A review of the effects of artemether-lumefantrine on gametocyte carriage and disease transmission.

abstract：BACKGROUND:Private sector availability and use of malaria rapid diagnostic tests (RDTs) lags behind the public sector in Kenya. Increasing channels through which quality malaria diagnostic services are available can improve access to testing and help meet the target of universal diagnostic testing. Registered pharmacie...

journal_title：Malaria journal

authors： Poyer S,Musuva A,Njoki N,Okara R,Cutherell A,Sievers D,Lussiana C,Memusi D,Kiptui R,Ejersa W,Dolan S,Charman N

更新日期：2018-03-13 00:00:00

abstract：BACKGROUND:Global malaria control strategies highlight the need to increase early uptake of effective antimalarials for childhood fevers in endemic settings, based on a presumptive diagnosis of malaria in this age group. Many control programmes identify private medicine sellers as important targets to promote effective...

journal_title：Malaria journal

authors： Abuya TO,Mutemi W,Karisa B,Ochola SA,Fegan G,Marsh V

更新日期：2007-05-10 00:00:00

abstract：BACKGROUND:The circumsporozoite protein (CS protein) on the malaria parasites in mosquitoes plays an important role in sporogony in mosquitoes. The RTS,S/AS01 malaria vaccine candidate, which has shown significant efficacy against clinical malaria in a large Phase 3 trial, targets the Plasmodium falciparum CS protein, ...

journal_title：Malaria journal

authors： Miura K,Jongert E,Deng B,Zhou L,Lusingu JP,Drakeley CJ,Fay MP,Long CA,Vekemans J

更新日期：2014-07-09 00:00:00

abstract：BACKGROUND:The ACT recommended by WHO is very effective and well-tolerated. However, these combinations need to be administered for three days, which may limit adherence to treatment.The combination of dihydroartemisinin-piperaquine phosphate-trimethoprim (Artecom®, Odypharm Ltd), which involves treatment over two days...

journal_title：Malaria journal

authors： Menan H,Faye O,Same-Ekobo A,Oga AS,Faye B,Kiki Barro CP,Kuete T,N'diaye JL,Vicky AM,Tine R,Yavo W,Kane D,Kassi KF,Kone M

更新日期：2011-07-08 00:00:00

abstract：BACKGROUND:Rhoptries are the large, paired, secretory organelles located at the apical tip of the malaria merozoite that are considered important for parasite invasion processes. Plasmodium vivax rhoptry proteins have been shown to induce humoral immunity during natural infections. Therefore, these proteins may be pote...

journal_title：Malaria journal

authors： Kochayoo P,Changrob S,Wangriatisak K,Lee SK,Chootong P,Han ET

更新日期：2019-11-29 00:00:00

abstract：BACKGROUND:The effectiveness of vector control on malaria transmission by long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) depends on the vectors entering houses to blood feed and rest when people are inside houses. In the Solomon Islands, significant reductions in malaria have been achieved in...

journal_title：Malaria journal

authors： Russell TL,Beebe NW,Bugoro H,Apairamo A,Chow WK,Cooper RD,Collins FH,Lobo NF,Burkot TR

更新日期：2016-03-10 00:00:00

abstract：BACKGROUND:Malaria is a major public health issue in Burundi in terms of both morbidity and mortality, with around 2.5 million clinical cases and more than 15,000 deaths each year. It is still the single main cause of mortality in pregnant women and children below five years of age. Because of the severe health and eco...

journal_title：Malaria journal

authors： Nkurunziza H,Gebhardt A,Pilz J

更新日期：2011-08-11 00:00:00

abstract：BACKGROUND:The effectiveness of malaria control programmes through implementation of vector control activities is challenged by the emergence of insecticide resistance. In the South-Eastern region of Côte d'Ivoire, where palm oil plantations remain the predominant agricultural crop, the susceptibility of wild Anopheles...

journal_title：Malaria journal

authors： Sadia-Kacou CMA,Alou LPA,Edi AVC,Yobo CM,Adja MA,Ouattara AF,Malone D,Koffi AA,Tano Y,Koudou BG

更新日期：2017-04-20 00:00:00

abstract：BACKGROUND:Modelling risk of malaria in longitudinal studies is common, because individuals are at risk for repeated infections over time. Malaria infections result in acquired immunity to clinical malaria disease. Prospective cohorts are an ideal design to relate the historical exposure to infection and development of...

journal_title：Malaria journal

authors： Stanley CC,Kazembe LN,Mukaka M,Otwombe KN,Buchwald AG,Hudgens MG,Mathanga DP,Laufer MK,Chirwa TF

更新日期：2019-07-29 00:00:00

abstract：:This meeting report presents the key findings and discussion points of a 1-day meeting entitled 'Fake anti-malarials: start with the facts' held on 28th May 2015, in Geneva, Switzerland, to disseminate the findings of the artemisinin combination therapy consortium's drug quality programme. The teams purchased over 10,...

journal_title：Malaria journal

authors： Kaur H,Clarke S,Lalani M,Phanouvong S,Guérin P,McLoughlin A,Wilson BK,Deats M,Plançon A,Hopkins H,Miranda D,Schellenberg D

更新日期：2016-02-13 00:00:00

abstract：BACKGROUND:As South Africa strives to achieve malaria elimination by 2018 (zero local cases) the country needs to strengthen its disease surveillance system by reducing the timeliness from case diagnosis to notification of key stakeholders in the malaria programme. This study evaluated the feasibility of a 24-h mobile ...

journal_title：Malaria journal

authors： Baloyi RE,Shandukani MB,Graffy R,Misiani E,Mayet N,Mabunda E,Mabuza A,Qwabe B,Ngwenyama B,Reddy C,Moonasar D

更新日期：2018-08-23 00:00:00

abstract：BACKGROUND:Malaria is seasonal and this may influence the number of children being treated as outpatients in hospitals. The objective of this study was to investigate the degree of seasonality in malaria in lakeshore and highland areas of Zomba district Malawi, and influence of climatic factors on incidence of malaria....

journal_title：Malaria journal

authors： Hajison PL,Mwakikunga BW,Mathanga DP,Feresu SA

更新日期：2017-07-03 00:00:00

abstract：BACKGROUND:This study was conducted to evaluate whether a selection of South African ethnomedicinal plants included in this study displayed insecticidal properties when screened against adult stages of the mosquito. METHODS:381 crude extracts of 80 plant taxa in 42 families were sprayed onto ceramic tiles and screened...

journal_title：Malaria journal

authors： Maharaj R,Maharaj V,Crouch NR,Bhagwandin N,Folb PI,Pillay P,Gayaram R

更新日期：2011-08-11 00:00:00

abstract：BACKGROUND:The WHO has reported that RDT and microscopy-confirmed malaria cases have declined in recent years. However, it is still unclear if this reflects a real decrease in incidence in Bangladesh, as particularly the hilly and forested areas of the Chittagong Hill Tract (CHT) Districts report more than 80% of all c...

journal_title：Malaria journal

authors： Starzengruber P,Fuehrer HP,Ley B,Thriemer K,Swoboda P,Habler VE,Jung M,Graninger W,Khan WA,Haque R,Noedl H

更新日期：2014-01-09 00:00:00

abstract：BACKGROUND:While sub-microscopic malarial infections are frequent and potentially deleterious during pregnancy, routine molecular detection is still not feasible. This study aimed to assess the performance of a Histidine Rich Protein 2 (HRP2)-based ultrasensitive rapid diagnostic test (uRDT, Alere Malaria Ag Pf) for th...

journal_title：Malaria journal

authors： Briand V,Cottrell G,Tuike Ndam N,Martiáñez-Vendrell X,Vianou B,Mama A,Kouwaye B,Houzé S,Bailly J,Gbaguidi E,Sossou D,Massougbodji A,Accrombessi M,Mayor A,Ding XC,Fievet N

更新日期：2020-05-24 00:00:00

abstract：BACKGROUND:Within the context of increasing antimalarial costs and or decreasing malaria transmission, the importance of limiting antimalarial treatment to only those confirmed as having malaria parasites becomes paramount. This motivates for this assessment of the cost-effectiveness of routine use of rapid diagnostic ...

journal_title：Malaria journal

authors： Zikusooka CM,McIntyre D,Barnes KI

更新日期：2008-09-15 00:00:00

abstract：BACKGROUND:In the Tanga District of coastal Tanzania, malaria is one of the primary causes of mortality for children under the age of five. While some children are treated with malaria medications in biomedical facilities, as the World Health Organization recommends, others receive home-care or treatment from tradition...

journal_title：Malaria journal

authors： Foster D,Vilendrer S

更新日期：2009-10-27 00:00:00

abstract：BACKGROUND:The standard in vitro protocol currently in use for drug testing against Plasmodium falciparum, based on the incorporation of the purine [3H]-hypoxanthine, has two serious drawbacks. Firstly it is unsuitable for the testing of drugs that directly or indirectly impact on purine salvage or metabolism. Secondly...

journal_title：Malaria journal

authors： Quashie NB,de Koning HP,Ranford-Cartwright LC

更新日期：2006-10-31 00:00:00

abstract：BACKGROUND:Fixed-dose combination antimalarial drugs have played an increasingly important role in the treatment and chemoprophylaxis of falciparum malaria since the worldwide failure of monotherapy with chloroquine. Atovaquone-proguanil is one such combination drug used both for prophylaxis in travellers, and for trea...

journal_title：Malaria journal

authors： Sutherland CJ,Laundy M,Price N,Burke M,Fivelman QL,Pasvol G,Klein JL,Chiodini PL

更新日期：2008-11-20 00:00:00

abstract：BACKGROUND:Artemisinin-based combination therapy (ACT) has been recommended for the treatment of falciparum malaria by the World Health Organization. Though India has already switched to ACT for treating falciparum malaria, there is need to have multiple options of alternative forms of ACT. A randomized trial was condu...

journal_title：Malaria journal

authors： Anvikar AR,Sharma B,Shahi BH,Tyagi PK,Bose TK,Sharma SK,Srivastava P,Srivastava B,Kiechel JR,Dash AP,Valecha N

更新日期：2012-03-30 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the profile of antibodies against several antigens of Plasmodium vivax and Plasmodium falciparum in Mandalay, Myanmar. METHODS:Malaria parasites were identified by microscopic examination. To test the antibodies against P. vivax and P. falciparum in sera, an indirect...

journal_title：Malaria journal

authors： Kim TS,Kim HH,Kim JY,Kong Y,Na BK,Lin K,Moon SU,Kim YJ,Kwon MH,Sohn Y,Kim H,Lee HW

更新日期：2011-08-06 00:00:00

abstract：BACKGROUND:Malaria remains a major human health problem, with no licensed vaccine currently available. Malaria infections initiate when infectious Plasmodium sporozoites are transmitted by Anopheline mosquitoes during their blood meal. Investigations of the malaria sporozoite are, therefore, of clear medical importance...

journal_title：Malaria journal

authors： Kennedy M,Fishbaugher ME,Vaughan AM,Patrapuvich R,Boonhok R,Yimamnuaychok N,Rezakhani N,Metzger P,Ponpuak M,Sattabongkot J,Kappe SH,Hume JC,Lindner SE

更新日期：2012-12-17 00:00:00

abstract：BACKGROUND:The diversity of genotyping markers of Plasmodium falciparum depends on transmission intensity. It has been reported that the diversity of the merozoite surface protein 2 (msp2) is greater in areas of high compared to low endemicity, however, results for msp1 were inconsistent. These previous reports relied ...

journal_title：Malaria journal

authors： Schoepflin S,Valsangiacomo F,Lin E,Kiniboro B,Mueller I,Felger I

更新日期：2009-10-30 00:00:00

abstract：BACKGROUND:New World vultures (Cathartiformes: Cathartidae) are obligate scavengers comprised of seven species in five genera throughout the Americas. Of these, turkey vultures (Cathartes aura) and black vultures (Coragyps atratus) are the most widespread and, although ecologically similar, have evolved differences in ...

journal_title：Malaria journal

authors： Yabsley MJ,Vanstreels RET,Martinsen ES,Wickson AG,Holland AE,Hernandez SM,Thompson AT,Perkins SL,West CJ,Bryan AL,Cleveland CA,Jolly E,Brown JD,McRuer D,Behmke S,Beasley JC

更新日期：2018-01-08 00:00:00

abstract：BACKGROUND:Long-lasting insecticidal nets (LLINs) are the primary malaria prevention and control intervention in many parts of sub-Saharan Africa. While LLINs are expected to last at least 3 years under normal use conditions, they can lose effectiveness because they fall out of use, are discarded, repurposed, physicall...

journal_title：Malaria journal

authors： Briet O,Koenker H,Norris L,Wiegand R,Vanden Eng J,Thackeray A,Williamson J,Gimnig JE,Fortes F,Akogbeto M,Yadouleton AW,Ombok M,Bayoh MN,Mzilahowa T,Abílio AP,Mabunda S,Cuamba N,Diouf E,Konaté L,Hamainza B,Katebe-S

更新日期：2020-08-28 00:00:00

abstract：BACKGROUND:A malaria vaccine based on Plasmodium falciparum apical membrane antigen 1 (AMA1) elicited strain specific efficacy in Malian children that waned in the second season after vaccination despite sustained AMA1 antibody titers. With the goal of identifying a humoral correlate of vaccine-induced protection, pre-...

journal_title：Malaria journal

authors： Berry AA,Gottlieb ER,Kouriba B,Diarra I,Thera MA,Dutta S,Coulibaly D,Ouattara A,Niangaly A,Kone AK,Traore K,Tolo Y,Mishcherkin V,Soisson L,Diggs CL,Blackwelder WC,Laurens MB,Sztein MB,Doumbo OK,Plowe CV,Lyke KE

更新日期：2019-01-18 00:00:00

abstract：BACKGROUND:Parasites from the genus Plasmodium, the aetiological agent of malaria in humans, can also infect non-human primates (NHP), increasing the potential risk of zoonotic transmission with its associated global public health concerns. In Colombia, there are no recent studies on Plasmodium spp. infecting free-rang...

journal_title：Malaria journal

authors： Rondón S,León C,Link A,González C

更新日期：2019-08-19 00:00:00

abstract：BACKGROUND:Increases in the coverage of long-lasting insecticidal nets (LLINs) have significantly reduced the abundance of Anopheles gambiae sensu stricto in several African settings, leaving its more zoophagic sibling species Anopheles arabiensis as the primary vector. This study investigated the impact of livestock o...

journal_title：Malaria journal

authors： Mayagaya VS,Nkwengulila G,Lyimo IN,Kihonda J,Mtambala H,Ngonyani H,Russell TL,Ferguson HM

更新日期：2015-01-21 00:00:00

abstract：BACKGROUND:Malaria and schistosomiasis are endemic and co-exist in the same geographic areas, even co-infecting the same host. Previous studies have reported that concomitant infection with Schistosoma japonicum could offer protection against experimental cerebral malaria (ECM) in mice. This study was performed to eval...

journal_title：Malaria journal

authors： Wang ML,Feng YH,Pang W,Qi ZM,Zhang Y,Guo YJ,Luo EJ,Cao YM

更新日期：2014-03-26 00:00:00

abstract：BACKGROUND:A successful malaria control programme began in 2004 on Bioko Island, Equatorial Guinea. From 2007, the same multiple malaria interventions, though reduced in scope for funding reasons, were introduced to the four mainland provinces of Equatorial Guinea (the continental region) aiming to recreate Bioko's suc...

journal_title：Malaria journal

authors： Rehman AM,Mann AG,Schwabe C,Reddy MR,Roncon Gomes I,Slotman MA,Yellott L,Matias A,Caccone A,Nseng Nchama G,Kleinschmidt I

更新日期：2013-05-07 00:00:00