Spinal N-Cadherin/CREB Signaling Contributes to Chronic Alcohol Consumption-Enhanced Postsurgical Pain.

abstract：Objective:Chronic pain is a highly prevalent and costly condition with few proven treatment options. Since 2014, Geisinger's Department of Pain Medicine has implemented the Multidisciplinary Pain Program (MPP), which consists of a 3-day educational seminar followed by 12 months of comprehensive care. This study examine...

journal_title：Journal of pain research

authors： Maeng DD,Baylor K,Bulger JB,Han JJ

更新日期：2018-10-18 00:00:00

abstract：:Multisite pain, or pain that occurs simultaneously at >1 anatomical site, is more prevalent than single-site pain. While multisite pain affects over half of older adults, it remains an understudied pain entity that may have important functional implications in an aging population. Greater understanding of this complex...

journal_title：Journal of pain research

authors： Butera KA,Roff SR,Buford TW,Cruz-Almeida Y

更新日期：2019-03-29 00:00:00

abstract：Objectives:The primary aim was to assess the psychometric properties (including internal consistency, construct validity, criterion validity, criterion-group validity and responsiveness) of the Fear of Pain Questionnaire (FOPQ) for adolescents (FOPQ-A) and parents (FOPQ-P) translated to Brazilian Portuguese (BrP). The ...

journal_title：Journal of pain research

authors： Berniger Romariz JA,Nonnemacher C,Abreu M,Dickel Segabinazi J,Bandeira JS,Beltran G,Souza A,Torres IL,Caumo W

更新日期：2019-08-07 00:00:00

abstract：Purpose:The aim of this prospective study was to assess the behavior of emergency department (ED) nurses with regard to pain and their role in pain management in a real-life clinical setting. Methods:A total of 509 consecutive patients were enrolled during a 6-week period. A case-report form was used to collect data o...

journal_title：Journal of pain research

authors： Sardo S,Galletta M,Coni E,Aviles Gonzalez CI,Piras I,Pia G,Evangelista M,Musu M,Finco G

更新日期：2020-09-22 00:00:00

abstract：Purpose:Despite the rise in opioid-related hospitalizations, there has been little research regarding opioid-related healthcare utilization. The objective of this study was to estimate the mean adjusted hospital costs, payments, and length of stay (LOS) for opioid-related visits for the nation and each of the nine US c...

journal_title：Journal of pain research

authors： Mallow PJ,Belk KW,Topmiller M,Strassels SA

更新日期：2018-12-04 00:00:00

abstract：:The observation of pain in others may enhance or reduce self-pain, yet the boundary conditions and factors that determine the direction of such effects are poorly understood. The current study set out to show that visual stimulus awareness plays a crucial role in determining whether vicarious pain primarily activates ...

journal_title：Journal of pain research

authors： Terrighena EL,Lu G,Yuen WP,Lee TM,Keuper K

更新日期：2017-07-31 00:00:00

abstract：Background:Although the Eph receptor plays an important role in the development of neuropathic pain following nerve injury, there has been no evidence of the participation of the ephrin A4 receptor (EphA4) in the development of trigeminal neuropathic pain. The present study investigated the role of EphA4 in central noc...

journal_title：Journal of pain research

authors： Kim MJ,Son JY,Ju JS,Ahn DK

更新日期：2020-05-22 00:00:00

abstract：BACKGROUND:In Japan, there are limited options for switching opioid analgesics. Hydromorphone is an opioid analgesic that is routinely used instead of morphine for cancer pain; however, it is not yet available in Japan. The aim of this study was to assess the efficacy and safety of hydromorphone (DS-7113b) extended-rel...

journal_title：Journal of pain research

authors： Inoue S,Saito Y,Tsuneto S,Aruga E,Ide A,Kakurai Y

更新日期：2017-08-18 00:00:00

abstract：:Purpose: The objective for this clinical pilot study was to evaluate changes to chronic pain, vascular health, and inflammatory markers when consuming a dietary supplement blend (DSB, CytoQuel®), containing curcumin, resveratrol, tocotrienols, N-Acetylcysteine, and epigallocatechin gallate. Materials and methods: An o...

journal_title：Journal of pain research

authors： Hamilton DE,Jensen GS

更新日期：2019-05-15 00:00:00

abstract：BACKGROUND:Chronic low back pain (CLBP) and chronic neck pain (CNP) have become a serious medical and socioeconomic problem in recent decades. Patients suffering from chronic pain seem to have a higher prevalence of sleep disorders. PURPOSE:To calculate the prevalence of sleep deprivation in patients with CLBP and CNP...

journal_title：Journal of pain research

authors： Artner J,Cakir B,Spiekermann JA,Kurz S,Leucht F,Reichel H,Lattig F

更新日期：2013-01-01 00:00:00

abstract：Purpose:Pregabalin is indicated for postherpetic neuralgia (PHN) in multiple countries, including China. This analysis compared pregabalin efficacy and safety in Chinese and international patients with PHN. Patients and methods:Data from Chinese and international randomized, double-blind, placebo-controlled trials wer...

journal_title：Journal of pain research

authors： Parsons B,Pan X,Xie L,Chen Y,Ortiz M,Whalen E

更新日期：2018-09-03 00:00:00

abstract：PURPOSE:Conditioned pain modulation (CPM) is an experimental approach for probing endogenous analgesia by which one painful stimulus (the conditioning stimulus) may inhibit the perceived pain of a subsequent stimulus (the test stimulus). Animal studies suggest that CPM is mediated by a spino-bulbo-spinal loop using obj...

journal_title：Journal of pain research

authors： Bernaba M,Johnson KA,Kong JT,Mackey S

更新日期：2014-11-26 00:00:00

abstract：Introduction:Cannabidiol (CBD) is reported to produce pain relief, but the clinically relevant cellular and molecular mechanisms remain uncertain. The TRPV1 receptor integrates noxious stimuli and plays a key role in pain signaling. Hence, we conducted in vitro studies, to elucidate the efficacy and mechanisms of CBD f...

journal_title：Journal of pain research

authors： Anand U,Jones B,Korchev Y,Bloom SR,Pacchetti B,Anand P,Sodergren MH

更新日期：2020-09-11 00:00:00

abstract：BACKGROUND:Several studies have illustrated that multisite pain is more frequent than single pain site, and it is associated with an array of negative consequences. However, there is limited knowledge available about the potential factors associated with multisite pain in the elderly general population. OBJECTIVE:This...

journal_title：Journal of pain research

authors： Dragioti E,Larsson B,Bernfort L,Levin LÅ,Gerdle B

更新日期：2017-08-23 00:00:00

abstract：Purpose:Brachial plexopathy can sometimes cause severe chronic pain. There are many possible treatments for such neuropathic pain, including neuromodulation. However, rigorous scientific evidence on the usefulness of spinal cord stimulation (SCS) is still scarce. Here, we report the use of high-frequency (10 kHz) SCS (...

journal_title：Journal of pain research

authors： Floridia D,Cerra F,Guzzo G,Marino S,Muscarà N,Corallo F,Bramanti A,Chillura A,Naro A

更新日期：2018-11-27 00:00:00

abstract：BACKGROUND:Cutaneous allodynia (CA) is a common feature of migraine, which has a complex underlying pathophysiology that is not well understood. In addition to pain, photophobia, phonophobia, osmophobia, nausea, and vomiting, CA can contribute to the overall disability caused by migraine. The presence of CA can be esta...

journal_title：Journal of pain research

authors： Mathew PG,Cutrer FM,Garza I

更新日期：2016-02-24 00:00:00

abstract：:Purpose: Thirty percent of patients with postherpetic neuralgia (PHN) receiving conservative treatment report unsatisfactory pain relief. Epidural steroid injections (ESIs) are commonly used as a therapeutic intervention in these patients. In this study, we aimed to determine if there are variables that predict the ef...

journal_title：Journal of pain research

authors： Ghanavatian S,Wie CS,Low RS,Butterfield RJ,Zhang N,Dhaliwal GS,Montoya JM,Swanson DL

更新日期：2019-04-23 00:00:00

abstract：:Neuromuscular blockade is a desirable or even essential component of general anesthesia for major surgical operations. As the population continues to age, and more operations are conducted in the elderly, due consideration must be given to neuromuscular blockade in these patients to avoid possible complications. This ...

journal_title：Journal of pain research

authors： Lee LA,Athanassoglou V,Pandit JJ

更新日期：2016-06-17 00:00:00

abstract：:[This corrects the article DOI: 10.2147/JPR.S203721.]. ...

journal_title：Journal of pain research

authors：

更新日期：2020-08-26 00:00:00

abstract：Purpose:The upregulation of spinal NMDA receptor is a crucial mechanism in remifentanil-induced hyperalgesia (RIH). Wnt3a/β-catenin pathway plays an important role in neuropathic pain. We hypothesized that wnt3a inhibitor (iwp-2) could downregulate the expression of NR2B subunit in NMDA receptor, in order to relieve R...

journal_title：Journal of pain research

authors： Gao Y,Zhou S,Pan Y,Gu L,He Y,Sun J

更新日期：2020-05-19 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the safety, tolerability, and preliminary efficacy of NGX-4010, a capsaicin 8% patch, following pretreatment with three different topical anesthetics in patients with peripheral neuropathic pain. METHODS:This open-label, multicenter study enrolled 117 patients with ...

journal_title：Journal of pain research

authors： Webster LR,Peppin JF,Murphy FT,Tobias JK,Vanhove GF

更新日期：2012-01-01 00:00:00

abstract：:Adolescent low back pain (ALBP) is a common form of adolescent morbidity which remains poorly understood. When attempting a meta-analysis of observational studies into ALBP, in an effort to better understand associated risk factors, it is important that the studies involved are homogenic, particularly in terms of the ...

journal_title：Journal of pain research

authors： Milanese S,Grimmer-Somers K

更新日期：2010-05-17 00:00:00

abstract：:Different pericardial catheters have been suggested as an effective alternative method for drainage of pericardial effusion. The aim of this study was to determine the performance, pain, and quality of life on use of central venous catheter (CVC) for drainage of pericardial effusion in patients undergoing open heart s...

journal_title：Journal of pain research

authors： Ghods K,Razavi MR,Forozeshfard M

更新日期：2016-10-31 00:00:00

abstract：Purpose:Post-herpetic neuralgia (PHN) is a common herpes zoster (HZ) complication, where pain persists 90 days after the initial HZ diagnosis. Evaluating PHN risk is essential for determining the burden on patients and health-care systems, but research shows variable estimates. The extent to which these differences are...

journal_title：Journal of pain research

authors： Tanenbaum HC,Lawless A,Sy LS,Hong V,Ackerson B,Bruxvoort K,Luo Y,Tseng HF

更新日期：2020-07-13 00:00:00

abstract：BACKGROUND:Opioid analgesics are effective for postsurgical pain but are associated with opioid-related adverse events, creating a significant clinical and economic burden. Gastrointestinal surgery patients are at high risk for opioid-related adverse events. We conducted a study to assess the impact of an opioid-sparin...

journal_title：Journal of pain research

authors： Marcet JE,Nfonsam VN,Larach S

更新日期：2013-07-18 00:00:00

abstract：Background:It is becoming increasingly important to understand the mechanisms of spinal cord stimulation (SCS) in alleviating neuropathic pain as novel stimulation paradigms arise. Purpose:Additionally, the small anatomic scale of current SCS animal models is a barrier to more translational research. Methods:Using ch...

journal_title：Journal of pain research

authors： Reddy CG,Miller JW,Abode-Iyamah KO,Safayi S,Wilson S,Dalm BD,Fredericks DC,Gillies GT,Howard MA 3rd,Brennan TJ

更新日期：2018-06-15 00:00:00

abstract：Background:The objective of this study was to compare the clinical and radiological outcomes between patients with or without axial symptoms (AS) and investigate the risk factors associated with AS by multivariate regression analysis in anterior cervical discectomy and fusion (ACDF). Materials and methods:The records ...

journal_title：Journal of pain research

authors： Zhou J,Li L,Li T,Xue Y

更新日期：2018-10-26 00:00:00

abstract：:Osteoarthritis (OA) is a common degenerative disease that affects the vast majority of the elderly and may eventually embark on the road of the total knee arthroplasty (TKA), although controversy still exists in the medical community about the best therapies for osteoarthritis. Compared with physical therapy, oral ana...

journal_title：Journal of pain research

authors： Zhang Y,Chen X,Tong Y,Luo J,Bi Q

更新日期：2020-08-04 00:00:00

abstract：Purpose:Gabapentinoids are currently the mainstay of pharmacological treatments for patients with neuropathic pain. Little is known about the effects of this therapy on the integrity of neuronal networks, especially in patients with an already-damaged nervous system. Since gabapentinoids can worsen cognitive functions ...

journal_title：Journal of pain research

authors： Baldewig M,Goldbaum O,Richter-Landsberg C,Weyland A,Bantel C

更新日期：2018-06-20 00:00:00

abstract：Background:Erector spinae plane block (ESPB) as a new trunk fascia block technique was proposed in 2016. ESPB has aroused the interest of many nerve block experts. However, there are few clinical studies on ESPB for lumbar surgery, and its effectiveness and safety are controversial. The goal of this review is to summar...

journal_title：Journal of pain research

authors： Qiu Y,Zhang TJ,Hua Z

更新日期：2020-07-01 00:00:00