Abstract:
:Advances in intrathecal analgesia and intrathecal drug delivery systems have allowed for a range of medications to be used in the control of pain and spasticity. This technique allows for reduced medication doses that can decrease the side effects typically associated with oral or parenteral drug delivery. Recent expert panel consensus guidelines have provided care paths in the treatment of nociceptive, neuropathic, and mixed pain syndromes. While the data for pain relief, adverse effect reduction, and cost-effectiveness with cancer pain control are compelling, the evidence is less clear for noncancer pain, other than spasticity. Physicians should be aware of mechanical, pharmacological, surgical, and patient-specific complications, including possible granuloma formation. Newer intrathecal drug delivery systems may allow for better safety and quality of life outcomes.
journal_name
J Pain Resjournal_title
Journal of pain researchauthors
Bottros MM,Christo PJdoi
10.2147/JPR.S37591subject
Has Abstractpub_date
2014-11-06 00:00:00pages
615-26issn
1178-7090pii
jpr-7-615journal_volume
7pub_type
杂志文章,评审abstract::Low back pain in patients with myofascial pain syndrome is characterized by painful active myofascial trigger points (ATPs) in muscles. This article reviews a novel, noninvasive modality that combines simultaneous imaging and treatment, thus taking advantage of the electrodermal information available from imaged ATPs ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S47540
更新日期:2013-06-25 00:00:00
abstract:BACKGROUND:Opioids and other controlled substances prescribed for chronic pain are associated with abuse, addiction, and death, prompting national initiatives to identify safe and effective pain management strategies including topical analgesics. METHODS:This prospective, observational study evaluated changes from bas...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S143513
更新日期:2017-10-03 00:00:00
abstract:Purpose:To identify risk factors for pain after transarterial chemoembolization with drug-eluting beads (DEB-TACE) for hepatocellular carcinoma (HCC). Patients and Methods:In this retrospective study, a total of 118 consecutive patients who underwent DEB-TACE between June 2016 and May 2019 with post-TACE pain were inc...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S246197
更新日期:2020-03-27 00:00:00
abstract:Objective:To report a rare case of spontaneous fusion (SF) following cervical disc arthroplasty (CDA), to review the related literature, and to propose a new measure to prevent it. Methods:The course of a patient with SF is described here. The potential causes, risk factors, and preventive measure of SF after CDA publ...
journal_title:Journal of pain research
pub_type:
doi:10.2147/JPR.S242646
更新日期:2020-04-21 00:00:00
abstract:INTRODUCTION:Pain is a common symptom presented in the emergency department (ED) although it is often underestimated, poorly evaluated and treated. The application of a protocol for timely pain management ensured by the nurse can avoid the delays in the analgesic treatment and improve the patient's quality of waiting. ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S138850
更新日期:2017-10-16 00:00:00
abstract:BACKGROUND:Even though pain is a subjective phenomenon, its objective evaluation in humans is important because subjects requiring pain evaluation may be unable to describe their pain intensity because of decreased awareness or impaired cognitive function. Previous reports indicate that the perfusion index (PI), which ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S57140
更新日期:2014-02-10 00:00:00
abstract:Background:This study evaluates the reporting quality of randomized controlled trials (RCTs) on acupuncture use for the treatment of postherpetic neuralgia and explores related factors. Methods:The following six databases PubMed, Embase, Cochrane Library, VIP, CNKI, and SinoMed, were systematically searched from their...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S210471
更新日期:2019-07-29 00:00:00
abstract:Background:Erector spinae plane block (ESPB) as a new trunk fascia block technique was proposed in 2016. ESPB has aroused the interest of many nerve block experts. However, there are few clinical studies on ESPB for lumbar surgery, and its effectiveness and safety are controversial. The goal of this review is to summar...
journal_title:Journal of pain research
pub_type: 杂志文章,评审
doi:10.2147/JPR.S256205
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Very few studies have discussed transforaminal endoscopic discectomy (TED) in the treatment of common peroneal nerve paralysis induced by lumbar disk herniation (LDH). This study aimed to evaluate the efficacy of TED in the treatment of LDH combined with common peroneal nerve paralysis. MATERIALS AND METHOD...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S120463
更新日期:2017-01-05 00:00:00
abstract::Multisite pain, or pain that occurs simultaneously at >1 anatomical site, is more prevalent than single-site pain. While multisite pain affects over half of older adults, it remains an understudied pain entity that may have important functional implications in an aging population. Greater understanding of this complex...
journal_title:Journal of pain research
pub_type: 杂志文章,评审
doi:10.2147/JPR.S192755
更新日期:2019-03-29 00:00:00
abstract::The objective of this study was to evaluate the relationship between magnetic resonance imaging (MRI) findings and previous low back pain (LBP) in participants without current LBP. Current LBP was defined as LBP during the past month. Previous LBP was defined as a history of medical consultation for LBP. Ninety-one pa...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S122380
更新日期:2016-12-29 00:00:00
abstract::Purpose: We aimed to explore the characteristics, and real-life therapeutic management of patients with breakthrough cancer pain (BTcP) caused by bone metastases in Spain, and to evaluate physicians' opinion of and satisfaction with prescribed BTcP therapy. Participants and methods: For the purposes of this study, an ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S194881
更新日期:2019-07-12 00:00:00
abstract:BACKGROUND:Several studies have illustrated that multisite pain is more frequent than single pain site, and it is associated with an array of negative consequences. However, there is limited knowledge available about the potential factors associated with multisite pain in the elderly general population. OBJECTIVE:This...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S143060
更新日期:2017-08-23 00:00:00
abstract:Purpose:The study aimed at the evaluation of the impact of intravenous (IV) dexamethasone on efficacy and duration of analgesia of paravertebral block (PVB) in patients undergoing modified radical mastectomy (MRM). Patients and methods:This randomized, double-blind controlled trial included 50 patients with breast can...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S181788
更新日期:2018-12-19 00:00:00
abstract::Recently, attention to the lifestyle of patients has been rapidly increasing in the field of pain therapy, particularly with regard to the role of nutrition in pain development and its management. In this review, we summarize the latest findings on the role of nutrition and nutraceuticals, microbiome, obesity, soy, om...
journal_title:Journal of pain research
pub_type: 杂志文章,评审
doi:10.2147/JPR.S115068
更新日期:2016-12-08 00:00:00
abstract::This open-label, phase 3b study (ClinicalTrials.gov Identifier: NCT00983073) evaluated the effectiveness, and tolerability of tapentadol for severe, chronic osteoarthritis knee pain that was inadequately managed with World Health Organization (WHO) Step I or II analgesics or co-analgesics, or that was not treated with...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S30540
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Sports-related injuries, such as sprains and strains, commonly occur during exercise and athletic events. Current therapy includes nonsteroidal anti-inflammatory drugs (NSAIDs), which have a high incidence of upper gastrointestinal side effects. The present study assessed the efficacy and safety of the diclo...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S15380
更新日期:2011-03-07 00:00:00
abstract:Background:With the increase in life expectancy seen throughout the world, the prevalence of degenerative spinal pathology and surgery to treat it has increased. Spinal surgery under general anesthesia leads to various problems and complications, especially in patients with numerous medical comorbidities or elderly pat...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S227212
更新日期:2020-01-21 00:00:00
abstract:PURPOSE:Conditioned pain modulation (CPM) is an experimental approach for probing endogenous analgesia by which one painful stimulus (the conditioning stimulus) may inhibit the perceived pain of a subsequent stimulus (the test stimulus). Animal studies suggest that CPM is mediated by a spino-bulbo-spinal loop using obj...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S65607
更新日期:2014-11-26 00:00:00
abstract:BACKGROUND:Waiting list management at chronic pain clinics has become a serious problem throughout Canada. We analyzed the waiting list at the Centre hospitalier de l'Université de Montréal (CHUM) Pain Centre. METHODS:The present study is an observational, prospective study. We used a specifically designed survey ques...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S46118
更新日期:2013-07-08 00:00:00
abstract:OBJECTIVE:Chronic pelvic pain (CPP) is widely acknowledged as a common problem with significant consequences for those diagnosed with this condition. There is a lack of studies with good sample size that provide a comprehensive psychological profile of women presenting to specialist chronic pain clinics. Therefore, the...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S115065
更新日期:2016-11-16 00:00:00
abstract:OBJECTIVE:Lymphocyte apoptosis in critical illness is associated with immunosuppression. We explored for the first time the associations between pain ratings and expression of the apoptotic receptor Fas on B and T cells in critically ill patients and the potential mediating effects of adrenocorticotropic hormone (ACTH)...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S118105
更新日期:2017-01-13 00:00:00
abstract:Background:Low back pain is a prevalent symptom that occurs in all age of people, whereas the pathogenesis is unknown. Iliopsoas tendinopathy is an increasingly recognized hip disorder that may contribute to low back pain. Our purpose is to evaluate the effect of ultrasound-guided local injection of anesthetic and ster...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S281880
更新日期:2020-11-20 00:00:00
abstract::Purpose: The study aimed to evaluate the analgesic efficiency of dexmedetomidine (DEX) when added to levobupivacaine in continuous ultrasound-guided serratus anterior plane block (SAPB) performed at the end of major thoracic surgery. Methods: This randomized, double-blind trial included 50 adults undergoing thoracic s...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S195431
更新日期:2019-04-30 00:00:00
abstract:Background:The prevalence of neuropathic pain (NeP) has been estimated within specific health conditions; however, there are no published data on its broad prevalence in the US. The current exploratory study addresses this gap using the validated PainDetect questionnaire as a screener for probable NeP in a general-popu...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S127014
更新日期:2017-11-01 00:00:00
abstract:Background:Regional variations of opioid use have been reported from many countries. The objective of this study was to examine opioid prescribing patterns in Germany including low- and high-potency opioids (LPO and HPO) focusing on regional differences. Methods:Data source was the "Information system for health care ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S259009
更新日期:2020-10-07 00:00:00
abstract::Ultrasound-guided cervical nerve root block is the technique of injecting local anesthetic or steroid into the intertubercular groove outside of the cervical foramen under real-time ultrasound guidance. It has established diagnostic and therapeutic employment for patients suffering symptoms caused by cervical disc dis...
journal_title:Journal of pain research
pub_type:
doi:10.2147/JPR.S272829
更新日期:2020-10-14 00:00:00
abstract:Purpose:To explore the role of cervical sagittal alignment in the occurrence of adjacent-level ossification development (ALOD) in patients who underwent anterior cervical discectomy fusion with self-locking stand-alone polyetheretherketone cage, and the relationship between cervical sagittal alignment and clinical outc...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S160472
更新日期:2018-07-20 00:00:00
abstract::Temporal sensory summation of pain (TSSP) is a proxy measure of windup in humans and results in increased ratings of pain caused by a repetitive, low-frequency noxious stimulus. Aftersensations (ASs) are pain sensations that remain after TSSP has been induced. We examined the within-session and across-session variabil...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S18105
更新日期:2011-01-01 00:00:00
abstract:Purpose:Brachial plexopathy can sometimes cause severe chronic pain. There are many possible treatments for such neuropathic pain, including neuromodulation. However, rigorous scientific evidence on the usefulness of spinal cord stimulation (SCS) is still scarce. Here, we report the use of high-frequency (10 kHz) SCS (...
journal_title:Journal of pain research
pub_type:
doi:10.2147/JPR.S168031
更新日期:2018-11-27 00:00:00