Abstract:
:Purpose: One of the main factor of cervical foraminal stenosis (CFS) is the hypertrophic change of the cervical facet joint. In order to analyze the connection between CFS and the facet joint hypertrophy, we devised a new morphological parameter, called the cervical facet joint cross-sectional area (CFJA). The CFJA has not yet been investigated for its association with CFS. We hypothesized that the CFJA is an important morphologic parameter in the diagnosis of CFS. Patients and methods: All patients over 50 years of age were included. Data regarding the CFJA were collected from 160 subjects with CFS. A total of 162 control individuals underwent cervical spine magnetic resonance imaging (CMRI) as part of a routine medical examination. Axial T2-weighted CMRI images were acquired from all subjects. We used a picture archiving system to analyze the cross-sectional area of the bone margin of the cervical facet joint at the level of the most stenotic cervical spine in the axial plane. Results: The average CFJA was 109.07±20.91 mm2 in the control group, and 126.75±22.59 mm2 in the CFS group. The CFS group was found to have significantly higher levels of the CFJA (p<0.001) than the control group. ROC curve estimation was used to verify the validity of the CFJA as a new predictor of CFS. In the CFS group, the best cut off-point was 113.14 mm2, with sensitivity =70.6%, specificity =68.6%, and AUC =0.72 (95% CI, 0.66-0.77). Conclusions: CFJA high values were closely associated with a possibility of CFS. We concluded CFJA is easy to use, fast, and useful new morphological parameter to predict CFS.
journal_name
J Pain Resjournal_title
Journal of pain researchauthors
An SJ,Hong SJ,Kim YU,Lee YKdoi
10.2147/JPR.S204567subject
Has Abstractpub_date
2019-04-24 00:00:00pages
1325-1330issn
1178-7090pii
204567journal_volume
12pub_type
杂志文章abstract::Background: Chronic neuropathic pain (NP) is a complex disease that results from damage or presumed damage to the somatosensory nervous system. Current treatment regimens are often ineffective. The major impediment in developing effective treatments is our limited understanding of the underlying mechanisms. Preclinica...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S209657
更新日期:2019-08-02 00:00:00
abstract::Adolescent low back pain (ALBP) is a common form of adolescent morbidity which remains poorly understood. When attempting a meta-analysis of observational studies into ALBP, in an effort to better understand associated risk factors, it is important that the studies involved are homogenic, particularly in terms of the ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/jpr.s10025
更新日期:2010-05-17 00:00:00
abstract:Purpose:Epidural analgesia provides safe and effective labor pain relief. However, labor episodic pain can occur during epidural analgesia, requiring epidural top-ups, and may result in decreased patient satisfaction. The primary aim of our study was to investigate the factors associated with labor episodic pain during...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S185073
更新日期:2019-02-15 00:00:00
abstract:Background:Transient receptor potential ankyrin 1 (TRPA1) is a non-selective cation channel expressed by a subset of nociceptive neurons that acts as a multimodal receptor. Its activity contributes to modulate nociceptive transmission in acute inflammatory pain. However, the role of this channel in chronic pain has bee...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S153671
更新日期:2017-12-27 00:00:00
abstract::The objective of this study was to evaluate the relationship between magnetic resonance imaging (MRI) findings and previous low back pain (LBP) in participants without current LBP. Current LBP was defined as LBP during the past month. Previous LBP was defined as a history of medical consultation for LBP. Ninety-one pa...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S122380
更新日期:2016-12-29 00:00:00
abstract:Purpose:To investigate the ameliorative effects of Vitellaria paradoxa (VP) nut extract for an anterior cruciate ligament transection with medial meniscectomy (ACLT+MMx)-induced osteoarthritis (OA) in high-fat diet (HFD)-induced obese rats. Methods:The rats were fed by HFD for 5 weeks before surgery-induced OA. Rats w...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S228766
更新日期:2020-01-30 00:00:00
abstract:Purpose:The quadratus lumborum block (QLB) is a relatively new regional analgesic technique that could provide analgesia to the abdominal wall and reduce postoperative opioid consumption. We investigated the opioid-sparing effect of a unilateral lateral QLB in laparoscopic nephrectomy. Patients and Methods:A total of ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S257466
更新日期:2020-07-03 00:00:00
abstract:Purpose:The aim of this prospective study was to assess the behavior of emergency department (ED) nurses with regard to pain and their role in pain management in a real-life clinical setting. Methods:A total of 509 consecutive patients were enrolled during a 6-week period. A case-report form was used to collect data o...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S266087
更新日期:2020-09-22 00:00:00
abstract:BACKGROUND:Sports-related injuries, such as sprains and strains, commonly occur during exercise and athletic events. Current therapy includes nonsteroidal anti-inflammatory drugs (NSAIDs), which have a high incidence of upper gastrointestinal side effects. The present study assessed the efficacy and safety of the diclo...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S15380
更新日期:2011-03-07 00:00:00
abstract:Objectives:Estimate the prevalence of neuropathic pain (NeP) among chronic pain patients attending Brazilian hospitals and pain clinics in São Paulo, Ceara, and Bahia and explore clinical characteristics by subtypes: painful diabetic peripheral neuropathy (pDPN), central neuropathic pain (CNP), chronic low back pain wi...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S160504
更新日期:2019-01-07 00:00:00
abstract::Nocebo hyperalgesia has received sparse experimental attention compared to placebo analgesia. The aim of the present study was to investigate if personality traits and fear of pain could predict experimental nocebo hyperalgesia. One hundred and eleven healthy volunteers (76 females) participated in an experimental stu...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S91923
更新日期:2015-10-12 00:00:00
abstract:PURPOSE:The zona incerta (ZI) is below the ventral tier of the thalamus and has a strong influence selectively in higher-order thalamic relays. Although neuropathic pain has been suggested to result from reduced gamma-aminobutyric acid (GABA) and GABAergic signaling in the ZI, the mechanisms remain unclear. Here, the r...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S131104
更新日期:2017-05-11 00:00:00
abstract:OBJECTIVE:This systematic review aimed to assess the efficacy, effectiveness, safety, and tolerability of osteopathic manipulative treatment (OMT) in patients with headache. BACKGROUND:Migraine is one of the most common and disabling medical conditions. It affects more than 15% of the general population, causing high ...
journal_title:Journal of pain research
pub_type: 杂志文章,评审
doi:10.2147/JPR.S130501
更新日期:2017-03-14 00:00:00
abstract:Background:Low back pain is a prevalent symptom that occurs in all age of people, whereas the pathogenesis is unknown. Iliopsoas tendinopathy is an increasingly recognized hip disorder that may contribute to low back pain. Our purpose is to evaluate the effect of ultrasound-guided local injection of anesthetic and ster...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S281880
更新日期:2020-11-20 00:00:00
abstract:Purpose:Gabapentinoids are currently the mainstay of pharmacological treatments for patients with neuropathic pain. Little is known about the effects of this therapy on the integrity of neuronal networks, especially in patients with an already-damaged nervous system. Since gabapentinoids can worsen cognitive functions ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S162322
更新日期:2018-06-20 00:00:00
abstract::Purpose: Thirty percent of patients with postherpetic neuralgia (PHN) receiving conservative treatment report unsatisfactory pain relief. Epidural steroid injections (ESIs) are commonly used as a therapeutic intervention in these patients. In this study, we aimed to determine if there are variables that predict the ef...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S190646
更新日期:2019-04-23 00:00:00
abstract:OBJECTIVES:To determine whether X-ray, computed tomography (CT), bone scan, and clinical impression accurately reflect the level of vertebral fracture in patients about to undergo vertebroplasty. DESIGN:Retrospective observational study, utilizing patient inpatient notes, referral correspondence, and clinicians' priva...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S32151
更新日期:2013-05-10 00:00:00
abstract:Purpose:Primary dysmenorrhea (PD; menstrual pain without an identified organic cause) has been proposed as a possible risk factor for the development of chronic pelvic pain, but the mechanism through which this process occurs is unknown. One possible mechanism is central sensitization - alterations in the central nervo...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S283363
更新日期:2020-12-22 00:00:00
abstract::Osteoarthritis (OA) is the most prevalent arthritis worldwide and is characterized by chronic pain and impaired physical function. We hypothesized that heightened pain in hand OA could be reduced with duloxetine or pregabalin. In this prospective, randomized clinical study, we recruited 65 participants, aged 40-75 yea...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S147640
更新日期:2017-10-10 00:00:00
abstract::Rotator-cuff tears (RCTs) are typically associated with chronic pain. The most common treatment for reducing pain is the injection of cortisone into the injury site. An alternative and increasingly used technique is the injection of autologous platelet-rich plasma (PRP). A limitation of cortisone is its pain relief is...
journal_title:Journal of pain research
pub_type:
doi:10.2147/JPR.S169647
更新日期:2018-10-09 00:00:00
abstract:BACKGROUND:Oliceridine (TRV130), a novel μ-receptor G-protein pathway selective (μ-GPS) modulator, was designed to improve the therapeutic window of conventional opioids by activating G-protein signaling while causing low β-arrestin recruitment to the μ receptor. This randomized, double-blind, patient-controlled analge...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S137952
更新日期:2017-10-06 00:00:00
abstract:Background:Pain is a common and undertreated non-motor symptom in patients with Parkinson's disease (PD). Opioids have been seldom used in PD because they could worsen cognitive and motor functions. Objective:We aimed to assess efficacy and tolerability of tapentadol in PD patients. Methods:We retrospectively reviewe...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S164939
更新日期:2018-09-13 00:00:00
abstract:OBJECTIVE:Lymphocyte apoptosis in critical illness is associated with immunosuppression. We explored for the first time the associations between pain ratings and expression of the apoptotic receptor Fas on B and T cells in critically ill patients and the potential mediating effects of adrenocorticotropic hormone (ACTH)...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S118105
更新日期:2017-01-13 00:00:00
abstract:BACKGROUND:Diagnosis of fibromyalgia (FM), a chronic musculoskeletal condition characterized by widespread pain and a constellation of symptoms, remains challenging and is often delayed. METHODS:Random forest modeling of electronic medical records was used to identify variables that may facilitate earlier FM identific...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/jpr.s8256
更新日期:2015-06-10 00:00:00
abstract:Introduction:Cannabidiol (CBD) is reported to produce pain relief, but the clinically relevant cellular and molecular mechanisms remain uncertain. The TRPV1 receptor integrates noxious stimuli and plays a key role in pain signaling. Hence, we conducted in vitro studies, to elucidate the efficacy and mechanisms of CBD f...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S258433
更新日期:2020-09-11 00:00:00
abstract:BACKGROUND:Chronic low back pain (CLBP) and chronic neck pain (CNP) have become a serious medical and socioeconomic problem in recent decades. Patients suffering from chronic pain seem to have a higher prevalence of sleep disorders. PURPOSE:To calculate the prevalence of sleep deprivation in patients with CLBP and CNP...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S36386
更新日期:2013-01-01 00:00:00
abstract:Background:In 2016, the Centers for Disease Control and Prevention (CDC) released a guideline on opioid prescribing for primary care physicians. Patients with chronic pain receiving long-term opioid therapy were surveyed to assess the incidence and impact of opioid dose reduction following this guideline's promulgation...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S175402
更新日期:2018-11-08 00:00:00
abstract:Purposes:To investigate the prevalence of pain-related diagnoses in patients with dementia and evaluate the association of pain-related diagnoses with demographic characteristics and dementia subtypes. Patients and methods:In this population-based retrospective cohort study, participants were recruited from a cohort o...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S172875
更新日期:2018-09-03 00:00:00
abstract:Purpose:Brachial plexopathy can sometimes cause severe chronic pain. There are many possible treatments for such neuropathic pain, including neuromodulation. However, rigorous scientific evidence on the usefulness of spinal cord stimulation (SCS) is still scarce. Here, we report the use of high-frequency (10 kHz) SCS (...
journal_title:Journal of pain research
pub_type:
doi:10.2147/JPR.S168031
更新日期:2018-11-27 00:00:00
abstract:OBJECTIVE:To characterize the steady-state pharmacokinetic profile of hydromorphone extended-release (ER) in patients with chronic pain taking concomitant medications. METHODS:This open-label repeat-dose study enrolled 22 patients (mean age, 51.4 years; 81.8% female). All patients were receiving at least one concomita...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S33807
更新日期:2012-01-01 00:00:00