Abstract:
OBJECTIVE:The aim of this study was to compare the efficacy of percutaneous vertebroplasty (PVP) and interventional tumor removal (ITR), with PVP alone for malignant vertebral compression fractures and/or spinal metastatic tumor with epidural involvement. PATIENTS AND METHODS:A total of 124 patients were selected for PVP and ITR (n = 71, group A) and PVP alone (n = 53, group B). A 14 G needle and guide wire were inserted into the vertebral body, followed by sequential dilatation of the tract until the last cannula reached the anterior portion of the pedicle. Tumors were then ablated with a radiofrequency probe. ITR was performed with marrow nucleus rongeurs, and then cement was injected into the extirpated vertebra. Outcomes were collected preoperatively and at 1, 3 and 6 months and every subsequent 6 months. RESULTS:The rates of pain relief and increased mobility at the last follow-up were higher in group A than those in group B (P < 0.05). There were significant differences in visual analog scale (VAS) score and Oswestry disability index (ODI) score at 1, 3 and 6 months, 1 year and >1 year in group A than in group B (P < 0.05). The rates of paraplegia recovery and vertebral stability in group A were higher than those in group B (P < 0.05). CONCLUSION:PVP and ITR proved to be an effective approach for patients with malignant vertebral compression fractures and/or spinal metastatic tumor and provided distinct advantages in pain relief, function recovery and vertebral stability that are comparable to that obtained with PVP alone.
journal_name
J Pain Resjournal_title
Journal of pain researchauthors
Gu YF,Tian QH,Li YD,Wu CG,Su Y,Song HM,He CJ,Chen Ddoi
10.2147/JPR.S122211subject
Has Abstractpub_date
2017-01-20 00:00:00pages
211-218issn
1178-7090pii
jpr-10-211journal_volume
10pub_type
杂志文章abstract:Introduction:Sickle cell disease (SCD) is an inherited blood disorder characterized by abnormally shaped sickle cells. The hallmark of this disease is intermittent, painful vaso-occlusive episodes (VOE), but a subset of individuals with SCD experience chronic pain. The mechanism of transition to chronic pain is not wel...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S150066
更新日期:2018-02-23 00:00:00
abstract::Osteoarthritis (OA) is a common degenerative disease that affects the vast majority of the elderly and may eventually embark on the road of the total knee arthroplasty (TKA), although controversy still exists in the medical community about the best therapies for osteoarthritis. Compared with physical therapy, oral ana...
journal_title:Journal of pain research
pub_type: 杂志文章,评审
doi:10.2147/JPR.S260878
更新日期:2020-08-04 00:00:00
abstract:Objective:To demonstrate the importance of recognizing and separating nonmedian nerve-related symptoms from those related to median nerve compression at the carpal tunnel. Methods:The records of 80 patients, aged 31-82 years (39 males and 41 females), who had undergone median nerve decompression using open and endosco...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S142153
更新日期:2017-10-24 00:00:00
abstract:Background and Aims:Plantar fasciitis (PF) is the leading cause of heel pain in adults. This study was designed to evaluate the effect of hyaluronic acid (HA) injection in reducing the symptoms of PF, compared with corticosteroid (CS) injection as a conventional treatment. Methods:In this triple-blind, randomized, cli...
journal_title:Journal of pain research
pub_type:
doi:10.2147/JPR.S217419
更新日期:2020-01-14 00:00:00
abstract:INTRODUCTION:Although the majority of opioids in the US are prescribed by nonpain specialists, these providers often report inadequate training in chronic pain management and opioid prescribing. The extent of health care providers' knowledge of opioid prescribing for chronic pain has not been well established. The purp...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S98273
更新日期:2016-03-10 00:00:00
abstract:PURPOSE:The aim of this study was to examine the health and economic burden associated with fibromyalgia among adults in Japan. MATERIALS AND METHODS:Data from the 2011-2014 Japan National Health and Wellness Survey (n=115,271), a nationally representative survey of adults, were analyzed. The greedy matching algorithm...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S110707
更新日期:2016-11-04 00:00:00
abstract:Background:Pain is a common and undertreated non-motor symptom in patients with Parkinson's disease (PD). Opioids have been seldom used in PD because they could worsen cognitive and motor functions. Objective:We aimed to assess efficacy and tolerability of tapentadol in PD patients. Methods:We retrospectively reviewe...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S164939
更新日期:2018-09-13 00:00:00
abstract:BACKGROUND:Opioids and other controlled substances prescribed for chronic pain are associated with abuse, addiction, and death, prompting national initiatives to identify safe and effective pain management strategies including topical analgesics. METHODS:This prospective, observational study evaluated changes from bas...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S143513
更新日期:2017-10-03 00:00:00
abstract::Mechanisms of postherpetic neuralgia (PHN) are still not clear. Transcripts such as microRNA (miRNA) and circular RNA (circRNA) in the affected skin may take part in the initiation and development of this neuropathic pain; however, their expression profiles in skins of PHN patients have not been reported. The PHN affe...
journal_title:Journal of pain research
pub_type:
doi:10.2147/JPR.S221615
更新日期:2019-10-16 00:00:00
abstract::Low back pain in patients with myofascial pain syndrome is characterized by painful active myofascial trigger points (ATPs) in muscles. This article reviews a novel, noninvasive modality that combines simultaneous imaging and treatment, thus taking advantage of the electrodermal information available from imaged ATPs ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S47540
更新日期:2013-06-25 00:00:00
abstract:BACKGROUND:Sports-related injuries, such as sprains and strains, commonly occur during exercise and athletic events. Current therapy includes nonsteroidal anti-inflammatory drugs (NSAIDs), which have a high incidence of upper gastrointestinal side effects. The present study assessed the efficacy and safety of the diclo...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S15380
更新日期:2011-03-07 00:00:00
abstract:Purpose:The upregulation of spinal NMDA receptor is a crucial mechanism in remifentanil-induced hyperalgesia (RIH). Wnt3a/β-catenin pathway plays an important role in neuropathic pain. We hypothesized that wnt3a inhibitor (iwp-2) could downregulate the expression of NR2B subunit in NMDA receptor, in order to relieve R...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S250663
更新日期:2020-05-19 00:00:00
abstract:Purpose:No final conclusion has yet been reached on characteristics of postoperative pain and pain-related factors after video-assisted thoracoscopic surgery (VATS). This study was designed to explore features of acute severe pain and chronic post-surgical pain (CPSP), and the pain-related factors of VATS. Patients an...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S249134
更新日期:2020-07-21 00:00:00
abstract::Cancer and cancer treatment-related chronic pain affect a significant number of patients. The etiology of this pain is diverse and may include nociceptive and/or neuropathic characteristics. Treatment is often multifactorial and may require advanced interventional techniques, such as spinal cord stimulation (SCS). Thi...
journal_title:Journal of pain research
pub_type: 杂志文章,评审
doi:10.2147/JPR.S263857
更新日期:2020-12-07 00:00:00
abstract::Phantom-limb pain (PLP) belongs among difficult-to-treat chronic pain syndromes. Treatment options for PLP are to a large degree implicated by the level of understanding the mechanisms and nature of PLP. Research and clinical findings acknowledge the neuropathic nature of PLP and also suggest that both peripheral as w...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S16733
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Chronic low back pain (CLBP) and chronic neck pain (CNP) have become a serious medical and socioeconomic problem in recent decades. Patients suffering from chronic pain seem to have a higher prevalence of sleep disorders. PURPOSE:To calculate the prevalence of sleep deprivation in patients with CLBP and CNP...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S36386
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:Pain is a common symptom presented in the emergency department (ED) although it is often underestimated, poorly evaluated and treated. The application of a protocol for timely pain management ensured by the nurse can avoid the delays in the analgesic treatment and improve the patient's quality of waiting. ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S138850
更新日期:2017-10-16 00:00:00
abstract::Objectives: To classify patients suffering from low back pain (LBP) into two different groups - patients with lumbar disc herniation (LDH) and patients without this disease based on simple questions and without magnetic resonance imaging (MRI) procedure - and to diagnose the most effective risk factors of LDH. Methods...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S189927
更新日期:2019-04-15 00:00:00
abstract:OBJECTIVE:This systematic review aimed to assess the efficacy, effectiveness, safety, and tolerability of osteopathic manipulative treatment (OMT) in patients with headache. BACKGROUND:Migraine is one of the most common and disabling medical conditions. It affects more than 15% of the general population, causing high ...
journal_title:Journal of pain research
pub_type: 杂志文章,评审
doi:10.2147/JPR.S130501
更新日期:2017-03-14 00:00:00
abstract::Patients with chronic non-malignant pain report impairments of physical, social, and psychological well-being. The goal of pain management should include reducing pain and improving quality of life. Patients with chronic pain require medications that are able to provide adequate pain relief, have minimum dosing interv...
journal_title:Journal of pain research
pub_type: 杂志文章,评审
doi:10.2147/JPR.S49502
更新日期:2014-03-24 00:00:00
abstract::Duloxetine is a serotonin-norepinephrine reuptake inhibitor approved by the US Food and Drug Administration for the treatment of fibromyalgia and painful diabetic neuropathy at doses of 60 mg daily. Duloxetine has been shown to significantly improve the symptoms of chronic pain associated with these disorders, as meas...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S12866
更新日期:2010-12-16 00:00:00
abstract:PURPOSE:Conditioned pain modulation (CPM) is an experimental approach for probing endogenous analgesia by which one painful stimulus (the conditioning stimulus) may inhibit the perceived pain of a subsequent stimulus (the test stimulus). Animal studies suggest that CPM is mediated by a spino-bulbo-spinal loop using obj...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S65607
更新日期:2014-11-26 00:00:00
abstract::Advances in intrathecal analgesia and intrathecal drug delivery systems have allowed for a range of medications to be used in the control of pain and spasticity. This technique allows for reduced medication doses that can decrease the side effects typically associated with oral or parenteral drug delivery. Recent expe...
journal_title:Journal of pain research
pub_type: 杂志文章,评审
doi:10.2147/JPR.S37591
更新日期:2014-11-06 00:00:00
abstract:Background:The ability to accurately diagnose and objectively localize pain generators in chronic pain sufferers remains a major clinical challenge since assessment relies on subjective patient complaints and relatively non-specific diagnostic tools. Developments in clinical molecular imaging, including advances in ima...
journal_title:Journal of pain research
pub_type:
doi:10.2147/JPR.S167839
更新日期:2018-10-12 00:00:00
abstract::Different pericardial catheters have been suggested as an effective alternative method for drainage of pericardial effusion. The aim of this study was to determine the performance, pain, and quality of life on use of central venous catheter (CVC) for drainage of pericardial effusion in patients undergoing open heart s...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S116483
更新日期:2016-10-31 00:00:00
abstract:BACKGROUND/OBJECTIVE:Previous studies have already reported an independent effect of light-load eccentric exercise (10% eccentric exercise contraction [EEC]) and low-level laser therapy (LLLT) as a protective measure against more strenuous eccentric exercise. However, the difference between these two interventions is l...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S139615
更新日期:2017-09-11 00:00:00
abstract:Background:Low back pain is a prevalent symptom that occurs in all age of people, whereas the pathogenesis is unknown. Iliopsoas tendinopathy is an increasingly recognized hip disorder that may contribute to low back pain. Our purpose is to evaluate the effect of ultrasound-guided local injection of anesthetic and ster...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S281880
更新日期:2020-11-20 00:00:00
abstract:Background:Thoracoscopic surgery (TS) has been performed as a minimally invasive procedure since the beginning of the 1990s. This has led to a dramatic change in the postoperative condition of these patients, facilitating early ambulation and easier management of postoperative pain. However, empirical evidence on posto...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S147691
更新日期:2017-11-15 00:00:00
abstract:Background:Postherpetic neuralgia (PHN) refers to pain which remains after the healing of rashes from herpes zoster. Previous literatures have shown that acupuncture has potential benefits for PHN, but evidence remains lacking. Thus, we have performed a systematic review and meta-analysis to identify the effectiveness ...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S199950
更新日期:2019-07-16 00:00:00
abstract:Background:Although the Eph receptor plays an important role in the development of neuropathic pain following nerve injury, there has been no evidence of the participation of the ephrin A4 receptor (EphA4) in the development of trigeminal neuropathic pain. The present study investigated the role of EphA4 in central noc...
journal_title:Journal of pain research
pub_type: 杂志文章
doi:10.2147/JPR.S249185
更新日期:2020-05-22 00:00:00