Abstract:
OBJECTIVES:To determine whether X-ray, computed tomography (CT), bone scan, and clinical impression accurately reflect the level of vertebral fracture in patients about to undergo vertebroplasty. DESIGN:Retrospective observational study, utilizing patient inpatient notes, referral correspondence, and clinicians' private notes. SETTING:Single center - all patients referred to one pain medicine physician for vertebroplasty who subsequently had the procedure. PARTICIPANTS:All patients referred to a pain physician (PJG) over a 4-year period, who had a presumptive diagnosis of vertebral fracture(s) from the referring consultant physician, based on imaging other than magnetic resonance imaging (MRI) and clinical impression. Participants then had an MRI and subsequent vertebroplasty under the care of the pain physician. Participants were identified retrospectively from the vertebroplasty procedure list. INTERVENTION:Nil. MAIN OUTCOME MEASURE:Number of cases in which the MRI identified a different level of pathology than X-ray, CT, bone scan, and clinical impression. RESULTS:In 50% (28/56) of patients MRI identified a fracture at a different level to that which was presumed to be the cause of patient pain on the basis of X-ray, CT, and clinical impression. CONCLUSION:MRI is an essential investigation to determine accurately the level of fracture in osteoporotic patients. Studies on the effectiveness of treatment of vertebral fractures that do not utilize MRI in every case are unlikely to be accurate.
journal_name
J Pain Resjournal_title
Journal of pain researchauthors
Graziotti PJ,Graziotti CR,Sangster AMdoi
10.2147/JPR.S32151subject
Has Abstractpub_date
2013-05-10 00:00:00pages
359-65issn
1178-7090pii
jpr-6-359journal_volume
6pub_type
杂志文章abstract:Background:Transversus abdominis plane (TAP) block can provide effective analgesia for abdominal surgery. However, many randomized controlled trials (RCTs) have shown controversial results in hysterectomy. We conducted a meta-analysis of RCTs to investigate the effectiveness of TAP block after hysterectomy. Methods:St...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S172828
更新日期:2018-10-18 00:00:00
abstract:Purpose:The study aimed at the evaluation of the impact of intravenous (IV) dexamethasone on efficacy and duration of analgesia of paravertebral block (PVB) in patients undergoing modified radical mastectomy (MRM). Patients and methods:This randomized, double-blind controlled trial included 50 patients with breast can...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S181788
更新日期:2018-12-19 00:00:00
abstract:BACKGROUND:The objective of this study was to assess the safety, tolerability, and preliminary efficacy of NGX-4010, a capsaicin 8% patch, following pretreatment with three different topical anesthetics in patients with peripheral neuropathic pain. METHODS:This open-label, multicenter study enrolled 117 patients with ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S25272
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:Frequent chronic local pain can develop into chronic widespread pain (CWP). The spread of pain is correlated with pain intensity, anxiety, and depression, conditions that ultimately lead to a poor quality of life. Knowledge is incomplete about CWP's etiology, although it has been suggested that both centra...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S125667
更新日期:2017-03-13 00:00:00
abstract:PURPOSE:Since receiving a warning from the US Food and Drug Administration (FDA) about injection of corticosteroids into the epidural space having serious adverse events, we have sought alternative medications for injection at this site. Hyaluronic acid (HA) has anti-adhesive, anti-inflammatory, and lubricating propert...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S122861
更新日期:2017-01-25 00:00:00
abstract:UNLABELLED:Postsurgical pain management remains a significant challenge. Liposome bupivacaine, as part of a multimodal analgesic regimen, has been shown to significantly reduce postsurgical opioid consumption, hospital length of stay (LOS), and hospitalization costs in gastrointestinal (GI) surgery, compared with intra...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S63764
更新日期:2014-06-24 00:00:00
abstract:Objectives:Pain is reported as one of the most common and burdensome symptoms for children with cancer. Pain catastrophizing is clearly related to pain intensity and disability. Catastrophizing in parents is associated with both child functioning and parent distress. The Pain Catastrophizing Scale for Parents (PCS-P) r...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S193164
更新日期:2019-03-18 00:00:00
abstract::Ultrasound-guided cervical nerve root block is the technique of injecting local anesthetic or steroid into the intertubercular groove outside of the cervical foramen under real-time ultrasound guidance. It has established diagnostic and therapeutic employment for patients suffering symptoms caused by cervical disc dis...
journal_title:Journal of pain research
pub_type:
doi:10.2147/JPR.S272829
更新日期:2020-10-14 00:00:00
abstract:PURPOSE:This paper aimed to investigate motor proficiency in fine and gross motor function, with a focus on reaction time (RT) and movement skill, in patients with fibromyalgia (FM) and chronic fatigue syndrome (CFS) compared to healthy controls (HC). METHODS:A total of 60 individuals (20 CFS, 20 FM, and 20 HC), age 1...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S127038
更新日期:2017-02-07 00:00:00
abstract:Background:Patients living with chronic upper limb and neck (ULN) pain are reliant on often ineffective therapies as they face limited options for effective long-term treatment. Objective:Prospective clinical studies have demonstrated that high-frequency spinal cord stimulation at 10 kHz (10 kHz SCS) is effective in t...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S257071
更新日期:2020-06-15 00:00:00
abstract::Diabetic peripheral neuropathy (DPN) represents significant burdens to many patients and the public health-care system. Patients with diabetes in rural areas have higher risk of developing complications and having less access to proper treatment. We studied a rural population of patients with diabetes who attended a p...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S129139
更新日期:2017-04-07 00:00:00
abstract:Background:While the concomitant administration of painful and rewarding stimuli tends to reduce the perception of one another, recent evidence shows that pleasant pain relief is experience after the interruption of noxious stimuli. On neurobiological grounds, these opponent processes should translate into decreased ac...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S248056
更新日期:2020-06-08 00:00:00
abstract:BACKGROUND:Several studies have illustrated that multisite pain is more frequent than single pain site, and it is associated with an array of negative consequences. However, there is limited knowledge available about the potential factors associated with multisite pain in the elderly general population. OBJECTIVE:This...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S143060
更新日期:2017-08-23 00:00:00
abstract::Advances in intrathecal analgesia and intrathecal drug delivery systems have allowed for a range of medications to be used in the control of pain and spasticity. This technique allows for reduced medication doses that can decrease the side effects typically associated with oral or parenteral drug delivery. Recent expe...
journal_title:Journal of pain research
pub_type: 杂志文章,评审
doi:10.2147/JPR.S37591
更新日期:2014-11-06 00:00:00
abstract::Temporal sensory summation of pain (TSSP) is a proxy measure of windup in humans and results in increased ratings of pain caused by a repetitive, low-frequency noxious stimulus. Aftersensations (ASs) are pain sensations that remain after TSSP has been induced. We examined the within-session and across-session variabil...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S18105
更新日期:2011-01-01 00:00:00
abstract::Rotator-cuff tears (RCTs) are typically associated with chronic pain. The most common treatment for reducing pain is the injection of cortisone into the injury site. An alternative and increasingly used technique is the injection of autologous platelet-rich plasma (PRP). A limitation of cortisone is its pain relief is...
journal_title:Journal of pain research
pub_type:
doi:10.2147/JPR.S169647
更新日期:2018-10-09 00:00:00
abstract:Objective:This study investigated psychological characteristics of patients with chronic complex regional pain syndrome (CRPS) and examined relationships between psychosocial factors and pain severity. Methods:In total, 76 patients with CRPS, 95 patients with other types of chronic pain, 171 healthy controls, and 66 p...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S230394
更新日期:2020-02-13 00:00:00
abstract:PURPOSE:The treatment of central neuropathic pain remains amongst the biggest challenges for pain specialists. The main objective of this study was to assess gabapentin (GBP), amitriptyline (AMI), and carbamazepine (CARBA) for the treatment of a rodent central neuropathic pain model. METHODS:Male Sprague Dawley rats w...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S55201
更新日期:2013-12-17 00:00:00
abstract:Background:Despite the increasing prevalence of opioid use disorder (OUD) in pregnant women, there are limited studies on their anesthesia care and analgesic outcomes after cesarean delivery (CD). Methods:Patients with OUD on either buprenorphine or methadone maintenance therapy who underwent CD at our institution fro...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S284874
更新日期:2020-12-30 00:00:00
abstract::Calcitonin gene-related peptide (CGRP) is a major player in migraine pathophysiology, and CGRP monoclonal antibodies including fremanezumab may be a safe effective preventive therapy. Phase IIb studies in episodic migraine (EM) and chronic migraine (CM) demonstrated efficacy at both the monthly 225 mg and quarterly 67...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S166427
更新日期:2019-08-22 00:00:00
abstract:Background:It is becoming increasingly important to understand the mechanisms of spinal cord stimulation (SCS) in alleviating neuropathic pain as novel stimulation paradigms arise. Purpose:Additionally, the small anatomic scale of current SCS animal models is a barrier to more translational research. Methods:Using ch...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S139843
更新日期:2018-06-15 00:00:00
abstract:Purpose:Epidural analgesia provides safe and effective labor pain relief. However, labor episodic pain can occur during epidural analgesia, requiring epidural top-ups, and may result in decreased patient satisfaction. The primary aim of our study was to investigate the factors associated with labor episodic pain during...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S185073
更新日期:2019-02-15 00:00:00
abstract:Purpose:Primary dysmenorrhea (PD; menstrual pain without an identified organic cause) has been proposed as a possible risk factor for the development of chronic pelvic pain, but the mechanism through which this process occurs is unknown. One possible mechanism is central sensitization - alterations in the central nervo...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S283363
更新日期:2020-12-22 00:00:00
abstract:Background and Aims:Plantar fasciitis (PF) is the leading cause of heel pain in adults. This study was designed to evaluate the effect of hyaluronic acid (HA) injection in reducing the symptoms of PF, compared with corticosteroid (CS) injection as a conventional treatment. Methods:In this triple-blind, randomized, cli...
journal_title:Journal of pain research
pub_type:
doi:10.2147/JPR.S217419
更新日期:2020-01-14 00:00:00
abstract:Purpose:Fabry disease belongs to lysosomal storage disorders and can be successfully treated today. On the contrary, the correct diagnostic classification of its symptoms can be challenging and most patients suffer from pain for years, until they are diagnosed correctly. The aim of this project was to characterize pati...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S206223
更新日期:2019-07-23 00:00:00
abstract::Osteoarthritis (OA) is a common degenerative disease that affects the vast majority of the elderly and may eventually embark on the road of the total knee arthroplasty (TKA), although controversy still exists in the medical community about the best therapies for osteoarthritis. Compared with physical therapy, oral ana...
journal_title:Journal of pain research
pub_type: 杂志文章,评审
doi:10.2147/JPR.S260878
更新日期:2020-08-04 00:00:00
abstract:Background:Regional variations of opioid use have been reported from many countries. The objective of this study was to examine opioid prescribing patterns in Germany including low- and high-potency opioids (LPO and HPO) focusing on regional differences. Methods:Data source was the "Information system for health care ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S259009
更新日期:2020-10-07 00:00:00
abstract:Purpose:Although the use of opioids is increasing in South Korea, there have been no studies on the serious complications caused by the opioids. The aim of this study was to investigate the rare but serious complications through medicolegal analysis. Materials and Methods:From January 1994 to December 2019, we retrosp...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S256759
更新日期:2020-06-25 00:00:00
abstract::Phantom-limb pain (PLP) belongs among difficult-to-treat chronic pain syndromes. Treatment options for PLP are to a large degree implicated by the level of understanding the mechanisms and nature of PLP. Research and clinical findings acknowledge the neuropathic nature of PLP and also suggest that both peripheral as w...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S16733
更新日期:2012-01-01 00:00:00
abstract:Introduction:The sacroiliac joint (SIJ) has been estimated to contribute to pain in as much as 38% of cases of lower back pain. There are no clear diagnostic or treatment pathways. This article seeks to establish a clearer pathway and algorithm for treating patients. Methods:The literature was reviewed in order to rev...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S279390
更新日期:2020-12-08 00:00:00