand associated risk factors, it is important that the studies involved are homogenic, particularly in terms of the ...

journal_title：Journal of pain research

authors： Milanese S,Grimmer-Somers K

更新日期：2010-05-17 00:00:00

abstract：Background:The objective of this study was to compare the clinical and radiological outcomes between patients with or without axial symptoms (AS) and investigate the risk factors associated with AS by multivariate regression analysis in anterior cervical discectomy and fusion (ACDF). Materials and methods:The records ...

journal_title：Journal of pain research

authors： Zhou J,Li L,Li T,Xue Y

更新日期：2018-10-26 00:00:00

abstract：Introduction:Sickle cell disease (SCD) is an inherited blood disorder characterized by abnormally shaped sickle cells. The hallmark of this disease is intermittent, painful vaso-occlusive episodes (VOE), but a subset of individuals with SCD experience chronic pain. The mechanism of transition to chronic pain is not wel...

journal_title：Journal of pain research

authors： Bakshi N,Lukombo I,Belfer I,Krishnamurti L

更新日期：2018-02-23 00:00:00

abstract：:Background: Chronic neuropathic pain (NP) is a complex disease that results from damage or presumed damage to the somatosensory nervous system. Current treatment regimens are often ineffective. The major impediment in developing effective treatments is our limited understanding of the underlying mechanisms. Preclinica...

journal_title：Journal of pain research

authors： Alshelh Z,Mills EP,Kosanovic D,Di Pietro F,Macey PM,Vickers ER,Henderson LA

更新日期：2019-08-02 00:00:00

abstract：:Osteoarthritis (OA) is the most prevalent arthritis worldwide and is characterized by chronic pain and impaired physical function. We hypothesized that heightened pain in hand OA could be reduced with duloxetine or pregabalin. In this prospective, randomized clinical study, we recruited 65 participants, aged 40-75 yea...

journal_title：Journal of pain research

authors： Sofat N,Harrison A,Russell MD,Ayis S,Kiely PD,Baker EH,Barrick TR,Howe FA

更新日期：2017-10-10 00:00:00

abstract：Purpose:Spinal cord stimulation (SCS) is a drug-free treatment for chronic neuropathic pain. Recent SCS technology can record evoked compound action potentials (ECAPs) in the spinal cord during therapy and utilize features of the sensed ECAP to optimize the SCS. The purpose of this work is to characterize the relevant ...

journal_title：Journal of pain research

authors： Chakravarthy K,Bink H,Dinsmoor D

更新日期：2020-12-04 00:00:00

abstract：:Topical treatments of localized neuropathic pain syndromes in general are mostly neglected, mainly due to the fact that most pain physicians expect that a topical formulation needs to result in a transdermal delivery of the active compounds. On the basis of the practical experience, this study brings forth a new, some...

journal_title：Journal of pain research

authors： Keppel Hesselink JM,Kopsky DJ,Sajben N

更新日期：2016-10-03 00:00:00

abstract：:Neuromuscular blockade is a desirable or even essential component of general anesthesia for major surgical operations. As the population continues to age, and more operations are conducted in the elderly, due consideration must be given to neuromuscular blockade in these patients to avoid possible complications. This ...

journal_title：Journal of pain research

authors： Lee LA,Athanassoglou V,Pandit JJ

更新日期：2016-06-17 00:00:00

abstract：Background:With the increase in life expectancy seen throughout the world, the prevalence of degenerative spinal pathology and surgery to treat it has increased. Spinal surgery under general anesthesia leads to various problems and complications, especially in patients with numerous medical comorbidities or elderly pat...

journal_title：Journal of pain research

authors： Kang SY,Kashlan ON,Singh R,Rane R,Adsul NM,Jung SC,Yi J,Cho HS,Kim HS,Jang IT,Oh SH

更新日期：2020-01-21 00:00:00

abstract：Background:Erector spinae plane block (ESPB) as a new trunk fascia block technique was proposed in 2016. ESPB has aroused the interest of many nerve block experts. However, there are few clinical studies on ESPB for lumbar surgery, and its effectiveness and safety are controversial. The goal of this review is to summar...

journal_title：Journal of pain research

authors： Qiu Y,Zhang TJ,Hua Z

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to assess the attitudes of maternal health care providers to pain relief during labor in Zaria, Nigeria. METHODS:This was a multicenter, collaborative, cross-sectional pilot study of provider perspectives concerning pain relief during labor. A structured, self-administered, que...

journal_title：Journal of pain research

authors： Ogboli-Nwasor E,Adaji S,Bature S,Shittu O

更新日期：2011-01-01 00:00:00

abstract：:Cancer and cancer treatment-related chronic pain affect a significant number of patients. The etiology of this pain is diverse and may include nociceptive and/or neuropathic characteristics. Treatment is often multifactorial and may require advanced interventional techniques, such as spinal cord stimulation (SCS). Thi...

journal_title：Journal of pain research

authors： Hagedorn JM,Pittelkow TP,Hunt CL,D'Souza RS,Lamer TJ

更新日期：2020-12-07 00:00:00

abstract：Background:Acupotomy, which involves the addition of a scalpel function to the conventional acupuncture treatment, has recently been applied as a conservative treatment method for lumbar disc herniation (LDH). This study investigated the effectiveness and safety of acupotomy, compared to manual acupuncture, for the tre...

journal_title：Journal of pain research

authors： Jeong JK,Kim E,Yoon KS,Jeon JH,Kim YI,Lee H,Kwon O,Jung SY,Lee JH,Yang C,Kang JH,Han CH

更新日期：2020-04-01 00:00:00

abstract：:Multisite pain, or pain that occurs simultaneously at >1 anatomical site, is more prevalent than single-site pain. While multisite pain affects over half of older adults, it remains an understudied pain entity that may have important functional implications in an aging population. Greater understanding of this complex...

journal_title：Journal of pain research

authors： Butera KA,Roff SR,Buford TW,Cruz-Almeida Y

更新日期：2019-03-29 00:00:00

abstract：Background:This study evaluates the reporting quality of randomized controlled trials (RCTs) on acupuncture use for the treatment of postherpetic neuralgia and explores related factors. Methods:The following six databases PubMed, Embase, Cochrane Library, VIP, CNKI, and SinoMed, were systematically searched from their...

journal_title：Journal of pain research

authors： Liu K,Zeng J,Pei W,Chen S,Luo Z,Lu L,Lin G

更新日期：2019-07-29 00:00:00

abstract：Background:Pain is a common and undertreated non-motor symptom in patients with Parkinson's disease (PD). Opioids have been seldom used in PD because they could worsen cognitive and motor functions. Objective:We aimed to assess efficacy and tolerability of tapentadol in PD patients. Methods:We retrospectively reviewe...

journal_title：Journal of pain research

authors： Freo U,Furnari M,Ori C

更新日期：2018-09-13 00:00:00

abstract：Purpose:The aim of this prospective study was to assess the behavior of emergency department (ED) nurses with regard to pain and their role in pain management in a real-life clinical setting. Methods:A total of 509 consecutive patients were enrolled during a 6-week period. A case-report form was used to collect data o...

journal_title：Journal of pain research

authors： Sardo S,Galletta M,Coni E,Aviles Gonzalez CI,Piras I,Pia G,Evangelista M,Musu M,Finco G

更新日期：2020-09-22 00:00:00

abstract：:Pain is highly prevalent, but frequently untreated or under-treated, and health care professionals are faced with a range of treatment challenges. Multimodal therapy is recommended and can be achieved using open combinations (ie, concomitant administration) of individual agents, fixed-dose combinations (FDCs), or mult...

journal_title：Journal of pain research

authors： Almansa C,Frampton CS,Vela JM,Whitelock S,Plata-Salamán CR

更新日期：2019-09-04 00:00:00

abstract：:Purpose: Thirty percent of patients with postherpetic neuralgia (PHN) receiving conservative treatment report unsatisfactory pain relief. Epidural steroid injections (ESIs) are commonly used as a therapeutic intervention in these patients. In this study, we aimed to determine if there are variables that predict the ef...

journal_title：Journal of pain research

authors： Ghanavatian S,Wie CS,Low RS,Butterfield RJ,Zhang N,Dhaliwal GS,Montoya JM,Swanson DL

更新日期：2019-04-23 00:00:00

abstract：:Recently, attention to the lifestyle of patients has been rapidly increasing in the field of pain therapy, particularly with regard to the role of nutrition in pain development and its management. In this review, we summarize the latest findings on the role of nutrition and nutraceuticals, microbiome, obesity, soy, om...

journal_title：Journal of pain research

authors： De Gregori M,Muscoli C,Schatman ME,Stallone T,Intelligente F,Rondanelli M,Franceschi F,Arranz LI,Lorente-Cebrián S,Salamone M,Ilari S,Belfer I,Allegri M

更新日期：2016-12-08 00:00:00

abstract：Background:The prevalence of neuropathic pain (NeP) has been estimated within specific health conditions; however, there are no published data on its broad prevalence in the US. The current exploratory study addresses this gap using the validated PainDetect questionnaire as a screener for probable NeP in a general-popu...

journal_title：Journal of pain research

authors： DiBonaventura MD,Sadosky A,Concialdi K,Hopps M,Kudel I,Parsons B,Cappelleri JC,Hlavacek P,Alexander AH,Stacey BR,Markman JD,Farrar JT

更新日期：2017-11-01 00:00:00

abstract：Background:Pancreatic cancer is a malignant disease with a high mortality rate and severe pain that is challenging to manage. To reduce the excruciating abdominal pain, opioids and adjuvant agents are conventionally used. Objectives:PRNCPB is a treatment of neural therapy. The number of studies assessing the effect on...

journal_title：Journal of pain research

authors： Molnár I,Hegyi G,Zsom L,Saahs C,Vagedes J,Kapócs G,Kovács Z,Sterner MG,Szőke H

更新日期：2019-01-14 00:00:00

abstract：Background:Chronic shoulder pain (CSP) is a common disease causing pain and functional limitation, which is highly prevalent and has substantial negative effects on the quality of life. Acupuncture has gained popularity and has been accepted gradually by many countries because it can successfully treat patients with ch...

journal_title：Journal of pain research

authors： Zhang S,Wang X,Yan CQ,Hu SQ,Huo JW,Wang ZY,Zhou P,Liu CH,Liu CZ

更新日期：2018-03-07 00:00:00