Evaluation of Modified Rapid Carbapenem Inactivation Method (mrCIM) Combined with Rapid EDTA-Modified Carbapenem Inactivation Method (reCIM) to Detect Carbapenemase and Distinguish Metallo-Carbapenemase in Enterobacteriaceae Within Four Hours.

abstract：BACKGROUND:Outpatient parenteral antimicrobial therapy (OPAT) is the administration of intravenous antimicrobial therapy to patients in an outpatient setting. It may be used for patients who have infections that require parenteral treatment but who are otherwise stable enough to not require admission as inpatients. OB...

journal_title：Infection and drug resistance

authors： Al Alawi S,Abdulkarim S,Elhennawy H,Al-Mansoor A,Al Ansari A

更新日期：2015-08-07 00:00:00

abstract：:Raoultella ornithinolytica is an encapsulated Gram-negative, oxidase-negative, catalase-positive, aerobic, non-motile rod that belongs to the Enterobacteriaceae family. This bacterium was initially classified in the genus Klebsiella as Klebsiella ornithinolytica, until the creation of the genus Raoultella in 2001. R. ...

journal_title：Infection and drug resistance

authors： Hajjar R,Ambaraghassi G,Sebajang H,Schwenter F,Su SH

更新日期：2020-04-15 00:00:00

abstract：Introduction:Candida species, one among the opportunistic fungi, has become a common pathogen causing vaginal thrush and nosocomial bloodstream infections (BSIs). This study aims to evaluate the prevalence and antifungal susceptibility of various Candida species and slime production by Candida species in BSIs and vulvo...

journal_title：Infection and drug resistance

authors： Tulasidas S,Rao P,Bhat S,Manipura R

更新日期：2018-11-23 00:00:00

abstract：Background:Hepatitis E virus (HEV) is an emerging infectious agent that causes acute hepatitis in developing and developed countries. Diagnosis of HEV infection has not been routinely done in Egyptian hospitals, and clinicians do not prescribe ribavirin (RBV) for acute hepatitis cases of unknown etiology (AHUE). We aim...

journal_title：Infection and drug resistance

authors： Sayed IM,El-Mokhtar MA,Mahmoud MAR,Elkhawaga AA,Gaber S,Seddek NH,Abdel-Wahid L,Ashmawy AM,Alkareemy EAR

更新日期：2021-01-12 00:00:00

abstract：Background:Infection prevention and control (IPC) is a globally relevant aspect of all health systems impacting the health and safety of both patients and healthcare workers. However, best practices remain a challenge in healthcare delivery especially in resource limited situations. The primary objective of this study ...

journal_title：Infection and drug resistance

authors： Oppong TB,Amponsem-Boateng C,Kyere EKD,Wang Y,Gheisari Z,Oppong EE,Opolot G,Duan G,Yang H

更新日期：2020-11-24 00:00:00

abstract：Background:Colistin acts as the last line of defense against severe infections caused by carbapenem-resistant Enterobacteriaceae. Infections caused by extensively drug-resistant isolates coproducing MCR and carbapenemases have posed a serious public health concern. Purpose:In this study, we reported the first clinical...

journal_title：Infection and drug resistance

authors： Yuan Y,Li Y,Wang G,Li C,Xiang L,She J,Yang Y,Zhong F,Zhang L

更新日期：2019-09-19 00:00:00

abstract：Purpose:Antifungal resistance and virulence properties of Candida albicans (C. albicans) are growing health problems worldwide. The present study aims to investigate the effect of Zinc Oxide (ZnO) nanoparticles and Nystatin on SAP1-3 genes expression in C. albicans isolates of females with Vulvovaginal Candidiasis (VVC...

journal_title：Infection and drug resistance

authors： Hosseini SS,Joshaghani H,Shokohi T,Ahmadi A,Mehrbakhsh Z

更新日期：2020-02-13 00:00:00

abstract：:Mycoplasma genitalium is one of the important causes of non-gonococcal urethritis. Rising incidence and emerging antimicrobial resistance are a major concern these days. The poor clinical outcomes with doxycycline therapy led to the use of azithromycin as the primary drug of choice. Single-dose azithromycin regimen ov...

journal_title：Infection and drug resistance

authors： Sethi S,Zaman K,Jain N

更新日期：2017-09-01 00:00:00

abstract：:While MIC distributions and percent susceptibility for cefepime and ceftazidime are generally similar among Pseudomonas aeruginosa, we noted an increasing discordance in susceptibility favoring ceftazidime at our hospital. Quantitative reverse transcriptase-polymerase chain reaction was utilized to explore overexpress...

journal_title：Infection and drug resistance

authors： Laohavaleeson S,Lolans K,Quinn JP,Kuti JL,Nicolau DP

更新日期：2008-01-01 00:00:00

abstract：Background:Raw meat is one of the commonly consumed traditional diets in Ethiopia. However, unhygienic processing and distribution practices are risky for contamination of meat leading to human infection. This study was conducted to assess the presence of multi-drug resistant E. coli with special emphasis on E. coli O1...

journal_title：Infection and drug resistance

authors： Sebsibe MA,Asfaw ET

更新日期：2020-10-27 00:00:00

abstract：Background:Pseudomonas aeruginosa is an opportunistic pathogen that causes serious nosocomial infections, especially in immunodeficient patients and cystic fibrosis, cancer, and burned individuals. The biofilm that plays an important role in the virulence of P. aeruginosa is under the regulation of quorum sensing and t...

journal_title：Infection and drug resistance

authors： Sharifian P,Yaslianifard S,Fallah P,Aynesazi S,Bakhtiyari M,Mohammadzadeh M

更新日期：2020-07-21 00:00:00

abstract：:The increase in hospitalization due to acute bacterial skin and skin structure infections (ABSSSI) caused by resistant pathogens supports the need for new treatment options. Antimicrobial options for ABSSSI that provide broad-spectrum coverage, including gram-negative pathogens and multidrug-resistant gram-positive ba...

journal_title：Infection and drug resistance

authors： Righi E,Carnelutti A,Vena A,Bassetti M

更新日期：2018-04-04 00:00:00

abstract：Background:Gram-negative bacteria bloodstream infection (GNB-BSI) results in considerable mortality and hospitality costs in cirrhotic patients. β-lactam/β-lactamase inhibitor combinations (BLBLIs) and carbapenems (CARs) are widely recommended for treating GNB-BSI in cirrhotic patients, while the efficacy and cost-effe...

journal_title：Infection and drug resistance

authors： Dong Y,Li Y,Zhang Y,Sun D,Du Q,Zhang T,Teng M,Han R,Wang Y,Zhu L,Lei J,Dong Y,Wang T

更新日期：2020-05-07 00:00:00

abstract：Purpose:Plasmids of the incompatibility group X type 3 (IncX3) were described carrying various carbapenemase genes in carbapenemase-producing Enterobacteriaceae (CPE) worldwide and in the United Arab Emirates (UAE), as well. To understand the driving force behind the emergence of such plasmids in the UAE, the relations...

journal_title：Infection and drug resistance

authors： Mouftah SF,Pál T,Darwish D,Ghazawi A,Villa L,Carattoli A,Sonnevend Á

更新日期：2019-06-21 00:00:00

abstract：:Lucio's phenomenon (LP) is a special reactional state associated with diffuse multibacillary leprosy; both exhibit a limitative global distribution mainly in Mexico and Central America. We report a case of a 28-year-old female leprosy patient in the People's Republic of China, together with LP and positive anticardiol...

journal_title：Infection and drug resistance

authors： Gao W,Chen Z,Jiang H,Shi Y,Zhang W,Wang H

更新日期：2019-04-02 00:00:00

abstract：OBJECTIVES:Moxifloxacin (MXF) has been advocated for the treatment of extensively drug-resistant (XDR) tuberculosis despite resistance to older-generation fluoroquinolones. We investigated the relationship between the minimum inhibitory concentration (MIC) of MXF and mutations in the gyrA and gyrB genes in Mycobacteriu...

journal_title：Infection and drug resistance

authors： Dookie N,Sturm AW,Moodley P

更新日期：2014-08-19 00:00:00

abstract：Purpose:Pseudomonas aeruginosa possesses a large number of resistance mechanisms to different antimicrobials with carbapenems being the most powerful in treating resistant P. aeruginosa. Hence, it is imperative to explore different mechanisms of carbapenems-resistance in P. aeruginosa to achieve successful treatment th...

journal_title：Infection and drug resistance

authors： Hassuna NA,Darwish MK,Sayed M,Ibrahem RA

更新日期：2020-01-30 00:00:00

abstract：Purpose:Pseudomonas aeruginosa is associated with pulmonary function decline and high disease severity in non-cystic fibrosis (CF) bronchiectasis. The prevalence of nontuberculous mycobacteria (NTM) in non-CF bronchiectasis patients has increased recently. This study investigated the impact of NTM with or without P. ae...

journal_title：Infection and drug resistance

authors： Hsieh MH,Lin CY,Wang CY,Fang YF,Lo YL,Lin SM,Lin HC

更新日期：2018-08-10 00:00:00

abstract：Background:The incidence of human papilloma virus (HPV) infections in conservative populations is increasing, yet vaccination is not routinely recommended by primary health care (PHC) physicians. The aim of this study is to evaluate PHC physicians' awareness of HPV infections and vaccination in Saudi Arabia. Materials...

journal_title：Infection and drug resistance

authors： Almughais ES,Alfarhan A,Salam M

更新日期：2018-11-15 00:00:00

abstract：BACKGROUND:Lyme disease is a tick-borne illness caused by the spirochete Borrelia burgdorferi. Although antibiotic therapy is usually effective early in the disease, relapse may occur when administration of antibiotics is discontinued. Studies have suggested that resistance and recurrence of Lyme disease might be due t...

journal_title：Infection and drug resistance

authors： Sapi E,Kaur N,Anyanwu S,Luecke DF,Datar A,Patel S,Rossi M,Stricker RB

更新日期：2011-01-01 00:00:00

abstract：Background:Due to increasing colistin usage, the dissemination of the colistin-resistant gene mcr-1 has been increasingly investigated. The aim of this study was to determine whether a traveler on a short-term international trip to a developing country could bring mcr-1 back to their home country. Materials and method...

journal_title：Infection and drug resistance

authors： Nakayama T,Kumeda Y,Kawahara R,Yamaguchi T,Yamamoto Y

更新日期：2018-03-12 00:00:00

abstract：Background:Ethiopia is one of the 22 high tuberculosis burden countries. In our country. there are limited published data to show the trend analysis of tuberculosis. Hence, we designed this trend analysis to fill the information gap in our study area. Institutional based retrospective cross-sectional study was employed...

journal_title：Infection and drug resistance

authors： Negash H,Legese H,Adhanom G,Mardu F,Tesfay K,Gebreslasie Gebremeskel S,Berhe B

更新日期：2020-02-24 00:00:00

abstract：:Purpose: The aim of this study was to use a network meta-analysis to evaluate the relative efficacy of various agents at preventing invasive fungal infections (IFIs). In this way, suitable prophylactic regimens may be selected for patients with hematopoietic stem cell transplantation (HSCT). Methods: We conducted a sy...

journal_title：Infection and drug resistance

authors： Su HC,Hua YM,Feng IJ,Wu HC

更新日期：2019-05-15 00:00:00

abstract：Purpose:The aim was to examine the clinical characteristics and risk factors for bloodstream infection (BSI) due to carbapenem-resistant Klebsiella pneumoniae (CRKP) in patients with hematologic malignancies. Materials and Methods:A single-centre, retrospective case-control study representing 734 patients with hematol...

journal_title：Infection and drug resistance

authors： Zhang P,Wang J,Hu H,Zhang S,Wei J,Yang Q,Qu T

更新日期：2020-09-22 00:00:00

abstract：:Background: There have been no reports in Bulgaria about quinolone resistance determinants among Enterobacter spp. Aims: To investigate plasmid and chromosomal quinolone resistance rates among 175 third-generation cephalosporin resistant Enterobacter spp. isolates (167 Enterobacter cloacae complex and eight Enterobact...

journal_title：Infection and drug resistance

authors： Markovska R,Stoeva T,Dimitrova D,Boyanova L,Stankova P,Mihova K,Mitov I

更新日期：2019-05-28 00:00:00

abstract：Background:Bloodstream infection (BSI) caused by carbapenem-resistant Enterobacteriaceae are potentially life-threatening related to poorer outcomes. Colistin is considered one of the last-resort treatments against human infections caused by multidrug-resistant (MDR) Gram-negative bacteria. Therefore, emergence of stra...

journal_title：Infection and drug resistance

authors： Lin M,Yang Y,Yang Y,Chen G,He R,Wu Y,Zhong LL,El-Sayed Ahmed MAE,Feng S,Shen C,Wen X,Huang J,Li H,Zheng X,Tian GB

更新日期：2020-05-12 00:00:00

abstract：:Vancomycin has usually been associated with nephrotoxicity. Generally, this toxicity is presented as proximal tubular cells injury with or without necrosis and as acute interstitial nephritis. However, development of both lesions is uncommonly described in literature. We present a case of vancomycin-induced nephrotoxi...

journal_title：Infection and drug resistance

authors： Barceló-Vidal J,Rodríguez-García E,Grau S

更新日期：2018-07-30 00:00:00

abstract：Purpose:The aim of this work was to identify a novel β-lactamase gene blaPAU-1 encoded on the plasmid of a clinical Pseudomonas aeruginosa isolate. Materials and methods:The clinical P. aeruginosa isolates were isolated from a hospital in southern China. Molecular cloning was performed to analyze the function of the r...

journal_title：Infection and drug resistance

authors： Wang J,Xu T,Ying J,Zhou W,Chen Q,Qian C,Zhu X,Shen K,Li P,Li K,Bao Q,Lu J

更新日期：2019-12-05 00:00:00

abstract：BACKGROUND:Candida spp. are a frequent cause of nosocomial bloodstream infections worldwide. OBJECTIVE:To evaluate the use patterns and outcomes associated with intravenous (IV) fluconazole therapy in intensive care units in Spain and Germany. PATIENTS AND METHODS:The research reported here was a prospective multicen...

journal_title：Infection and drug resistance

authors： Wissing H,Ballus J,Bingold TM,Nocea G,Krobot KJ,Kaskel P,Kumar RN,Mavros P

更新日期：2013-01-01 00:00:00

abstract：:Raltegravir, an inhibitor of the HIV-1 integrase enzyme, is the first available agent in a new class of antiretroviral drugs. Raltegravir has been studied extensively in clinical trials, and has been well tolerated and highly effective in both treatment-naïve and -experienced patients. Resistance to raltegravir is unu...

journal_title：Infection and drug resistance

authors： Chirch LM,Steigbigel RT

更新日期：2010-01-01 00:00:00