Resistance To First-Line Antituberculosis Drugs And Prevalence Of pncA Mutations In Clinical Isolates Of Mycobacterium tuberculosis From Zunyi, Guizhou Province Of China.

abstract：Objective:Candida albicans is a yeast with multiple genotypes. It's a commensal fungus colonizing various sites. However, when the host's immune system weakens, it becomes pathogenic and is responsible for various lesions. In Burkina Faso, antifungal drugs are frequently used, particularly fluconazole, the most used sy...

journal_title：Infection and drug resistance

authors： Sawadogo PM,Zida A,Soulama I,Sermé SS,Guiguemdé KT,Junior R,Sangaré I,Bamba S,Ouédraogo-Traoré R,Guiguemdé TR

更新日期：2019-12-16 00:00:00

abstract：Objectives:We investigated the in vitro antimicrobial susceptibilities of clinically important Gram-negative bacteria (GNB) from 16 major teaching hospitals in Taiwan in 2017. Materials and methods:Escherichia coli (n=686) and Klebsiella pneumoniae bloodstream isolates (n=673), non-typhoid Salmonella (NTS; n=221) from...

journal_title：Infection and drug resistance

authors： Jean SS,Lu MC,Shi ZY,Tseng SH,Wu TS,Lu PL,Shao PL,Ko WC,Wang FD,Hsueh PR

更新日期：2018-10-26 00:00:00

abstract：Purpose:Pseudomonas aeruginosa is associated with pulmonary function decline and high disease severity in non-cystic fibrosis (CF) bronchiectasis. The prevalence of nontuberculous mycobacteria (NTM) in non-CF bronchiectasis patients has increased recently. This study investigated the impact of NTM with or without P. ae...

journal_title：Infection and drug resistance

authors： Hsieh MH,Lin CY,Wang CY,Fang YF,Lo YL,Lin SM,Lin HC

更新日期：2018-08-10 00:00:00

abstract：Purpose:With the recommendation of World Health Organization (WHO) and as per the Ethiopian National Implementation Guideline, GeneXpert is used for rapid diagnosis of rifampicin (RIF)-resistant multidrug-resistant tuberculosis (MDR-TB) from the suspected TB patients; however, there were limited findings in Ethiopia pa...

journal_title：Infection and drug resistance

authors： Zewdie O,Dabsu R,Kifle E,Befikadu D

更新日期：2020-10-20 00:00:00

abstract：Aim:Plasmodium falciparum malaria predominantly affects children residing in endemic areas. However, recently a significant number of Malawian adults, who otherwise should have attained some malaria-specific immunity, have been observed to succumb to either uncomplicated malaria (UM) or severe malaria (SM). In addition...

journal_title：Infection and drug resistance

authors： Munyenyembe AU,Gausi K,Hiestand J,Mallewa J,Mandala W

更新日期：2020-01-07 00:00:00

abstract：Background:The prevalence of Helicobacter pylori resistance to metronidazole and clarithromycin is high in Indonesia. Moreover, the increasing levofloxacin resistance rates in the absence of bismuth treatment in Indonesia has led to the use of other antibiotics as alternative regimens. Methods:We determined the minimu...

journal_title：Infection and drug resistance

authors： Miftahussurur M,Waskito LA,Syam AF,Nusi IA,Siregar G,Richardo M,Bakry AF,Rezkitha YAA,Wibawa IDN,Yamaoka Y

更新日期：2019-01-31 00:00:00

abstract：:Vancomycin has usually been associated with nephrotoxicity. Generally, this toxicity is presented as proximal tubular cells injury with or without necrosis and as acute interstitial nephritis. However, development of both lesions is uncommonly described in literature. We present a case of vancomycin-induced nephrotoxi...

journal_title：Infection and drug resistance

authors： Barceló-Vidal J,Rodríguez-García E,Grau S

更新日期：2018-07-30 00:00:00

abstract：Introduction:To achieve target concentrations, the application of higher-than-standard doses of amikacin is proposed for the treatment of sepsis due to an increase in volume of distribution and clearance, but little data are available on aminoglycoside administration in critically ill elderly patients. Patients and me...

journal_title：Infection and drug resistance

authors： Sadeghi K,Hamishehkar H,Najmeddin F,Ahmadi A,Hazrati E,Honarmand H,Mojtahedzadeh M

更新日期：2018-02-13 00:00:00

abstract：Background:Raw meat is one of the commonly consumed traditional diets in Ethiopia. However, unhygienic processing and distribution practices are risky for contamination of meat leading to human infection. This study was conducted to assess the presence of multi-drug resistant E. coli with special emphasis on E. coli O1...

journal_title：Infection and drug resistance

authors： Sebsibe MA,Asfaw ET

更新日期：2020-10-27 00:00:00

abstract：:Purpose: The rapid emergence of multidrug-resistant (MDR) bacteria and the lack of new therapies to eliminate them poses a major threat to global health. With the alarming rise in antimicrobial resistance (AMR), focus has now shifted to the use of the polymyxin class of antibiotics as the last line of defense for trea...

journal_title：Infection and drug resistance

authors： Krishnamurthy M,Lemmon MM,Falcinelli EM,Sandy RA,Dootz JN,Mott TM,Rajamani S,Schaecher KE,Duplantier AJ,Panchal RG

更新日期：2019-05-27 00:00:00

abstract：:Infections by drug-resistant bacteria are life-threatening. As iron is a vital element for the growth of bacteria, iron-chelating agents (siderophores) can be used to arrest their multiplication. Exogenous siderophores - exochelin-MS and deferoxamine-B - were evaluated for their inhibitory activity against methicillin...

journal_title：Infection and drug resistance

authors： Gokarn K,Pal RB

更新日期：2018-01-09 00:00:00

abstract：BACKGROUND:Multidrug-resistant tuberculosis (MDR-TB) did not receive major attention until recently in sub-Saharan Africa where the tuberculosis incidence and risk factors are highest. Factors leading to development of drug resistance need to be understood to develop appropriate control strategies for national programs...

journal_title：Infection and drug resistance

authors： Workicho A,Kassahun W,Alemseged F

更新日期：2017-03-13 00:00:00

abstract：Purpose:The flavohemoprotein (gFlHb) in Giardia plays an important role in managing nitrosative and oxidative stress, and potentially also in virulence and nitroimidazole drug tolerance. The aim of this study was to analyze the genetic diversity of gFlHb in Giardia assemblages A and B clinical isolates. Methods:gFlHb ...

journal_title：Infection and drug resistance

authors： Saghaug CS,Klotz C,Kallio JP,Aebischer T,Langeland N,Hanevik K

更新日期：2020-12-18 00:00:00

abstract：:The rapid detection of carbapenemase allows implementation of infection control measures and adaptation of antibiotic therapy. We evaluated the performances of the Xpert Carba-R V2® assay for the direct detection and identification of carbapenemase on positive blood cultures. We focused our evaluation on its detection...

journal_title：Infection and drug resistance

authors： Cointe A,Walewski V,Hobson CA,Doit C,Bidet P,Dortet L,Bonacorsi S,Birgy A

更新日期：2019-10-23 00:00:00

abstract：Purpose:Plasmids of the incompatibility group X type 3 (IncX3) were described carrying various carbapenemase genes in carbapenemase-producing Enterobacteriaceae (CPE) worldwide and in the United Arab Emirates (UAE), as well. To understand the driving force behind the emergence of such plasmids in the UAE, the relations...

journal_title：Infection and drug resistance

authors： Mouftah SF,Pál T,Darwish D,Ghazawi A,Villa L,Carattoli A,Sonnevend Á

更新日期：2019-06-21 00:00:00

abstract：:Echinocandin antifungal agents have become the first-line therapy for invasive candidiasis (IC) in many countries. Despite their increasing use, resistance to this class of drug is, overall, still uncommon. Here, we report two patients from the People's Republic of China with IC, one with infection caused by pan-echin...

journal_title：Infection and drug resistance

authors： Xiao M,Fan X,Hou X,Chen SC,Wang H,Kong F,Sun ZY,Chu YZ,Xu YC

更新日期：2018-01-23 00:00:00

abstract：:Inorganic polyphosphate (polyP) and its metabolic enzymes are important in several cellular processes related with virulence and antibiotic susceptibility. Accordingly, bacterial polyP synthesis has been proposed as a good target for designing novel antivirulence molecules as alternative to conventional antibiotics. I...

journal_title：Infection and drug resistance

authors： Campos F,Álvarez JA,Ortiz-Severín J,Varas MA,Lagos CF,Cabrera R,Álvarez SA,Chávez FP

更新日期：2019-07-22 00:00:00

abstract：Purpose:This study examined patient- and hospital-level predictor variables that contribute to worse clinical and economic outcomes in patients with carbapenem-nonsusceptible respiratory infections. Patients and Methods:Electronic data (January 2013 to September 2015) were from 78 US hospitals. Nonduplicate, gram-nega...

journal_title：Infection and drug resistance

authors： McCann E,Sung AH,Ye G,Vankeepuram L,Tabak YP

更新日期：2020-03-09 00:00:00

abstract：:[This corrects the article DOI: 10.2147/IDR.S258379.]. ...

journal_title：Infection and drug resistance

authors：

更新日期：2020-09-04 00:00:00

abstract：Purpose:The activity of the cationic antimicrobial peptide WLBU2 was evaluated against planktonic cells and biofilms of multi-drug resistant (MDR) Acinetobacter baumannii and Klebsiella pneumoniae, alone and in combination with classical antimicrobial agents. Methods:Control American Type Culture Collection (ATCC) str...

journal_title：Infection and drug resistance

authors： Swedan S,Shubair Z,Almaaytah A

更新日期：2019-07-09 00:00:00

abstract：Purpose:Pseudomonas aeruginosa possesses a large number of resistance mechanisms to different antimicrobials with carbapenems being the most powerful in treating resistant P. aeruginosa. Hence, it is imperative to explore different mechanisms of carbapenems-resistance in P. aeruginosa to achieve successful treatment th...

journal_title：Infection and drug resistance

authors： Hassuna NA,Darwish MK,Sayed M,Ibrahem RA

更新日期：2020-01-30 00:00:00

abstract：Background:Bloodstream infection (BSI) caused by carbapenem-resistant Enterobacteriaceae are potentially life-threatening related to poorer outcomes. Colistin is considered one of the last-resort treatments against human infections caused by multidrug-resistant (MDR) Gram-negative bacteria. Therefore, emergence of stra...

journal_title：Infection and drug resistance

authors： Lin M,Yang Y,Yang Y,Chen G,He R,Wu Y,Zhong LL,El-Sayed Ahmed MAE,Feng S,Shen C,Wen X,Huang J,Li H,Zheng X,Tian GB

更新日期：2020-05-12 00:00:00

abstract：:While MIC distributions and percent susceptibility for cefepime and ceftazidime are generally similar among Pseudomonas aeruginosa, we noted an increasing discordance in susceptibility favoring ceftazidime at our hospital. Quantitative reverse transcriptase-polymerase chain reaction was utilized to explore overexpress...

journal_title：Infection and drug resistance

authors： Laohavaleeson S,Lolans K,Quinn JP,Kuti JL,Nicolau DP

更新日期：2008-01-01 00:00:00

abstract：Background:Recurrent tuberculosis (TB) following TB treatment completion in HIV-infected individuals remains a major public health burden. We assessed the role of various risk factors in mediating the development of recurrent TB and subsequent resistance to antiretroviral therapy and anti-TB drugs. Patients and method...

journal_title：Infection and drug resistance

authors： Naidoo K,Dookie N,Naidoo K,Yende-Zuma N,Chimukangara B,Bhushan A,Govender D,Gengiah S,Padayatchi N

更新日期：2018-09-05 00:00:00

abstract：:The increase in hospitalization due to acute bacterial skin and skin structure infections (ABSSSI) caused by resistant pathogens supports the need for new treatment options. Antimicrobial options for ABSSSI that provide broad-spectrum coverage, including gram-negative pathogens and multidrug-resistant gram-positive ba...

journal_title：Infection and drug resistance

authors： Righi E,Carnelutti A,Vena A,Bassetti M

更新日期：2018-04-04 00:00:00

abstract：:A lung abscess is an infectious pulmonary disease characterized by pus-filled cavity formation and often an air-fluid level. In this article, we described an indolent community-acquired lung abscess suspected as a tumor previously. A 56-year-old male presented with cough and expectoration for 2 months and hemoptysis f...

journal_title：Infection and drug resistance

authors： Guo W,Gao B,Li L,Gai W,Yang J,Zhang Y,Wang L

更新日期：2019-08-08 00:00:00

abstract：Background:The aim of this study was to evaluate the clinical performance of the BD Kiestra InoqulA automated specimen processing system with commonly encountered clinical microbiology specimens. Materials and Methods:Four types of clinical specimens (sputum, urine, normally sterile body fluids, and feces) were inocul...

journal_title：Infection and drug resistance

authors： Yue P,Zhou M,Zhang L,Yang Q,Song H,Xu Z,Zhang G,Xie X,Xu Y

更新日期：2020-04-01 00:00:00

abstract：:A systematic review was conducted to determine the distribution and prevalence of antibiotic-resistant bacteria (ARB), antimicrobial-resistant genes (ARGs), and antimicrobial-resistant gene determinants (ARGDs) in clinical, environmental, and farm settings and to identify key knowledge gaps in a bid to contain their s...

journal_title：Infection and drug resistance

authors： Ekwanzala MD,Dewar JB,Kamika I,Momba MNB

更新日期：2018-10-17 00:00:00

abstract：:Ceftaroline is an advanced-generation cephalosporin antibiotic recently approved by the US Food and Drug Administration for the treatment of complicated skin and skin-structure infections (cSSSIs). This intravenous broad-spectrum antibiotic exerts potent bactericidal activity by inhibiting bacterial cell wall synthesi...

journal_title：Infection and drug resistance

authors： Hernandez PO,Lema S,Tyring SK,Mendoza N

更新日期：2012-01-01 00:00:00

abstract：:We present here the first report of an OXA-181-producing Klebsiella pneumoniae isolated from the fecal specimen of a patient in China. The OXA-181-encoding gene blaOXA-181 was located on a 51 kb IncX3-type plasmid. Conjugation assay and whole-genome sequencing analysis revealed that this transferrable plasmid in the K...

journal_title：Infection and drug resistance

authors： Liu C,Fang Y,Zeng Y,Lu J,Sun Q,Zhou H,Shen Z,Chen G

更新日期：2020-04-06 00:00:00