Intensive care unit-related fluconazole use in Spain and Germany: patient characteristics and outcomes of a prospective multicenter longitudinal observational study.

abstract：:Tuberculosis remains the world's second leading infectious cause of death, with nearly one-third of the global population latently infected. Treatment of latent tuberculosis infection is a mainstay of tuberculosis-control efforts in low-to medium-incidence countries. Isoniazid monotherapy has been the standard of care...

journal_title：Infection and drug resistance

authors： Norton BL,Holland DP

更新日期：2012-01-01 00:00:00

abstract：Background:With an aging population, China is facing a huge burden of elderly patients with drug resistant tuberculosis (DR-TB), which has become a significant obstacle for the global TB control. There is still little study on DR-TB in the elderly in China so far. Thus, more research on the epidemiological characterist...

journal_title：Infection and drug resistance

authors： An Q,Song W,Liu J,Tao N,Liu Y,Zhang Q,Xu T,Li S,Liu S,Li Y,Yu C,Li H

更新日期：2020-11-13 00:00:00

abstract：Introduction:Schistosomiasis is an important neglected tropical disease (NTD) in several developing countries. Praziquantel is the principle and efficacious chemotherapeutic agent that has been used to treat schistosomiasis for decades. Unfortunately, emerging resistance to praziquantel with accompanying reduced effica...

journal_title：Infection and drug resistance

authors： El-Kady AM,El-Amir MI,Hassan MH,Allemailem KS,Almatroudi A,Ahmad AA

更新日期：2020-10-15 00:00:00

abstract：:Removal of the spleen had already been established as a routine technique to treat splenic trauma and other diseases affecting the spleen before the anatomy, physiology, and function of the spleen were known in the mid-twentieth century. It is now widely accepted that the splenectomized individual is at increased risk...

journal_title：Infection and drug resistance

authors： Luu S,Spelman D,Woolley IJ

更新日期：2019-09-12 00:00:00

abstract：OBJECTIVE:Many components of the immune system undergo adverse changes during intense physical activity in athletes, leading to a heightened risk of respiratory tract infections. This study evaluated the reduction in infectious processes in athletes due to intensive training with anapsos. METHODS:The study compared at...

journal_title：Infection and drug resistance

authors： Solivellas BM,Martín TC

更新日期：2012-01-01 00:00:00

abstract：Background:The timely and accurate diagnosis of infected nonunion is challenging, and there is a need for more efficient biomarkers. Previous studies have shown that fibrinogen plays an important role in mediating inflammation in bacterial infections and, therefore, could be a valuable biomarker for infected nonunion. ...

journal_title：Infection and drug resistance

authors： Wang XJ,Wang Z,Zhang ZT,Qiu XS,Chen M,Chen YX

更新日期：2020-11-04 00:00:00

abstract：BACKGROUND AND AIMS:Resistance mutation analogs to nucleos(t)ides have been described in treatment-naïve patients with chronic hepatitis B (CHB), with clinical implications. The aim of this study was to investigate primary resistance mutations and genotypes circulating in patients naïve to chronic hepatitis B, in the N...

journal_title：Infection and drug resistance

authors： Pacheco SR,Dos Santos MIMA,Stocker A,Zarife MAS,Schinoni MI,Paraná R,Dos Reis MG,Silva LK

更新日期：2017-07-05 00:00:00

abstract：:Background: The widespread use of antibiotics has resulted in a high incidence of antibiotic-associated diarrhea (AAD); moreover, the AAD-associated mortality rates have also increased. The effect of combined antibiotic administration on AAD in critically ill patients was analyzed to assist in antibiotic selection for...

journal_title：Infection and drug resistance

authors： Ma H,Zhang L,Zhang Y,Liu Y,He Y,Guo L

更新日期：2019-05-01 00:00:00

abstract：:Despite intensive efforts to eradicate the disease, tuberculosis continues to be a major threat to Indian society, with an estimated prevalence of 3.45 million cases in 2006. Emergence of multidrug-resistant tuberculosis has complicated eradication attempts in recent years. Incomplete and/inadequate treatment are the ...

journal_title：Infection and drug resistance

authors： Yashodhara BM,Huat CB,Naik LN,Umakanth S,Hande M,Pappachan JM

更新日期：2010-01-01 00:00:00

abstract：Purpose:This study aims to 1) describe the distribution characteristics of teicoplanin trough concentration (Cmin) and explore the related influencing factors and 2) evaluate the nephrotoxicity of teicoplanin in children. Patients and Methods:A cohort of children who were treated with teicoplanin intravenously were in...

journal_title：Infection and drug resistance

authors： Sun D,Zhang T,Mi J,Dong Y,Liu Y,Zhang Y,Zhang D,Wang T,Cheng H,Dong Y

更新日期：2020-11-12 00:00:00

abstract：Background:Flomoxef is potentially effective against β-lactamase-producing Enterobacteriaceae because limited clinical data demonstrate its effectiveness against Enterobacteriaceae bloodstream infections (BSIs) based on its minimum inhibitory concentrations (MICs). This study was conducted to determine the optimal brea...

journal_title：Infection and drug resistance

authors： Lee CH,Chen IL,Li CC,Chien CC

更新日期：2018-11-27 00:00:00

abstract：Introduction:Candida species, one among the opportunistic fungi, has become a common pathogen causing vaginal thrush and nosocomial bloodstream infections (BSIs). This study aims to evaluate the prevalence and antifungal susceptibility of various Candida species and slime production by Candida species in BSIs and vulvo...

journal_title：Infection and drug resistance

authors： Tulasidas S,Rao P,Bhat S,Manipura R

更新日期：2018-11-23 00:00:00

abstract：Purpose:To assess the efficacy of amoxicillin, tetracycline, high-dose metronidazole, and a proton-pump inhibitor for third-line Helicobacter pylori eradication. Methods:We enrolled 70 consecutive patients who had registered, failed to respond to two rounds of H. pylori eradication, and undergone endoscopy for H. pylo...

journal_title：Infection and drug resistance

authors： Huang HT,Wang HM,Yang SC,Tai WC,Liang CM,Wu KL,Lee CH,Chuah SK

更新日期：2018-10-30 00:00:00

abstract：:While methicillin-resistant Staphylococcus aureus (MRSA) bacteremia has poor outcomes, we describe our experience with Ceftobiprole mainly as a combination therapy for the treatment of MRSA bacteremia. All the cases of MRSA bacteremia in our center at the King Abdulaziz Medical City (KAMC), Riyadh, that had undergone ...

journal_title：Infection and drug resistance

authors： Mahmoud E,Al Mansour S,Bosaeed M,Alharbi A,Alsaedy A,Aljohani S,Alalwan B,Alothman A

更新日期：2020-08-03 00:00:00

abstract：Background:Acinetobacter baumannii has emerged as an important pathogen associated with hospital- and community-acquired infections. Community-acquired A. baumannii pneumonia is characterized by a fulminant course and high mortality rates. In this study, we report the identification of a community-acquired carbapenem-r...

journal_title：Infection and drug resistance

authors： Jia H,Sun Q,Ruan Z,Xie X

更新日期：2019-06-06 00:00:00

abstract：:Aspergillus endocarditis (AE) accounts for a-quarter of all fungal endocarditis, mainly in immunocompromised hosts prior to heart-valve surgery with high mortality, even with treatment. Herein, we report a rare case of AE in a diabetic 60-year-old woman with a history of redo mitral valve prosthesis suspecious of acut...

journal_title：Infection and drug resistance

authors： Jalalian R,Shokohi T,Mirzakhani R,Ghasemian R,Hedayati MT,Ardalani S,Azizi S,Kalhori S,Kermani F,Mayahi S

更新日期：2020-07-10 00:00:00

abstract：Purpose:To develop a rapid EDTA-modified carbapenem inactivation method (reCIM) combined with modified rapid carbapenem inactivation method (mrCIM) to detect carbapenemase and distinguish metallo-β-lactamases from carbapenemases in Enterobacteriaceae in 4 hrs. Materials and Methods:The sensitivities and specificities ...

journal_title：Infection and drug resistance

authors： Wei Q,Sun J,Wang Z,Yan L,Zhang C,Xu X

更新日期：2020-06-23 00:00:00

abstract：Background:Colistin acts as the last line of defense against severe infections caused by carbapenem-resistant Enterobacteriaceae. Infections caused by extensively drug-resistant isolates coproducing MCR and carbapenemases have posed a serious public health concern. Purpose:In this study, we reported the first clinical...

journal_title：Infection and drug resistance

authors： Yuan Y,Li Y,Wang G,Li C,Xiang L,She J,Yang Y,Zhong F,Zhang L

更新日期：2019-09-19 00:00:00

abstract：:Purpose: The aim of this study was to use a network meta-analysis to evaluate the relative efficacy of various agents at preventing invasive fungal infections (IFIs). In this way, suitable prophylactic regimens may be selected for patients with hematopoietic stem cell transplantation (HSCT). Methods: We conducted a sy...

journal_title：Infection and drug resistance

authors： Su HC,Hua YM,Feng IJ,Wu HC

更新日期：2019-05-15 00:00:00

abstract：Introduction:Duodenoscopes have been widely used for both diagnostic and therapeutic endoscopic retrograde cholangiopancreatography procedures. Numerous outbreaks of duodenoscope-associated infections involving multidrug-resistant bacteria have recently been reported. Plasma activated water (PAW) has been widely consid...

journal_title：Infection and drug resistance

authors： Bălan GG,Roşca I,Ursu EL,Doroftei F,Bostănaru AC,Hnatiuc E,Năstasă V,Şandru V,Ştefănescu G,Trifan A,Mareş M

更新日期：2018-05-17 00:00:00

abstract：Background:The incidence of human papilloma virus (HPV) infections in conservative populations is increasing, yet vaccination is not routinely recommended by primary health care (PHC) physicians. The aim of this study is to evaluate PHC physicians' awareness of HPV infections and vaccination in Saudi Arabia. Materials...

journal_title：Infection and drug resistance

authors： Almughais ES,Alfarhan A,Salam M

更新日期：2018-11-15 00:00:00

abstract：Background:The aim of this study was to evaluate the clinical performance of the BD Kiestra InoqulA automated specimen processing system with commonly encountered clinical microbiology specimens. Materials and Methods:Four types of clinical specimens (sputum, urine, normally sterile body fluids, and feces) were inocul...

journal_title：Infection and drug resistance

authors： Yue P,Zhou M,Zhang L,Yang Q,Song H,Xu Z,Zhang G,Xie X,Xu Y

更新日期：2020-04-01 00:00:00

abstract：Objective:To provide a comprehensive review of vancomycin dosing in patients with hematologic malignancies or neutropenia. Methods:PubMed, Embase and the Cochrane Library were searched through April 2, 2020. Original studies relevant to vancomycin dosing regimen in adults with hematologic malignancies or neutropenia w...

journal_title：Infection and drug resistance

authors： He N,Dong F,Liu W,Zhai S

更新日期：2020-06-16 00:00:00

abstract：:COVID-19 is an emerging disease all over the world and spreading at an unpredicted rate, resulting in significant influences on global economies and public health. Clinical, laboratory, and imaging characteristics have been partially described in some observational studies. Not enough systematic reviews on predictors ...

journal_title：Infection and drug resistance

authors： Aly MH,Rahman SS,Ahmed WA,Alghamedi MH,Al Shehri AA,Alkalkami AM,Hassan MH

更新日期：2020-06-26 00:00:00

abstract：Objective:An ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method for the determination of selinexor was established to investigate the effects of isavuconazole, itraconazole and fluconazole on the pharmacokinetics of selinexor in rats, respectively. Methods:Twenty-four healthy male rat...

journal_title：Infection and drug resistance

authors： Li SL,Zhang Y,Cheng QS,Xin JZ,Dong ZQ,Qiu XJ

更新日期：2020-09-14 00:00:00

abstract：:The increase in hospitalization due to acute bacterial skin and skin structure infections (ABSSSI) caused by resistant pathogens supports the need for new treatment options. Antimicrobial options for ABSSSI that provide broad-spectrum coverage, including gram-negative pathogens and multidrug-resistant gram-positive ba...

journal_title：Infection and drug resistance

authors： Righi E,Carnelutti A,Vena A,Bassetti M

更新日期：2018-04-04 00:00:00

abstract：:Echinocandin antifungal agents have become the first-line therapy for invasive candidiasis (IC) in many countries. Despite their increasing use, resistance to this class of drug is, overall, still uncommon. Here, we report two patients from the People's Republic of China with IC, one with infection caused by pan-echin...

journal_title：Infection and drug resistance

authors： Xiao M,Fan X,Hou X,Chen SC,Wang H,Kong F,Sun ZY,Chu YZ,Xu YC

更新日期：2018-01-23 00:00:00

abstract：Background:The emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) resulted in a worldwide devastating effect with a diagnostic challenge. Identifying risk factors of severity aids in assessment for the need of early hospitalization. We aimed to demonstrate, for the first time, the clinical, laborator...

journal_title：Infection and drug resistance

authors： Ramadan HK,Mahmoud MA,Aburahma MZ,Elkhawaga AA,El-Mokhtar MA,Sayed IM,Hosni A,Hassany SM,Medhat MA

更新日期：2020-10-05 00:00:00

abstract：Introduction:Trichophyton mentagrophytes and T. interdigitale are important causative agents of superficial mycoses, demonstrating emergent antifungal drug resistance. We studied the antifungal susceptibility profiles in Iranian isolates of these two species. Methods:A total of 96 T. interdigitale and 45 T. mentagroph...

journal_title：Infection and drug resistance

authors： Taghipour S,Shamsizadeh F,Pchelin IM,Rezaei-Matehhkolaei A,Zarei Mahmoudabadi A,Valadan R,Ansari S,Katiraee F,Pakshir K,Zomorodian K,Abastabar M

更新日期：2020-03-13 00:00:00

abstract：Background:Recurrent tuberculosis (TB) following TB treatment completion in HIV-infected individuals remains a major public health burden. We assessed the role of various risk factors in mediating the development of recurrent TB and subsequent resistance to antiretroviral therapy and anti-TB drugs. Patients and method...

journal_title：Infection and drug resistance

authors： Naidoo K,Dookie N,Naidoo K,Yende-Zuma N,Chimukangara B,Bhushan A,Govender D,Gengiah S,Padayatchi N

更新日期：2018-09-05 00:00:00