Fluorescence enzymatic assay for bacterial polyphosphate kinase 1 (PPK1) as a platform for screening antivirulence molecules.

abstract：Purpose:To develop a rapid EDTA-modified carbapenem inactivation method (reCIM) combined with modified rapid carbapenem inactivation method (mrCIM) to detect carbapenemase and distinguish metallo-β-lactamases from carbapenemases in Enterobacteriaceae in 4 hrs. Materials and Methods:The sensitivities and specificities ...

journal_title：Infection and drug resistance

authors： Wei Q,Sun J,Wang Z,Yan L,Zhang C,Xu X

更新日期：2020-06-23 00:00:00

abstract：Background:The emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) resulted in a worldwide devastating effect with a diagnostic challenge. Identifying risk factors of severity aids in assessment for the need of early hospitalization. We aimed to demonstrate, for the first time, the clinical, laborator...

journal_title：Infection and drug resistance

authors： Ramadan HK,Mahmoud MA,Aburahma MZ,Elkhawaga AA,El-Mokhtar MA,Sayed IM,Hosni A,Hassany SM,Medhat MA

更新日期：2020-10-05 00:00:00

abstract：Background:China is one of the high-burden countries for multidrug-resistant tuberculosis (MDR-TB), and pyrazinamide is one of the anti-TB drugs used for the shorter MDR-TB treatment regimen. The aim of this study was to determine the correlation between pncA gene mutations and resistance to four first-line anti-TB dru...

journal_title：Infection and drug resistance

authors： Cao Z,Lan Y,Chen L,Xiang M,Peng Z,Zhang J,Zhang H

更新日期：2019-09-30 00:00:00

abstract：Objective:The aim of this study was to investigate the in vitro antimicrobial susceptibilities of clinically important Gram-negative bacteria from seven intensive care units in Taiwan in 2016. Materials and methods:In total, 300 non-duplicate isolates of Escherichia coli (n=100), Klebsiella pneumoniae (n=100), and Pse...

journal_title：Infection and drug resistance

authors： Liao CH,Lee NY,Tang HJ,Lee SS,Lin CF,Lu PL,Wu JJ,Ko WC,Lee WS,Hsueh PR

更新日期：2019-03-04 00:00:00

abstract：Objective:Evaluate host and pathogen factors associated with mortality in those with hospital acquired infections (HAI) in a tertiary intensive care unit in Brazil. Methods:Observational and analytical cohort single center study in a general intensive care unit (ICU) in Northeastern Brazil between January 2016 and Aug...

journal_title：Infection and drug resistance

authors： Otero ML,Menezes RC,Ferreira IBB,Issa FL,Agareno G,Carmo TA,Arriaga MB,Fukutani KF,Pamplona Neto L,Agareno S,Filgueiras Filho NM,Akrami KM,Andrade BB

更新日期：2020-08-12 00:00:00

abstract：Purpose:Pseudomonas aeruginosa possesses a large number of resistance mechanisms to different antimicrobials with carbapenems being the most powerful in treating resistant P. aeruginosa. Hence, it is imperative to explore different mechanisms of carbapenems-resistance in P. aeruginosa to achieve successful treatment th...

journal_title：Infection and drug resistance

authors： Hassuna NA,Darwish MK,Sayed M,Ibrahem RA

更新日期：2020-01-30 00:00:00

abstract：:A lung abscess is an infectious pulmonary disease characterized by pus-filled cavity formation and often an air-fluid level. In this article, we described an indolent community-acquired lung abscess suspected as a tumor previously. A 56-year-old male presented with cough and expectoration for 2 months and hemoptysis f...

journal_title：Infection and drug resistance

authors： Guo W,Gao B,Li L,Gai W,Yang J,Zhang Y,Wang L

更新日期：2019-08-08 00:00:00

abstract：Background:The aim of this study was to evaluate the clinical performance of the BD Kiestra InoqulA automated specimen processing system with commonly encountered clinical microbiology specimens. Materials and Methods:Four types of clinical specimens (sputum, urine, normally sterile body fluids, and feces) were inocul...

journal_title：Infection and drug resistance

authors： Yue P,Zhou M,Zhang L,Yang Q,Song H,Xu Z,Zhang G,Xie X,Xu Y

更新日期：2020-04-01 00:00:00

abstract：Aim:Plasmodium falciparum malaria predominantly affects children residing in endemic areas. However, recently a significant number of Malawian adults, who otherwise should have attained some malaria-specific immunity, have been observed to succumb to either uncomplicated malaria (UM) or severe malaria (SM). In addition...

journal_title：Infection and drug resistance

authors： Munyenyembe AU,Gausi K,Hiestand J,Mallewa J,Mandala W

更新日期：2020-01-07 00:00:00

abstract：:COVID-19 is an emerging disease all over the world and spreading at an unpredicted rate, resulting in significant influences on global economies and public health. Clinical, laboratory, and imaging characteristics have been partially described in some observational studies. Not enough systematic reviews on predictors ...

journal_title：Infection and drug resistance

authors： Aly MH,Rahman SS,Ahmed WA,Alghamedi MH,Al Shehri AA,Alkalkami AM,Hassan MH

更新日期：2020-06-26 00:00:00

abstract：Objective:To explore the composition of the ocular microbiome in normal subjects and patients with Meibomian gland dysfunction (MGD). Subjects and methods:Seventy subjects (140 eyes) were enrolled in our study. Signs of dry eye were evaluated and bacterial species in the conjunctival sac (CS) and Meibomian gland (MG) ...

journal_title：Infection and drug resistance

authors： Jiang X,Deng A,Yang J,Bai H,Yang Z,Wu J,Lv H,Li X,Wen T

更新日期：2018-10-11 00:00:00

abstract：Background:Bloodstream infection (BSI) caused by carbapenem-resistant Enterobacteriaceae are potentially life-threatening related to poorer outcomes. Colistin is considered one of the last-resort treatments against human infections caused by multidrug-resistant (MDR) Gram-negative bacteria. Therefore, emergence of stra...

journal_title：Infection and drug resistance

authors： Lin M,Yang Y,Yang Y,Chen G,He R,Wu Y,Zhong LL,El-Sayed Ahmed MAE,Feng S,Shen C,Wen X,Huang J,Li H,Zheng X,Tian GB

更新日期：2020-05-12 00:00:00

abstract：Purpose:The purpose of this study was to identify the common clinical presentations and the evidence on the presence of ageusia and anosmia as an emerging coronavirus disease 2019 (COVID-19) symptom to better inform in both COVID-19 patients and clinicians. Patients and Methods:As part of a double-institutional collab...

journal_title：Infection and drug resistance

authors： Farah Yusuf Mohamud M,Garad Mohamed Y,Mohamed Ali A,Ali Adam B

更新日期：2020-07-29 00:00:00

abstract：BACKGROUND:Lyme disease is a tick-borne illness caused by the spirochete Borrelia burgdorferi. Although antibiotic therapy is usually effective early in the disease, relapse may occur when administration of antibiotics is discontinued. Studies have suggested that resistance and recurrence of Lyme disease might be due t...

journal_title：Infection and drug resistance

authors： Sapi E,Kaur N,Anyanwu S,Luecke DF,Datar A,Patel S,Rossi M,Stricker RB

更新日期：2011-01-01 00:00:00

abstract：Background:Gram-negative bacteria bloodstream infection (GNB-BSI) results in considerable mortality and hospitality costs in cirrhotic patients. β-lactam/β-lactamase inhibitor combinations (BLBLIs) and carbapenems (CARs) are widely recommended for treating GNB-BSI in cirrhotic patients, while the efficacy and cost-effe...

journal_title：Infection and drug resistance

authors： Dong Y,Li Y,Zhang Y,Sun D,Du Q,Zhang T,Teng M,Han R,Wang Y,Zhu L,Lei J,Dong Y,Wang T

更新日期：2020-05-07 00:00:00

abstract：Purpose:To characterize the genetic feature of the carbapenems resistant Acinetobacter johnsonii strain Acsw19 isolated from municipal sludge. This strain was found to carry two copies of blaNDM-1,cmlB1-like gene, and blaOXA-211-like gene along with other 8 antimicrobial resistance genes, 3 plasmids, 15 genomic islands...

journal_title：Infection and drug resistance

authors： Tang L,Shen W,Zhang Z,Zhang J,Wang G,Xiang L,She J,Hu X,Zou G,Zhu B,Zhou Y

更新日期：2020-03-23 00:00:00

abstract：:Removal of the spleen had already been established as a routine technique to treat splenic trauma and other diseases affecting the spleen before the anatomy, physiology, and function of the spleen were known in the mid-twentieth century. It is now widely accepted that the splenectomized individual is at increased risk...

journal_title：Infection and drug resistance

authors： Luu S,Spelman D,Woolley IJ

更新日期：2019-09-12 00:00:00

abstract：:Aspergillus endocarditis (AE) accounts for a-quarter of all fungal endocarditis, mainly in immunocompromised hosts prior to heart-valve surgery with high mortality, even with treatment. Herein, we report a rare case of AE in a diabetic 60-year-old woman with a history of redo mitral valve prosthesis suspecious of acut...

journal_title：Infection and drug resistance

authors： Jalalian R,Shokohi T,Mirzakhani R,Ghasemian R,Hedayati MT,Ardalani S,Azizi S,Kalhori S,Kermani F,Mayahi S

更新日期：2020-07-10 00:00:00

abstract：:The New Delhi Metallo-β-lactamase (NDM) producing Enterobacteriaceae is spreading worldwide. Although the blaNDM gene has been identified in animal associated Enterobacteriaceae isolates in many countries, little is known about its occurrence in animal products in Pakistan. In this study, 13 Escherichia coli isolates ...

journal_title：Infection and drug resistance

authors： Baloch Z,Lv L,Yi L,Wan M,Aslam B,Yang J,Liu JH

更新日期：2019-12-30 00:00:00

abstract：OBJECTIVES:Stenotrophomonas maltophilia shows wide-spectrum resistance to antimicrobials and causes various infections in immunocompromised or critically ill patients with high mortality. In this era of antibiotics resistance, a revival of old antibiotics is now featured. We examined the clinical usefulness of latamoxe...

journal_title：Infection and drug resistance

authors： Hagiya H,Tasaka K,Sendo T,Otsuka F

更新日期：2015-10-20 00:00:00

abstract：Background:Due to increasing colistin usage, the dissemination of the colistin-resistant gene mcr-1 has been increasingly investigated. The aim of this study was to determine whether a traveler on a short-term international trip to a developing country could bring mcr-1 back to their home country. Materials and method...

journal_title：Infection and drug resistance

authors： Nakayama T,Kumeda Y,Kawahara R,Yamaguchi T,Yamamoto Y

更新日期：2018-03-12 00:00:00

abstract：Background:Heteroresistance is a phenomenon that occurs in all bacteria and can cause treatment failure. Yet, the exact mechanisms responsible for heteroresistance still remain unknown. The following study investigated the mechanisms of imipenem-heteroresistance and -resistance in Pseudomonas aeruginosa clinical isolat...

journal_title：Infection and drug resistance

authors： Xu Y,Zheng X,Zeng W,Chen T,Liao W,Qian J,Lin J,Zhou C,Tian X,Cao J,Zhou T

更新日期：2020-05-14 00:00:00

abstract：Purpose:Antifungal resistance and virulence properties of Candida albicans (C. albicans) are growing health problems worldwide. The present study aims to investigate the effect of Zinc Oxide (ZnO) nanoparticles and Nystatin on SAP1-3 genes expression in C. albicans isolates of females with Vulvovaginal Candidiasis (VVC...

journal_title：Infection and drug resistance

authors： Hosseini SS,Joshaghani H,Shokohi T,Ahmadi A,Mehrbakhsh Z

更新日期：2020-02-13 00:00:00

abstract：BACKGROUND:Antimicrobial drug resistance is a global issue that affects health, economic, and social development. The problem has been attributed to misuse of antimicrobial agents. PURPOSE:To identify the agents of bacterial infection in Ghana, determine their antibiogram, and the possibility of setting up a surveilla...

journal_title：Infection and drug resistance

authors： Newman MJ,Frimpong E,Donkor ES,Opintan JA,Asamoah-Adu A

更新日期：2011-01-01 00:00:00

abstract：Objective:To genetically characterize clusters of virulence factors (VFs) among extended spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae and assess whether these clusters are associated with genetic determinants or clinical outcomes. Methods:One hundred forty-eight E. coli and 82 K. pn...

journal_title：Infection and drug resistance

authors： Surgers L,Boersma P,Girard PM,Homor A,Geneste D,Arlet G,Decré D,Boyd A

更新日期：2018-12-31 00:00:00

abstract：Introduction:Trichophyton mentagrophytes and T. interdigitale are important causative agents of superficial mycoses, demonstrating emergent antifungal drug resistance. We studied the antifungal susceptibility profiles in Iranian isolates of these two species. Methods:A total of 96 T. interdigitale and 45 T. mentagroph...

journal_title：Infection and drug resistance

authors： Taghipour S,Shamsizadeh F,Pchelin IM,Rezaei-Matehhkolaei A,Zarei Mahmoudabadi A,Valadan R,Ansari S,Katiraee F,Pakshir K,Zomorodian K,Abastabar M

更新日期：2020-03-13 00:00:00

abstract：Background:Staphylococcus aureus is considered one of the major threats regarding food safety worldwide. Methicillin-resistant S. aureus (MRSA) strains in livestock, companion animals, and wild animals continue to be a potential risk to people working with them. Aim:The current research aims to investigate the potenti...

journal_title：Infection and drug resistance

authors： Hamza DA,Abd-Elsalam RM,Nader SM,Elhariri M,Elhelw R,El-Mahallawy HS

更新日期：2020-06-04 00:00:00

abstract：INTRODUCTION:The characteristics and antimicrobial resistance profiles of Staphylococcus aureus differs according to geographical regions and in relation to antibiotic usage. The aim of this study was to determine the biochemical characteristics of the prevalent S. aureus from Ekiti State, Nigeria, and to evaluate thre...

journal_title：Infection and drug resistance

authors： Olowe OA,Kukoyi OO,Taiwo SS,Ojurongbe O,Opaleye OO,Bolaji OS,Adegoke AA,Makanjuola OB,Ogbolu DO,Alli OT

更新日期：2013-08-20 00:00:00

abstract：:Vancomycin has usually been associated with nephrotoxicity. Generally, this toxicity is presented as proximal tubular cells injury with or without necrosis and as acute interstitial nephritis. However, development of both lesions is uncommonly described in literature. We present a case of vancomycin-induced nephrotoxi...

journal_title：Infection and drug resistance

authors： Barceló-Vidal J,Rodríguez-García E,Grau S

更新日期：2018-07-30 00:00:00

abstract：:Ceftaroline is an advanced-generation cephalosporin antibiotic recently approved by the US Food and Drug Administration for the treatment of complicated skin and skin-structure infections (cSSSIs). This intravenous broad-spectrum antibiotic exerts potent bactericidal activity by inhibiting bacterial cell wall synthesi...

journal_title：Infection and drug resistance

authors： Hernandez PO,Lema S,Tyring SK,Mendoza N

更新日期：2012-01-01 00:00:00