Malaria ecology along the Thailand-Myanmar border.

abstract：BACKGROUND:In areas with ongoing malaria transmission, strategies to clear parasites from populations can reduce infection and transmission. The objective of this paper was to describe a malaria mass testing and treatment (MTAT) intervention implemented in six kebeles (villages) in Amhara Region, Ethiopia, at the begin...

journal_title：Malaria journal

authors： Scott CA,Yeshiwondim AK,Serda B,Guinovart C,Tesfay BH,Agmas A,Zeleke MT,Guesses GS,Ayenew AL,Workie WM,Steketee RW,Earle D,Bezabih B,Getachew A

更新日期：2016-06-02 00:00:00

abstract：BACKGROUND:Congenital malaria is the direct infection of an infant with malaria parasites from their mother prior to or during birth. Neonatal malaria is due to an infective mosquito bite after birth. Neonatal and congenital malaria (NCM) are potentially life-threatening conditions that are believed to occur at relativ...

journal_title：Malaria journal

authors： Olupot-Olupot P,Eregu EIE,Naizuli K,Ikiror J,Acom L,Burgoine K

更新日期：2018-04-20 00:00:00

abstract：BACKGROUND:It was unknown whether the main reservoir of Plasmodium falciparum and Plasmodium vivax, which infects mosquitoes in Thailand, was (a) in people feeling sufficiently ill with malaria to come to a clinic or (b) in people who had remained in their home villages with some fever symptoms or with none. METHODS:M...

journal_title：Malaria journal

authors： Pethleart A,Prajakwong S,Suwonkerd W,Corthong B,Webber R,Curtis C

更新日期：2004-09-22 00:00:00

abstract：BACKGROUND:Within the context of combined interventions, malaria vaccine may provide additional value in malaria prevention. Stakeholders' perspectives are thus critical for informed recommendation of the vaccine in Tanzania. This paper presents the views of stakeholders with regards to malaria vaccine in 12 Tanzanian ...

journal_title：Malaria journal

authors： Mtenga S,Kimweri A,Romore I,Ali A,Exavery A,Sicuri E,Tanner M,Abdulla S,Lusingu J,Kafuruki S

更新日期：2016-04-05 00:00:00

abstract：BACKGROUND:Recent progress in malaria control has caused renewed interest in mass drug administration (MDA) as a potential elimination strategy but the evidence base is limited. China has extensive experience with MDA, but it is not well documented. METHODS:An ecological study was conducted to describe the use of MDA ...

journal_title：Malaria journal

authors： Hsiang MS,Hwang J,Tao AR,Liu Y,Bennett A,Shanks GD,Cao J,Kachur SP,Feachem RG,Gosling RD,Gao Q

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Kohat district is one of the medium intensity malaria transmission areas in Pakistan where asymptomatic carriers are likely to form a reservoir of infection. This study was done to explore the possibility of using microscopy, rapid diagnostic testing (RDT), real time polymerase chain reaction (RT-PCR) and RT...

journal_title：Malaria journal

authors： Naeem MA,Ahmed S,Khan SA

更新日期：2018-01-22 00:00:00

abstract：BACKGROUND:Environmental temperature is an important driver of malaria transmission dynamics. Both the parasite and vector are sensitive to mean ambient temperatures and daily temperature variation. To understand transmission ecology, therefore, it is important to determine the range of microclimatic temperatures exper...

journal_title：Malaria journal

authors： Cator LJ,Thomas S,Paaijmans KP,Ravishankaran S,Justin JA,Mathai MT,Read AF,Thomas MB,Eapen A

更新日期：2013-03-02 00:00:00

abstract：BACKGROUND:Anti-malarial herbal preparations (HPs) continue to enjoy high patronage in Ghana despite reports that the artemisinin-based combination therapy (ACT), the recommended first choice for treatment of uncomplicated malaria in the country, remains efficacious. A major issue with the use of these preparations is ...

journal_title：Malaria journal

authors： Wilmot D,Ameyaw EO,Amoako-Sakyi D,Boampong JN,Quashie NB

更新日期：2017-03-04 00:00:00

abstract：BACKGROUND:The sulphadoxine/pyrimethamine (SDX/PYR) combination had been chosen to treat uncomplicated falciparum malaria in Malaysia for more than 30 years. Non-silent mutations in dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) genes are responsible for the resistance to pyrimethamine and sulphadox...

journal_title：Malaria journal

authors： Lau TY,Sylvi M,William T

更新日期：2013-12-10 00:00:00

abstract：BACKGROUND:The zoonotic malaria parasite Plasmodium knowlesi has become an emerging threat to South East Asian countries particular in Malaysia. A recent study from Sarawak (Malaysian Borneo) discovered two distinct normocyte binding protein xa (Pknbpxa) types of P. knowlesi. In the present study, the Pknbpxa of clinic...

journal_title：Malaria journal

authors： Ahmed MA,Fong MY,Lau YL,Yusof R

更新日期：2016-04-26 00:00:00

abstract：BACKGROUND:Polymorphism in the pfcrt gene underlies Plasmodium falciparum chloroquine resistance (CQR), as sensitive strains consistently carry lysine (K), while CQR strains carry threonine (T) at the codon 76. Previous studies have shown that microsatellite (MS) haplotype variation can be used to study the evolution o...

journal_title：Malaria journal

authors： DaRe JT,Mehlotra RK,Michon P,Mueller I,Reeder J,Sharma YD,Stoneking M,Zimmerman PA

更新日期：2007-03-21 00:00:00

abstract：BACKGROUND:Antiplasmodial activities of angiotensin II and its analogues have been extensively investigated in Plasmodium gallinaceum and Plasmodium falciparum parasite species. Due to its vasoconstrictor property angiotensin II cannot be used as an anti-malarial drug. METHODS:This work presents the solid-phase synthe...

journal_title：Malaria journal

authors： Silva AF,Torres MD,Silva Lde S,Alves FL,Pinheiro AA,Miranda A,Capurro ML,Oliveira VX Jr

更新日期：2015-11-04 00:00:00

abstract：BACKGROUND:Malaria is a major public health problem in endemic countries including Sudan, where about 75% of populations are at risk. Due to widespread of chloroquine-resistant strains of Plasmodium falciparum, artemisinin-based combination therapy (ACT) is currently treatment of choice for malaria in the vast majority...

journal_title：Malaria journal

authors： Adam I,Ibrahim Y,Gasim GI

更新日期：2018-03-13 00:00:00

abstract：BACKGROUND:A malaria vaccine based on Plasmodium falciparum apical membrane antigen 1 (AMA1) elicited strain specific efficacy in Malian children that waned in the second season after vaccination despite sustained AMA1 antibody titers. With the goal of identifying a humoral correlate of vaccine-induced protection, pre-...

journal_title：Malaria journal

authors： Berry AA,Gottlieb ER,Kouriba B,Diarra I,Thera MA,Dutta S,Coulibaly D,Ouattara A,Niangaly A,Kone AK,Traore K,Tolo Y,Mishcherkin V,Soisson L,Diggs CL,Blackwelder WC,Laurens MB,Sztein MB,Doumbo OK,Plowe CV,Lyke KE

更新日期：2019-01-18 00:00:00

abstract：BACKGROUND:Intermittent preventive (or presumptive) treatment of infants (IPTi), the administration of a curative anti-malarial dose to infants whether or not they are known to be infected, is being considered as a new strategy for malaria control. Five of the six trials using sulphadoxine-pyrimethamine (SP) for IPTi s...

journal_title：Malaria journal

authors： Gosling RD,Ghani AC,Deen JL,von Seidlein L,Greenwood BM,Chandramohan D

更新日期：2008-04-03 00:00:00

abstract：BACKGROUND:Understanding the dynamics of malaria transmission in diverse endemic settings is key for designing and implementing locally adapted and sustainable control and elimination strategies. A parasitological and epidemiological survey was conducted in September-October 2012, as a baseline underlying a 3-year popu...

journal_title：Malaria journal

authors： Rosas-Aguirre A,Guzman-Guzman M,Gamboa D,Chuquiyauri R,Ramirez R,Manrique P,Carrasco-Escobar G,Puemape C,Llanos-Cuentas A,Vinetz JM

更新日期：2017-08-04 00:00:00

abstract：BACKGROUND:In many low-income countries, the private commercial sector plays an important role in the provision of malaria treatment. However, the quality of care it provides is often poor, with artemisinin combination therapy (ACT) generally being too costly for consumers. Decreasing ACT prices is critical for improvi...

journal_title：Malaria journal

authors： Patouillard E,Hanson K,Kleinschmidt I,Palafox B,Tougher S,Pok S,O'Connell K,Goodman C

更新日期：2015-05-30 00:00:00

abstract：BACKGROUND:This study was designed to evaluate the efficacy of exchange transfusion in patients with severe imported falciparum malaria. Twelve patients who met the diagnostic criteria for severe malaria were treated with exchange transfusion 14 times according to a conventional anti-malarial treatment. This study eval...

journal_title：Malaria journal

authors： Lin J,Huang X,Qin G,Zhang S,Sun W,Wang Y,Ren K,Xu J,Han X

更新日期：2018-01-16 00:00:00

abstract：BACKGROUND:Drug combination therapy is the frontline of malaria treatment. There is an ever-accelerating need for new, efficacious combination therapies active against drug resistant malaria. Proven drugs already in the treatment pipeline, such as the quinolines, are important components of current combination therapy ...

journal_title：Malaria journal

authors： Gorka AP,Jacobs LM,Roepe PD

更新日期：2013-09-18 00:00:00

abstract：BACKGROUND:Over the past several years, thousands of microRNAs (miRNAs) have been identified in the genomes of various insects through cloning and sequencing or even by computational prediction. However, the number of miRNAs identified in anopheline species is low and little is known about their role. The mosquito Anop...

journal_title：Malaria journal

authors： Allam M,Spillings BL,Abdalla H,Mapiye D,Koekemoer LL,Christoffels A

更新日期：2016-11-08 00:00:00

abstract：BACKGROUND:Thrombocytopaenia is the most frequent malaria-associated haematologic alteration observed with all five Plasmodium parasites causing disease in humans. Although not included in the World Health Organization criteria for severe Plasmodium falciparum malaria, severe thrombocytopaenia has been increasingly men...

journal_title：Malaria journal

authors： Antinori S,Corona A,Ridolfo AL,Galimberti L,Ricaboni D,Milazzo L,Corbellino M

更新日期：2016-02-19 00:00:00

abstract：BACKGROUND:Although chemoprophylaxis remains an important strategy for preventing malaria in travellers, its effectiveness may be compromised by lack of adherence. Inappropriate use of chemoprophylaxis is likely to increase the risk of acquiring malaria, but may probably also worsen the severity of imported cases. The ...

journal_title：Malaria journal

authors： Vliegenthart-Jongbloed K,de Mendonça Melo M,van Wolfswinkel ME,Koelewijn R,van Hellemond JJ,van Genderen PJ

更新日期：2013-07-31 00:00:00

abstract：:This meeting report presents the key findings and discussion points of a 1-day meeting entitled 'Fake anti-malarials: start with the facts' held on 28th May 2015, in Geneva, Switzerland, to disseminate the findings of the artemisinin combination therapy consortium's drug quality programme. The teams purchased over 10,...

journal_title：Malaria journal

authors： Kaur H,Clarke S,Lalani M,Phanouvong S,Guérin P,McLoughlin A,Wilson BK,Deats M,Plançon A,Hopkins H,Miranda D,Schellenberg D

更新日期：2016-02-13 00:00:00

abstract：BACKGROUND:Several public health interventions to improve management of patients with fever are largely focused on the public sector yet a high proportion of patients seek care outside the formal healthcare sector. Few studies have provided information on the determinants of utilization of the private sector as against...

journal_title：Malaria journal

authors： Ansah EK,Gyapong M,Narh-Bana S,Bart-Plange C,Whitty CJ

更新日期：2016-05-25 00:00:00

abstract：BACKGROUND:The merozoite surface protein 1 (msp1) is one of the most studied vaccine candidate genes in mammalian Plasmodium spp. to have been used for investigations of epidemiology, population structures, and immunity to infections. However methodological difficulties have impeded the use of nuclear markers such as m...

journal_title：Malaria journal

authors： Hellgren O,Kutzer M,Bensch S,Valkiūnas G,Palinauskas V

更新日期：2013-10-30 00:00:00

abstract：BACKGROUND:Following the recognition that morbidity and mortality due to malaria had dramatically increased in the last three decades, in 2002 the government of Zambia reviewed its efforts to prevent and treat malaria. Convincing evidence of the failing efficacy of chloroquine resulted in the initiation of a process th...

journal_title：Malaria journal

authors： Sipilanyambe N,Simon JL,Chanda P,Olumese P,Snow RW,Hamer DH

更新日期：2008-01-29 00:00:00

abstract：BACKGROUND:In children with malaria caused by Plasmodium falciparum, quinine administered rectally may be easier to use and less painful than intramuscular or intravenous administration. The objective of this review was to compare the effectiveness of intrarectal with intravenous or intramuscular quinine for treating f...

journal_title：Malaria journal

authors： Eisenhut M,Omari A,MacLehose HG

更新日期：2005-05-18 00:00:00

abstract：BACKGROUND:Private sector availability and use of malaria rapid diagnostic tests (RDTs) lags behind the public sector in Kenya. Increasing channels through which quality malaria diagnostic services are available can improve access to testing and help meet the target of universal diagnostic testing. Registered pharmacie...

journal_title：Malaria journal

authors： Poyer S,Musuva A,Njoki N,Okara R,Cutherell A,Sievers D,Lussiana C,Memusi D,Kiptui R,Ejersa W,Dolan S,Charman N

更新日期：2018-03-13 00:00:00

abstract：BACKGROUND:Polyclonal B-cell activation is well known to occur in Plasmodium infections, but its role in pathogenesis or protection remains unclear. However, protective properties of natural antibodies have previously been demonstrated in other contexts. METHODS:Sera from asymptomatic and symptomatic Plasmodium-infect...

journal_title：Malaria journal

authors： Fesel C,Goulart LF,Silva Neto A,Coelho A,Fontes CJ,Braga EM,Vaz NM

更新日期：2005-01-20 00:00:00

abstract：:While significant advances have been made in the prevention and treatment of malaria in recent years, these successes continue to fall short of the World Health Organization (WHO) goals for malaria control and elimination. For elimination strategies to be effective, limited disease transmission, achieved through rapid...

journal_title：Malaria journal

authors： Makanga M

更新日期：2014-07-28 00:00:00