Factors Associated with Mortality in Critically Ill Patients Diagnosed with Hospital Acquired Infections.

abstract：:Genetic and cellular studies have shown that the host's innate and adaptive immune responses are an important correlate of viral infection outcome. The features of the host's immune response (host resistance) reflect the coevolution between hosts and pathogens that has occurred over millennia, and that has also result...

journal_title：Infection and drug resistance

authors： Plauzolles A,Lucas M,Gaudieri S

更新日期：2015-04-07 00:00:00

abstract：Background:Hepatitis E virus (HEV) is an emerging infectious agent that causes acute hepatitis in developing and developed countries. Diagnosis of HEV infection has not been routinely done in Egyptian hospitals, and clinicians do not prescribe ribavirin (RBV) for acute hepatitis cases of unknown etiology (AHUE). We aim...

journal_title：Infection and drug resistance

authors： Sayed IM,El-Mokhtar MA,Mahmoud MAR,Elkhawaga AA,Gaber S,Seddek NH,Abdel-Wahid L,Ashmawy AM,Alkareemy EAR

更新日期：2021-01-12 00:00:00

abstract：BACKGROUND:Biofilm formation inside inserted medical devices leads to their failure and acts as a source of refractory infections. The ultraviolet C (UVC) light is a potential therapy that can be used against the biofilm of bacterial pathogens. OBJECTIVE:We evaluated the efficacy of sublethal dose of UVC light with an...

journal_title：Infection and drug resistance

authors： El-Azizi M,Khardori N

更新日期：2016-08-19 00:00:00

abstract：Purpose:This study examined patient- and hospital-level predictor variables that contribute to worse clinical and economic outcomes in patients with carbapenem-nonsusceptible respiratory infections. Patients and Methods:Electronic data (January 2013 to September 2015) were from 78 US hospitals. Nonduplicate, gram-nega...

journal_title：Infection and drug resistance

authors： McCann E,Sung AH,Ye G,Vankeepuram L,Tabak YP

更新日期：2020-03-09 00:00:00

abstract：Background:Ethiopia is one of the 22 high tuberculosis burden countries. In our country. there are limited published data to show the trend analysis of tuberculosis. Hence, we designed this trend analysis to fill the information gap in our study area. Institutional based retrospective cross-sectional study was employed...

journal_title：Infection and drug resistance

authors： Negash H,Legese H,Adhanom G,Mardu F,Tesfay K,Gebreslasie Gebremeskel S,Berhe B

更新日期：2020-02-24 00:00:00

abstract：:Ceftaroline is an advanced-generation cephalosporin antibiotic recently approved by the US Food and Drug Administration for the treatment of complicated skin and skin-structure infections (cSSSIs). This intravenous broad-spectrum antibiotic exerts potent bactericidal activity by inhibiting bacterial cell wall synthesi...

journal_title：Infection and drug resistance

authors： Hernandez PO,Lema S,Tyring SK,Mendoza N

更新日期：2012-01-01 00:00:00

abstract：Introduction:Helicobacter pylori was discovered first in the stomachs of patients with gastritis and ulcers by Marshall and Warren in 1982. This discovery majorly affected many research areas of gastroenterology. Since then, the main aim has been to eradicate this microaerophilic bacterium from the stomachs of infected...

journal_title：Infection and drug resistance

authors： Khani S,Talebi Bezmin Abadi A,Mohabati Mobarez A

更新日期：2019-11-01 00:00:00

abstract：Introduction:Despite the moderate incidence of tuberculosis (TB) in many parts of Iran, Golestan province had a permanently higher TB incidence rate than the national average. Moreover, Golestan province receives immigrants, mainly from TB-endemic areas of Iran and neighbor countries. Here, we aimed to characterize the...

journal_title：Infection and drug resistance

authors： Mansoori N,Vaziri F,Amini S,Khanipour S,Pourazar Dizaji S,Douraghi M

更新日期：2020-07-01 00:00:00

abstract：:One of the main fundamental mechanisms of antibiotic resistance in Gram-negative bacteria comprises an effective change in the membrane permeability to antibiotics. The Gram-negative bacterial complex cell envelope comprises an outer membrane that delimits the periplasm from the exterior environment. The outer membran...

journal_title：Infection and drug resistance

authors： Ghai I,Ghai S

更新日期：2017-08-30 00:00:00

abstract：Introduction:Trichophyton mentagrophytes and T. interdigitale are important causative agents of superficial mycoses, demonstrating emergent antifungal drug resistance. We studied the antifungal susceptibility profiles in Iranian isolates of these two species. Methods:A total of 96 T. interdigitale and 45 T. mentagroph...

journal_title：Infection and drug resistance

authors： Taghipour S,Shamsizadeh F,Pchelin IM,Rezaei-Matehhkolaei A,Zarei Mahmoudabadi A,Valadan R,Ansari S,Katiraee F,Pakshir K,Zomorodian K,Abastabar M

更新日期：2020-03-13 00:00:00

abstract：Introduction:Surgical site infections (SSIs) are one of the most frequently reported hospital acquired infections associated with significant spread of antibiotic resistance. Purpose:We aimed to evaluate a bundle-based approach in reducing SSI at acute surgical intensive care unit of the Emergency Hospital of Cairo Un...

journal_title：Infection and drug resistance

authors： Wassef M,Mukhtar A,Nabil A,Ezzelarab M,Ghaith D

更新日期：2020-01-28 00:00:00

abstract：Purpose:This research aimed to investigate the antibacterial activity and potential mechanism of luteolin against T. pyogenes. Materials and Methods:The broth microdilution method was used to determine the minimum inhibitory concentrations (MICs) of luteolin against various T. pyogenes strains. The potential mechanism...

journal_title：Infection and drug resistance

authors： Guo Y,Liu Y,Zhang Z,Chen M,Zhang D,Tian C,Liu M,Jiang G

更新日期：2020-06-10 00:00:00

abstract：Background:Heteroresistance is a phenomenon that occurs in all bacteria and can cause treatment failure. Yet, the exact mechanisms responsible for heteroresistance still remain unknown. The following study investigated the mechanisms of imipenem-heteroresistance and -resistance in Pseudomonas aeruginosa clinical isolat...

journal_title：Infection and drug resistance

authors： Xu Y,Zheng X,Zeng W,Chen T,Liao W,Qian J,Lin J,Zhou C,Tian X,Cao J,Zhou T

更新日期：2020-05-14 00:00:00

abstract：Purpose:To investigate the occurrence and genetic characteristics of the blaIMP-26-positive plasmid from a multidrug-resistant clinical isolate, Enterobacter hormaechei L51. Methods:Species identification was determined by MALDI-TOF MS and Sanger sequencing. Antimicrobial susceptibility testing was performed by the ag...

journal_title：Infection and drug resistance

authors： Gou JJ,Liu N,Guo LH,Xu H,Lv T,Yu X,Chen YB,Guo XB,Rao YT,Zheng BW

更新日期：2020-02-20 00:00:00

abstract：:Aspergillus endocarditis (AE) accounts for a-quarter of all fungal endocarditis, mainly in immunocompromised hosts prior to heart-valve surgery with high mortality, even with treatment. Herein, we report a rare case of AE in a diabetic 60-year-old woman with a history of redo mitral valve prosthesis suspecious of acut...

journal_title：Infection and drug resistance

authors： Jalalian R,Shokohi T,Mirzakhani R,Ghasemian R,Hedayati MT,Ardalani S,Azizi S,Kalhori S,Kermani F,Mayahi S

更新日期：2020-07-10 00:00:00

abstract：Background:Bloodstream infection (BSI) caused by carbapenem-resistant Enterobacteriaceae are potentially life-threatening related to poorer outcomes. Colistin is considered one of the last-resort treatments against human infections caused by multidrug-resistant (MDR) Gram-negative bacteria. Therefore, emergence of stra...

journal_title：Infection and drug resistance

authors： Lin M,Yang Y,Yang Y,Chen G,He R,Wu Y,Zhong LL,El-Sayed Ahmed MAE,Feng S,Shen C,Wen X,Huang J,Li H,Zheng X,Tian GB

更新日期：2020-05-12 00:00:00

abstract：OBJECTIVES:Moxifloxacin (MXF) has been advocated for the treatment of extensively drug-resistant (XDR) tuberculosis despite resistance to older-generation fluoroquinolones. We investigated the relationship between the minimum inhibitory concentration (MIC) of MXF and mutations in the gyrA and gyrB genes in Mycobacteriu...

journal_title：Infection and drug resistance

authors： Dookie N,Sturm AW,Moodley P

更新日期：2014-08-19 00:00:00

abstract：Background:Tuberculosis is a communicable disease that is a major cause of ill health, one of the top 10 causes of death worldwide, and the leading cause of death from a single infectious agent, even ranking above human immuno-deficiency virus (HIV/AIDS). Objective:To assess the prevalence and associated risk factor...

journal_title：Infection and drug resistance

authors： Gebretsadik D,Ahmed N,Kebede E,Mohammed M,Belete MA

更新日期：2020-05-21 00:00:00

abstract：BACKGROUND:Lyme disease is a tick-borne illness caused by the spirochete Borrelia burgdorferi. Although antibiotic therapy is usually effective early in the disease, relapse may occur when administration of antibiotics is discontinued. Studies have suggested that resistance and recurrence of Lyme disease might be due t...

journal_title：Infection and drug resistance

authors： Sapi E,Kaur N,Anyanwu S,Luecke DF,Datar A,Patel S,Rossi M,Stricker RB

更新日期：2011-01-01 00:00:00

abstract：:The rapid detection of carbapenemase allows implementation of infection control measures and adaptation of antibiotic therapy. We evaluated the performances of the Xpert Carba-R V2® assay for the direct detection and identification of carbapenemase on positive blood cultures. We focused our evaluation on its detection...

journal_title：Infection and drug resistance

authors： Cointe A,Walewski V,Hobson CA,Doit C,Bidet P,Dortet L,Bonacorsi S,Birgy A

更新日期：2019-10-23 00:00:00

abstract：:Infections by drug-resistant bacteria are life-threatening. As iron is a vital element for the growth of bacteria, iron-chelating agents (siderophores) can be used to arrest their multiplication. Exogenous siderophores - exochelin-MS and deferoxamine-B - were evaluated for their inhibitory activity against methicillin...

journal_title：Infection and drug resistance

authors： Gokarn K,Pal RB

更新日期：2018-01-09 00:00:00

abstract：Backgrounds:The aim of this study was to evaluate both phenotypic and genotypic determinants of mupirocin resistance among methicillin-resistant Staphylococcus aureus (MRSA) and methicillin susceptible S. aureus (MSSA) strains recovered from different clinical samples of children who were admitted to the Children's Med...

journal_title：Infection and drug resistance

authors： Mahmoudi S,Mamishi S,Mohammadi M,Banar M,Ashtiani MTH,Mahzari M,Bahador A,Pourakbari B

更新日期：2019-01-03 00:00:00

abstract：Background:China is one of the high-burden countries for multidrug-resistant tuberculosis (MDR-TB), and pyrazinamide is one of the anti-TB drugs used for the shorter MDR-TB treatment regimen. The aim of this study was to determine the correlation between pncA gene mutations and resistance to four first-line anti-TB dru...

journal_title：Infection and drug resistance

authors： Cao Z,Lan Y,Chen L,Xiang M,Peng Z,Zhang J,Zhang H

更新日期：2019-09-30 00:00:00

abstract：Background:COVID-19 caused by SARS-CoV-2 virus emerged as an unprecedented challenge to discover effective drugs for its prevention and cure. Hyperinflammation-induced lung damage is one of the poor prognostic indicators causing a higher rate of morbidity and mortality of COVID-19 patients. Favipiravir, an antiviral dr...

journal_title：Infection and drug resistance

authors： Kaur RJ,Charan J,Dutta S,Sharma P,Bhardwaj P,Sharma P,Lugova H,Krishnapillai A,Islam S,Haque M,Misra S

更新日期：2020-12-14 00:00:00

abstract：:Purpose: To investigate antimicrobial resistance and risk factors for mortality of Klebsiella pneumoniae (KP) pneumonia in diabetics and nondiabetics. Patients and methods: A retrospective study was conducted among inpatients of KP pneumonia via electronic medical records in a territory hospital between January 2016 a...

journal_title：Infection and drug resistance

authors： Liu B,Yi H,Fang J,Han L,Zhou M,Guo Y

更新日期：2019-05-07 00:00:00

abstract：:Infectious diseases are known as one of the most life-threatening disabilities worldwide. Approximately 13 million deaths related to infectious diseases are reported each year. The only way to combat infectious diseases is by chemotherapy using antimicrobial agents and antibiotics. However, due to uncontrolled and unn...

journal_title：Infection and drug resistance

authors： Allahverdiyev AM,Bagirova M,Abamor ES,Ates SC,Koc RC,Miraloglu M,Elcicek S,Yaman S,Unal G

更新日期：2013-09-18 00:00:00

abstract：Background:Broad-scale evidence has shown the significant association between ambient air pollutants and the development of tuberculosis (TB). However, the impact of air quality on the risk of TB in Taiwan is still poorly understood. Objective:To develop a probabilistic integrated population-level risk assessment appr...

journal_title：Infection and drug resistance

authors： Lin YJ,Lin HC,Yang YF,Chen CY,Ling MP,Chen SC,Chen WY,You SH,Lu TH,Liao CM

更新日期：2019-12-06 00:00:00

abstract：BACKGROUND:Multidrug-resistant tuberculosis (MDR-TB) did not receive major attention until recently in sub-Saharan Africa where the tuberculosis incidence and risk factors are highest. Factors leading to development of drug resistance need to be understood to develop appropriate control strategies for national programs...

journal_title：Infection and drug resistance

authors： Workicho A,Kassahun W,Alemseged F

更新日期：2017-03-13 00:00:00

abstract：:The New Delhi Metallo-β-lactamase (NDM) producing Enterobacteriaceae is spreading worldwide. Although the blaNDM gene has been identified in animal associated Enterobacteriaceae isolates in many countries, little is known about its occurrence in animal products in Pakistan. In this study, 13 Escherichia coli isolates ...

journal_title：Infection and drug resistance

authors： Baloch Z,Lv L,Yi L,Wan M,Aslam B,Yang J,Liu JH

更新日期：2019-12-30 00:00:00

abstract：Background:The timely and accurate diagnosis of infected nonunion is challenging, and there is a need for more efficient biomarkers. Previous studies have shown that fibrinogen plays an important role in mediating inflammation in bacterial infections and, therefore, could be a valuable biomarker for infected nonunion. ...

journal_title：Infection and drug resistance

authors： Wang XJ,Wang Z,Zhang ZT,Qiu XS,Chen M,Chen YX

更新日期：2020-11-04 00:00:00