Genotypic to Phenotypic Resistance Discrepancies Identified Involving β-Lactamase Genes, blaKPC, blaIMP, blaNDM-1, and blaVIM in Uropathogenic Klebsiella pneumoniae.

abstract：Background:The prevalence of Helicobacter pylori resistance to metronidazole and clarithromycin is high in Indonesia. Moreover, the increasing levofloxacin resistance rates in the absence of bismuth treatment in Indonesia has led to the use of other antibiotics as alternative regimens. Methods:We determined the minimu...

journal_title：Infection and drug resistance

authors： Miftahussurur M,Waskito LA,Syam AF,Nusi IA,Siregar G,Richardo M,Bakry AF,Rezkitha YAA,Wibawa IDN,Yamaoka Y

更新日期：2019-01-31 00:00:00

abstract：:Genetic and cellular studies have shown that the host's innate and adaptive immune responses are an important correlate of viral infection outcome. The features of the host's immune response (host resistance) reflect the coevolution between hosts and pathogens that has occurred over millennia, and that has also result...

journal_title：Infection and drug resistance

authors： Plauzolles A,Lucas M,Gaudieri S

更新日期：2015-04-07 00:00:00

abstract：:Rilpivirine is associated with a good efficacy and safety profile. However, data from real-life settings are scarce. Methods:We investigated the durability, safety and efficacy of Rilpivirine-based antiretroviral therapy in a prospective, observational, multicenter study. Results:We enrolled 499 HIV-infected patient...

journal_title：Infection and drug resistance

authors： Bagella P,De Socio GV,Ricci E,Menzaghi B,Martinelli C,Squillace N,Maggi P,Orofino G,Calza L,Carenzi L,Celesia BM,Penco G,Di Biagio A,Valsecchi L,Vichi F,Colombo V,Parruti G,Dentone C,Falasca K,Bonfanti P,Madeddu G

更新日期：2018-04-26 00:00:00

abstract：:Inorganic polyphosphate (polyP) and its metabolic enzymes are important in several cellular processes related with virulence and antibiotic susceptibility. Accordingly, bacterial polyP synthesis has been proposed as a good target for designing novel antivirulence molecules as alternative to conventional antibiotics. I...

journal_title：Infection and drug resistance

authors： Campos F,Álvarez JA,Ortiz-Severín J,Varas MA,Lagos CF,Cabrera R,Álvarez SA,Chávez FP

更新日期：2019-07-22 00:00:00

abstract：Introduction:Understanding drug resistance is important in drug selection for Helicobacter pylori (H. pylori) eradication, and drug resistance data are lacking in Beijing. Purpose:This cross-sectional study aimed to isolate H. pylori from patients with gastroduodenal diseases and to analyze drug resistance to clarithr...

journal_title：Infection and drug resistance

authors： Lok CH,Zhu D,Wang J,Ren YT,Jiang X,Li SJ,Zhao XY

更新日期：2020-07-06 00:00:00

abstract：Introduction:Escherichia (E.) coli can cause intestinal and extra-intestinal infections which ranged from mild to life-threatening infections. The severity of infection is a product of many factors including virulence properties and antimicrobial resistance. Objectives:To determine the antibiotic resistance pattern, t...

journal_title：Infection and drug resistance

authors： Abd El-Baky RM,Ibrahim RA,Mohamed DS,Ahmed EF,Hashem ZS

更新日期：2020-04-28 00:00:00

abstract：Purpose:Pseudomonas aeruginosa possesses a large number of resistance mechanisms to different antimicrobials with carbapenems being the most powerful in treating resistant P. aeruginosa. Hence, it is imperative to explore different mechanisms of carbapenems-resistance in P. aeruginosa to achieve successful treatment th...

journal_title：Infection and drug resistance

authors： Hassuna NA,Darwish MK,Sayed M,Ibrahem RA

更新日期：2020-01-30 00:00:00

abstract：Background:The aim of this study was to evaluate the clinical performance of the BD Kiestra InoqulA automated specimen processing system with commonly encountered clinical microbiology specimens. Materials and Methods:Four types of clinical specimens (sputum, urine, normally sterile body fluids, and feces) were inocul...

journal_title：Infection and drug resistance

authors： Yue P,Zhou M,Zhang L,Yang Q,Song H,Xu Z,Zhang G,Xie X,Xu Y

更新日期：2020-04-01 00:00:00

abstract：Purpose:The aim of this work was to identify a novel β-lactamase gene blaPAU-1 encoded on the plasmid of a clinical Pseudomonas aeruginosa isolate. Materials and methods:The clinical P. aeruginosa isolates were isolated from a hospital in southern China. Molecular cloning was performed to analyze the function of the r...

journal_title：Infection and drug resistance

authors： Wang J,Xu T,Ying J,Zhou W,Chen Q,Qian C,Zhu X,Shen K,Li P,Li K,Bao Q,Lu J

更新日期：2019-12-05 00:00:00

abstract：Purpose:The problem of carbapenem-resistant Pseudomonas aeruginosa in health-care settings is growing worse. This study was conducted to investigate the rate of carbapenemase genes, antibiotic resistance, and virulence factors in carbapenem-resistant P. aeruginosa associated with hospital-acquired infections. Patients...

journal_title：Infection and drug resistance

authors： El-Mahdy R,El-Kannishy G

更新日期：2019-11-07 00:00:00

abstract：Introduction:Helicobacter pylori was discovered first in the stomachs of patients with gastritis and ulcers by Marshall and Warren in 1982. This discovery majorly affected many research areas of gastroenterology. Since then, the main aim has been to eradicate this microaerophilic bacterium from the stomachs of infected...

journal_title：Infection and drug resistance

authors： Khani S,Talebi Bezmin Abadi A,Mohabati Mobarez A

更新日期：2019-11-01 00:00:00

abstract：:Aspergillus endocarditis (AE) accounts for a-quarter of all fungal endocarditis, mainly in immunocompromised hosts prior to heart-valve surgery with high mortality, even with treatment. Herein, we report a rare case of AE in a diabetic 60-year-old woman with a history of redo mitral valve prosthesis suspecious of acut...

journal_title：Infection and drug resistance

authors： Jalalian R,Shokohi T,Mirzakhani R,Ghasemian R,Hedayati MT,Ardalani S,Azizi S,Kalhori S,Kermani F,Mayahi S

更新日期：2020-07-10 00:00:00

abstract：:A lung abscess is an infectious pulmonary disease characterized by pus-filled cavity formation and often an air-fluid level. In this article, we described an indolent community-acquired lung abscess suspected as a tumor previously. A 56-year-old male presented with cough and expectoration for 2 months and hemoptysis f...

journal_title：Infection and drug resistance

authors： Guo W,Gao B,Li L,Gai W,Yang J,Zhang Y,Wang L

更新日期：2019-08-08 00:00:00

abstract：Objective:Candida albicans is a yeast with multiple genotypes. It's a commensal fungus colonizing various sites. However, when the host's immune system weakens, it becomes pathogenic and is responsible for various lesions. In Burkina Faso, antifungal drugs are frequently used, particularly fluconazole, the most used sy...

journal_title：Infection and drug resistance

authors： Sawadogo PM,Zida A,Soulama I,Sermé SS,Guiguemdé KT,Junior R,Sangaré I,Bamba S,Ouédraogo-Traoré R,Guiguemdé TR

更新日期：2019-12-16 00:00:00

abstract：:Ceftaroline is an advanced-generation cephalosporin antibiotic recently approved by the US Food and Drug Administration for the treatment of complicated skin and skin-structure infections (cSSSIs). This intravenous broad-spectrum antibiotic exerts potent bactericidal activity by inhibiting bacterial cell wall synthesi...

journal_title：Infection and drug resistance

authors： Hernandez PO,Lema S,Tyring SK,Mendoza N

更新日期：2012-01-01 00:00:00

abstract：Objective:The aim of this study was to investigate the in vitro antimicrobial susceptibilities of clinically important Gram-negative bacteria from seven intensive care units in Taiwan in 2016. Materials and methods:In total, 300 non-duplicate isolates of Escherichia coli (n=100), Klebsiella pneumoniae (n=100), and Pse...

journal_title：Infection and drug resistance

authors： Liao CH,Lee NY,Tang HJ,Lee SS,Lin CF,Lu PL,Wu JJ,Ko WC,Lee WS,Hsueh PR

更新日期：2019-03-04 00:00:00

abstract：Purpose:To characterize the genetic feature of the carbapenems resistant Acinetobacter johnsonii strain Acsw19 isolated from municipal sludge. This strain was found to carry two copies of blaNDM-1,cmlB1-like gene, and blaOXA-211-like gene along with other 8 antimicrobial resistance genes, 3 plasmids, 15 genomic islands...

journal_title：Infection and drug resistance

authors： Tang L,Shen W,Zhang Z,Zhang J,Wang G,Xiang L,She J,Hu X,Zou G,Zhu B,Zhou Y

更新日期：2020-03-23 00:00:00

abstract：Background and purpose:Invasive nontyphoidal salmonellosis, mostly caused by serovars Typhimurium and Enteritidis of Salmonella enterica, has emerged as a major public health problem in sub-Saharan Africa. The aim of this study was the clinical and microbiological characterization of nontyphoidal salmonellosis episodes...

journal_title：Infection and drug resistance

authors： García V,Mandomando I,Ruiz J,Herrera-León S,Alonso PL,Rodicio MR

更新日期：2018-01-31 00:00:00

abstract：Background:Acinetobacter baumannii has emerged as an important pathogen associated with hospital- and community-acquired infections. Community-acquired A. baumannii pneumonia is characterized by a fulminant course and high mortality rates. In this study, we report the identification of a community-acquired carbapenem-r...

journal_title：Infection and drug resistance

authors： Jia H,Sun Q,Ruan Z,Xie X

更新日期：2019-06-06 00:00:00

abstract：Background:China is one of the high-burden countries for multidrug-resistant tuberculosis (MDR-TB), and pyrazinamide is one of the anti-TB drugs used for the shorter MDR-TB treatment regimen. The aim of this study was to determine the correlation between pncA gene mutations and resistance to four first-line anti-TB dru...

journal_title：Infection and drug resistance

authors： Cao Z,Lan Y,Chen L,Xiang M,Peng Z,Zhang J,Zhang H

更新日期：2019-09-30 00:00:00

abstract：Background:Raw meat is one of the commonly consumed traditional diets in Ethiopia. However, unhygienic processing and distribution practices are risky for contamination of meat leading to human infection. This study was conducted to assess the presence of multi-drug resistant E. coli with special emphasis on E. coli O1...

journal_title：Infection and drug resistance

authors： Sebsibe MA,Asfaw ET

更新日期：2020-10-27 00:00:00

abstract：Purpose:This study aims to 1) describe the distribution characteristics of teicoplanin trough concentration (Cmin) and explore the related influencing factors and 2) evaluate the nephrotoxicity of teicoplanin in children. Patients and Methods:A cohort of children who were treated with teicoplanin intravenously were in...

journal_title：Infection and drug resistance

authors： Sun D,Zhang T,Mi J,Dong Y,Liu Y,Zhang Y,Zhang D,Wang T,Cheng H,Dong Y

更新日期：2020-11-12 00:00:00

abstract：Introduction:Management of ventilator-associated pneumonia (VAP), the most common infection in patients on mechanical ventilation, should be tailored to local microbiological data. The aim of this study was to determine susceptibility patterns of organisms causing VAP to develop a treatment algorithm based on these fin...

journal_title：Infection and drug resistance

authors： Awad LS,Abdallah DI,Mugharbil AM,Jisr TH,Droubi NS,El-Rajab NA,Moghnieh RA

更新日期：2017-12-22 00:00:00

abstract：:The increase in hospitalization due to acute bacterial skin and skin structure infections (ABSSSI) caused by resistant pathogens supports the need for new treatment options. Antimicrobial options for ABSSSI that provide broad-spectrum coverage, including gram-negative pathogens and multidrug-resistant gram-positive ba...

journal_title：Infection and drug resistance

authors： Righi E,Carnelutti A,Vena A,Bassetti M

更新日期：2018-04-04 00:00:00

abstract：Purpose:With the recommendation of World Health Organization (WHO) and as per the Ethiopian National Implementation Guideline, GeneXpert is used for rapid diagnosis of rifampicin (RIF)-resistant multidrug-resistant tuberculosis (MDR-TB) from the suspected TB patients; however, there were limited findings in Ethiopia pa...

journal_title：Infection and drug resistance

authors： Zewdie O,Dabsu R,Kifle E,Befikadu D

更新日期：2020-10-20 00:00:00

abstract：:[This corrects the article DOI: 10.2147/IDR.S258379.]. ...

journal_title：Infection and drug resistance

authors：

更新日期：2020-09-04 00:00:00

abstract：Background:Bloodstream infection (BSI) caused by carbapenem-resistant Enterobacteriaceae are potentially life-threatening related to poorer outcomes. Colistin is considered one of the last-resort treatments against human infections caused by multidrug-resistant (MDR) Gram-negative bacteria. Therefore, emergence of stra...

journal_title：Infection and drug resistance

authors： Lin M,Yang Y,Yang Y,Chen G,He R,Wu Y,Zhong LL,El-Sayed Ahmed MAE,Feng S,Shen C,Wen X,Huang J,Li H,Zheng X,Tian GB

更新日期：2020-05-12 00:00:00

abstract：Objective:An ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method for the determination of selinexor was established to investigate the effects of isavuconazole, itraconazole and fluconazole on the pharmacokinetics of selinexor in rats, respectively. Methods:Twenty-four healthy male rat...

journal_title：Infection and drug resistance

authors： Li SL,Zhang Y,Cheng QS,Xin JZ,Dong ZQ,Qiu XJ

更新日期：2020-09-14 00:00:00

abstract：BACKGROUND:Candida spp. are a frequent cause of nosocomial bloodstream infections worldwide. OBJECTIVE:To evaluate the use patterns and outcomes associated with intravenous (IV) fluconazole therapy in intensive care units in Spain and Germany. PATIENTS AND METHODS:The research reported here was a prospective multicen...

journal_title：Infection and drug resistance

authors： Wissing H,Ballus J,Bingold TM,Nocea G,Krobot KJ,Kaskel P,Kumar RN,Mavros P

更新日期：2013-01-01 00:00:00

abstract：Background:In Saudi Arabia, cross-border transmission of multidrug-resistant (MDR) Mycobacterium tuberculosis complex (MTBC) strains might be particularly fostered by high immigration rates. Herein, we aimed to elucidate the transmission dynamics of MDR-MTBC strains and reveal a detailed prediction of all resistance-co...

journal_title：Infection and drug resistance

authors： Al-Ghafli H,Kohl TA,Merker M,Varghese B,Halees A,Niemann S,Al-Hajoj S

更新日期：2018-11-12 00:00:00