Exploring bacterial outer membrane barrier to combat bad bugs.

abstract：Background:Ethiopia is one of the 22 high tuberculosis burden countries. In our country. there are limited published data to show the trend analysis of tuberculosis. Hence, we designed this trend analysis to fill the information gap in our study area. Institutional based retrospective cross-sectional study was employed...

journal_title：Infection and drug resistance

authors： Negash H,Legese H,Adhanom G,Mardu F,Tesfay K,Gebreslasie Gebremeskel S,Berhe B

更新日期：2020-02-24 00:00:00

abstract：Background:Broad-scale evidence has shown the significant association between ambient air pollutants and the development of tuberculosis (TB). However, the impact of air quality on the risk of TB in Taiwan is still poorly understood. Objective:To develop a probabilistic integrated population-level risk assessment appr...

journal_title：Infection and drug resistance

authors： Lin YJ,Lin HC,Yang YF,Chen CY,Ling MP,Chen SC,Chen WY,You SH,Lu TH,Liao CM

更新日期：2019-12-06 00:00:00

abstract：Purpose:To characterize the genetic feature of the carbapenems resistant Acinetobacter johnsonii strain Acsw19 isolated from municipal sludge. This strain was found to carry two copies of blaNDM-1,cmlB1-like gene, and blaOXA-211-like gene along with other 8 antimicrobial resistance genes, 3 plasmids, 15 genomic islands...

journal_title：Infection and drug resistance

authors： Tang L,Shen W,Zhang Z,Zhang J,Wang G,Xiang L,She J,Hu X,Zou G,Zhu B,Zhou Y

更新日期：2020-03-23 00:00:00

abstract：Background:The aim of this study was to evaluate the clinical performance of the BD Kiestra InoqulA automated specimen processing system with commonly encountered clinical microbiology specimens. Materials and Methods:Four types of clinical specimens (sputum, urine, normally sterile body fluids, and feces) were inocul...

journal_title：Infection and drug resistance

authors： Yue P,Zhou M,Zhang L,Yang Q,Song H,Xu Z,Zhang G,Xie X,Xu Y

更新日期：2020-04-01 00:00:00

abstract：Background:Streptococcus pneumoniae is an important pathogen in chronic obstructive pulmonary disease (COPD). We aimed at showing the recent changes in the epidemiology of pneumococcal diseases in patients with COPD, especially after the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13). Methods:Fro...

journal_title：Infection and drug resistance

authors： Shoji H,Vázquez-Sánchez DA,Gonzalez-Diaz A,Cubero M,Tubau F,Santos S,García-Somoza D,Liñares J,Yuste J,Martí S,Ardanuy C

更新日期：2018-09-04 00:00:00

abstract：Background:Colistin acts as the last line of defense against severe infections caused by carbapenem-resistant Enterobacteriaceae. Infections caused by extensively drug-resistant isolates coproducing MCR and carbapenemases have posed a serious public health concern. Purpose:In this study, we reported the first clinical...

journal_title：Infection and drug resistance

authors： Yuan Y,Li Y,Wang G,Li C,Xiang L,She J,Yang Y,Zhong F,Zhang L

更新日期：2019-09-19 00:00:00

abstract：:Background: The widespread use of antibiotics has resulted in a high incidence of antibiotic-associated diarrhea (AAD); moreover, the AAD-associated mortality rates have also increased. The effect of combined antibiotic administration on AAD in critically ill patients was analyzed to assist in antibiotic selection for...

journal_title：Infection and drug resistance

authors： Ma H,Zhang L,Zhang Y,Liu Y,He Y,Guo L

更新日期：2019-05-01 00:00:00

abstract：Background:Tachyplesin I is a cationic antimicrobial peptide with a typical cyclic antiparallel β-sheet structure. We previously demonstrated that long-term continuous exposure to increased concentration of tachyplesin I can induce resistant Gram-negative bacteria. However, no significant information is available about...

journal_title：Infection and drug resistance

authors： Hong J,Jiang H,Hu J,Wang L,Liu R

更新日期：2020-01-16 00:00:00

abstract：:Streptococcus pneumonia is a rare cause of pyogenic sacroiliitis and osteomyelitis. A case of pneumococcal sacroiliitis and osteomyelitis is reported herein. The patient was a previously healthy 54-year-old man with a 3-day history of fever and a 3-week history of increasing right-side thigh pain. Computed tomography ...

journal_title：Infection and drug resistance

authors： Hadano Y,Chang B

更新日期：2018-08-03 00:00:00

abstract：:The rapid detection of carbapenemase allows implementation of infection control measures and adaptation of antibiotic therapy. We evaluated the performances of the Xpert Carba-R V2® assay for the direct detection and identification of carbapenemase on positive blood cultures. We focused our evaluation on its detection...

journal_title：Infection and drug resistance

authors： Cointe A,Walewski V,Hobson CA,Doit C,Bidet P,Dortet L,Bonacorsi S,Birgy A

更新日期：2019-10-23 00:00:00

abstract：Purpose:This research aimed to investigate the antibacterial activity and potential mechanism of luteolin against T. pyogenes. Materials and Methods:The broth microdilution method was used to determine the minimum inhibitory concentrations (MICs) of luteolin against various T. pyogenes strains. The potential mechanism...

journal_title：Infection and drug resistance

authors： Guo Y,Liu Y,Zhang Z,Chen M,Zhang D,Tian C,Liu M,Jiang G

更新日期：2020-06-10 00:00:00

abstract：Purpose:To investigate the occurrence and genetic characteristics of the blaIMP-26-positive plasmid from a multidrug-resistant clinical isolate, Enterobacter hormaechei L51. Methods:Species identification was determined by MALDI-TOF MS and Sanger sequencing. Antimicrobial susceptibility testing was performed by the ag...

journal_title：Infection and drug resistance

authors： Gou JJ,Liu N,Guo LH,Xu H,Lv T,Yu X,Chen YB,Guo XB,Rao YT,Zheng BW

更新日期：2020-02-20 00:00:00

abstract：:Genetic and cellular studies have shown that the host's innate and adaptive immune responses are an important correlate of viral infection outcome. The features of the host's immune response (host resistance) reflect the coevolution between hosts and pathogens that has occurred over millennia, and that has also result...

journal_title：Infection and drug resistance

authors： Plauzolles A,Lucas M,Gaudieri S

更新日期：2015-04-07 00:00:00

abstract：Purpose:The activity of the cationic antimicrobial peptide WLBU2 was evaluated against planktonic cells and biofilms of multi-drug resistant (MDR) Acinetobacter baumannii and Klebsiella pneumoniae, alone and in combination with classical antimicrobial agents. Methods:Control American Type Culture Collection (ATCC) str...

journal_title：Infection and drug resistance

authors： Swedan S,Shubair Z,Almaaytah A

更新日期：2019-07-09 00:00:00

abstract：Introduction:Management of ventilator-associated pneumonia (VAP), the most common infection in patients on mechanical ventilation, should be tailored to local microbiological data. The aim of this study was to determine susceptibility patterns of organisms causing VAP to develop a treatment algorithm based on these fin...

journal_title：Infection and drug resistance

authors： Awad LS,Abdallah DI,Mugharbil AM,Jisr TH,Droubi NS,El-Rajab NA,Moghnieh RA

更新日期：2017-12-22 00:00:00

abstract：Background and Objectives:Tuberculosis (TB) is a global public health issue. The emergence of multidrug-resistant (MDR) TB has further complicated the situation in the form of poor treatment outcomes and costs to individuals and health-care systems. We therefore aimed to measure the prevalence and associated risk facto...

journal_title：Infection and drug resistance

authors： Sambas MFMK,Rabbani U,Al-Gethamy MMM,Surbaya SH,Alharbi FFI,Ahmad RGA,Qul HKH,Nassar SMS,Maddah AKMA,Darweesh BAK

更新日期：2020-11-10 00:00:00

abstract：:We present here the first report of an OXA-181-producing Klebsiella pneumoniae isolated from the fecal specimen of a patient in China. The OXA-181-encoding gene blaOXA-181 was located on a 51 kb IncX3-type plasmid. Conjugation assay and whole-genome sequencing analysis revealed that this transferrable plasmid in the K...

journal_title：Infection and drug resistance

authors： Liu C,Fang Y,Zeng Y,Lu J,Sun Q,Zhou H,Shen Z,Chen G

更新日期：2020-04-06 00:00:00

abstract：Purpose:The aim was to examine the clinical characteristics and risk factors for bloodstream infection (BSI) due to carbapenem-resistant Klebsiella pneumoniae (CRKP) in patients with hematologic malignancies. Materials and Methods:A single-centre, retrospective case-control study representing 734 patients with hematol...

journal_title：Infection and drug resistance

authors： Zhang P,Wang J,Hu H,Zhang S,Wei J,Yang Q,Qu T

更新日期：2020-09-22 00:00:00

abstract：Background:Acinetobacter baumannii has emerged as an important pathogen associated with hospital- and community-acquired infections. Community-acquired A. baumannii pneumonia is characterized by a fulminant course and high mortality rates. In this study, we report the identification of a community-acquired carbapenem-r...

journal_title：Infection and drug resistance

authors： Jia H,Sun Q,Ruan Z,Xie X

更新日期：2019-06-06 00:00:00

abstract：Introduction:Duodenoscopes have been widely used for both diagnostic and therapeutic endoscopic retrograde cholangiopancreatography procedures. Numerous outbreaks of duodenoscope-associated infections involving multidrug-resistant bacteria have recently been reported. Plasma activated water (PAW) has been widely consid...

journal_title：Infection and drug resistance

authors： Bălan GG,Roşca I,Ursu EL,Doroftei F,Bostănaru AC,Hnatiuc E,Năstasă V,Şandru V,Ştefănescu G,Trifan A,Mareş M

更新日期：2018-05-17 00:00:00

abstract：Background:Bloodstream infection (BSI) caused by carbapenem-resistant Enterobacteriaceae are potentially life-threatening related to poorer outcomes. Colistin is considered one of the last-resort treatments against human infections caused by multidrug-resistant (MDR) Gram-negative bacteria. Therefore, emergence of stra...

journal_title：Infection and drug resistance

authors： Lin M,Yang Y,Yang Y,Chen G,He R,Wu Y,Zhong LL,El-Sayed Ahmed MAE,Feng S,Shen C,Wen X,Huang J,Li H,Zheng X,Tian GB

更新日期：2020-05-12 00:00:00

abstract：:Vancomycin has usually been associated with nephrotoxicity. Generally, this toxicity is presented as proximal tubular cells injury with or without necrosis and as acute interstitial nephritis. However, development of both lesions is uncommonly described in literature. We present a case of vancomycin-induced nephrotoxi...

journal_title：Infection and drug resistance

authors： Barceló-Vidal J,Rodríguez-García E,Grau S

更新日期：2018-07-30 00:00:00

abstract：:Purpose: The aim of this study was to use a network meta-analysis to evaluate the relative efficacy of various agents at preventing invasive fungal infections (IFIs). In this way, suitable prophylactic regimens may be selected for patients with hematopoietic stem cell transplantation (HSCT). Methods: We conducted a sy...

journal_title：Infection and drug resistance

authors： Su HC,Hua YM,Feng IJ,Wu HC

更新日期：2019-05-15 00:00:00

abstract：:Raltegravir, an inhibitor of the HIV-1 integrase enzyme, is the first available agent in a new class of antiretroviral drugs. Raltegravir has been studied extensively in clinical trials, and has been well tolerated and highly effective in both treatment-naïve and -experienced patients. Resistance to raltegravir is unu...

journal_title：Infection and drug resistance

authors： Chirch LM,Steigbigel RT

更新日期：2010-01-01 00:00:00

abstract：:Despite intensive efforts to eradicate the disease, tuberculosis continues to be a major threat to Indian society, with an estimated prevalence of 3.45 million cases in 2006. Emergence of multidrug-resistant tuberculosis has complicated eradication attempts in recent years. Incomplete and/inadequate treatment are the ...

journal_title：Infection and drug resistance

authors： Yashodhara BM,Huat CB,Naik LN,Umakanth S,Hande M,Pappachan JM

更新日期：2010-01-01 00:00:00

abstract：Introduction:Candida species, one among the opportunistic fungi, has become a common pathogen causing vaginal thrush and nosocomial bloodstream infections (BSIs). This study aims to evaluate the prevalence and antifungal susceptibility of various Candida species and slime production by Candida species in BSIs and vulvo...

journal_title：Infection and drug resistance

authors： Tulasidas S,Rao P,Bhat S,Manipura R

更新日期：2018-11-23 00:00:00

abstract：Background:Hepatitis E virus (HEV) is an emerging infectious agent that causes acute hepatitis in developing and developed countries. Diagnosis of HEV infection has not been routinely done in Egyptian hospitals, and clinicians do not prescribe ribavirin (RBV) for acute hepatitis cases of unknown etiology (AHUE). We aim...

journal_title：Infection and drug resistance

authors： Sayed IM,El-Mokhtar MA,Mahmoud MAR,Elkhawaga AA,Gaber S,Seddek NH,Abdel-Wahid L,Ashmawy AM,Alkareemy EAR

更新日期：2021-01-12 00:00:00

abstract：:Lucio's phenomenon (LP) is a special reactional state associated with diffuse multibacillary leprosy; both exhibit a limitative global distribution mainly in Mexico and Central America. We report a case of a 28-year-old female leprosy patient in the People's Republic of China, together with LP and positive anticardiol...

journal_title：Infection and drug resistance

authors： Gao W,Chen Z,Jiang H,Shi Y,Zhang W,Wang H

更新日期：2019-04-02 00:00:00

abstract：OBJECTIVES:Stenotrophomonas maltophilia shows wide-spectrum resistance to antimicrobials and causes various infections in immunocompromised or critically ill patients with high mortality. In this era of antibiotics resistance, a revival of old antibiotics is now featured. We examined the clinical usefulness of latamoxe...

journal_title：Infection and drug resistance

authors： Hagiya H,Tasaka K,Sendo T,Otsuka F

更新日期：2015-10-20 00:00:00

abstract：Purpose:Respiratory viruses are important etiologies of community-acquired pneumonia (CAP). However, the impact of different RVs on the outcomes of CAP is not well elucidated. This study aims to compare the clinical features and severity of influenza (Flu-p) and non-influenza respiratory viruses-related pneumonia (NIRV...

journal_title：Infection and drug resistance

authors： Chen L,Han XD,Li YL,Zhang CX,Xing XQ

更新日期：2020-10-08 00:00:00