Prevalence of Tuberculosis by Automated GeneXpert Rifampicin Assay and Associated Risk Factors Among Presumptive Pulmonary Tuberculosis Patients at Ataye District Hospital, North East Ethiopia.

abstract：Objective:Evaluate host and pathogen factors associated with mortality in those with hospital acquired infections (HAI) in a tertiary intensive care unit in Brazil. Methods:Observational and analytical cohort single center study in a general intensive care unit (ICU) in Northeastern Brazil between January 2016 and Aug...

journal_title：Infection and drug resistance

authors： Otero ML,Menezes RC,Ferreira IBB,Issa FL,Agareno G,Carmo TA,Arriaga MB,Fukutani KF,Pamplona Neto L,Agareno S,Filgueiras Filho NM,Akrami KM,Andrade BB

更新日期：2020-08-12 00:00:00

abstract：Introduction:Candida species, one among the opportunistic fungi, has become a common pathogen causing vaginal thrush and nosocomial bloodstream infections (BSIs). This study aims to evaluate the prevalence and antifungal susceptibility of various Candida species and slime production by Candida species in BSIs and vulvo...

journal_title：Infection and drug resistance

authors： Tulasidas S,Rao P,Bhat S,Manipura R

更新日期：2018-11-23 00:00:00

abstract：Background:China is one of the high-burden countries for multidrug-resistant tuberculosis (MDR-TB), and pyrazinamide is one of the anti-TB drugs used for the shorter MDR-TB treatment regimen. The aim of this study was to determine the correlation between pncA gene mutations and resistance to four first-line anti-TB dru...

journal_title：Infection and drug resistance

authors： Cao Z,Lan Y,Chen L,Xiang M,Peng Z,Zhang J,Zhang H

更新日期：2019-09-30 00:00:00

abstract：:The rapid detection of carbapenemase allows implementation of infection control measures and adaptation of antibiotic therapy. We evaluated the performances of the Xpert Carba-R V2® assay for the direct detection and identification of carbapenemase on positive blood cultures. We focused our evaluation on its detection...

journal_title：Infection and drug resistance

authors： Cointe A,Walewski V,Hobson CA,Doit C,Bidet P,Dortet L,Bonacorsi S,Birgy A

更新日期：2019-10-23 00:00:00

abstract：Background:Colistin acts as the last line of defense against severe infections caused by carbapenem-resistant Enterobacteriaceae. Infections caused by extensively drug-resistant isolates coproducing MCR and carbapenemases have posed a serious public health concern. Purpose:In this study, we reported the first clinical...

journal_title：Infection and drug resistance

authors： Yuan Y,Li Y,Wang G,Li C,Xiang L,She J,Yang Y,Zhong F,Zhang L

更新日期：2019-09-19 00:00:00

abstract：Background:COVID-19 caused by SARS-CoV-2 virus emerged as an unprecedented challenge to discover effective drugs for its prevention and cure. Hyperinflammation-induced lung damage is one of the poor prognostic indicators causing a higher rate of morbidity and mortality of COVID-19 patients. Favipiravir, an antiviral dr...

journal_title：Infection and drug resistance

authors： Kaur RJ,Charan J,Dutta S,Sharma P,Bhardwaj P,Sharma P,Lugova H,Krishnapillai A,Islam S,Haque M,Misra S

更新日期：2020-12-14 00:00:00

abstract：Purpose:Respiratory viruses are important etiologies of community-acquired pneumonia (CAP). However, the impact of different RVs on the outcomes of CAP is not well elucidated. This study aims to compare the clinical features and severity of influenza (Flu-p) and non-influenza respiratory viruses-related pneumonia (NIRV...

journal_title：Infection and drug resistance

authors： Chen L,Han XD,Li YL,Zhang CX,Xing XQ

更新日期：2020-10-08 00:00:00

abstract：Background:Gram-negative bacteria bloodstream infection (GNB-BSI) results in considerable mortality and hospitality costs in cirrhotic patients. β-lactam/β-lactamase inhibitor combinations (BLBLIs) and carbapenems (CARs) are widely recommended for treating GNB-BSI in cirrhotic patients, while the efficacy and cost-effe...

journal_title：Infection and drug resistance

authors： Dong Y,Li Y,Zhang Y,Sun D,Du Q,Zhang T,Teng M,Han R,Wang Y,Zhu L,Lei J,Dong Y,Wang T

更新日期：2020-05-07 00:00:00

abstract：Purpose:Pseudomonas aeruginosa is associated with pulmonary function decline and high disease severity in non-cystic fibrosis (CF) bronchiectasis. The prevalence of nontuberculous mycobacteria (NTM) in non-CF bronchiectasis patients has increased recently. This study investigated the impact of NTM with or without P. ae...

journal_title：Infection and drug resistance

authors： Hsieh MH,Lin CY,Wang CY,Fang YF,Lo YL,Lin SM,Lin HC

更新日期：2018-08-10 00:00:00

abstract：:Raltegravir, an inhibitor of the HIV-1 integrase enzyme, is the first available agent in a new class of antiretroviral drugs. Raltegravir has been studied extensively in clinical trials, and has been well tolerated and highly effective in both treatment-naïve and -experienced patients. Resistance to raltegravir is unu...

journal_title：Infection and drug resistance

authors： Chirch LM,Steigbigel RT

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVES:Stenotrophomonas maltophilia shows wide-spectrum resistance to antimicrobials and causes various infections in immunocompromised or critically ill patients with high mortality. In this era of antibiotics resistance, a revival of old antibiotics is now featured. We examined the clinical usefulness of latamoxe...

journal_title：Infection and drug resistance

authors： Hagiya H,Tasaka K,Sendo T,Otsuka F

更新日期：2015-10-20 00:00:00

abstract：Purpose:Complicated urinary tract infections (cUTIs) are among the most frequent health-care-associated infections. In patients with cUTI, Pseudomonas aeruginosa deserves special attention, since it can affect patients with serious underlying conditions. Our aim was to gain insight into the risk factors and prognosis o...

journal_title：Infection and drug resistance

authors： Gomila A,Carratalà J,Eliakim-Raz N,Shaw E,Wiegand I,Vallejo-Torres L,Gorostiza A,Vigo JM,Morris S,Stoddart M,Grier S,Vank C,Cuperus N,Van den Heuvel L,Vuong C,MacGowan A,Leibovici L,Addy I,Pujol M,COMBACTE MAGNET WP

更新日期：2018-12-18 00:00:00

abstract：Purpose:This study aims to 1) describe the distribution characteristics of teicoplanin trough concentration (Cmin) and explore the related influencing factors and 2) evaluate the nephrotoxicity of teicoplanin in children. Patients and Methods:A cohort of children who were treated with teicoplanin intravenously were in...

journal_title：Infection and drug resistance

authors： Sun D,Zhang T,Mi J,Dong Y,Liu Y,Zhang Y,Zhang D,Wang T,Cheng H,Dong Y

更新日期：2020-11-12 00:00:00

abstract：Background:Infection prevention and control (IPC) is a globally relevant aspect of all health systems impacting the health and safety of both patients and healthcare workers. However, best practices remain a challenge in healthcare delivery especially in resource limited situations. The primary objective of this study ...

journal_title：Infection and drug resistance

authors： Oppong TB,Amponsem-Boateng C,Kyere EKD,Wang Y,Gheisari Z,Oppong EE,Opolot G,Duan G,Yang H

更新日期：2020-11-24 00:00:00

abstract：OBJECTIVE:Many components of the immune system undergo adverse changes during intense physical activity in athletes, leading to a heightened risk of respiratory tract infections. This study evaluated the reduction in infectious processes in athletes due to intensive training with anapsos. METHODS:The study compared at...

journal_title：Infection and drug resistance

authors： Solivellas BM,Martín TC

更新日期：2012-01-01 00:00:00

abstract：:Background: The widespread use of antibiotics has resulted in a high incidence of antibiotic-associated diarrhea (AAD); moreover, the AAD-associated mortality rates have also increased. The effect of combined antibiotic administration on AAD in critically ill patients was analyzed to assist in antibiotic selection for...

journal_title：Infection and drug resistance

authors： Ma H,Zhang L,Zhang Y,Liu Y,He Y,Guo L

更新日期：2019-05-01 00:00:00

abstract：Introduction:Understanding drug resistance is important in drug selection for Helicobacter pylori (H. pylori) eradication, and drug resistance data are lacking in Beijing. Purpose:This cross-sectional study aimed to isolate H. pylori from patients with gastroduodenal diseases and to analyze drug resistance to clarithr...

journal_title：Infection and drug resistance

authors： Lok CH,Zhu D,Wang J,Ren YT,Jiang X,Li SJ,Zhao XY

更新日期：2020-07-06 00:00:00

abstract：:Inorganic polyphosphate (polyP) and its metabolic enzymes are important in several cellular processes related with virulence and antibiotic susceptibility. Accordingly, bacterial polyP synthesis has been proposed as a good target for designing novel antivirulence molecules as alternative to conventional antibiotics. I...

journal_title：Infection and drug resistance

authors： Campos F,Álvarez JA,Ortiz-Severín J,Varas MA,Lagos CF,Cabrera R,Álvarez SA,Chávez FP

更新日期：2019-07-22 00:00:00

abstract：:Lucio's phenomenon (LP) is a special reactional state associated with diffuse multibacillary leprosy; both exhibit a limitative global distribution mainly in Mexico and Central America. We report a case of a 28-year-old female leprosy patient in the People's Republic of China, together with LP and positive anticardiol...

journal_title：Infection and drug resistance

authors： Gao W,Chen Z,Jiang H,Shi Y,Zhang W,Wang H

更新日期：2019-04-02 00:00:00

abstract：Background:Recurrent tuberculosis (TB) following TB treatment completion in HIV-infected individuals remains a major public health burden. We assessed the role of various risk factors in mediating the development of recurrent TB and subsequent resistance to antiretroviral therapy and anti-TB drugs. Patients and method...

journal_title：Infection and drug resistance

authors： Naidoo K,Dookie N,Naidoo K,Yende-Zuma N,Chimukangara B,Bhushan A,Govender D,Gengiah S,Padayatchi N

更新日期：2018-09-05 00:00:00

abstract：:Mycoplasma genitalium is one of the important causes of non-gonococcal urethritis. Rising incidence and emerging antimicrobial resistance are a major concern these days. The poor clinical outcomes with doxycycline therapy led to the use of azithromycin as the primary drug of choice. Single-dose azithromycin regimen ov...

journal_title：Infection and drug resistance

authors： Sethi S,Zaman K,Jain N

更新日期：2017-09-01 00:00:00

abstract：Purpose:The aim of this work was to identify a novel β-lactamase gene blaPAU-1 encoded on the plasmid of a clinical Pseudomonas aeruginosa isolate. Materials and methods:The clinical P. aeruginosa isolates were isolated from a hospital in southern China. Molecular cloning was performed to analyze the function of the r...

journal_title：Infection and drug resistance

authors： Wang J,Xu T,Ying J,Zhou W,Chen Q,Qian C,Zhu X,Shen K,Li P,Li K,Bao Q,Lu J

更新日期：2019-12-05 00:00:00

abstract：Purpose:Infections, in particular with multidrug-resistant organisms, are a burden for inpatient and outpatient care and the whole community. The pathogens "roam" with patients and their relatives, forming an epidemiological bridge between different care facilities. Patients could play an important role in infection co...

journal_title：Infection and drug resistance

authors： Goerig T,Dittmann K,Kramer A,Diedrich S,Heidecke CD,Huebner NO

更新日期：2018-12-04 00:00:00

abstract：OBJECTIVES:Moxifloxacin (MXF) has been advocated for the treatment of extensively drug-resistant (XDR) tuberculosis despite resistance to older-generation fluoroquinolones. We investigated the relationship between the minimum inhibitory concentration (MIC) of MXF and mutations in the gyrA and gyrB genes in Mycobacteriu...

journal_title：Infection and drug resistance

authors： Dookie N,Sturm AW,Moodley P

更新日期：2014-08-19 00:00:00

abstract：Background:Neonatal sepsis (NS) is one of the leading causes of infant morbidity and mortality, but little is known about pathogen incidence and distribution in China. Methods:In this retrospective study (January 2012 to December 2016), culture-proven cases aged less than 28 days with diagnosed NS in the Guangzhou Wom...

journal_title：Infection and drug resistance

authors： Gao K,Fu J,Guan X,Zhu S,Zeng L,Xu X,Chang CY,Liu H

更新日期：2019-12-03 00:00:00

abstract：:Primary infection with human herpesvirus-6 (HHV-6) commonly occurs at an early age in children, most often at 3 years of age, and is associated with childhood diseases, such as exanthema subitum, hepatitis, febrile convulsions, or encephalitis. However, the virus occasionally reactivates from its latent state in immun...

journal_title：Infection and drug resistance

authors： Kuwahara-Ota S,Chinen Y,Mizuno Y,Takimoto-Shimomura T,Matsumura-Kimoto Y,Tanba K,Tsukamoto T,Mizutani S,Shimura Y,Kobayashi T,Horiike S,Kuroda J

更新日期：2018-05-14 00:00:00

abstract：BACKGROUND:Multidrug-resistant tuberculosis (MDR-TB) did not receive major attention until recently in sub-Saharan Africa where the tuberculosis incidence and risk factors are highest. Factors leading to development of drug resistance need to be understood to develop appropriate control strategies for national programs...

journal_title：Infection and drug resistance

authors： Workicho A,Kassahun W,Alemseged F

更新日期：2017-03-13 00:00:00

abstract：:Streptococcus pneumonia is a rare cause of pyogenic sacroiliitis and osteomyelitis. A case of pneumococcal sacroiliitis and osteomyelitis is reported herein. The patient was a previously healthy 54-year-old man with a 3-day history of fever and a 3-week history of increasing right-side thigh pain. Computed tomography ...

journal_title：Infection and drug resistance

authors： Hadano Y,Chang B

更新日期：2018-08-03 00:00:00

abstract：:While MIC distributions and percent susceptibility for cefepime and ceftazidime are generally similar among Pseudomonas aeruginosa, we noted an increasing discordance in susceptibility favoring ceftazidime at our hospital. Quantitative reverse transcriptase-polymerase chain reaction was utilized to explore overexpress...

journal_title：Infection and drug resistance

authors： Laohavaleeson S,Lolans K,Quinn JP,Kuti JL,Nicolau DP

更新日期：2008-01-01 00:00:00

abstract：Background:Broad-scale evidence has shown the significant association between ambient air pollutants and the development of tuberculosis (TB). However, the impact of air quality on the risk of TB in Taiwan is still poorly understood. Objective:To develop a probabilistic integrated population-level risk assessment appr...

journal_title：Infection and drug resistance

authors： Lin YJ,Lin HC,Yang YF,Chen CY,Ling MP,Chen SC,Chen WY,You SH,Lu TH,Liao CM

更新日期：2019-12-06 00:00:00