Patterns of resistance development with integrase inhibitors in HIV.

abstract：Purpose:Infections, in particular with multidrug-resistant organisms, are a burden for inpatient and outpatient care and the whole community. The pathogens "roam" with patients and their relatives, forming an epidemiological bridge between different care facilities. Patients could play an important role in infection co...

journal_title：Infection and drug resistance

authors： Goerig T,Dittmann K,Kramer A,Diedrich S,Heidecke CD,Huebner NO

更新日期：2018-12-04 00:00:00

abstract：Introduction:Escherichia (E.) coli can cause intestinal and extra-intestinal infections which ranged from mild to life-threatening infections. The severity of infection is a product of many factors including virulence properties and antimicrobial resistance. Objectives:To determine the antibiotic resistance pattern, t...

journal_title：Infection and drug resistance

authors： Abd El-Baky RM,Ibrahim RA,Mohamed DS,Ahmed EF,Hashem ZS

更新日期：2020-04-28 00:00:00

abstract：Background:Pseudomonas aeruginosa is an opportunistic pathogen that causes serious nosocomial infections, especially in immunodeficient patients and cystic fibrosis, cancer, and burned individuals. The biofilm that plays an important role in the virulence of P. aeruginosa is under the regulation of quorum sensing and t...

journal_title：Infection and drug resistance

authors： Sharifian P,Yaslianifard S,Fallah P,Aynesazi S,Bakhtiyari M,Mohammadzadeh M

更新日期：2020-07-21 00:00:00

abstract：Purpose:Plasmids of the incompatibility group X type 3 (IncX3) were described carrying various carbapenemase genes in carbapenemase-producing Enterobacteriaceae (CPE) worldwide and in the United Arab Emirates (UAE), as well. To understand the driving force behind the emergence of such plasmids in the UAE, the relations...

journal_title：Infection and drug resistance

authors： Mouftah SF,Pál T,Darwish D,Ghazawi A,Villa L,Carattoli A,Sonnevend Á

更新日期：2019-06-21 00:00:00

abstract：Introduction:According to our clinical experience, cellulitis is common in summer; however, very few studies have mentioned this trend. Methods:Using Google Trends, we analyzed the monthly data of Google searches for "cellulitis" from 31 countries on 6 continents. Results:Seasonality explained 34%-92% of the variabil...

journal_title：Infection and drug resistance

authors： Zhang X,Dang S,Ji F,Shi J,Li Y,Li M,Jia X,Wan Y,Bao X,Wang W

更新日期：2018-05-03 00:00:00

abstract：Purpose:The aim was to examine the clinical characteristics and risk factors for bloodstream infection (BSI) due to carbapenem-resistant Klebsiella pneumoniae (CRKP) in patients with hematologic malignancies. Materials and Methods:A single-centre, retrospective case-control study representing 734 patients with hematol...

journal_title：Infection and drug resistance

authors： Zhang P,Wang J,Hu H,Zhang S,Wei J,Yang Q,Qu T

更新日期：2020-09-22 00:00:00

abstract：:Raltegravir, an inhibitor of the HIV-1 integrase enzyme, is the first available agent in a new class of antiretroviral drugs. Raltegravir has been studied extensively in clinical trials, and has been well tolerated and highly effective in both treatment-naïve and -experienced patients. Resistance to raltegravir is unu...

journal_title：Infection and drug resistance

authors： Chirch LM,Steigbigel RT

更新日期：2010-01-01 00:00:00

abstract：:While methicillin-resistant Staphylococcus aureus (MRSA) bacteremia has poor outcomes, we describe our experience with Ceftobiprole mainly as a combination therapy for the treatment of MRSA bacteremia. All the cases of MRSA bacteremia in our center at the King Abdulaziz Medical City (KAMC), Riyadh, that had undergone ...

journal_title：Infection and drug resistance

authors： Mahmoud E,Al Mansour S,Bosaeed M,Alharbi A,Alsaedy A,Aljohani S,Alalwan B,Alothman A

更新日期：2020-08-03 00:00:00

abstract：:The rapid detection of carbapenemase allows implementation of infection control measures and adaptation of antibiotic therapy. We evaluated the performances of the Xpert Carba-R V2® assay for the direct detection and identification of carbapenemase on positive blood cultures. We focused our evaluation on its detection...

journal_title：Infection and drug resistance

authors： Cointe A,Walewski V,Hobson CA,Doit C,Bidet P,Dortet L,Bonacorsi S,Birgy A

更新日期：2019-10-23 00:00:00

abstract：:The treatment of urinary tract infections (UTIs) continues to evolve as common uropathogens increasingly become resistant to previously active antimicrobial agents. In addition, bacterial isolates, which were once considered to be either colonizers or contaminants, have emerged as true pathogens, likely related to the...

journal_title：Infection and drug resistance

authors： Bush LM,Chaparro-Rojas F,Okeh V,Etienne J

更新日期：2011-01-01 00:00:00

abstract：:Genetic and cellular studies have shown that the host's innate and adaptive immune responses are an important correlate of viral infection outcome. The features of the host's immune response (host resistance) reflect the coevolution between hosts and pathogens that has occurred over millennia, and that has also result...

journal_title：Infection and drug resistance

authors： Plauzolles A,Lucas M,Gaudieri S

更新日期：2015-04-07 00:00:00

abstract：:Primary infection with human herpesvirus-6 (HHV-6) commonly occurs at an early age in children, most often at 3 years of age, and is associated with childhood diseases, such as exanthema subitum, hepatitis, febrile convulsions, or encephalitis. However, the virus occasionally reactivates from its latent state in immun...

journal_title：Infection and drug resistance

authors： Kuwahara-Ota S,Chinen Y,Mizuno Y,Takimoto-Shimomura T,Matsumura-Kimoto Y,Tanba K,Tsukamoto T,Mizutani S,Shimura Y,Kobayashi T,Horiike S,Kuroda J

更新日期：2018-05-14 00:00:00

abstract：:Removal of the spleen had already been established as a routine technique to treat splenic trauma and other diseases affecting the spleen before the anatomy, physiology, and function of the spleen were known in the mid-twentieth century. It is now widely accepted that the splenectomized individual is at increased risk...

journal_title：Infection and drug resistance

authors： Luu S,Spelman D,Woolley IJ

更新日期：2019-09-12 00:00:00

abstract：:Streptococcus pneumonia is a rare cause of pyogenic sacroiliitis and osteomyelitis. A case of pneumococcal sacroiliitis and osteomyelitis is reported herein. The patient was a previously healthy 54-year-old man with a 3-day history of fever and a 3-week history of increasing right-side thigh pain. Computed tomography ...

journal_title：Infection and drug resistance

authors： Hadano Y,Chang B

更新日期：2018-08-03 00:00:00

abstract：Background:Evidence suggests that genetic variations of exon 1 of mannose-binding lectin 2 (MBL2) may contribute to tuberculosis (TB) risk. Many studies have investigated the association between MBL2 exon 1 polymorphisms (rs1800450, rs1800451, and rs5030737) and TB risk, but yielded inconclusive results. Method:We con...

journal_title：Infection and drug resistance

authors： Wu YJ,Yang X,Chen TD,Zhang ZX,You YZ,Fan ZD

更新日期：2018-08-20 00:00:00

abstract：:Infections by drug-resistant bacteria are life-threatening. As iron is a vital element for the growth of bacteria, iron-chelating agents (siderophores) can be used to arrest their multiplication. Exogenous siderophores - exochelin-MS and deferoxamine-B - were evaluated for their inhibitory activity against methicillin...

journal_title：Infection and drug resistance

authors： Gokarn K,Pal RB

更新日期：2018-01-09 00:00:00

abstract：BACKGROUND:Outpatient parenteral antimicrobial therapy (OPAT) is the administration of intravenous antimicrobial therapy to patients in an outpatient setting. It may be used for patients who have infections that require parenteral treatment but who are otherwise stable enough to not require admission as inpatients. OB...

journal_title：Infection and drug resistance

authors： Al Alawi S,Abdulkarim S,Elhennawy H,Al-Mansoor A,Al Ansari A

更新日期：2015-08-07 00:00:00

abstract：Objective:To genetically characterize clusters of virulence factors (VFs) among extended spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae and assess whether these clusters are associated with genetic determinants or clinical outcomes. Methods:One hundred forty-eight E. coli and 82 K. pn...

journal_title：Infection and drug resistance

authors： Surgers L,Boersma P,Girard PM,Homor A,Geneste D,Arlet G,Decré D,Boyd A

更新日期：2018-12-31 00:00:00

abstract：Background:The aim of this study was to evaluate the clinical performance of the BD Kiestra InoqulA automated specimen processing system with commonly encountered clinical microbiology specimens. Materials and Methods:Four types of clinical specimens (sputum, urine, normally sterile body fluids, and feces) were inocul...

journal_title：Infection and drug resistance

authors： Yue P,Zhou M,Zhang L,Yang Q,Song H,Xu Z,Zhang G,Xie X,Xu Y

更新日期：2020-04-01 00:00:00

abstract：Purpose:The activity of the cationic antimicrobial peptide WLBU2 was evaluated against planktonic cells and biofilms of multi-drug resistant (MDR) Acinetobacter baumannii and Klebsiella pneumoniae, alone and in combination with classical antimicrobial agents. Methods:Control American Type Culture Collection (ATCC) str...

journal_title：Infection and drug resistance

authors： Swedan S,Shubair Z,Almaaytah A

更新日期：2019-07-09 00:00:00

abstract：:COVID-19 is an emerging disease all over the world and spreading at an unpredicted rate, resulting in significant influences on global economies and public health. Clinical, laboratory, and imaging characteristics have been partially described in some observational studies. Not enough systematic reviews on predictors ...

journal_title：Infection and drug resistance

authors： Aly MH,Rahman SS,Ahmed WA,Alghamedi MH,Al Shehri AA,Alkalkami AM,Hassan MH

更新日期：2020-06-26 00:00:00

abstract：:While MIC distributions and percent susceptibility for cefepime and ceftazidime are generally similar among Pseudomonas aeruginosa, we noted an increasing discordance in susceptibility favoring ceftazidime at our hospital. Quantitative reverse transcriptase-polymerase chain reaction was utilized to explore overexpress...

journal_title：Infection and drug resistance

authors： Laohavaleeson S,Lolans K,Quinn JP,Kuti JL,Nicolau DP

更新日期：2008-01-01 00:00:00

abstract：Background:Heteroresistance is a phenomenon that occurs in all bacteria and can cause treatment failure. Yet, the exact mechanisms responsible for heteroresistance still remain unknown. The following study investigated the mechanisms of imipenem-heteroresistance and -resistance in Pseudomonas aeruginosa clinical isolat...

journal_title：Infection and drug resistance

authors： Xu Y,Zheng X,Zeng W,Chen T,Liao W,Qian J,Lin J,Zhou C,Tian X,Cao J,Zhou T

更新日期：2020-05-14 00:00:00

abstract：Background:Raw meat is one of the commonly consumed traditional diets in Ethiopia. However, unhygienic processing and distribution practices are risky for contamination of meat leading to human infection. This study was conducted to assess the presence of multi-drug resistant E. coli with special emphasis on E. coli O1...

journal_title：Infection and drug resistance

authors： Sebsibe MA,Asfaw ET

更新日期：2020-10-27 00:00:00

abstract：Background:Ethiopia is one of the 22 high tuberculosis burden countries. In our country. there are limited published data to show the trend analysis of tuberculosis. Hence, we designed this trend analysis to fill the information gap in our study area. Institutional based retrospective cross-sectional study was employed...

journal_title：Infection and drug resistance

authors： Negash H,Legese H,Adhanom G,Mardu F,Tesfay K,Gebreslasie Gebremeskel S,Berhe B

更新日期：2020-02-24 00:00:00

abstract：Background:In Saudi Arabia, cross-border transmission of multidrug-resistant (MDR) Mycobacterium tuberculosis complex (MTBC) strains might be particularly fostered by high immigration rates. Herein, we aimed to elucidate the transmission dynamics of MDR-MTBC strains and reveal a detailed prediction of all resistance-co...

journal_title：Infection and drug resistance

authors： Al-Ghafli H,Kohl TA,Merker M,Varghese B,Halees A,Niemann S,Al-Hajoj S

更新日期：2018-11-12 00:00:00

abstract：Purpose:Pseudomonas aeruginosa possesses a large number of resistance mechanisms to different antimicrobials with carbapenems being the most powerful in treating resistant P. aeruginosa. Hence, it is imperative to explore different mechanisms of carbapenems-resistance in P. aeruginosa to achieve successful treatment th...

journal_title：Infection and drug resistance

authors： Hassuna NA,Darwish MK,Sayed M,Ibrahem RA

更新日期：2020-01-30 00:00:00

abstract：:Purpose: To investigate antimicrobial resistance and risk factors for mortality of Klebsiella pneumoniae (KP) pneumonia in diabetics and nondiabetics. Patients and methods: A retrospective study was conducted among inpatients of KP pneumonia via electronic medical records in a territory hospital between January 2016 a...

journal_title：Infection and drug resistance

authors： Liu B,Yi H,Fang J,Han L,Zhou M,Guo Y

更新日期：2019-05-07 00:00:00

abstract：Introduction:Trichophyton mentagrophytes and T. interdigitale are important causative agents of superficial mycoses, demonstrating emergent antifungal drug resistance. We studied the antifungal susceptibility profiles in Iranian isolates of these two species. Methods:A total of 96 T. interdigitale and 45 T. mentagroph...

journal_title：Infection and drug resistance

authors： Taghipour S,Shamsizadeh F,Pchelin IM,Rezaei-Matehhkolaei A,Zarei Mahmoudabadi A,Valadan R,Ansari S,Katiraee F,Pakshir K,Zomorodian K,Abastabar M

更新日期：2020-03-13 00:00:00

abstract：Objective:In the present study, we aimed to describe the clinical features, diagnosis, treatment, and prognosis of spinal epidural abscess (SEA). Methods:The complete clinical data of 11 SEA patients who were treated in our hospital system from January 2015 to June 2018 were retrospectively analyzed. Moreover, the cli...

journal_title：Infection and drug resistance

authors： Dai G,Li S,Yin C,Sun Y,Xu D,Wang Z,Luan L,Hou J,Wang T

更新日期：2020-09-29 00:00:00