PAU-1, a Novel Plasmid-Encoded Ambler Class A β-Lactamase Identified in a Clinical Pseudomonas aeruginosa Isolate.

abstract：:While MIC distributions and percent susceptibility for cefepime and ceftazidime are generally similar among Pseudomonas aeruginosa, we noted an increasing discordance in susceptibility favoring ceftazidime at our hospital. Quantitative reverse transcriptase-polymerase chain reaction was utilized to explore overexpress...

journal_title：Infection and drug resistance

authors： Laohavaleeson S,Lolans K,Quinn JP,Kuti JL,Nicolau DP

更新日期：2008-01-01 00:00:00

abstract：:Mycoplasma genitalium is one of the important causes of non-gonococcal urethritis. Rising incidence and emerging antimicrobial resistance are a major concern these days. The poor clinical outcomes with doxycycline therapy led to the use of azithromycin as the primary drug of choice. Single-dose azithromycin regimen ov...

journal_title：Infection and drug resistance

authors： Sethi S,Zaman K,Jain N

更新日期：2017-09-01 00:00:00

abstract：Background:Hepatitis E virus (HEV) is an emerging infectious agent that causes acute hepatitis in developing and developed countries. Diagnosis of HEV infection has not been routinely done in Egyptian hospitals, and clinicians do not prescribe ribavirin (RBV) for acute hepatitis cases of unknown etiology (AHUE). We aim...

journal_title：Infection and drug resistance

authors： Sayed IM,El-Mokhtar MA,Mahmoud MAR,Elkhawaga AA,Gaber S,Seddek NH,Abdel-Wahid L,Ashmawy AM,Alkareemy EAR

更新日期：2021-01-12 00:00:00

abstract：Background:Gram-negative bacteria bloodstream infection (GNB-BSI) results in considerable mortality and hospitality costs in cirrhotic patients. β-lactam/β-lactamase inhibitor combinations (BLBLIs) and carbapenems (CARs) are widely recommended for treating GNB-BSI in cirrhotic patients, while the efficacy and cost-effe...

journal_title：Infection and drug resistance

authors： Dong Y,Li Y,Zhang Y,Sun D,Du Q,Zhang T,Teng M,Han R,Wang Y,Zhu L,Lei J,Dong Y,Wang T

更新日期：2020-05-07 00:00:00

abstract：:The mortality rate for candidemia is approximately 30%-60%. However, prognostic factors in patients with candidemia have not yet been elucidated in detail. The aim of the present study was to analyze prognostic factors for candidemia using the mortality rate and Candida isolates of patients with candidemia. Seventy-fi...

journal_title：Infection and drug resistance

authors： Hirano R,Sakamoto Y,Kudo K,Ohnishi M

更新日期：2015-07-08 00:00:00

abstract：Purpose:To investigate the occurrence and genetic characteristics of the blaIMP-26-positive plasmid from a multidrug-resistant clinical isolate, Enterobacter hormaechei L51. Methods:Species identification was determined by MALDI-TOF MS and Sanger sequencing. Antimicrobial susceptibility testing was performed by the ag...

journal_title：Infection and drug resistance

authors： Gou JJ,Liu N,Guo LH,Xu H,Lv T,Yu X,Chen YB,Guo XB,Rao YT,Zheng BW

更新日期：2020-02-20 00:00:00

abstract：OBJECTIVES:Moxifloxacin (MXF) has been advocated for the treatment of extensively drug-resistant (XDR) tuberculosis despite resistance to older-generation fluoroquinolones. We investigated the relationship between the minimum inhibitory concentration (MIC) of MXF and mutations in the gyrA and gyrB genes in Mycobacteriu...

journal_title：Infection and drug resistance

authors： Dookie N,Sturm AW,Moodley P

更新日期：2014-08-19 00:00:00

abstract：Background:The incidence of human papilloma virus (HPV) infections in conservative populations is increasing, yet vaccination is not routinely recommended by primary health care (PHC) physicians. The aim of this study is to evaluate PHC physicians' awareness of HPV infections and vaccination in Saudi Arabia. Materials...

journal_title：Infection and drug resistance

authors： Almughais ES,Alfarhan A,Salam M

更新日期：2018-11-15 00:00:00

abstract：Purpose:This study aims to 1) describe the distribution characteristics of teicoplanin trough concentration (Cmin) and explore the related influencing factors and 2) evaluate the nephrotoxicity of teicoplanin in children. Patients and Methods:A cohort of children who were treated with teicoplanin intravenously were in...

journal_title：Infection and drug resistance

authors： Sun D,Zhang T,Mi J,Dong Y,Liu Y,Zhang Y,Zhang D,Wang T,Cheng H,Dong Y

更新日期：2020-11-12 00:00:00

abstract：Purpose:Plasmids of the incompatibility group X type 3 (IncX3) were described carrying various carbapenemase genes in carbapenemase-producing Enterobacteriaceae (CPE) worldwide and in the United Arab Emirates (UAE), as well. To understand the driving force behind the emergence of such plasmids in the UAE, the relations...

journal_title：Infection and drug resistance

authors： Mouftah SF,Pál T,Darwish D,Ghazawi A,Villa L,Carattoli A,Sonnevend Á

更新日期：2019-06-21 00:00:00

abstract：INTRODUCTION:The characteristics and antimicrobial resistance profiles of Staphylococcus aureus differs according to geographical regions and in relation to antibiotic usage. The aim of this study was to determine the biochemical characteristics of the prevalent S. aureus from Ekiti State, Nigeria, and to evaluate thre...

journal_title：Infection and drug resistance

authors： Olowe OA,Kukoyi OO,Taiwo SS,Ojurongbe O,Opaleye OO,Bolaji OS,Adegoke AA,Makanjuola OB,Ogbolu DO,Alli OT

更新日期：2013-08-20 00:00:00

abstract：Background:Heteroresistance is a phenomenon that occurs in all bacteria and can cause treatment failure. Yet, the exact mechanisms responsible for heteroresistance still remain unknown. The following study investigated the mechanisms of imipenem-heteroresistance and -resistance in Pseudomonas aeruginosa clinical isolat...

journal_title：Infection and drug resistance

authors： Xu Y,Zheng X,Zeng W,Chen T,Liao W,Qian J,Lin J,Zhou C,Tian X,Cao J,Zhou T

更新日期：2020-05-14 00:00:00

abstract：:A systematic review was conducted to determine the distribution and prevalence of antibiotic-resistant bacteria (ARB), antimicrobial-resistant genes (ARGs), and antimicrobial-resistant gene determinants (ARGDs) in clinical, environmental, and farm settings and to identify key knowledge gaps in a bid to contain their s...

journal_title：Infection and drug resistance

authors： Ekwanzala MD,Dewar JB,Kamika I,Momba MNB

更新日期：2018-10-17 00:00:00

abstract：Purpose:Antifungal resistance and virulence properties of Candida albicans (C. albicans) are growing health problems worldwide. The present study aims to investigate the effect of Zinc Oxide (ZnO) nanoparticles and Nystatin on SAP1-3 genes expression in C. albicans isolates of females with Vulvovaginal Candidiasis (VVC...

journal_title：Infection and drug resistance

authors： Hosseini SS,Joshaghani H,Shokohi T,Ahmadi A,Mehrbakhsh Z

更新日期：2020-02-13 00:00:00

abstract：Background:China is one of the high-burden countries for multidrug-resistant tuberculosis (MDR-TB), and pyrazinamide is one of the anti-TB drugs used for the shorter MDR-TB treatment regimen. The aim of this study was to determine the correlation between pncA gene mutations and resistance to four first-line anti-TB dru...

journal_title：Infection and drug resistance

authors： Cao Z,Lan Y,Chen L,Xiang M,Peng Z,Zhang J,Zhang H

更新日期：2019-09-30 00:00:00

abstract：Background:China is facing a great challenge of pulmonary nontuberculous mycobacteria (NTM) infections. This primary objective of this study was to assess the prevalence of NTM isolates among patients with presumptive TB in Fujian. Methods:The mycobacterial isolates were collected from the tuberculosis survey from Fuj...

journal_title：Infection and drug resistance

authors： Lin S,Wei S,Zhao Y,Lin J,Pang Y

更新日期：2019-11-12 00:00:00

abstract：Introduction:Candida species, one among the opportunistic fungi, has become a common pathogen causing vaginal thrush and nosocomial bloodstream infections (BSIs). This study aims to evaluate the prevalence and antifungal susceptibility of various Candida species and slime production by Candida species in BSIs and vulvo...

journal_title：Infection and drug resistance

authors： Tulasidas S,Rao P,Bhat S,Manipura R

更新日期：2018-11-23 00:00:00

abstract：:Enterococci have been implicated as an emerging important cause of several diseases and multiple antibiotic resistance. However, there is little information about the prevalence of pathogenic and/or antibiotic-resistant Enterococcus faecalis in ready-to-eat foods in Nigeria. Here we report the pathogenic potential of ...

journal_title：Infection and drug resistance

authors： Olawale AK,David OM,Oluyege AO,Osuntoyinbo RT,Laleye SA,Famurewa O

更新日期：2015-06-26 00:00:00

abstract：Purpose:The problem of carbapenem-resistant Pseudomonas aeruginosa in health-care settings is growing worse. This study was conducted to investigate the rate of carbapenemase genes, antibiotic resistance, and virulence factors in carbapenem-resistant P. aeruginosa associated with hospital-acquired infections. Patients...

journal_title：Infection and drug resistance

authors： El-Mahdy R,El-Kannishy G

更新日期：2019-11-07 00:00:00

abstract：:One of the main fundamental mechanisms of antibiotic resistance in Gram-negative bacteria comprises an effective change in the membrane permeability to antibiotics. The Gram-negative bacterial complex cell envelope comprises an outer membrane that delimits the periplasm from the exterior environment. The outer membran...

journal_title：Infection and drug resistance

authors： Ghai I,Ghai S

更新日期：2017-08-30 00:00:00

abstract：:Echinocandin antifungal agents have become the first-line therapy for invasive candidiasis (IC) in many countries. Despite their increasing use, resistance to this class of drug is, overall, still uncommon. Here, we report two patients from the People's Republic of China with IC, one with infection caused by pan-echin...

journal_title：Infection and drug resistance

authors： Xiao M,Fan X,Hou X,Chen SC,Wang H,Kong F,Sun ZY,Chu YZ,Xu YC

更新日期：2018-01-23 00:00:00

abstract：:While methicillin-resistant Staphylococcus aureus (MRSA) bacteremia has poor outcomes, we describe our experience with Ceftobiprole mainly as a combination therapy for the treatment of MRSA bacteremia. All the cases of MRSA bacteremia in our center at the King Abdulaziz Medical City (KAMC), Riyadh, that had undergone ...

journal_title：Infection and drug resistance

authors： Mahmoud E,Al Mansour S,Bosaeed M,Alharbi A,Alsaedy A,Aljohani S,Alalwan B,Alothman A

更新日期：2020-08-03 00:00:00

abstract：:Background: There have been no reports in Bulgaria about quinolone resistance determinants among Enterobacter spp. Aims: To investigate plasmid and chromosomal quinolone resistance rates among 175 third-generation cephalosporin resistant Enterobacter spp. isolates (167 Enterobacter cloacae complex and eight Enterobact...

journal_title：Infection and drug resistance

authors： Markovska R,Stoeva T,Dimitrova D,Boyanova L,Stankova P,Mihova K,Mitov I

更新日期：2019-05-28 00:00:00

abstract：Background:Recurrent tuberculosis (TB) following TB treatment completion in HIV-infected individuals remains a major public health burden. We assessed the role of various risk factors in mediating the development of recurrent TB and subsequent resistance to antiretroviral therapy and anti-TB drugs. Patients and method...

journal_title：Infection and drug resistance

authors： Naidoo K,Dookie N,Naidoo K,Yende-Zuma N,Chimukangara B,Bhushan A,Govender D,Gengiah S,Padayatchi N

更新日期：2018-09-05 00:00:00

abstract：Introduction:Helicobacter pylori was discovered first in the stomachs of patients with gastritis and ulcers by Marshall and Warren in 1982. This discovery majorly affected many research areas of gastroenterology. Since then, the main aim has been to eradicate this microaerophilic bacterium from the stomachs of infected...

journal_title：Infection and drug resistance

authors： Khani S,Talebi Bezmin Abadi A,Mohabati Mobarez A

更新日期：2019-11-01 00:00:00

abstract：Purpose:The activity of the cationic antimicrobial peptide WLBU2 was evaluated against planktonic cells and biofilms of multi-drug resistant (MDR) Acinetobacter baumannii and Klebsiella pneumoniae, alone and in combination with classical antimicrobial agents. Methods:Control American Type Culture Collection (ATCC) str...

journal_title：Infection and drug resistance

authors： Swedan S,Shubair Z,Almaaytah A

更新日期：2019-07-09 00:00:00

abstract：Purpose:Respiratory viruses are important etiologies of community-acquired pneumonia (CAP). However, the impact of different RVs on the outcomes of CAP is not well elucidated. This study aims to compare the clinical features and severity of influenza (Flu-p) and non-influenza respiratory viruses-related pneumonia (NIRV...

journal_title：Infection and drug resistance

authors： Chen L,Han XD,Li YL,Zhang CX,Xing XQ

更新日期：2020-10-08 00:00:00

abstract：:Rilpivirine is associated with a good efficacy and safety profile. However, data from real-life settings are scarce. Methods:We investigated the durability, safety and efficacy of Rilpivirine-based antiretroviral therapy in a prospective, observational, multicenter study. Results:We enrolled 499 HIV-infected patient...

journal_title：Infection and drug resistance

authors： Bagella P,De Socio GV,Ricci E,Menzaghi B,Martinelli C,Squillace N,Maggi P,Orofino G,Calza L,Carenzi L,Celesia BM,Penco G,Di Biagio A,Valsecchi L,Vichi F,Colombo V,Parruti G,Dentone C,Falasca K,Bonfanti P,Madeddu G

更新日期：2018-04-26 00:00:00

abstract：Background:Acinetobacter baumannii has emerged as an important pathogen associated with hospital- and community-acquired infections. Community-acquired A. baumannii pneumonia is characterized by a fulminant course and high mortality rates. In this study, we report the identification of a community-acquired carbapenem-r...

journal_title：Infection and drug resistance

authors： Jia H,Sun Q,Ruan Z,Xie X

更新日期：2019-06-06 00:00:00

abstract：Purpose:The flavohemoprotein (gFlHb) in Giardia plays an important role in managing nitrosative and oxidative stress, and potentially also in virulence and nitroimidazole drug tolerance. The aim of this study was to analyze the genetic diversity of gFlHb in Giardia assemblages A and B clinical isolates. Methods:gFlHb ...

journal_title：Infection and drug resistance

authors： Saghaug CS,Klotz C,Kallio JP,Aebischer T,Langeland N,Hanevik K

更新日期：2020-12-18 00:00:00