Effects of the glial modulator palmitoylethanolamide on chronic pain intensity and brain function.

abstract：BACKGROUND:Opioid analgesics are effective for postsurgical pain but are associated with opioid-related adverse events, creating a significant clinical and economic burden. Gastrointestinal surgery patients are at high risk for opioid-related adverse events. We conducted a study to assess the impact of an opioid-sparin...

journal_title：Journal of pain research

authors： Marcet JE,Nfonsam VN,Larach S

更新日期：2013-07-18 00:00:00

abstract：Objectives:The primary aim was to assess the psychometric properties (including internal consistency, construct validity, criterion validity, criterion-group validity and responsiveness) of the Fear of Pain Questionnaire (FOPQ) for adolescents (FOPQ-A) and parents (FOPQ-P) translated to Brazilian Portuguese (BrP). The ...

journal_title：Journal of pain research

authors： Berniger Romariz JA,Nonnemacher C,Abreu M,Dickel Segabinazi J,Bandeira JS,Beltran G,Souza A,Torres IL,Caumo W

更新日期：2019-08-07 00:00:00

abstract：BACKGROUND/OBJECTIVE:Previous studies have already reported an independent effect of light-load eccentric exercise (10% eccentric exercise contraction [EEC]) and low-level laser therapy (LLLT) as a protective measure against more strenuous eccentric exercise. However, the difference between these two interventions is l...

journal_title：Journal of pain research

authors： Nausheen S,Moiz JA,Raza S,Shareef MY,Anwer S,Alghadir AH

更新日期：2017-09-11 00:00:00

abstract：:[This corrects the article DOI: 10.2147/JPR.S203721.]. ...

journal_title：Journal of pain research

authors：

更新日期：2020-08-26 00:00:00

abstract：:Purpose: The study aimed to evaluate the analgesic efficiency of dexmedetomidine (DEX) when added to levobupivacaine in continuous ultrasound-guided serratus anterior plane block (SAPB) performed at the end of major thoracic surgery. Methods: This randomized, double-blind trial included 50 adults undergoing thoracic s...

journal_title：Journal of pain research

authors： Abdallah NM,Bakeer AH,Youssef RB,Zaki HV,Abbas DN

更新日期：2019-04-30 00:00:00

abstract：OBJECTIVE:Patients with chronic fatigue syndrome (CFS) complain of long-lasting fatigue and pain which are not relieved by rest and worsened by physical exertion. Previous research has implicated metaboreceptors of muscles to play an important role for chronic fatigue and pain. Therefore, we hypothesized that blocking ...

journal_title：Journal of pain research

authors： Staud R,Kizer T,Robinson ME

更新日期：2017-06-26 00:00:00

abstract：BACKGROUND:Sports-related injuries, such as sprains and strains, commonly occur during exercise and athletic events. Current therapy includes nonsteroidal anti-inflammatory drugs (NSAIDs), which have a high incidence of upper gastrointestinal side effects. The present study assessed the efficacy and safety of the diclo...

journal_title：Journal of pain research

authors： Lionberger DR,Joussellin E,Lanzarotti A,Yanchick J,Magelli M

更新日期：2011-03-07 00:00:00

abstract：Background:Pancreatic cancer is a malignant disease with a high mortality rate and severe pain that is challenging to manage. To reduce the excruciating abdominal pain, opioids and adjuvant agents are conventionally used. Objectives:PRNCPB is a treatment of neural therapy. The number of studies assessing the effect on...

journal_title：Journal of pain research

authors： Molnár I,Hegyi G,Zsom L,Saahs C,Vagedes J,Kapócs G,Kovács Z,Sterner MG,Szőke H

更新日期：2019-01-14 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare the efficacy of percutaneous vertebroplasty (PVP) and interventional tumor removal (ITR), with PVP alone for malignant vertebral compression fractures and/or spinal metastatic tumor with epidural involvement. PATIENTS AND METHODS:A total of 124 patients were selected for ...

journal_title：Journal of pain research

authors： Gu YF,Tian QH,Li YD,Wu CG,Su Y,Song HM,He CJ,Chen D

更新日期：2017-01-20 00:00:00

abstract：:Purpose: Although amiodarone is classified as a Vaughan-Williams class Ⅲ antiarrhythmic drug, it has inhibitory effects on voltage-gated sodium and calcium channels and on β-adrenergic receptors. Given these pharmacological profiles, amiodarone may have analgesic properties. Most patients who are prescribed amiodarone...

journal_title：Journal of pain research

authors： Kotoda M,Ino H,Kumakura Y,Iijima T,Ishiyama T,Matsukawa T

更新日期：2019-06-06 00:00:00

abstract：BACKGROUND:Opioids are the most important pharmacological treatment for moderate-to-severe cancer pain, but side effects limit their use. Transdermal fentanyl (TDF) and oral prolonged-release oxycodone-naloxone (OXN-PR) are effective in controlling chronic pain, with less constipation compared to other opioids. However...

journal_title：Journal of pain research

authors： Roberto A,Greco MT,Legramandi L,Galli F,Galli M,Corli O

更新日期：2017-09-04 00:00:00

abstract：INTRODUCTION:Pain is a common symptom presented in the emergency department (ED) although it is often underestimated, poorly evaluated and treated. The application of a protocol for timely pain management ensured by the nurse can avoid the delays in the analgesic treatment and improve the patient's quality of waiting. ...

journal_title：Journal of pain research

authors： Butti L,Bierti O,Lanfrit R,Bertolini R,Chittaro S,Delli Compagni S,Del Russo D,Mancusi RL,Pertoldi F

更新日期：2017-10-16 00:00:00

abstract：INTRODUCTION:Heat/capsaicin skin sensitization is a well-characterized human experimental model to induce hyperalgesia and allodynia. Using this model, gabapentin, among other drugs, was shown to significantly reduce cutaneous hyperalgesia compared to placebo. Since the larger thermal probes used in the original studie...

journal_title：Journal of pain research

authors： Cavallone LF,Frey K,Montana MC,Joyal J,Regina KJ,Petersen KL,Gereau RW 4th

更新日期：2013-11-07 00:00:00

abstract：Purpose:The aim of this study was to evaluate postoperative discomfort in patients undergoing ambulatory strabismus under general anesthesia, and to identify risk factors associated with the discomfort. Patients and Methods:A cross-sectional study was conducted among 210 consecutive patients undergoing ambulatory stra...

journal_title：Journal of pain research

authors： Huang J,Lin J,Xiong Y,Wang Z,Zhu Y,Ye H,Guo W

更新日期：2020-05-05 00:00:00

abstract：Background:Regional variations of opioid use have been reported from many countries. The objective of this study was to examine opioid prescribing patterns in Germany including low- and high-potency opioids (LPO and HPO) focusing on regional differences. Methods:Data source was the "Information system for health care ...

journal_title：Journal of pain research

authors： Jobski K,Dörks M,Bantel C,Hoffmann F

更新日期：2020-10-07 00:00:00

abstract：BACKGROUND:Low back pain is often called nonspecific pain. In this type of low back pain, various emotions and stress are known to strongly affect pain perception. The purpose of this study is to investigate how the degree of low back pain changes in people with chronic mild low back pain when they are inside and outsi...

journal_title：Journal of pain research

authors： Sakakibara T,Wang Z,Kasai Y

更新日期：2012-01-01 00:00:00

abstract：Background:Millions of people worldwide are suffering from pain. Non-pharmacological therapy has an important role in the treatment of pain and is recognized as a valuable, simple help to lower the dosage of analgesic drugs needed, decreasing the side effects, reducing drug dependency and reducing health care costs; ho...

journal_title：Journal of pain research

authors： Jira L,Weyessa N,Mulatu S,Alemayehu A

更新日期：2020-11-16 00:00:00

abstract：BACKGROUND:It has been demonstrated that N-ethyl-lidocaine (QX-314) can target the transient receptor protein vanilloid 1 (TRPV1) nociceptors when coadministered with capsaicin, resulting in a selective block of the nociceptors. Capsaicin is problematic in therapeutic use because it induces firing of nociceptors. The p...

journal_title：Journal of pain research

authors： Nakagawa H,Hiura A

更新日期：2013-01-01 00:00:00

abstract：Purpose:To identify risk factors for pain after transarterial chemoembolization with drug-eluting beads (DEB-TACE) for hepatocellular carcinoma (HCC). Patients and Methods:In this retrospective study, a total of 118 consecutive patients who underwent DEB-TACE between June 2016 and May 2019 with post-TACE pain were inc...

journal_title：Journal of pain research

authors： Wang TC,Zhang ZS,Xiao YD

更新日期：2020-03-27 00:00:00

abstract：Purpose:Gabapentinoids are currently the mainstay of pharmacological treatments for patients with neuropathic pain. Little is known about the effects of this therapy on the integrity of neuronal networks, especially in patients with an already-damaged nervous system. Since gabapentinoids can worsen cognitive functions ...

journal_title：Journal of pain research

authors： Baldewig M,Goldbaum O,Richter-Landsberg C,Weyland A,Bantel C

更新日期：2018-06-20 00:00:00

abstract：Purpose:The upregulation of spinal NMDA receptor is a crucial mechanism in remifentanil-induced hyperalgesia (RIH). Wnt3a/β-catenin pathway plays an important role in neuropathic pain. We hypothesized that wnt3a inhibitor (iwp-2) could downregulate the expression of NR2B subunit in NMDA receptor, in order to relieve R...

journal_title：Journal of pain research

authors： Gao Y,Zhou S,Pan Y,Gu L,He Y,Sun J

更新日期：2020-05-19 00:00:00

abstract：Background:Low back pain is a prevalent symptom that occurs in all age of people, whereas the pathogenesis is unknown. Iliopsoas tendinopathy is an increasingly recognized hip disorder that may contribute to low back pain. Our purpose is to evaluate the effect of ultrasound-guided local injection of anesthetic and ster...

journal_title：Journal of pain research

authors： Zhu Z,Zhang J,Sheng J,Zhang C,Xie Z

更新日期：2020-11-20 00:00:00

abstract：PURPOSE:Conditioned pain modulation (CPM) is an experimental approach for probing endogenous analgesia by which one painful stimulus (the conditioning stimulus) may inhibit the perceived pain of a subsequent stimulus (the test stimulus). Animal studies suggest that CPM is mediated by a spino-bulbo-spinal loop using obj...

journal_title：Journal of pain research

authors： Bernaba M,Johnson KA,Kong JT,Mackey S

更新日期：2014-11-26 00:00:00

abstract：:Purpose: We aimed to explore the characteristics, and real-life therapeutic management of patients with breakthrough cancer pain (BTcP) caused by bone metastases in Spain, and to evaluate physicians' opinion of and satisfaction with prescribed BTcP therapy. Participants and methods: For the purposes of this study, an ...

journal_title：Journal of pain research

authors： Ferrer Albiach C,Villegas Estévez F,López Alarcón MD,de Madariaga M,Carregal A,Arranz J,Trinidad Martín-Arroyo JM,Jiménez López AJ,Sanz Yagüe A

更新日期：2019-07-12 00:00:00

abstract：:Mechanisms of postherpetic neuralgia (PHN) are still not clear. Transcripts such as microRNA (miRNA) and circular RNA (circRNA) in the affected skin may take part in the initiation and development of this neuropathic pain; however, their expression profiles in skins of PHN patients have not been reported. The PHN affe...

journal_title：Journal of pain research

authors： Cao S,Zhang D,Yuan J,Liu C,Zhou W,Zhang L,Yu S,Qin B,Li Y,Deng W

更新日期：2019-10-16 00:00:00

abstract：:Pain is the most common reason people visit emergency rooms. Pain does not discriminate on the basis of gender, race or age. The state of pain management in the emergency department (ED) is disturbing. ED physicians often do not provide adequate analgesia to their patients, do not meet patients' expectations in treati...

journal_title：Journal of pain research

authors： Motov SM,Khan AN

更新日期：2008-12-09 00:00:00

abstract：:Different pericardial catheters have been suggested as an effective alternative method for drainage of pericardial effusion. The aim of this study was to determine the performance, pain, and quality of life on use of central venous catheter (CVC) for drainage of pericardial effusion in patients undergoing open heart s...

journal_title：Journal of pain research

authors： Ghods K,Razavi MR,Forozeshfard M

更新日期：2016-10-31 00:00:00

abstract：Objectives:Estimate the prevalence of neuropathic pain (NeP) among chronic pain patients attending Brazilian hospitals and pain clinics in São Paulo, Ceara, and Bahia and explore clinical characteristics by subtypes: painful diabetic peripheral neuropathy (pDPN), central neuropathic pain (CNP), chronic low back pain wi...

journal_title：Journal of pain research

authors： Udall M,Kudel I,Cappelleri JC,Sadosky A,King-Concialdi K,Parsons B,Hlavacek P,Hopps M,Salomon PA,DiBonaventura MD,Clark P,Garcia JBS

更新日期：2019-01-07 00:00:00

abstract：Aim:Operant conditioning has long been believed to influence the pain experience through a psychological reward pathway. This study was formulated to test the hypothesis that pain sensitivity may be enhanced >3 months if a monetary reward works as a reinforcement. Methods:Forty healthy subjects volunteered to particip...

journal_title：Journal of pain research

authors： Shiro Y,Ikemoto T,Hayashi K,Arai YC,Deie M,Ueno T

更新日期：2018-10-04 00:00:00

abstract：:Paced breathing has shown efficacy in fibromyalgia (FM), but the mechanisms associated with symptom change are largely unknown. We investigated whether changes in respiratory rate (RR) alone resulted in autonomic changes during normal, paced, and mechanically assisted breathing in untrained FM patients and controls. P...

journal_title：Journal of pain research

authors： Schmidt JE,O'Brien TG,Hooten WM,Joyner MJ,Johnson BD

更新日期：2017-12-08 00:00:00