Molecular epidemiology of ESBL-producing E. coli and K. pneumoniae: establishing virulence clusters.

abstract：:The rapid detection of carbapenemase allows implementation of infection control measures and adaptation of antibiotic therapy. We evaluated the performances of the Xpert Carba-R V2® assay for the direct detection and identification of carbapenemase on positive blood cultures. We focused our evaluation on its detection...

journal_title：Infection and drug resistance

authors： Cointe A,Walewski V,Hobson CA,Doit C,Bidet P,Dortet L,Bonacorsi S,Birgy A

更新日期：2019-10-23 00:00:00

abstract：Introduction:Despite the moderate incidence of tuberculosis (TB) in many parts of Iran, Golestan province had a permanently higher TB incidence rate than the national average. Moreover, Golestan province receives immigrants, mainly from TB-endemic areas of Iran and neighbor countries. Here, we aimed to characterize the...

journal_title：Infection and drug resistance

authors： Mansoori N,Vaziri F,Amini S,Khanipour S,Pourazar Dizaji S,Douraghi M

更新日期：2020-07-01 00:00:00

abstract：Purpose:This study aims to 1) describe the distribution characteristics of teicoplanin trough concentration (Cmin) and explore the related influencing factors and 2) evaluate the nephrotoxicity of teicoplanin in children. Patients and Methods:A cohort of children who were treated with teicoplanin intravenously were in...

journal_title：Infection and drug resistance

authors： Sun D,Zhang T,Mi J,Dong Y,Liu Y,Zhang Y,Zhang D,Wang T,Cheng H,Dong Y

更新日期：2020-11-12 00:00:00

abstract：:Streptococcus pneumonia is a rare cause of pyogenic sacroiliitis and osteomyelitis. A case of pneumococcal sacroiliitis and osteomyelitis is reported herein. The patient was a previously healthy 54-year-old man with a 3-day history of fever and a 3-week history of increasing right-side thigh pain. Computed tomography ...

journal_title：Infection and drug resistance

authors： Hadano Y,Chang B

更新日期：2018-08-03 00:00:00

abstract：Background:Staphylococcus aureus is among the most common causes of health care- and community-associated infections worldwide. The distributions of different S. aureus clones change over time and also vary geographically. The purpose of this study was to determine the molecular type and antimicrobial resistance profil...

journal_title：Infection and drug resistance

authors： Yuan W,Liu J,Zhan Y,Wang L,Jiang Y,Zhang Y,Sun N,Hou N

更新日期：2019-06-20 00:00:00

abstract：Background:Staphylococcus aureus is considered one of the major threats regarding food safety worldwide. Methicillin-resistant S. aureus (MRSA) strains in livestock, companion animals, and wild animals continue to be a potential risk to people working with them. Aim:The current research aims to investigate the potenti...

journal_title：Infection and drug resistance

authors： Hamza DA,Abd-Elsalam RM,Nader SM,Elhariri M,Elhelw R,El-Mahallawy HS

更新日期：2020-06-04 00:00:00

abstract：:A systematic review was conducted to determine the distribution and prevalence of antibiotic-resistant bacteria (ARB), antimicrobial-resistant genes (ARGs), and antimicrobial-resistant gene determinants (ARGDs) in clinical, environmental, and farm settings and to identify key knowledge gaps in a bid to contain their s...

journal_title：Infection and drug resistance

authors： Ekwanzala MD,Dewar JB,Kamika I,Momba MNB

更新日期：2018-10-17 00:00:00

abstract：Background:Infection prevention and control (IPC) is a globally relevant aspect of all health systems impacting the health and safety of both patients and healthcare workers. However, best practices remain a challenge in healthcare delivery especially in resource limited situations. The primary objective of this study ...

journal_title：Infection and drug resistance

authors： Oppong TB,Amponsem-Boateng C,Kyere EKD,Wang Y,Gheisari Z,Oppong EE,Opolot G,Duan G,Yang H

更新日期：2020-11-24 00:00:00

abstract：:Tuberculosis remains the world's second leading infectious cause of death, with nearly one-third of the global population latently infected. Treatment of latent tuberculosis infection is a mainstay of tuberculosis-control efforts in low-to medium-incidence countries. Isoniazid monotherapy has been the standard of care...

journal_title：Infection and drug resistance

authors： Norton BL,Holland DP

更新日期：2012-01-01 00:00:00

abstract：Background:Flomoxef is potentially effective against β-lactamase-producing Enterobacteriaceae because limited clinical data demonstrate its effectiveness against Enterobacteriaceae bloodstream infections (BSIs) based on its minimum inhibitory concentrations (MICs). This study was conducted to determine the optimal brea...

journal_title：Infection and drug resistance

authors： Lee CH,Chen IL,Li CC,Chien CC

更新日期：2018-11-27 00:00:00

abstract：Introduction:Candida species, one among the opportunistic fungi, has become a common pathogen causing vaginal thrush and nosocomial bloodstream infections (BSIs). This study aims to evaluate the prevalence and antifungal susceptibility of various Candida species and slime production by Candida species in BSIs and vulvo...

journal_title：Infection and drug resistance

authors： Tulasidas S,Rao P,Bhat S,Manipura R

更新日期：2018-11-23 00:00:00

abstract：:Aspergillus endocarditis (AE) accounts for a-quarter of all fungal endocarditis, mainly in immunocompromised hosts prior to heart-valve surgery with high mortality, even with treatment. Herein, we report a rare case of AE in a diabetic 60-year-old woman with a history of redo mitral valve prosthesis suspecious of acut...

journal_title：Infection and drug resistance

authors： Jalalian R,Shokohi T,Mirzakhani R,Ghasemian R,Hedayati MT,Ardalani S,Azizi S,Kalhori S,Kermani F,Mayahi S

更新日期：2020-07-10 00:00:00

abstract：BACKGROUND:Biofilm formation inside inserted medical devices leads to their failure and acts as a source of refractory infections. The ultraviolet C (UVC) light is a potential therapy that can be used against the biofilm of bacterial pathogens. OBJECTIVE:We evaluated the efficacy of sublethal dose of UVC light with an...

journal_title：Infection and drug resistance

authors： El-Azizi M,Khardori N

更新日期：2016-08-19 00:00:00

abstract：Introduction:Intravenous (IV) β-lactam antibiotics, excreted through bile into the gastrointestinal (GI) tract, may disrupt the gut microbiome by eliminating the colonization resistance from beneficial bacteria. This increases the risk for Clostridium difficile infection (CDI) and can promote antimicrobial resistance b...

journal_title：Infection and drug resistance

authors： Kokai-Kun JF,Le C,Trout K,Cope JL,Ajami NJ,Degar AJ,Connelly S

更新日期：2020-07-22 00:00:00

abstract：Background:Tachyplesin I is a cationic antimicrobial peptide with a typical cyclic antiparallel β-sheet structure. We previously demonstrated that long-term continuous exposure to increased concentration of tachyplesin I can induce resistant Gram-negative bacteria. However, no significant information is available about...

journal_title：Infection and drug resistance

authors： Hong J,Jiang H,Hu J,Wang L,Liu R

更新日期：2020-01-16 00:00:00

abstract：Purpose:Infections, in particular with multidrug-resistant organisms, are a burden for inpatient and outpatient care and the whole community. The pathogens "roam" with patients and their relatives, forming an epidemiological bridge between different care facilities. Patients could play an important role in infection co...

journal_title：Infection and drug resistance

authors： Goerig T,Dittmann K,Kramer A,Diedrich S,Heidecke CD,Huebner NO

更新日期：2018-12-04 00:00:00

abstract：:The loss of polycationic antimicrobial peptides, polymyxins, due to adhesion to plastics is an important subject matter that influences in vitro susceptibility testing, including minimum inhibitory concentration (MIC) assays. This review reminds us that this issue can serve as a significant source of variation in the ...

journal_title：Infection and drug resistance

authors： Sharafi T,Ardebili A

更新日期：2019-08-27 00:00:00

abstract：:Purpose: The aim of this study was to use a network meta-analysis to evaluate the relative efficacy of various agents at preventing invasive fungal infections (IFIs). In this way, suitable prophylactic regimens may be selected for patients with hematopoietic stem cell transplantation (HSCT). Methods: We conducted a sy...

journal_title：Infection and drug resistance

authors： Su HC,Hua YM,Feng IJ,Wu HC

更新日期：2019-05-15 00:00:00

abstract：Objective:In the present study, we aimed to describe the clinical features, diagnosis, treatment, and prognosis of spinal epidural abscess (SEA). Methods:The complete clinical data of 11 SEA patients who were treated in our hospital system from January 2015 to June 2018 were retrospectively analyzed. Moreover, the cli...

journal_title：Infection and drug resistance

authors： Dai G,Li S,Yin C,Sun Y,Xu D,Wang Z,Luan L,Hou J,Wang T

更新日期：2020-09-29 00:00:00

abstract：Purpose:Pseudomonas aeruginosa possesses a large number of resistance mechanisms to different antimicrobials with carbapenems being the most powerful in treating resistant P. aeruginosa. Hence, it is imperative to explore different mechanisms of carbapenems-resistance in P. aeruginosa to achieve successful treatment th...

journal_title：Infection and drug resistance

authors： Hassuna NA,Darwish MK,Sayed M,Ibrahem RA

更新日期：2020-01-30 00:00:00

abstract：Purpose:The aim was to examine the clinical characteristics and risk factors for bloodstream infection (BSI) due to carbapenem-resistant Klebsiella pneumoniae (CRKP) in patients with hematologic malignancies. Materials and Methods:A single-centre, retrospective case-control study representing 734 patients with hematol...

journal_title：Infection and drug resistance

authors： Zhang P,Wang J,Hu H,Zhang S,Wei J,Yang Q,Qu T

更新日期：2020-09-22 00:00:00

abstract：Background:The aim of this study was to evaluate the clinical performance of the BD Kiestra InoqulA automated specimen processing system with commonly encountered clinical microbiology specimens. Materials and Methods:Four types of clinical specimens (sputum, urine, normally sterile body fluids, and feces) were inocul...

journal_title：Infection and drug resistance

authors： Yue P,Zhou M,Zhang L,Yang Q,Song H,Xu Z,Zhang G,Xie X,Xu Y

更新日期：2020-04-01 00:00:00

abstract：:Rilpivirine is associated with a good efficacy and safety profile. However, data from real-life settings are scarce. Methods:We investigated the durability, safety and efficacy of Rilpivirine-based antiretroviral therapy in a prospective, observational, multicenter study. Results:We enrolled 499 HIV-infected patient...

journal_title：Infection and drug resistance

authors： Bagella P,De Socio GV,Ricci E,Menzaghi B,Martinelli C,Squillace N,Maggi P,Orofino G,Calza L,Carenzi L,Celesia BM,Penco G,Di Biagio A,Valsecchi L,Vichi F,Colombo V,Parruti G,Dentone C,Falasca K,Bonfanti P,Madeddu G

更新日期：2018-04-26 00:00:00

abstract：:Raoultella ornithinolytica is an encapsulated Gram-negative, oxidase-negative, catalase-positive, aerobic, non-motile rod that belongs to the Enterobacteriaceae family. This bacterium was initially classified in the genus Klebsiella as Klebsiella ornithinolytica, until the creation of the genus Raoultella in 2001. R. ...

journal_title：Infection and drug resistance

authors： Hajjar R,Ambaraghassi G,Sebajang H,Schwenter F,Su SH

更新日期：2020-04-15 00:00:00

abstract：Introduction:Management of ventilator-associated pneumonia (VAP), the most common infection in patients on mechanical ventilation, should be tailored to local microbiological data. The aim of this study was to determine susceptibility patterns of organisms causing VAP to develop a treatment algorithm based on these fin...

journal_title：Infection and drug resistance

authors： Awad LS,Abdallah DI,Mugharbil AM,Jisr TH,Droubi NS,El-Rajab NA,Moghnieh RA

更新日期：2017-12-22 00:00:00

abstract：BACKGROUND:Multidrug-resistant tuberculosis (MDR-TB) did not receive major attention until recently in sub-Saharan Africa where the tuberculosis incidence and risk factors are highest. Factors leading to development of drug resistance need to be understood to develop appropriate control strategies for national programs...

journal_title：Infection and drug resistance

authors： Workicho A,Kassahun W,Alemseged F

更新日期：2017-03-13 00:00:00

abstract：Objective:To provide a comprehensive review of vancomycin dosing in patients with hematologic malignancies or neutropenia. Methods:PubMed, Embase and the Cochrane Library were searched through April 2, 2020. Original studies relevant to vancomycin dosing regimen in adults with hematologic malignancies or neutropenia w...

journal_title：Infection and drug resistance

authors： He N,Dong F,Liu W,Zhai S

更新日期：2020-06-16 00:00:00

abstract：:A lung abscess is an infectious pulmonary disease characterized by pus-filled cavity formation and often an air-fluid level. In this article, we described an indolent community-acquired lung abscess suspected as a tumor previously. A 56-year-old male presented with cough and expectoration for 2 months and hemoptysis f...

journal_title：Infection and drug resistance

authors： Guo W,Gao B,Li L,Gai W,Yang J,Zhang Y,Wang L

更新日期：2019-08-08 00:00:00

abstract：Background:China is one of the high-burden countries for multidrug-resistant tuberculosis (MDR-TB), and pyrazinamide is one of the anti-TB drugs used for the shorter MDR-TB treatment regimen. The aim of this study was to determine the correlation between pncA gene mutations and resistance to four first-line anti-TB dru...

journal_title：Infection and drug resistance

authors： Cao Z,Lan Y,Chen L,Xiang M,Peng Z,Zhang J,Zhang H

更新日期：2019-09-30 00:00:00

abstract：:One of the main fundamental mechanisms of antibiotic resistance in Gram-negative bacteria comprises an effective change in the membrane permeability to antibiotics. The Gram-negative bacterial complex cell envelope comprises an outer membrane that delimits the periplasm from the exterior environment. The outer membran...

journal_title：Infection and drug resistance

authors： Ghai I,Ghai S

更新日期：2017-08-30 00:00:00