Age-related and sex-related changes in perfusion index in response to noxious electrical stimulation in healthy subjects.

abstract：Background:The prevalence of neuropathic pain (NeP) has been estimated within specific health conditions; however, there are no published data on its broad prevalence in the US. The current exploratory study addresses this gap using the validated PainDetect questionnaire as a screener for probable NeP in a general-popu...

journal_title：Journal of pain research

authors： DiBonaventura MD,Sadosky A,Concialdi K,Hopps M,Kudel I,Parsons B,Cappelleri JC,Hlavacek P,Alexander AH,Stacey BR,Markman JD,Farrar JT

更新日期：2017-11-01 00:00:00

abstract：:Different pericardial catheters have been suggested as an effective alternative method for drainage of pericardial effusion. The aim of this study was to determine the performance, pain, and quality of life on use of central venous catheter (CVC) for drainage of pericardial effusion in patients undergoing open heart s...

journal_title：Journal of pain research

authors： Ghods K,Razavi MR,Forozeshfard M

更新日期：2016-10-31 00:00:00

abstract：OBJECTIVE:Lymphocyte apoptosis in critical illness is associated with immunosuppression. We explored for the first time the associations between pain ratings and expression of the apoptotic receptor Fas on B and T cells in critically ill patients and the potential mediating effects of adrenocorticotropic hormone (ACTH)...

journal_title：Journal of pain research

authors： Papathanassoglou E,Mpouzika MD,Giannakopoulou M,Bozas E,Middleton N,Tsiaousis G,Karabinis A

更新日期：2017-01-13 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Major abdominal cancer surgeries are associated with significant perioperative mortality and morbidity due to myocardial ischemia and infarction. This study examined the effect of perioperative patient controlled epidural analgesia (PCEA) on occurrence of ischemic cardiac injury in ischemic pa...

journal_title：Journal of pain research

authors： Mohamad MF,Mohammad MA,Hetta DF,Ahmed EH,Obiedallah AA,Elzohry AAM

更新日期：2017-04-12 00:00:00

abstract：Background:Thoracoscopic surgery (TS) has been performed as a minimally invasive procedure since the beginning of the 1990s. This has led to a dramatic change in the postoperative condition of these patients, facilitating early ambulation and easier management of postoperative pain. However, empirical evidence on posto...

journal_title：Journal of pain research

authors： Kuroda H,Mizuno H,Dejima H,Watanabe K,Yoshida T,Naito Y,Sakao Y

更新日期：2017-11-15 00:00:00

abstract：PURPOSE:The treatment of central neuropathic pain remains amongst the biggest challenges for pain specialists. The main objective of this study was to assess gabapentin (GBP), amitriptyline (AMI), and carbamazepine (CARBA) for the treatment of a rodent central neuropathic pain model. METHODS:Male Sprague Dawley rats w...

journal_title：Journal of pain research

authors： Castel A,Vachon P

更新日期：2013-12-17 00:00:00

abstract：:Temporal sensory summation of pain (TSSP) is a proxy measure of windup in humans and results in increased ratings of pain caused by a repetitive, low-frequency noxious stimulus. Aftersensations (ASs) are pain sensations that remain after TSSP has been induced. We examined the within-session and across-session variabil...

journal_title：Journal of pain research

authors： Alappattu MJ,Bishop MD,Bialosky JE,George SZ,Robinson ME

更新日期：2011-01-01 00:00:00

abstract：:Topical treatments of localized neuropathic pain syndromes in general are mostly neglected, mainly due to the fact that most pain physicians expect that a topical formulation needs to result in a transdermal delivery of the active compounds. On the basis of the practical experience, this study brings forth a new, some...

journal_title：Journal of pain research

authors： Keppel Hesselink JM,Kopsky DJ,Sajben N

更新日期：2016-10-03 00:00:00

abstract：BACKGROUND:Large interindividual differences in clinical responses to opioids and the variable susceptibility to abuse of this class of drugs make their use problematic. We lack a full understanding of the factors responsible for these differences. Dietary factors including methyl donor content have been noted to alter...

journal_title：Journal of pain research

authors： Liang DY,Sun Y,Clark JD

更新日期：2013-01-01 00:00:00

abstract：Purpose:To examine the trends of analgesic prescribing at public tertiary hospital outpatient settings and explore the patterns of their utilization in nonsteroidal anti-inflammatory drugs (NSAIDs), tramadol, and opioid patients. Patients and methods:This cross-sectional study was conducted from 2010 to 2016 using the...

journal_title：Journal of pain research

authors： Zin CS,Nazar NI,Rahman NS,Alias NE,Ahmad WR,Rani NS,Cardosa MS,Ng KS,Ye FL

更新日期：2018-09-20 00:00:00

abstract：:Adolescent low back pain (ALBP) is a common form of adolescent morbidity which remains poorly understood. When attempting a meta-analysis of observational studies into ALBP, in an effort to better understand associated risk factors, it is important that the studies involved are homogenic, particularly in terms of the ...

journal_title：Journal of pain research

authors： Milanese S,Grimmer-Somers K

更新日期：2010-05-17 00:00:00

abstract：OBJECTIVES:Effective postoperative pain management is crucial in the care of surgical patients. Opioids, which are commonly used in managing postoperative pain, have a potential for tolerance and addiction, along with sedating side effects. Gabapentin's use as a multimodal analgesic regimen to treat neuropathic pain ha...

journal_title：Journal of pain research

authors： Arumugam S,Lau CS,Chamberlain RS

更新日期：2016-09-12 00:00:00

abstract：Background:Femoral nerve block (FNB) has been considered as an excellent analgesic modality in total knee arthroplasty (TKA) pain control. However, relatively high concentration of ropivacaine could lead to quadriceps muscle weakness and increase the risk of postoperative falls. Objective:This double-blinded randomize...

journal_title：Journal of pain research

authors： Yang X,Kang W,Xiong W,Lu D,Zhou Z,Chen X,Zhou X,Feng X

更新日期：2019-12-17 00:00:00

abstract：Background:The ability to accurately diagnose and objectively localize pain generators in chronic pain sufferers remains a major clinical challenge since assessment relies on subjective patient complaints and relatively non-specific diagnostic tools. Developments in clinical molecular imaging, including advances in ima...

journal_title：Journal of pain research

authors： Cipriano PW,Lee SW,Yoon D,Shen B,Tawfik VL,Curtin CM,Dragoo JL,James ML,McCurdy CR,Chin FT,Biswal S

更新日期：2018-10-12 00:00:00

abstract：Background:Postherpetic neuralgia (PHN) refers to pain which remains after the healing of rashes from herpes zoster. Previous literatures have shown that acupuncture has potential benefits for PHN, but evidence remains lacking. Thus, we have performed a systematic review and meta-analysis to identify the effectiveness ...

journal_title：Journal of pain research

authors： Pei W,Zeng J,Lu L,Lin G,Ruan J

更新日期：2019-07-16 00:00:00

abstract：Background and Aims:Plantar fasciitis (PF) is the leading cause of heel pain in adults. This study was designed to evaluate the effect of hyaluronic acid (HA) injection in reducing the symptoms of PF, compared with corticosteroid (CS) injection as a conventional treatment. Methods:In this triple-blind, randomized, cli...

journal_title：Journal of pain research

authors： Raeissadat SA,Nouri F,Darvish M,Esmaily H,Ghazihosseini P

更新日期：2020-01-14 00:00:00

abstract：Aim:Operant conditioning has long been believed to influence the pain experience through a psychological reward pathway. This study was formulated to test the hypothesis that pain sensitivity may be enhanced >3 months if a monetary reward works as a reinforcement. Methods:Forty healthy subjects volunteered to particip...

journal_title：Journal of pain research

authors： Shiro Y,Ikemoto T,Hayashi K,Arai YC,Deie M,Ueno T

更新日期：2018-10-04 00:00:00

abstract：Purpose:Spinal cord stimulation (SCS) is a drug-free treatment for chronic neuropathic pain. Recent SCS technology can record evoked compound action potentials (ECAPs) in the spinal cord during therapy and utilize features of the sensed ECAP to optimize the SCS. The purpose of this work is to characterize the relevant ...

journal_title：Journal of pain research

authors： Chakravarthy K,Bink H,Dinsmoor D

更新日期：2020-12-04 00:00:00

abstract：Introduction:Sickle cell disease (SCD) is an inherited blood disorder characterized by abnormally shaped sickle cells. The hallmark of this disease is intermittent, painful vaso-occlusive episodes (VOE), but a subset of individuals with SCD experience chronic pain. The mechanism of transition to chronic pain is not wel...

journal_title：Journal of pain research

authors： Bakshi N,Lukombo I,Belfer I,Krishnamurti L

更新日期：2018-02-23 00:00:00

abstract：Background:The objective of this study was to compare the efficacy of calcitonin with diclofenac sodium in the treatment of patients with nonspecific low back pain (LBP) and type I Modic changes (MC1). Patients and methods:The study was a retrospective observational study with 109 patients who had nonspecific LBP and ...

journal_title：Journal of pain research

authors： Zhou J,Li T,Li L,Xue Y

更新日期：2018-07-17 00:00:00

abstract：Background:While the concomitant administration of painful and rewarding stimuli tends to reduce the perception of one another, recent evidence shows that pleasant pain relief is experience after the interruption of noxious stimuli. On neurobiological grounds, these opponent processes should translate into decreased ac...

journal_title：Journal of pain research

authors： Bitar N,Dugré JR,Marchand S,Potvin S

更新日期：2020-06-08 00:00:00

abstract：Purpose:The upregulation of spinal NMDA receptor is a crucial mechanism in remifentanil-induced hyperalgesia (RIH). Wnt3a/β-catenin pathway plays an important role in neuropathic pain. We hypothesized that wnt3a inhibitor (iwp-2) could downregulate the expression of NR2B subunit in NMDA receptor, in order to relieve R...

journal_title：Journal of pain research

authors： Gao Y,Zhou S,Pan Y,Gu L,He Y,Sun J

更新日期：2020-05-19 00:00:00

abstract：:Phantom-limb pain (PLP) belongs among difficult-to-treat chronic pain syndromes. Treatment options for PLP are to a large degree implicated by the level of understanding the mechanisms and nature of PLP. Research and clinical findings acknowledge the neuropathic nature of PLP and also suggest that both peripheral as w...

journal_title：Journal of pain research

authors： Knotkova H,Cruciani RA,Tronnier VM,Rasche D

更新日期：2012-01-01 00:00:00

abstract：:Cervical intervertebral disc has long been considered a common source of neck pain. However, the pain caused by the disc itself has not been clearly defined so far, and its diagnosis and treatment has always been controversial. Degenerative cervical disc has a rich supply of nerve fibers, is prone to inflammatory reac...

journal_title：Journal of pain research

authors： Peng B,DePalma MJ

更新日期：2018-11-14 00:00:00

abstract：:Nocebo hyperalgesia has received sparse experimental attention compared to placebo analgesia. The aim of the present study was to investigate if personality traits and fear of pain could predict experimental nocebo hyperalgesia. One hundred and eleven healthy volunteers (76 females) participated in an experimental stu...

journal_title：Journal of pain research

authors： Aslaksen PM,Lyby PS

更新日期：2015-10-12 00:00:00

abstract：Introduction:The sacroiliac joint (SIJ) has been estimated to contribute to pain in as much as 38% of cases of lower back pain. There are no clear diagnostic or treatment pathways. This article seeks to establish a clearer pathway and algorithm for treating patients. Methods:The literature was reviewed in order to rev...

journal_title：Journal of pain research

authors： Falowski S,Sayed D,Pope J,Patterson D,Fishman M,Gupta M,Mehta P

更新日期：2020-12-08 00:00:00

abstract：Purpose:Pregabalin is indicated for postherpetic neuralgia (PHN) in multiple countries, including China. This analysis compared pregabalin efficacy and safety in Chinese and international patients with PHN. Patients and methods:Data from Chinese and international randomized, double-blind, placebo-controlled trials wer...

journal_title：Journal of pain research

authors： Parsons B,Pan X,Xie L,Chen Y,Ortiz M,Whalen E

更新日期：2018-09-03 00:00:00

abstract：Background:In 2016, the Centers for Disease Control and Prevention (CDC) released a guideline on opioid prescribing for primary care physicians. Patients with chronic pain receiving long-term opioid therapy were surveyed to assess the incidence and impact of opioid dose reduction following this guideline's promulgation...

journal_title：Journal of pain research

authors： Twillman RK,Hemmenway N,Passik SD,Thompson CA,Shrum M,DeGeorge MK

更新日期：2018-11-08 00:00:00

abstract：Background:The objective of this study was to compare the clinical and radiological outcomes between patients with or without axial symptoms (AS) and investigate the risk factors associated with AS by multivariate regression analysis in anterior cervical discectomy and fusion (ACDF). Materials and methods:The records ...

journal_title：Journal of pain research

authors： Zhou J,Li L,Li T,Xue Y

更新日期：2018-10-26 00:00:00

abstract：BACKGROUND:Opioids and other controlled substances prescribed for chronic pain are associated with abuse, addiction, and death, prompting national initiatives to identify safe and effective pain management strategies including topical analgesics. METHODS:This prospective, observational study evaluated changes from bas...

journal_title：Journal of pain research

authors： Gudin JA,Brennan MJ,Harris ED,Hurwitz PL,Dietze DT,Strader JD

更新日期：2017-10-03 00:00:00