Abstract:
:Purpose: Thirty percent of patients with postherpetic neuralgia (PHN) receiving conservative treatment report unsatisfactory pain relief. Epidural steroid injections (ESIs) are commonly used as a therapeutic intervention in these patients. In this study, we aimed to determine if there are variables that predict the efficacy of ESI in patients with PHN. Patients and methods: We retrospectively identified patients seen at Mayo Clinic who had PHN and received ESI. From their medical records, we abstracted the demographic variables, concurrent medication use, anatomic approach and medication for ESI, and degree of pain relief at 2 and 12 weeks' postintervention. Results: None of the studied variables were significantly associated with efficacy of ESI in patients with PHN. PHN that began <11 months before treatment was predictive of a response to ESI at 12 weeks postintervention (positive predictive value, 55%). Patients who reported poor ESI efficacy 2 weeks after the intervention had a 94% chance of still having pain at 12 weeks. Conclusion: For this cohort of patients with PHN being treated with ESI, no demographic characteristics, concurrently used medications, or type of ESI were associated with ESI treatment efficacy at 2 or 12 weeks after the intervention.
journal_name
J Pain Resjournal_title
Journal of pain researchauthors
Ghanavatian S,Wie CS,Low RS,Butterfield RJ,Zhang N,Dhaliwal GS,Montoya JM,Swanson DLdoi
10.2147/JPR.S190646subject
Has Abstractpub_date
2019-04-23 00:00:00pages
1279-1286issn
1178-7090pii
190646journal_volume
12pub_type
杂志文章abstract:BACKGROUND:Cutaneous allodynia (CA) is a common feature of migraine, which has a complex underlying pathophysiology that is not well understood. In addition to pain, photophobia, phonophobia, osmophobia, nausea, and vomiting, CA can contribute to the overall disability caused by migraine. The presence of CA can be esta...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S103238
更新日期:2016-02-24 00:00:00
abstract:BACKGROUND:In Japan, there are limited options for switching opioid analgesics. Hydromorphone is an opioid analgesic that is routinely used instead of morphine for cancer pain; however, it is not yet available in Japan. The aim of this study was to assess the efficacy and safety of hydromorphone (DS-7113b) extended-rel...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S136937
更新日期:2017-08-18 00:00:00
abstract:OBJECTIVE:Patients with chronic fatigue syndrome (CFS) complain of long-lasting fatigue and pain which are not relieved by rest and worsened by physical exertion. Previous research has implicated metaboreceptors of muscles to play an important role for chronic fatigue and pain. Therefore, we hypothesized that blocking ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S139466
更新日期:2017-06-26 00:00:00
abstract:OBJECTIVE:To characterize the steady-state pharmacokinetic profile of hydromorphone extended-release (ER) in patients with chronic pain taking concomitant medications. METHODS:This open-label repeat-dose study enrolled 22 patients (mean age, 51.4 years; 81.8% female). All patients were receiving at least one concomita...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S33807
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Diagnosis of fibromyalgia (FM), a chronic musculoskeletal condition characterized by widespread pain and a constellation of symptoms, remains challenging and is often delayed. METHODS:Random forest modeling of electronic medical records was used to identify variables that may facilitate earlier FM identific...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/jpr.s8256
更新日期:2015-06-10 00:00:00
abstract:Purpose:Epidural analgesia provides safe and effective labor pain relief. However, labor episodic pain can occur during epidural analgesia, requiring epidural top-ups, and may result in decreased patient satisfaction. The primary aim of our study was to investigate the factors associated with labor episodic pain during...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S185073
更新日期:2019-02-15 00:00:00
abstract:Background:Postherpetic neuralgia (PHN) refers to pain which remains after the healing of rashes from herpes zoster. Previous literatures have shown that acupuncture has potential benefits for PHN, but evidence remains lacking. Thus, we have performed a systematic review and meta-analysis to identify the effectiveness ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S199950
更新日期:2019-07-16 00:00:00
abstract::Purpose: It has been reported that neck pain is more prevalent in episodic migraineurs (EM) than in the general population. Subjects with episodic migraine exhibited widespread hypersensitivity in cranio-cervical region. Our objectives were to explore the potential factors associated with the presence of neck pain for...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S200606
更新日期:2019-05-20 00:00:00
abstract:OBJECTIVES:To determine whether X-ray, computed tomography (CT), bone scan, and clinical impression accurately reflect the level of vertebral fracture in patients about to undergo vertebroplasty. DESIGN:Retrospective observational study, utilizing patient inpatient notes, referral correspondence, and clinicians' priva...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S32151
更新日期:2013-05-10 00:00:00
abstract:OBJECTIVE:This systematic review aimed to assess the efficacy, effectiveness, safety, and tolerability of osteopathic manipulative treatment (OMT) in patients with headache. BACKGROUND:Migraine is one of the most common and disabling medical conditions. It affects more than 15% of the general population, causing high ...
journal_title:Journal of pain research
pub_type: 杂志文章,评审
doi:10.2147/JPR.S130501
更新日期:2017-03-14 00:00:00
abstract:BACKGROUND:It has been demonstrated that N-ethyl-lidocaine (QX-314) can target the transient receptor protein vanilloid 1 (TRPV1) nociceptors when coadministered with capsaicin, resulting in a selective block of the nociceptors. Capsaicin is problematic in therapeutic use because it induces firing of nociceptors. The p...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S41614
更新日期:2013-01-01 00:00:00
abstract:Purpose:Although the use of opioids is increasing in South Korea, there have been no studies on the serious complications caused by the opioids. The aim of this study was to investigate the rare but serious complications through medicolegal analysis. Materials and Methods:From January 1994 to December 2019, we retrosp...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S256759
更新日期:2020-06-25 00:00:00
abstract:BACKGROUND:Sports-related injuries, such as sprains and strains, commonly occur during exercise and athletic events. Current therapy includes nonsteroidal anti-inflammatory drugs (NSAIDs), which have a high incidence of upper gastrointestinal side effects. The present study assessed the efficacy and safety of the diclo...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S15380
更新日期:2011-03-07 00:00:00
abstract:Purpose:Despite the rise in opioid-related hospitalizations, there has been little research regarding opioid-related healthcare utilization. The objective of this study was to estimate the mean adjusted hospital costs, payments, and length of stay (LOS) for opioid-related visits for the nation and each of the nine US c...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S184724
更新日期:2018-12-04 00:00:00
abstract:Background:Erector spinae plane block (ESPB) as a new trunk fascia block technique was proposed in 2016. ESPB has aroused the interest of many nerve block experts. However, there are few clinical studies on ESPB for lumbar surgery, and its effectiveness and safety are controversial. The goal of this review is to summar...
journal_title:Journal of pain research
pub_type: 杂志文章,评审
doi:10.2147/JPR.S256205
更新日期:2020-07-01 00:00:00
abstract:Background:The objective of this study was to compare the efficacy of calcitonin with diclofenac sodium in the treatment of patients with nonspecific low back pain (LBP) and type I Modic changes (MC1). Patients and methods:The study was a retrospective observational study with 109 patients who had nonspecific LBP and ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S158718
更新日期:2018-07-17 00:00:00
abstract:Background:Patients living with chronic upper limb and neck (ULN) pain are reliant on often ineffective therapies as they face limited options for effective long-term treatment. Objective:Prospective clinical studies have demonstrated that high-frequency spinal cord stimulation at 10 kHz (10 kHz SCS) is effective in t...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S257071
更新日期:2020-06-15 00:00:00
abstract:OBJECTIVE:The generic STarT Back 5-item screening tool (STarT-G) is used to manage chronic pain in the lower back and elsewhere. This study evaluated the validity of the Japanese version of this generic screening tool. MATERIALS AND METHODS:Japanese participants between the ages of 20 and 64 years completed online sur...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S129585
更新日期:2017-02-24 00:00:00
abstract::Purpose: Although amiodarone is classified as a Vaughan-Williams class Ⅲ antiarrhythmic drug, it has inhibitory effects on voltage-gated sodium and calcium channels and on β-adrenergic receptors. Given these pharmacological profiles, amiodarone may have analgesic properties. Most patients who are prescribed amiodarone...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S196480
更新日期:2019-06-06 00:00:00
abstract:BACKGROUND:No proof of efficacy, in the form of a randomized controlled trial (RCT), exists to support pulsed radiofrequency (PRF) treatment of the dorsal root ganglion (DRG) for chronic lumbar radicular (CLR) pain. We determined the feasibility of a larger trial (primary objective), and also explored the efficacy of P...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S55749
更新日期:2014-01-10 00:00:00
abstract:BACKGROUND:Opioid analgesics are effective for postsurgical pain but are associated with opioid-related adverse events, creating a significant clinical and economic burden. Gastrointestinal surgery patients are at high risk for opioid-related adverse events. We conducted a study to assess the impact of an opioid-sparin...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S46467
更新日期:2013-07-18 00:00:00
abstract:Background:While the concomitant administration of painful and rewarding stimuli tends to reduce the perception of one another, recent evidence shows that pleasant pain relief is experience after the interruption of noxious stimuli. On neurobiological grounds, these opponent processes should translate into decreased ac...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S248056
更新日期:2020-06-08 00:00:00
abstract:Objectives:The primary aim was to assess the psychometric properties (including internal consistency, construct validity, criterion validity, criterion-group validity and responsiveness) of the Fear of Pain Questionnaire (FOPQ) for adolescents (FOPQ-A) and parents (FOPQ-P) translated to Brazilian Portuguese (BrP). The ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S199120
更新日期:2019-08-07 00:00:00
abstract::Background: Chronic neuropathic pain (NP) is a complex disease that results from damage or presumed damage to the somatosensory nervous system. Current treatment regimens are often ineffective. The major impediment in developing effective treatments is our limited understanding of the underlying mechanisms. Preclinica...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S209657
更新日期:2019-08-02 00:00:00
abstract:BACKGROUND:Even though pain is a subjective phenomenon, its objective evaluation in humans is important because subjects requiring pain evaluation may be unable to describe their pain intensity because of decreased awareness or impaired cognitive function. Previous reports indicate that the perfusion index (PI), which ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S57140
更新日期:2014-02-10 00:00:00
abstract:Background:Many aspects of study conduct impact the observed effect size of treatment. Data were utilized from a recently published meta-analysis of randomized, double-blind, placebo-controlled, clinical trials performed for the United States Food and Drug Administration (FDA) approval of full mu-agonist opioids for th...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S201751
更新日期:2019-11-20 00:00:00
abstract::Purpose: One of the main factor of cervical foraminal stenosis (CFS) is the hypertrophic change of the cervical facet joint. In order to analyze the connection between CFS and the facet joint hypertrophy, we devised a new morphological parameter, called the cervical facet joint cross-sectional area (CFJA). The CFJA ha...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S204567
更新日期:2019-04-24 00:00:00
abstract:Objectives:Pain is reported as one of the most common and burdensome symptoms for children with cancer. Pain catastrophizing is clearly related to pain intensity and disability. Catastrophizing in parents is associated with both child functioning and parent distress. The Pain Catastrophizing Scale for Parents (PCS-P) r...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S193164
更新日期:2019-03-18 00:00:00
abstract:Purpose:Spinal cord stimulation (SCS) is a drug-free treatment for chronic neuropathic pain. Recent SCS technology can record evoked compound action potentials (ECAPs) in the spinal cord during therapy and utilize features of the sensed ECAP to optimize the SCS. The purpose of this work is to characterize the relevant ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S289098
更新日期:2020-12-04 00:00:00
abstract:OBJECTIVE:Patient controlled analgesia (PCA) is commonly used to provide analgesia following surgical procedures in the pediatric population. Morphine and hydromorphone remain the most commonly used opioids for PCA. Although both are effective, adverse effects may occur. When these adverse effects are unremitting or se...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S64497
更新日期:2014-08-13 00:00:00