Resistance to antimicrobial drugs in Ghana.

abstract：BACKGROUND AND AIMS:Resistance mutation analogs to nucleos(t)ides have been described in treatment-naïve patients with chronic hepatitis B (CHB), with clinical implications. The aim of this study was to investigate primary resistance mutations and genotypes circulating in patients naïve to chronic hepatitis B, in the N...

journal_title：Infection and drug resistance

authors： Pacheco SR,Dos Santos MIMA,Stocker A,Zarife MAS,Schinoni MI,Paraná R,Dos Reis MG,Silva LK

更新日期：2017-07-05 00:00:00

abstract：Purpose:Infections, in particular with multidrug-resistant organisms, are a burden for inpatient and outpatient care and the whole community. The pathogens "roam" with patients and their relatives, forming an epidemiological bridge between different care facilities. Patients could play an important role in infection co...

journal_title：Infection and drug resistance

authors： Goerig T,Dittmann K,Kramer A,Diedrich S,Heidecke CD,Huebner NO

更新日期：2018-12-04 00:00:00

abstract：Purpose:This research aimed to investigate the antibacterial activity and potential mechanism of luteolin against T. pyogenes. Materials and Methods:The broth microdilution method was used to determine the minimum inhibitory concentrations (MICs) of luteolin against various T. pyogenes strains. The potential mechanism...

journal_title：Infection and drug resistance

authors： Guo Y,Liu Y,Zhang Z,Chen M,Zhang D,Tian C,Liu M,Jiang G

更新日期：2020-06-10 00:00:00

abstract：Background:Leishmaniasis is an infectious disease common in tropical and subtropical regions caused by the genus Leishmania, which is transmitted by the bite of female sandflies. In this study, we evaluate the anti-leishmanial effect of recombinant Clostridium α-toxin protein alone and the combination with glucantime t...

journal_title：Infection and drug resistance

authors： Namdar F,Khanahmad H,Ghayour Z,Mirzaei F,Namdar A,Aghaei M,Izadi S,Khamesipour F,Hejazi SH

更新日期：2020-07-15 00:00:00

abstract：INTRODUCTION:In recent decades, antimicrobial resistance has become a public health problem, particularly in cases of healthcare-associated infections. Interaction between antibiotic consumption and resistance development is of particular interest regarding Gram-negative bacilli, whose growing resistance has represente...

journal_title：Infection and drug resistance

authors： Oliveira PR,Paula AP,Dal-Paz K,Felix CS,Rossi F,Silva JS,Lima AL

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Outpatient parenteral antimicrobial therapy (OPAT) is the administration of intravenous antimicrobial therapy to patients in an outpatient setting. It may be used for patients who have infections that require parenteral treatment but who are otherwise stable enough to not require admission as inpatients. OB...

journal_title：Infection and drug resistance

authors： Al Alawi S,Abdulkarim S,Elhennawy H,Al-Mansoor A,Al Ansari A

更新日期：2015-08-07 00:00:00

abstract：:Purpose: To investigate antimicrobial resistance and risk factors for mortality of Klebsiella pneumoniae (KP) pneumonia in diabetics and nondiabetics. Patients and methods: A retrospective study was conducted among inpatients of KP pneumonia via electronic medical records in a territory hospital between January 2016 a...

journal_title：Infection and drug resistance

authors： Liu B,Yi H,Fang J,Han L,Zhou M,Guo Y

更新日期：2019-05-07 00:00:00

abstract：Purpose:With the recommendation of World Health Organization (WHO) and as per the Ethiopian National Implementation Guideline, GeneXpert is used for rapid diagnosis of rifampicin (RIF)-resistant multidrug-resistant tuberculosis (MDR-TB) from the suspected TB patients; however, there were limited findings in Ethiopia pa...

journal_title：Infection and drug resistance

authors： Zewdie O,Dabsu R,Kifle E,Befikadu D

更新日期：2020-10-20 00:00:00

abstract：:Aspergillus endocarditis (AE) accounts for a-quarter of all fungal endocarditis, mainly in immunocompromised hosts prior to heart-valve surgery with high mortality, even with treatment. Herein, we report a rare case of AE in a diabetic 60-year-old woman with a history of redo mitral valve prosthesis suspecious of acut...

journal_title：Infection and drug resistance

authors： Jalalian R,Shokohi T,Mirzakhani R,Ghasemian R,Hedayati MT,Ardalani S,Azizi S,Kalhori S,Kermani F,Mayahi S

更新日期：2020-07-10 00:00:00

abstract：Introduction:Klebsiella pneumoniae carbapenemase (KPC) belongs to the Group-A β-lactamases that incorporate serine at their active site and hydrolyze various penicillins, cephalosporins, and carbapenems. Metallo-beta-lactamases (MBLs) are group-B enzymes that contain one or two essential zinc ions in the active sites a...

journal_title：Infection and drug resistance

authors： Urmi UL,Nahar S,Rana M,Sultana F,Jahan N,Hossain B,Alam MS,Mosaddek ASM,McKimm J,Rahman NAA,Islam S,Haque M

更新日期：2020-08-18 00:00:00

abstract：Introduction:Surgical site infections (SSIs) are one of the most frequently reported hospital acquired infections associated with significant spread of antibiotic resistance. Purpose:We aimed to evaluate a bundle-based approach in reducing SSI at acute surgical intensive care unit of the Emergency Hospital of Cairo Un...

journal_title：Infection and drug resistance

authors： Wassef M,Mukhtar A,Nabil A,Ezzelarab M,Ghaith D

更新日期：2020-01-28 00:00:00

abstract：Objective:Evaluate host and pathogen factors associated with mortality in those with hospital acquired infections (HAI) in a tertiary intensive care unit in Brazil. Methods:Observational and analytical cohort single center study in a general intensive care unit (ICU) in Northeastern Brazil between January 2016 and Aug...

journal_title：Infection and drug resistance

authors： Otero ML,Menezes RC,Ferreira IBB,Issa FL,Agareno G,Carmo TA,Arriaga MB,Fukutani KF,Pamplona Neto L,Agareno S,Filgueiras Filho NM,Akrami KM,Andrade BB

更新日期：2020-08-12 00:00:00

abstract：:While methicillin-resistant Staphylococcus aureus (MRSA) bacteremia has poor outcomes, we describe our experience with Ceftobiprole mainly as a combination therapy for the treatment of MRSA bacteremia. All the cases of MRSA bacteremia in our center at the King Abdulaziz Medical City (KAMC), Riyadh, that had undergone ...

journal_title：Infection and drug resistance

authors： Mahmoud E,Al Mansour S,Bosaeed M,Alharbi A,Alsaedy A,Aljohani S,Alalwan B,Alothman A

更新日期：2020-08-03 00:00:00

abstract：:[This corrects the article DOI: 10.2147/IDR.S258379.]. ...

journal_title：Infection and drug resistance

authors：

更新日期：2020-09-04 00:00:00

abstract：Background:Gram-negative bacteria bloodstream infection (GNB-BSI) results in considerable mortality and hospitality costs in cirrhotic patients. β-lactam/β-lactamase inhibitor combinations (BLBLIs) and carbapenems (CARs) are widely recommended for treating GNB-BSI in cirrhotic patients, while the efficacy and cost-effe...

journal_title：Infection and drug resistance

authors： Dong Y,Li Y,Zhang Y,Sun D,Du Q,Zhang T,Teng M,Han R,Wang Y,Zhu L,Lei J,Dong Y,Wang T

更新日期：2020-05-07 00:00:00

abstract：:Genetic and cellular studies have shown that the host's innate and adaptive immune responses are an important correlate of viral infection outcome. The features of the host's immune response (host resistance) reflect the coevolution between hosts and pathogens that has occurred over millennia, and that has also result...

journal_title：Infection and drug resistance

authors： Plauzolles A,Lucas M,Gaudieri S

更新日期：2015-04-07 00:00:00

abstract：Background:Staphylococcus aureus is considered one of the major threats regarding food safety worldwide. Methicillin-resistant S. aureus (MRSA) strains in livestock, companion animals, and wild animals continue to be a potential risk to people working with them. Aim:The current research aims to investigate the potenti...

journal_title：Infection and drug resistance

authors： Hamza DA,Abd-Elsalam RM,Nader SM,Elhariri M,Elhelw R,El-Mahallawy HS

更新日期：2020-06-04 00:00:00

abstract：Purpose:The purpose of this study was to identify the common clinical presentations and the evidence on the presence of ageusia and anosmia as an emerging coronavirus disease 2019 (COVID-19) symptom to better inform in both COVID-19 patients and clinicians. Patients and Methods:As part of a double-institutional collab...

journal_title：Infection and drug resistance

authors： Farah Yusuf Mohamud M,Garad Mohamed Y,Mohamed Ali A,Ali Adam B

更新日期：2020-07-29 00:00:00

abstract：Objectives:We investigated the in vitro antimicrobial susceptibilities of clinically important Gram-negative bacteria (GNB) from 16 major teaching hospitals in Taiwan in 2017. Materials and methods:Escherichia coli (n=686) and Klebsiella pneumoniae bloodstream isolates (n=673), non-typhoid Salmonella (NTS; n=221) from...

journal_title：Infection and drug resistance

authors： Jean SS,Lu MC,Shi ZY,Tseng SH,Wu TS,Lu PL,Shao PL,Ko WC,Wang FD,Hsueh PR

更新日期：2018-10-26 00:00:00

abstract：Background and objective:Acinetobacter baumannii (A. baumannii) is a common nosocomial pathogen, which developed multi-drug-resistance to different classes of antibiotics including carbapenems. This study examined ten common carbapenemase genes among 32 carbapenem-resistant A. baumannii clinical isolates recovered from...

journal_title：Infection and drug resistance

authors： El-Badawy MF,Abdelwahab SF,Alghamdi SA,Shohayeb MM

更新日期：2019-10-03 00:00:00

abstract：Background:Staphylococcus aureus is among the most common causes of health care- and community-associated infections worldwide. The distributions of different S. aureus clones change over time and also vary geographically. The purpose of this study was to determine the molecular type and antimicrobial resistance profil...

journal_title：Infection and drug resistance

authors： Yuan W,Liu J,Zhan Y,Wang L,Jiang Y,Zhang Y,Sun N,Hou N

更新日期：2019-06-20 00:00:00

abstract：:Rilpivirine is associated with a good efficacy and safety profile. However, data from real-life settings are scarce. Methods:We investigated the durability, safety and efficacy of Rilpivirine-based antiretroviral therapy in a prospective, observational, multicenter study. Results:We enrolled 499 HIV-infected patient...

journal_title：Infection and drug resistance

authors： Bagella P,De Socio GV,Ricci E,Menzaghi B,Martinelli C,Squillace N,Maggi P,Orofino G,Calza L,Carenzi L,Celesia BM,Penco G,Di Biagio A,Valsecchi L,Vichi F,Colombo V,Parruti G,Dentone C,Falasca K,Bonfanti P,Madeddu G

更新日期：2018-04-26 00:00:00

abstract：:Inorganic polyphosphate (polyP) and its metabolic enzymes are important in several cellular processes related with virulence and antibiotic susceptibility. Accordingly, bacterial polyP synthesis has been proposed as a good target for designing novel antivirulence molecules as alternative to conventional antibiotics. I...

journal_title：Infection and drug resistance

authors： Campos F,Álvarez JA,Ortiz-Severín J,Varas MA,Lagos CF,Cabrera R,Álvarez SA,Chávez FP

更新日期：2019-07-22 00:00:00

abstract：:The increase in hospitalization due to acute bacterial skin and skin structure infections (ABSSSI) caused by resistant pathogens supports the need for new treatment options. Antimicrobial options for ABSSSI that provide broad-spectrum coverage, including gram-negative pathogens and multidrug-resistant gram-positive ba...

journal_title：Infection and drug resistance

authors： Righi E,Carnelutti A,Vena A,Bassetti M

更新日期：2018-04-04 00:00:00

abstract：Introduction:Helicobacter pylori was discovered first in the stomachs of patients with gastritis and ulcers by Marshall and Warren in 1982. This discovery majorly affected many research areas of gastroenterology. Since then, the main aim has been to eradicate this microaerophilic bacterium from the stomachs of infected...

journal_title：Infection and drug resistance

authors： Khani S,Talebi Bezmin Abadi A,Mohabati Mobarez A

更新日期：2019-11-01 00:00:00

abstract：Purpose:Plasmids of the incompatibility group X type 3 (IncX3) were described carrying various carbapenemase genes in carbapenemase-producing Enterobacteriaceae (CPE) worldwide and in the United Arab Emirates (UAE), as well. To understand the driving force behind the emergence of such plasmids in the UAE, the relations...

journal_title：Infection and drug resistance

authors： Mouftah SF,Pál T,Darwish D,Ghazawi A,Villa L,Carattoli A,Sonnevend Á

更新日期：2019-06-21 00:00:00

abstract：Background:Tuberculosis is a communicable disease that is a major cause of ill health, one of the top 10 causes of death worldwide, and the leading cause of death from a single infectious agent, even ranking above human immuno-deficiency virus (HIV/AIDS). Objective:To assess the prevalence and associated risk factor...

journal_title：Infection and drug resistance

authors： Gebretsadik D,Ahmed N,Kebede E,Mohammed M,Belete MA

更新日期：2020-05-21 00:00:00

abstract：Aim:Plasmodium falciparum malaria predominantly affects children residing in endemic areas. However, recently a significant number of Malawian adults, who otherwise should have attained some malaria-specific immunity, have been observed to succumb to either uncomplicated malaria (UM) or severe malaria (SM). In addition...

journal_title：Infection and drug resistance

authors： Munyenyembe AU,Gausi K,Hiestand J,Mallewa J,Mandala W

更新日期：2020-01-07 00:00:00

abstract：BACKGROUND:Multidrug-resistant tuberculosis (MDR-TB) did not receive major attention until recently in sub-Saharan Africa where the tuberculosis incidence and risk factors are highest. Factors leading to development of drug resistance need to be understood to develop appropriate control strategies for national programs...

journal_title：Infection and drug resistance

authors： Workicho A,Kassahun W,Alemseged F

更新日期：2017-03-13 00:00:00

abstract：Introduction:According to our clinical experience, cellulitis is common in summer; however, very few studies have mentioned this trend. Methods:Using Google Trends, we analyzed the monthly data of Google searches for "cellulitis" from 31 countries on 6 continents. Results:Seasonality explained 34%-92% of the variabil...

journal_title：Infection and drug resistance

authors： Zhang X,Dang S,Ji F,Shi J,Li Y,Li M,Jia X,Wan Y,Bao X,Wang W

更新日期：2018-05-03 00:00:00