Abstract：
:Sweet taste receptors are composed of a heterodimer of taste 1 receptor member 2 (T1R2) and taste 1 receptor member 3 (T1R3). Accumulating evidence shows that sweet taste receptors are ubiquitous throughout the body, including in the gastrointestinal tract as well as the hypothalamus. These sweet taste receptors are heavily involved in nutrient sensing, monitoring changes in energy stores, and triggering metabolic and behavioral responses to maintain energy balance. Not surprisingly, these pathways are heavily regulated by external and internal factors. Dysfunction in one or more of these pathways may be important in the pathogenesis of common diseases, such as obesity and type 2 diabetes mellitus.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Lee AA,Owyang Cdoi
10.3390/nu9070653subject
Has Abstractpub_date
2017-06-24 00:00:00issue
7issn
2072-6643pii
nu9070653journal_volume
9pub_type
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