Parasitaemia data and molecular characterization of Haemoproteus catharti from New World vultures (Cathartidae) reveals a novel clade of Haemosporida.

abstract：BACKGROUND:The current status of insecticide resistance and the underlying resistance mechanisms were studied in the major vector of malaria, Anopheles culicifacies, and the secondary vector, Anopheles subpictus in five districts (Anuradhapura, Kurunegala, Moneragala, Puttalam and Trincomalee) of Sri Lanka. Eight other...

journal_title：Malaria journal

authors： Perera MD,Hemingway J,Karunaratne SP

更新日期：2008-08-28 00:00:00

abstract：BACKGROUND:The receptors for adhesion of Plasmodium falciparum-infected red blood cells (RBC) in the placenta have been identified as chondroitin-4-sulphate (C4S) proteoglycans, and the more sulphate-rich chondroitin oligosaccharides have been reported to inhibit adhesion. Since the anti-malarial drug chloroquine accum...

journal_title：Malaria journal

authors： Bhattacharyya S,Solakyildirim K,Zhang Z,Linhardt RJ,Tobacman JK

更新日期：2009-12-17 00:00:00

abstract：BACKGROUND:Antibody immunity is thought to be essential to prevent severe Plasmodium falciparum infection, but the exact correlates of protection are unknown. Over time, children in endemic areas acquire non-sterile immunity to malaria that correlates with development of antibodies to merozoite invasion proteins and pa...

journal_title：Malaria journal

authors： Kessler A,Campo JJ,Harawa V,Mandala WL,Rogerson SJ,Mowrey WB,Seydel KB,Kim K

更新日期：2018-04-25 00:00:00

abstract：BACKGROUND:Zoonotic infections with epidemic potential, as non-human primate malaria and yellow fever (YF), can overlap geographically. Optimizing a small blood sample for diagnosis and surveillance is of great importance. Blood are routinely collected for YF diagnosis and blood clots usually discarded after serum obte...

journal_title：Malaria journal

authors： de Abreu FVS,Gomes LR,Mello ARL,Bianco-Júnior C,de Pina-Costa A,Dos Santos E,Teixeira DS,Brasil P,Daniel-Ribeiro CT,Lourenço-de-Oliveira R,de Fátima Ferreira-da-Cruz M

更新日期：2018-09-24 00:00:00

abstract：BACKGROUND:Prompt, quality assured laboratory diagnosis is key to effective malaria case management and control, especially since the introduction of the more expensive artemisinin combination therapy (ACT). The malaria programme and its non-government partners, on the basis of WHO recommended Lot Quality Assurance met...

journal_title：Malaria journal

authors： Khan MA,Walley JD,Munir MA,Khan MA,Khokar NG,Tahir Z,Nazir A,Shams N

更新日期：2011-02-17 00:00:00

abstract：BACKGROUND:Despite some problems related to accuracy and applicability, malaria rapid diagnostic tests (RDTs), are currently considered the best option in areas with limited laboratory services for improving case management and reducing over-treatment. However, their performance must be established taking into the acco...

journal_title：Malaria journal

authors： Muhindo HM,Ilombe G,Meya R,Mitashi PM,Kutekemeni A,Gasigwa D,Lutumba P,Van Geertruyden JP

更新日期：2012-07-06 00:00:00

abstract：BACKGROUND:Malaria treatment policy recommends regular monitoring of drug utilization to generate information for ensuring effective use of anti-malarial drugs in Nigeria. This information is currently limited in the retail sector which constitutes a major source of malaria treatment in Nigeria, but are characterized b...

journal_title：Malaria journal

authors： Ezenduka CC,Ogbonna BO,Ekwunife OI,Okonta MJ,Esimone CO

更新日期：2014-06-24 00:00:00

abstract：BACKGROUND:Information is needed on the expected durability of insecticidal nets under operational conditions. The persistence of insecticidal efficacy is important to estimate the median serviceable life of nets under field conditions and to plan for net replacement. METHODS:Deltamethrin residue levels were evaluated...

journal_title：Malaria journal

authors： Anshebo GY,Graves PM,Smith SC,Wills AB,Damte M,Endeshaw T,Shargie EB,Gebre T,Mosher AW,Patterson AE,Emerson PM

更新日期：2014-03-06 00:00:00

abstract：BACKGROUND:Malaria is one of the most severe public health issues that result in massive morbidity and mortality in most countries of the sub-Saharan Africa (SSA). This study aimed to determine the scope of household, accessibility to malaria care and factors associated with household malaria in the Democratic Republic...

journal_title：Malaria journal

authors： Ngatu NR,Kanbara S,Renzaho A,Wumba R,Mbelambela EP,Muchanga SMJ,Muzembo BA,Leon-Kabamba N,Nattadech C,Suzuki T,Oscar-Luboya N,Wada K,Ikeda M,Nojima S,Sugishita T,Ikeda S

更新日期：2019-02-26 00:00:00

abstract：BACKGROUND:Complement (C) can be activated during malaria, C components consumed and inflammatory mediators produced. This has potential to impair host innate defence. METHODS:In a case-control study, C activation was assessed by measuring serum haemolytic activity (CH50), functional activity of each pathway and level...

journal_title：Malaria journal

authors： Nyakoe NK,Taylor RP,Makumi JN,Waitumbi JN

更新日期：2009-01-09 00:00:00

abstract：BACKGROUND:Malaria can be transmitted by blood transfusion through donations collected from asymptomatic or parasitic donors. The parasites are released into the bloodstream during its life cycle and will therefore be present in donated blood by infected individuals. All cases of transfusion-transmitted malaria (TTM) n...

journal_title：Malaria journal

authors： Batista-Dos-Santos SA,Freitas DRC,Raiol M,Cabral GF,Feio AC,Póvoa MM,Cunha MG,Ribeiro-Dos-Santos Â

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The accuracy of the World Health Organization method of estimating malaria parasite density from thick blood smears by assuming a white blood cell (WBC) count of 8,000/μL has been questioned in several studies. Since epidemiological investigations, anti-malarial efficacy trials and routine laboratory reporti...

journal_title：Malaria journal

authors： Laman M,Moore BR,Benjamin J,Padapu N,Tarongka N,Siba P,Betuela I,Mueller I,Robinson LJ,Davis TM

更新日期：2014-04-16 00:00:00

abstract：BACKGROUND:Prompt and correct diagnosis of malaria is crucial for accurate epidemiological assessment and better case management, and while the gold standard of light microscopy is often available, it requires both expertise and time. Portable fluorescent microscopy using the CyScope offers a potentially quicker, easie...

journal_title：Malaria journal

authors： Sousa-Figueiredo JC,Oguttu D,Adriko M,Besigye F,Nankasi A,Arinaitwe M,Namukuta A,Betson M,Kabatereine NB,Stothard JR

更新日期：2010-08-27 00:00:00

abstract：:Recent WHO guidelines recommend a universal "test and treat" strategy for malaria, mainly by use of rapid diagnostic test (RDT) in all areas. The evidence for this approach is questioned here as there is a risk of over-reliance on parasitological diagnosis in high transmission situations, which still exist. In such ar...

journal_title：Malaria journal

authors： Graz B,Willcox M,Szeless T,Rougemont A

更新日期：2011-05-20 00:00:00

abstract：:Most malaria-endemic countries have struggled in the past decade to establish effective national-scale continuous distribution mechanisms for long-lasting insecticidal nets (LLINs). Since the implementation of the Tanzania National Voucher Scheme in 2004 and mass-distribution campaigns in 2009-2011 and 2015-2016, Tanz...

journal_title：Malaria journal

authors： Yukich J,Stuck L,Scates S,Wisniewski J,Chacky F,Festo C,Kabulika G,Dimoso K,Mandike R,Greer G,Serbantez N,Elisaria E,Nyoni W,Dadi D,Akim I,Lengeler C,Brown N,Koenker H

更新日期：2020-04-17 00:00:00

abstract：BACKGROUND:Rapid diagnostic tests (RDTs) have become the most common diagnostic tool for detection of Plasmodium falciparum malaria, in particular in remote areas. RDT blood spots provide a source of parasite DNA for molecular analysis. In this study, the utility of RDTs for molecular analysis and the performance of di...

journal_title：Malaria journal

authors： Srisutham S,Suwannasin K,Mathema VB,Sriprawat K,Smithuis FM,Nosten F,White NJ,Dondorp AM,Imwong M

更新日期：2020-05-27 00:00:00

abstract：BACKGROUND:Most malaria rapid diagnostic tests (RDTs) detect Plasmodium falciparum and an antigen common to the four species. Plasmodium vivax-specific RDTs target P. vivax-specific parasite lactate dehydrogenase (Pv-pLDH). Previous observations of false positive Pv-pLDH test lines in P. falciparum samples incited to t...

journal_title：Malaria journal

authors： Maltha J,Gillet P,Cnops L,van den Ende J,van Esbroeck M,Jacobs J

更新日期：2010-07-10 00:00:00

abstract：BACKGROUND:Malaria is a widespread infectious disease that threatens a large proportion of the population in tropical and subtropical areas. Given the emerging resistance against the current standard anti-malaria chemotherapeutics, the development of alternative drugs is urgently needed. New anti-malarials representing...

journal_title：Malaria journal

authors： Weidner T,Lucantoni L,Nasereddin A,Preu L,Jones PG,Dzikowski R,Avery VM,Kunick C

更新日期：2017-05-15 00:00:00

abstract：BACKGROUND:Control of the major African malaria vector species continues to rely extensively on the application of residual insecticides through indoor house spraying or bed net impregnation. Insecticide resistance is undermining the sustainability of these control strategies. Alternatives to the currently available co...

journal_title：Malaria journal

authors： Kikankie CK,Brooke BD,Knols BG,Koekemoer LL,Farenhorst M,Hunt RH,Thomas MB,Coetzee M

更新日期：2010-03-08 00:00:00

abstract：BACKGROUND:A malaria vaccine based on Plasmodium falciparum apical membrane antigen 1 (AMA1) elicited strain specific efficacy in Malian children that waned in the second season after vaccination despite sustained AMA1 antibody titers. With the goal of identifying a humoral correlate of vaccine-induced protection, pre-...

journal_title：Malaria journal

authors： Berry AA,Gottlieb ER,Kouriba B,Diarra I,Thera MA,Dutta S,Coulibaly D,Ouattara A,Niangaly A,Kone AK,Traore K,Tolo Y,Mishcherkin V,Soisson L,Diggs CL,Blackwelder WC,Laurens MB,Sztein MB,Doumbo OK,Plowe CV,Lyke KE

更新日期：2019-01-18 00:00:00

abstract：BACKGROUND:Rapid diagnostic tests (RDTs) for histidine rich protein 2 (HRP2) are often used to determine whether persons with fever should be treated with anti-malarials. However, Plasmodium falciparum parasites with a deletion of the hrp2 gene yield false-negative RDTs and there are concerns the sensitivity of HRP2-ba...

journal_title：Malaria journal

authors： Kozycki CT,Umulisa N,Rulisa S,Mwikarago EI,Musabyimana JP,Habimana JP,Karema C,Krogstad DJ

更新日期：2017-03-20 00:00:00

abstract：BACKGROUND:The emergence of Plasmodium falciparum resistance to artemisinins threatens to undermine the effectiveness of artemisinin-based combination anti-malarial therapy. Developing suitable drugs to replace artemisinins requires the identification of new compounds that display rapid parasite killing kinetics. Howev...

journal_title：Malaria journal

authors： Linares M,Viera S,Crespo B,Franco V,Gómez-Lorenzo MG,Jiménez-Díaz MB,Angulo-Barturen Í,Sanz LM,Gamo FJ

更新日期：2015-11-05 00:00:00

abstract：BACKGROUND:Malaria is seasonal and this may influence the number of children being treated as outpatients in hospitals. The objective of this study was to investigate the degree of seasonality in malaria in lakeshore and highland areas of Zomba district Malawi, and influence of climatic factors on incidence of malaria....

journal_title：Malaria journal

authors： Hajison PL,Mwakikunga BW,Mathanga DP,Feresu SA

更新日期：2017-07-03 00:00:00

abstract：BACKGROUND:Donor financing for malaria has declined since 2010 and this trend is projected to continue for the foreseeable future. These reductions have a significant impact on lower burden countries actively pursuing elimination, which are usually a lesser priority for donors. While domestic spending on malaria has be...

journal_title：Malaria journal

authors： Shretta R,Zelman B,Birger ML,Haakenstad A,Singh L,Liu Y,Dieleman J

更新日期：2017-07-14 00:00:00

abstract：:The Global Technical Strategy 2016-2030 of the World Health Organization (WHO) has the ambitious goal of malaria being eliminated from at least 35 countries by 2030. However, in areas with once-stable malaria transmission, the reservoir of human infection may be intermittently symptomatic or fully silent yet still lea...

journal_title：Malaria journal

authors： Eisele TP

更新日期：2019-08-22 00:00:00

abstract：BACKGROUND:The diversity and abundance of Anopheles larvae has significant influence on the resulting adult mosquito population and hence the dynamics of malaria transmission. Studies were conducted to examine larval habitat dynamics and ecological factors affecting survivorship of aquatic stages of malaria vectors in ...

journal_title：Malaria journal

authors： Mwangangi JM,Shililu J,Muturi EJ,Muriu S,Jacob B,Kabiru EW,Mbogo CM,Githure J,Novak RJ

更新日期：2010-08-09 00:00:00

abstract：BACKGROUND:Rosetting is associated with severe malaria and a primary cause of death in Plasmodium falciparum infections. Detailed understanding of this adhesive phenomenon may enable the development of new therapies interfering with rosette formation. For this, it is crucial to determine parameters such as rosetting an...

journal_title：Malaria journal

authors： Kudella PW,Moll K,Wahlgren M,Wixforth A,Westerhausen C

更新日期：2016-04-18 00:00:00

abstract：BACKGROUND:Heads of Government from Asia and the Pacific have committed to a malaria-free region by 2030. In 2015, the total number of confirmed cases reported to the World Health Organization by 22 Asia Pacific countries was 2,461,025. However, this was likely a gross underestimate due in part to incidence data not be...

journal_title：Malaria journal

authors： Mercado CE,Ekapirat N,Dondorp AM,Maude RJ

更新日期：2017-03-21 00:00:00

abstract：BACKGROUND:This study was conducted to evaluate whether a selection of South African ethnomedicinal plants included in this study displayed insecticidal properties when screened against adult stages of the mosquito. METHODS:381 crude extracts of 80 plant taxa in 42 families were sprayed onto ceramic tiles and screened...

journal_title：Malaria journal

authors： Maharaj R,Maharaj V,Crouch NR,Bhagwandin N,Folb PI,Pillay P,Gayaram R

更新日期：2011-08-11 00:00:00

abstract：BACKGROUND:Internally displaced persons (IDP) represent vulnerable populations whose public health conditions merit special attention. In the China-Myanmar border area, human movement and resettlements of IDP can influence malaria transmission. Comparison of disease incidence and vector densities between IDP camps and ...

journal_title：Malaria journal

authors： Zhou G,Lo E,Zhong D,Wang X,Wang Y,Malla S,Lee MC,Yang Z,Cui L,Yan G

更新日期：2016-09-15 00:00:00