Reduced expression of microRNA-100 confers unfavorable prognosis in patients with bladder cancer.

abstract：OBJECTIVE:FNA is a simple, safe, cost-effective and accurate diagnostic tool for the initial screening of patients with thyroid nodules. The aims of this study were to determine the diagnostic utility of FNAC performed in our institution, assess the cytomorphologic features that contribute to diagnostic errors and prop...

journal_title：Diagnostic pathology

authors： Zhu Y,Song Y,Xu G,Fan Z,Ren W

更新日期：2020-01-03 00:00:00

abstract：UNLABELLED:Atypical teratoid/rhabdoid tumors are rare and highly malignant central nervous system tumors. They have no specific radiological features and often present several histological components that make a problem in differential diagnosis with medulloblastoma and primitive neuroectodermal tumors. We present the ...

journal_title：Diagnostic pathology

authors： Mahdi Y,Kharmoum J,Alouan A,Elouarradi H,Elkhiyat I,Maher M,Benchrif MZ,Kili A,Daoudi R,Cherradi N

更新日期：2015-05-02 00:00:00

abstract：BACKGROUND:Evaluation of core needle biopsies (CNB) is a standard procedure for the diagnosis of breast cancer. However, tissue processing and image preparation is a time- consuming procedure and instant on-site availability of high-quality images could substantially improve the efficacy of the diagnostic procedure. Co...

journal_title：Diagnostic pathology

authors： Elfgen C,Papassotiropoulos B,Varga Z,Moskovszky L,Nap M,Güth U,Baege A,Amann E,Chiesa F,Tausch C

更新日期：2019-06-15 00:00:00

abstract：BACKGROUND:Ki67 is currently the proliferation biomarker of choice, with both prognostic and predictive value in breast cancer. A lack of consensus regarding Ki67 use in pre-analytical, analytical and post-analytical practice may hinder its formal acceptance in the clinical setting. METHODS:One hundred breast cancer s...

journal_title：Diagnostic pathology

authors： Romero Q,Bendahl PO,Fernö M,Grabau D,Borgquist S

更新日期：2014-06-16 00:00:00

abstract：BACKGROUND:Isolated hypothalamic-pituitary Langerhans cell histiocytosis (HPLCH) is very rare. We investigated the clinicopathological characteristics, endocrine function changes, BRAFV600E mutations and treatments of isolated HPLCH. METHODS:We identified seven patients with isolated HPLCH by reviewing the clinical an...

journal_title：Diagnostic pathology

authors： Huo Z,Lu T,Liang Z,Ping F,Shen J,Lu J,Ma W,Zhao D,Zhong D

更新日期：2016-10-19 00:00:00

abstract：BACKGROUND:Nuclear protein in testis (NUT) midline carcinomas (NMC) are rare, highly aggressive epithelial neoplasms, characterised by protein expression of NUT-fusion proteins which reflects the genetic translocation between chromosome 15 and 19. NMC occurs mainly in midline structures, but there are reports regarding...

journal_title：Diagnostic pathology

authors： Lund-Iversen M,Grøholt KK,Helland Å,Borgen E,Brustugun OT

更新日期：2015-09-05 00:00:00

abstract：UNLABELLED:Imaging appearance of cyst-like changes is most frequently described in primary neuroendocrine lesions, especially pancreatic NETs.The imaging finding of a pseudocystic lesion of the liver puts in differential diagnosis many pathologies such as infectious diseases, simple biliary cysts up to biliary cystaden...

journal_title：Diagnostic pathology

authors： Fiori S,Del Gobbo A,Gaudioso G,Caccamo L,Massironi S,Cavalcoli F,Bosari S,Ferrero S

更新日期：2013-09-13 00:00:00

abstract：BACKGROUND:ABCG2 is an ABC transporter. It has been demonstrated that endogenous ABCG2 expression in certain cancers is a possible reflection of the differentiated phenotype of the cell of origin and likely contributes to intrinsic drug resistance. But little is known about the contribution of ABCG2 to the drug resista...

journal_title：Diagnostic pathology

authors： Xiang L,Su P,Xia S,Liu Z,Wang Y,Gao P,Zhou G

更新日期：2011-09-27 00:00:00

abstract：:Meningioma, craniopharyngeoma and glioma are mainly intracranial lesions. Nevertheless, in rare cases these entities may occur solely as extracranial lesions that may present as intranasal/sinusoidal masses, with headaches and nasal obstruction. We present three cases of common intracranial tumors, with purely extracr...

journal_title：Diagnostic pathology

authors： Arndt S,Wiech T,Mader I,Aschendorff A,Maier W

更新日期：2008-04-16 00:00:00

abstract：BACKGROUND:The tumor transformation mechanism of a plasmacytoid urothelial carcinoma remains unexplained. We describe the case of a plasmacytoid urothelial carcinoma of the renal pelvis in which the expression of zinc finger E-box-binding homeobox 1 (ZEB1), a key nuclear transcription factor in an epithelial-mesenchyma...

journal_title：Diagnostic pathology

authors： Takada-Owada A,Nozawa Y,Onozaki M,Noda S,Jamiyan T,Tokura Y,Nakazato Y,Kamai T,Ishida K

更新日期：2020-10-08 00:00:00

abstract：OBJECTIVES:Non-Hodgkin's lymphoma (NHL) primarily derived from the base of the tongue, is rare. Human papillomavirus (HPV) and Epstein-Barr virus (EBV) are important aetiological risk factors for tumours of the head and neck. This study describes the clinicopathological features of NHL in the tongue base and the status...

journal_title：Diagnostic pathology

authors： Ren X,Cheng Y,Wu S,Zeng X,Shi X,Ling Q,Li Z,Liang Z,Wang B

更新日期：2020-04-01 00:00:00

abstract：UNLABELLED:Metastatic renal cell carcinoma in the gallbladder is extremely rare, with reported frequencies of less than 0.6% in large autopsy reviews. Only 40 cases were reported in the literature. We report a first case of gallbladder polypoid tumor revealing metastatic clear cell renal cell carcinoma, which demonstra...

journal_title：Diagnostic pathology

authors： Ghaouti M,Znati K,Jahid A,Zouaidia F,Bernoussi Z,El Fakir Y,Mahassini N

更新日期：2013-01-10 00:00:00

abstract：:Cutaneous apocrine carcinoma (AC) is a rare adnexal neoplasm that histologically can mimic breast carcinoma metastatic to the skin or apocrine carcinoma arising in ectopic breast tissue. As extremely rare condition, neuroendocrine differentiation may be observed in AC although its etiology and pathogenesis is still un...

journal_title：Diagnostic pathology

authors： Li Y,Chen LL,Li B,Tian XY,Li Z

更新日期：2015-06-10 00:00:00

abstract：BACKGROUND:Adult granulosa cell tumors of the ovary (GCTs) are sex cord stromal tumors of unpredictable behaviour. Up to now, the prediction of the relapsing/malignant potential remains difficult. CD56 (NCAM) in GCTs was previously described in only two studies. However, the expression of its isoforms was not examined....

journal_title：Diagnostic pathology

authors： Völker HU,Engert S,Cramer A,Schmidt M,Kämmerer U,Müller-Hermelink HK,Gattenlöhner S

更新日期：2008-07-09 00:00:00

abstract：BACKGROUND:The histopathological subtype, nuclear grade and presence or absence of comedonecrosis are established as critical elements in the reporting of ductal carcinoma in situ (DCIS) of the breast. The aims of this study were to determine the frequencies of morphological subtypes of DCIS, nuclear grade and comedone...

journal_title：Diagnostic pathology

authors： Perez AA,Balabram D,Salles Mde A,Gobbi H

更新日期：2014-12-03 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) remains a major worldwide cause of cancer-related morbidity and mortality largely due to the insidious onset of the disease. The current clinical procedures utilized for disease diagnosis are invasive, unpleasant, and inconvenient. Hence, the need for simple blood tests that could be ...

journal_title：Diagnostic pathology

authors： Fan NJ,Kang R,Ge XY,Li M,Liu Y,Chen HM,Gao CF

更新日期：2014-03-12 00:00:00

abstract：UNLABELLED:Perivascular epithelioid cell tumors (PEComas) encompass a group of rare mesenchymal neoplasms, which typically have a perivascular location with dual melanocytic and muscular differentiation. They are found in a variety of localizations, though lesions in the liver are exceedingly rare. Because of their rar...

journal_title：Diagnostic pathology

authors： Ameurtesse H,Chbani L,Bennani A,Toughrai I,Beggui N,Kamaoui I,Elfatemi H,Harmouch T,Amarti A

更新日期：2014-07-17 00:00:00

abstract：BACKGROUND:Hyalinizing clear cell carcinoma (HCCC) is a rare low-grade tumour of salivary glands that was first described as a distinct entity in 1994 by Milchgrub et al. EWSR1-ATF1 fusion was found to be specific for this tumour. The majority of the reported cases of HCCC arise from minor salivary glands within the or...

journal_title：Diagnostic pathology

authors： AlAli BM,Alyousef MJ,Kamel AS,Al Hamad MA,Al-Bar MH,Algowiez RM

更新日期：2017-09-25 00:00:00

abstract：BACKGROUND:Advancing knowledge in molecular pathogenesis of hepatocellular carcinoma (HCC) opens up new horizons in the diagnostic, prognostic and therapeutic perspectives. Assessing the expression of molecular targets prior to definitive treatment is gaining importance in clinical practice. In this study, we investiga...

journal_title：Diagnostic pathology

authors： Lo RC,Leung CO,Chok KS,Ng IO

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Mixed adeno-neuroendocrine carcinoma (MANEC) of the biliary tract is rare with only a few reported cases. Consequently, knowledge about their pathogenesis, histopathological characteristics and outcomes is sparce. CASE PRESENTATION:A 53-year old man presented with epigastric pain on a background of excessiv...

journal_title：Diagnostic pathology

authors： Zheng SL,Yip VS,Pedica F,Prachalias A,Quaglia A

更新日期：2015-11-20 00:00:00

abstract：BACKGROUND:Carbonic anhydrase IX is a member of α-carbonic anhydrases that is preferentially expressed in solid tumors. It enables bicarbonate transport across the plasma membrane, neutralizing intracellular pH and conferring to cancer cells a survival advantage in hypoxic/acidic microenvironments. Overexpression of ca...

journal_title：Diagnostic pathology

authors： Ambrosio MR,Di Serio C,Danza G,Rocca BJ,Ginori A,Prudovsky I,Marchionni N,Del Vecchio MT,Tarantini F

更新日期：2016-05-25 00:00:00

abstract：:Insights into the molecular underpinnings of primary central nervous system tumors have radically changed the approach to tumor diagnosis and classification. Diagnostic emphasis has shifted from the morphology of a tumor under the microscope to an integrated approach based on morphologic and molecular features, includ...

journal_title：Diagnostic pathology

authors： Wood MD,Halfpenny AM,Moore SR

更新日期：2019-04-09 00:00:00

abstract：BACKGROUND:The programmed death receptor 1 (PD-1) protein is a cell-surface receptor on certain lymphocytes that, with its ligand programmed death ligand 1 (PD-L1), helps to down-regulate immune responses. Many cancer types express PD-L1 and evade immune recognition via the PD-1/PD-L1 interaction. Precision therapies t...

journal_title：Diagnostic pathology

authors： Udall M,Rizzo M,Kenny J,Doherty J,Dahm S,Robbins P,Faulkner E

更新日期：2018-02-09 00:00:00

abstract：BACKGROUND:Kombucha, a fermented tea (KT) is claimed to possess many beneficial properties. The aim of this study was to evaluate clinical and histopathological alterations of Kombucha tea and Nitrofurazone on cutaneous full-thickness wounds healing in rat. METHODS:In present study 24 Wister -albino rats weighing 150-...

journal_title：Diagnostic pathology

authors： Barati F,Javanbakht J,Adib-Hashemi F,Hosseini E,Safaeie R,Rajabian M,Razmjoo M,Sedaghat R,Aghamohammad Hassan M

更新日期：2013-07-17 00:00:00

abstract：BACKGROUND:Intestinal metaplasia (IM) of the gastric mucosa is classified as complete (Type I) and incomplete IM (Type II and III) subtypes, which showed significantly different risk for developing to gastric adenocarcinoma (GAC). GCRG213, a variant of L1-endonuclease (L1-EN), first identified in our lab, was upregulat...

journal_title：Diagnostic pathology

authors： Duan X,Lian H,Li J,Wu B,Wang W,Wu T,Wang C,Dou Y,Zhou Z,Wang B,Xue L,Wang G

更新日期：2019-06-21 00:00:00

abstract：BACKGROUND:Special AT-rich sequence binding protein 1 (SATB1) is found acting as a "genome organizer" that functions as a landing platform to regulate tissue-specific gene ex-pression. In breast cancer cell lines it has been proven that SATB1 could upregulate the expression of the HER2. In this paper, the relevance of ...

journal_title：Diagnostic pathology

authors： Liu X,Zheng Y,Qiao C,Qv F,Wang J,Ding B,Sun Y,Wang Y

更新日期：2015-05-09 00:00:00

abstract：UNLABELLED:Giant cell angioblastoma (GCAB) is an extremely rare soft tissue tumor of early childhood and only five cases have been described to date. As such the clinical, pathological, and prognostic features are poorly defined. We prensent here a new case of GCAB in bone of a child aged 4-years old. The lesion was co...

journal_title：Diagnostic pathology

authors： Mao RJ,Jiang ZM,Zhang HZ,Zhu XZ,Zhang QL

更新日期：2012-08-29 00:00:00

abstract：BACKGROUND:Several studies reported the dysregulation of miR-541 in the progression of some human malignancies. Osteosarcoma (OS) is one of the most common primary malignant bone tumors. This study aimed to assess the expression and clinical significance of miR-541 in OS patients and explore the biological function of ...

journal_title：Diagnostic pathology

authors： Liu C,Yi X

更新日期：2020-07-24 00:00:00

abstract：:This research was conducted on ten glass slides selected from the histopathology evaluation chickens. Five slides of control's chickens healthy and five slides of chickens infected experimentally with chicken anemia virus (CAV slide) between one and twenty-one days post infection (PI), they were analyzed in magnificat...

journal_title：Diagnostic pathology

authors： García L,Bermudez V,Brett M,Peroza L,Landa J,Borregales F

更新日期：2008-07-15 00:00:00

abstract：BACKGROUND:High altitude pulmonary edema (HAPE) affects individuals and is characterized by alveolar flooding with protein-rich edema as a consequence of blood-gas barrier disruption. In this study, we hypothesized that aquaporin 5 (AQP5) which is one kind of water channels may play a role in preservation of alveolar e...

journal_title：Diagnostic pathology

authors： She J,Bi J,Tong L,Song Y,Bai C

更新日期：2013-11-25 00:00:00