Expression of the MexXY-OprM efflux system in Pseudomonas aeruginosa with discordant cefepime/ceftazidime susceptibility profiles.

abstract：Purpose:Respiratory viruses are important etiologies of community-acquired pneumonia (CAP). However, the impact of different RVs on the outcomes of CAP is not well elucidated. This study aims to compare the clinical features and severity of influenza (Flu-p) and non-influenza respiratory viruses-related pneumonia (NIRV...

journal_title：Infection and drug resistance

authors： Chen L,Han XD,Li YL,Zhang CX,Xing XQ

更新日期：2020-10-08 00:00:00

abstract：Purpose:The aim was to examine the clinical characteristics and risk factors for bloodstream infection (BSI) due to carbapenem-resistant Klebsiella pneumoniae (CRKP) in patients with hematologic malignancies. Materials and Methods:A single-centre, retrospective case-control study representing 734 patients with hematol...

journal_title：Infection and drug resistance

authors： Zhang P,Wang J,Hu H,Zhang S,Wei J,Yang Q,Qu T

更新日期：2020-09-22 00:00:00

abstract：Introduction:Escherichia (E.) coli can cause intestinal and extra-intestinal infections which ranged from mild to life-threatening infections. The severity of infection is a product of many factors including virulence properties and antimicrobial resistance. Objectives:To determine the antibiotic resistance pattern, t...

journal_title：Infection and drug resistance

authors： Abd El-Baky RM,Ibrahim RA,Mohamed DS,Ahmed EF,Hashem ZS

更新日期：2020-04-28 00:00:00

abstract：Introduction:To achieve target concentrations, the application of higher-than-standard doses of amikacin is proposed for the treatment of sepsis due to an increase in volume of distribution and clearance, but little data are available on aminoglycoside administration in critically ill elderly patients. Patients and me...

journal_title：Infection and drug resistance

authors： Sadeghi K,Hamishehkar H,Najmeddin F,Ahmadi A,Hazrati E,Honarmand H,Mojtahedzadeh M

更新日期：2018-02-13 00:00:00

abstract：Background:Broad-scale evidence has shown the significant association between ambient air pollutants and the development of tuberculosis (TB). However, the impact of air quality on the risk of TB in Taiwan is still poorly understood. Objective:To develop a probabilistic integrated population-level risk assessment appr...

journal_title：Infection and drug resistance

authors： Lin YJ,Lin HC,Yang YF,Chen CY,Ling MP,Chen SC,Chen WY,You SH,Lu TH,Liao CM

更新日期：2019-12-06 00:00:00

abstract：Background and purpose:Invasive nontyphoidal salmonellosis, mostly caused by serovars Typhimurium and Enteritidis of Salmonella enterica, has emerged as a major public health problem in sub-Saharan Africa. The aim of this study was the clinical and microbiological characterization of nontyphoidal salmonellosis episodes...

journal_title：Infection and drug resistance

authors： García V,Mandomando I,Ruiz J,Herrera-León S,Alonso PL,Rodicio MR

更新日期：2018-01-31 00:00:00

abstract：Purpose:Plasmids of the incompatibility group X type 3 (IncX3) were described carrying various carbapenemase genes in carbapenemase-producing Enterobacteriaceae (CPE) worldwide and in the United Arab Emirates (UAE), as well. To understand the driving force behind the emergence of such plasmids in the UAE, the relations...

journal_title：Infection and drug resistance

authors： Mouftah SF,Pál T,Darwish D,Ghazawi A,Villa L,Carattoli A,Sonnevend Á

更新日期：2019-06-21 00:00:00

abstract：Purpose:To develop a rapid EDTA-modified carbapenem inactivation method (reCIM) combined with modified rapid carbapenem inactivation method (mrCIM) to detect carbapenemase and distinguish metallo-β-lactamases from carbapenemases in Enterobacteriaceae in 4 hrs. Materials and Methods:The sensitivities and specificities ...

journal_title：Infection and drug resistance

authors： Wei Q,Sun J,Wang Z,Yan L,Zhang C,Xu X

更新日期：2020-06-23 00:00:00

abstract：Objective:Evaluate host and pathogen factors associated with mortality in those with hospital acquired infections (HAI) in a tertiary intensive care unit in Brazil. Methods:Observational and analytical cohort single center study in a general intensive care unit (ICU) in Northeastern Brazil between January 2016 and Aug...

journal_title：Infection and drug resistance

authors： Otero ML,Menezes RC,Ferreira IBB,Issa FL,Agareno G,Carmo TA,Arriaga MB,Fukutani KF,Pamplona Neto L,Agareno S,Filgueiras Filho NM,Akrami KM,Andrade BB

更新日期：2020-08-12 00:00:00

abstract：Background:Due to increasing colistin usage, the dissemination of the colistin-resistant gene mcr-1 has been increasingly investigated. The aim of this study was to determine whether a traveler on a short-term international trip to a developing country could bring mcr-1 back to their home country. Materials and method...

journal_title：Infection and drug resistance

authors： Nakayama T,Kumeda Y,Kawahara R,Yamaguchi T,Yamamoto Y

更新日期：2018-03-12 00:00:00

abstract：:Rilpivirine is associated with a good efficacy and safety profile. However, data from real-life settings are scarce. Methods:We investigated the durability, safety and efficacy of Rilpivirine-based antiretroviral therapy in a prospective, observational, multicenter study. Results:We enrolled 499 HIV-infected patient...

journal_title：Infection and drug resistance

authors： Bagella P,De Socio GV,Ricci E,Menzaghi B,Martinelli C,Squillace N,Maggi P,Orofino G,Calza L,Carenzi L,Celesia BM,Penco G,Di Biagio A,Valsecchi L,Vichi F,Colombo V,Parruti G,Dentone C,Falasca K,Bonfanti P,Madeddu G

更新日期：2018-04-26 00:00:00

abstract：Background:Leishmaniasis is an infectious disease common in tropical and subtropical regions caused by the genus Leishmania, which is transmitted by the bite of female sandflies. In this study, we evaluate the anti-leishmanial effect of recombinant Clostridium α-toxin protein alone and the combination with glucantime t...

journal_title：Infection and drug resistance

authors： Namdar F,Khanahmad H,Ghayour Z,Mirzaei F,Namdar A,Aghaei M,Izadi S,Khamesipour F,Hejazi SH

更新日期：2020-07-15 00:00:00

abstract：Purpose:The problem of carbapenem-resistant Pseudomonas aeruginosa in health-care settings is growing worse. This study was conducted to investigate the rate of carbapenemase genes, antibiotic resistance, and virulence factors in carbapenem-resistant P. aeruginosa associated with hospital-acquired infections. Patients...

journal_title：Infection and drug resistance

authors： El-Mahdy R,El-Kannishy G

更新日期：2019-11-07 00:00:00

abstract：Background:Gram-negative bacteria bloodstream infection (GNB-BSI) results in considerable mortality and hospitality costs in cirrhotic patients. β-lactam/β-lactamase inhibitor combinations (BLBLIs) and carbapenems (CARs) are widely recommended for treating GNB-BSI in cirrhotic patients, while the efficacy and cost-effe...

journal_title：Infection and drug resistance

authors： Dong Y,Li Y,Zhang Y,Sun D,Du Q,Zhang T,Teng M,Han R,Wang Y,Zhu L,Lei J,Dong Y,Wang T

更新日期：2020-05-07 00:00:00

abstract：:Primary infection with human herpesvirus-6 (HHV-6) commonly occurs at an early age in children, most often at 3 years of age, and is associated with childhood diseases, such as exanthema subitum, hepatitis, febrile convulsions, or encephalitis. However, the virus occasionally reactivates from its latent state in immun...

journal_title：Infection and drug resistance

authors： Kuwahara-Ota S,Chinen Y,Mizuno Y,Takimoto-Shimomura T,Matsumura-Kimoto Y,Tanba K,Tsukamoto T,Mizutani S,Shimura Y,Kobayashi T,Horiike S,Kuroda J

更新日期：2018-05-14 00:00:00

abstract：Purpose:The purpose of this study was to identify the common clinical presentations and the evidence on the presence of ageusia and anosmia as an emerging coronavirus disease 2019 (COVID-19) symptom to better inform in both COVID-19 patients and clinicians. Patients and Methods:As part of a double-institutional collab...

journal_title：Infection and drug resistance

authors： Farah Yusuf Mohamud M,Garad Mohamed Y,Mohamed Ali A,Ali Adam B

更新日期：2020-07-29 00:00:00

abstract：Background:COVID-19 caused by SARS-CoV-2 virus emerged as an unprecedented challenge to discover effective drugs for its prevention and cure. Hyperinflammation-induced lung damage is one of the poor prognostic indicators causing a higher rate of morbidity and mortality of COVID-19 patients. Favipiravir, an antiviral dr...

journal_title：Infection and drug resistance

authors： Kaur RJ,Charan J,Dutta S,Sharma P,Bhardwaj P,Sharma P,Lugova H,Krishnapillai A,Islam S,Haque M,Misra S

更新日期：2020-12-14 00:00:00

abstract：:We present here the first report of an OXA-181-producing Klebsiella pneumoniae isolated from the fecal specimen of a patient in China. The OXA-181-encoding gene blaOXA-181 was located on a 51 kb IncX3-type plasmid. Conjugation assay and whole-genome sequencing analysis revealed that this transferrable plasmid in the K...

journal_title：Infection and drug resistance

authors： Liu C,Fang Y,Zeng Y,Lu J,Sun Q,Zhou H,Shen Z,Chen G

更新日期：2020-04-06 00:00:00

abstract：:The mortality rate for candidemia is approximately 30%-60%. However, prognostic factors in patients with candidemia have not yet been elucidated in detail. The aim of the present study was to analyze prognostic factors for candidemia using the mortality rate and Candida isolates of patients with candidemia. Seventy-fi...

journal_title：Infection and drug resistance

authors： Hirano R,Sakamoto Y,Kudo K,Ohnishi M

更新日期：2015-07-08 00:00:00

abstract：Objective:In the present study, we aimed to describe the clinical features, diagnosis, treatment, and prognosis of spinal epidural abscess (SEA). Methods:The complete clinical data of 11 SEA patients who were treated in our hospital system from January 2015 to June 2018 were retrospectively analyzed. Moreover, the cli...

journal_title：Infection and drug resistance

authors： Dai G,Li S,Yin C,Sun Y,Xu D,Wang Z,Luan L,Hou J,Wang T

更新日期：2020-09-29 00:00:00

abstract：Background:In Saudi Arabia, cross-border transmission of multidrug-resistant (MDR) Mycobacterium tuberculosis complex (MTBC) strains might be particularly fostered by high immigration rates. Herein, we aimed to elucidate the transmission dynamics of MDR-MTBC strains and reveal a detailed prediction of all resistance-co...

journal_title：Infection and drug resistance

authors： Al-Ghafli H,Kohl TA,Merker M,Varghese B,Halees A,Niemann S,Al-Hajoj S

更新日期：2018-11-12 00:00:00

abstract：Background:Acinetobacter baumannii has emerged as an important pathogen associated with hospital- and community-acquired infections. Community-acquired A. baumannii pneumonia is characterized by a fulminant course and high mortality rates. In this study, we report the identification of a community-acquired carbapenem-r...

journal_title：Infection and drug resistance

authors： Jia H,Sun Q,Ruan Z,Xie X

更新日期：2019-06-06 00:00:00

abstract：:The rapid detection of carbapenemase allows implementation of infection control measures and adaptation of antibiotic therapy. We evaluated the performances of the Xpert Carba-R V2® assay for the direct detection and identification of carbapenemase on positive blood cultures. We focused our evaluation on its detection...

journal_title：Infection and drug resistance

authors： Cointe A,Walewski V,Hobson CA,Doit C,Bidet P,Dortet L,Bonacorsi S,Birgy A

更新日期：2019-10-23 00:00:00

abstract：:Despite intensive efforts to eradicate the disease, tuberculosis continues to be a major threat to Indian society, with an estimated prevalence of 3.45 million cases in 2006. Emergence of multidrug-resistant tuberculosis has complicated eradication attempts in recent years. Incomplete and/inadequate treatment are the ...

journal_title：Infection and drug resistance

authors： Yashodhara BM,Huat CB,Naik LN,Umakanth S,Hande M,Pappachan JM

更新日期：2010-01-01 00:00:00

abstract：Background:Flomoxef is potentially effective against β-lactamase-producing Enterobacteriaceae because limited clinical data demonstrate its effectiveness against Enterobacteriaceae bloodstream infections (BSIs) based on its minimum inhibitory concentrations (MICs). This study was conducted to determine the optimal brea...

journal_title：Infection and drug resistance

authors： Lee CH,Chen IL,Li CC,Chien CC

更新日期：2018-11-27 00:00:00

abstract：Purpose:To characterize the genetic feature of the carbapenems resistant Acinetobacter johnsonii strain Acsw19 isolated from municipal sludge. This strain was found to carry two copies of blaNDM-1,cmlB1-like gene, and blaOXA-211-like gene along with other 8 antimicrobial resistance genes, 3 plasmids, 15 genomic islands...

journal_title：Infection and drug resistance

authors： Tang L,Shen W,Zhang Z,Zhang J,Wang G,Xiang L,She J,Hu X,Zou G,Zhu B,Zhou Y

更新日期：2020-03-23 00:00:00

abstract：:Streptococcus pneumonia is a rare cause of pyogenic sacroiliitis and osteomyelitis. A case of pneumococcal sacroiliitis and osteomyelitis is reported herein. The patient was a previously healthy 54-year-old man with a 3-day history of fever and a 3-week history of increasing right-side thigh pain. Computed tomography ...

journal_title：Infection and drug resistance

authors： Hadano Y,Chang B

更新日期：2018-08-03 00:00:00

abstract：Objective:To genetically characterize clusters of virulence factors (VFs) among extended spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae and assess whether these clusters are associated with genetic determinants or clinical outcomes. Methods:One hundred forty-eight E. coli and 82 K. pn...

journal_title：Infection and drug resistance

authors： Surgers L,Boersma P,Girard PM,Homor A,Geneste D,Arlet G,Decré D,Boyd A

更新日期：2018-12-31 00:00:00

abstract：Purpose:Pseudomonas aeruginosa is associated with pulmonary function decline and high disease severity in non-cystic fibrosis (CF) bronchiectasis. The prevalence of nontuberculous mycobacteria (NTM) in non-CF bronchiectasis patients has increased recently. This study investigated the impact of NTM with or without P. ae...

journal_title：Infection and drug resistance

authors： Hsieh MH,Lin CY,Wang CY,Fang YF,Lo YL,Lin SM,Lin HC

更新日期：2018-08-10 00:00:00

abstract：BACKGROUND:Candida spp. are a frequent cause of nosocomial bloodstream infections worldwide. OBJECTIVE:To evaluate the use patterns and outcomes associated with intravenous (IV) fluconazole therapy in intensive care units in Spain and Germany. PATIENTS AND METHODS:The research reported here was a prospective multicen...

journal_title：Infection and drug resistance

authors： Wissing H,Ballus J,Bingold TM,Nocea G,Krobot KJ,Kaskel P,Kumar RN,Mavros P

更新日期：2013-01-01 00:00:00