NUT expression in primary lung tumours.

abstract：:Primary involvement of skeletal muscle is a very rare event in ALK-1 positive anaplastic large cell lymphoma (ALCL). We describe a case of a 10-year old boy presenting with a three week history of pain and a palpable firm swelling at the dorsal aspect of the left thigh. Histological examination of the lesion revealed ...

journal_title：Diagnostic pathology

authors： Gaiser T,Geissinger E,Schattenberg T,Scharf HP,Dürken M,Dinter D,Rosenwald A,Marx A

更新日期：2012-04-12 00:00:00

abstract：BACKGROUND:Metadherin (MTDH) has been reported to be associated with cancer progression in various types of human cancers including breast cancer. Whether MTDH contributes to carcinogenesis of breast cancer is still unknown. In the present study, we investigated the expression of MTDH in normal, UDH (usual ductal hyper...

journal_title：Diagnostic pathology

authors： Su P,Zhang Q,Yang Q

更新日期：2010-06-18 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) remains a major worldwide cause of cancer-related morbidity and mortality largely due to the insidious onset of the disease. The current clinical procedures utilized for disease diagnosis are invasive, unpleasant, and inconvenient. Hence, the need for simple blood tests that could be ...

journal_title：Diagnostic pathology

authors： Fan NJ,Kang R,Ge XY,Li M,Liu Y,Chen HM,Gao CF

更新日期：2014-03-12 00:00:00

abstract：BACKGROUND:High grade basal-like breast carcinomas are triple negative, express basal cytokeratins, and are known for the overall poor prognosis and aggressive behavior. HPV related multiphenotypic sino-nasal carcinoma has overlapping histology with basal-like breast carcinomas, but carry the defining feature of associ...

journal_title：Diagnostic pathology

authors： Oramas DM,Bell D,Middleton LP

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:Spontaneous isolated dissection of the superior mesenteric artery (SMA) can lead to bowel ischemia, aneurysm rupture, or even death. Studies have suggested that mechanical or hemodynamic stress on the vascular wall of the SMA may be a contributor, but its pathogenesis is unclear. CASE PRESENTATION:A 57-year...

journal_title：Diagnostic pathology

authors： Akuzawa N,Kurabayashi M,Suzuki T,Yoshinari D,Kobayashi M,Tanahashi Y,Makita F,Saito R

更新日期：2017-10-16 00:00:00

abstract：:Central neurocytoma/extraventricular neurocytoma is a central nervous system (CNS) tumor composed of uniform round cells with neuronal differentiation. The typical lesions of central neurocytoma/extraventricular neurocytoma are at the interventricular foramen of the lateral ventricles (central neurocytoma) or brain pa...

journal_title：Diagnostic pathology

authors： Yu JH,Yang LH,Lin XY,Dai SD,Qiu XS,Wang EH

更新日期：2015-09-17 00:00:00

abstract：UNLABELLED:A 34-year-old female, with a history of continued asbestos exposure, presented with a papillary peritoneal mesothelioma with a diffuse, prominent clear foamy cell change, with microvacuolation in its papillary lining, that expressed cytokeratins 7, 5/6 and calretinin as well as nuclear WT-1 and apical membra...

journal_title：Diagnostic pathology

authors： Stolnicu S,Quiñonez E,Boros M,Molnar C,Dulcey I,Nogales FF

更新日期：2013-09-25 00:00:00

abstract：:Telepathology, the practice of pathology at a long distance, has advanced continuously since 1986. Today, fourth-generation telepathology systems, so-called virtual slide telepathology systems, are being used for education applications. Both conventional and innovative surgical pathology diagnostic services are being ...

journal_title：Diagnostic pathology

authors： Ayad E

更新日期：2011-03-30 00:00:00

abstract：BACKGROUND:Ischemia/reperfusion (I/R) injury of heart is one of the major causes of acute cardiac injury, which may result in worsening or even loss of heart function. With novel microRNAs being evolutionarily discovered, numbers of them remained functionally unknown. We aimed to discover novel microRNAs with therapeut...

journal_title：Diagnostic pathology

authors： Chen Y,Ye X,Yan F

更新日期：2019-10-31 00:00:00

abstract：BACKGROUND:Rhabdoid colorectal tumor (RCT) is a rare, highly aggressive neoplasm recurrent in elderly patients, commonly at the caecum. The molecular mechanisms underlying RCT pathogenesis remain poorly elucidated. The differential diagnosis is with the malignant rhabdoid tumors of infancy characterized by genetic inac...

journal_title：Diagnostic pathology

authors： Pancione M,Remo A,Sabatino L,Zanella C,Votino C,Fucci A,Di Blasi A,Lepore G,Daniele B,Fenizia F,Molinari E,Normanno N,Manfrin E,Vendraminelli R,Colantuoni V

更新日期：2013-02-20 00:00:00

abstract：:Insights into the molecular underpinnings of primary central nervous system tumors have radically changed the approach to tumor diagnosis and classification. Diagnostic emphasis has shifted from the morphology of a tumor under the microscope to an integrated approach based on morphologic and molecular features, includ...

journal_title：Diagnostic pathology

authors： Wood MD,Halfpenny AM,Moore SR

更新日期：2019-04-09 00:00:00

abstract：BACKGROUND:c-MET is an oncogene protein that plays important role in gastric carcinogenesis and has been introduced as a prognostic marker and potential therapeutic target. The aim of this study was to evaluate the frequency of c-MET overexpression and its relationship with clinicopathological variables in gastric canc...

journal_title：Diagnostic pathology

authors： Sotoudeh K,Hashemi F,Madjd Z,Sadeghipour A,Molanaei S,Kalantary E

更新日期：2012-05-28 00:00:00

abstract：:This study examined the effect of tissue section thickness and consistency--parameters outside the direct control of the imaging devices themselves--on WSI capture speed and image quality. Preliminary data indicates that thinner, more consistent tissue sectioning (such as those produced by automated tissue sectioning ...

journal_title：Diagnostic pathology

authors： Yagi Y,Gilbertson JR

更新日期：2008-07-15 00:00:00

abstract：BACKGROUND/OBJECTIVE:Metastatic adenocarcinoma from an unknown primary site is a common clinical problem. Determining the cytokeratin (CK) 7/CK20 pattern of tumors is one of the most helpful procedures for this purpose since the CK7-/CK20+ pattern is typical of colorectal adenocarcinomas. CDX2, a critical nuclear trans...

journal_title：Diagnostic pathology

authors： Bayrak R,Haltas H,Yenidunya S

更新日期：2012-01-23 00:00:00

abstract：:Two studies recently reported around 10% of EGFR activating mutations in triple negative breast cancers from Asian patients. However, we did not find any EGFR activating mutation in a series of 229 breast tumor samples from European patients. Like in lung cancer, the EGFR mutation profiles seem to be related to the et...

journal_title：Diagnostic pathology

authors： Lamy PJ,Jacot W

更新日期：2012-02-01 00:00:00

abstract：:Bronchoalveolar lavage (BAL) is a useful diagnostic tool in interstitial lung diseases (ILD). However, differential cell counts are often non specific and immunocytochemistry is time consuming. Staining of glycoproteins by periodic acid Schiff (PAS) reaction may help in discriminating different forms of ILD. In additi...

journal_title：Diagnostic pathology

authors： Hauber HP,Zabel P

更新日期：2009-04-23 00:00:00

abstract：BACKGROUND:The optimal course of clinical follow-up after a diagnosis of breast papillary lesion on a core needle biopsy (CNB) remains elusive. In particular, no reports in literature have addressed this question in African-American population. We describe our experience with breast papillary lesions in a primarily Afr...

journal_title：Diagnostic pathology

authors： Wang H,Tsang P,D'Cruz C,Clarke K

更新日期：2014-04-24 00:00:00

abstract：BACKGROUND:The microRNAs present a class of non-coding RNAs which are usually implicated in tumor biology. Recent report has unraveled that a novel member of microRNA family called miR-1246. However, the functional role and molecular mechanisms of miR-1246 in non-small cell lung cancer (NSCLC) is still elusive. METHOD...

journal_title：Diagnostic pathology

authors： Huang W,Li H,Luo R

更新日期：2015-07-25 00:00:00

abstract：BACKGROUND:Rapid ("warm") autopsies of patients with advanced metastatic cancer provide important insight into the natural history, pathobiology and histomorphology of disease in treatment-resistant tumors. Plasmacytoid urothelial carcinoma (PUC) is a rare variant of urothelial carcinoma characterized by neoplastic cel...

journal_title：Diagnostic pathology

authors： Simon CT,Skala SL,Killen PD,Siddiqui J,Cao X,Qiao Y,Al-Ahmadie H,Camelo-Piragua SI,Jentzen J,Chinnaiyan AM,Dhanasekaran SM,Reichert ZR,Mehra R

更新日期：2019-10-21 00:00:00

abstract：BACKGROUND:The uterine endometrial polyp (EMP) has a potential risk of developing malignant tumors especially in postmenopausal women. These malignancies include endometrial intraepithelial carcinoma (EIC). PATIENTS AND METHODS:Eight patients with EIC in the EMP, who were postmenopausal with ages ranging from 49 to 76...

journal_title：Diagnostic pathology

authors： Yasuda M,Katoh T,Hori S,Suzuki K,Ohno K,Maruyama M,Matsui N,Miyazaki S,Ogane N,Kameda Y

更新日期：2013-02-15 00:00:00

abstract：BACKGROUND:Malignant gastrointestinal neuroectodermal tumor (GNET) is an extremely rare entity that was first described by Zambrano et al. in 2003 as "Clear cell sarcoma-like tumor of the gastrointestinal tract". It shares some of the histological features of clear cell sarcoma (CCS) but lacks the immunohistochemical r...

journal_title：Diagnostic pathology

authors： Alyousef MJ,Alratroot JA,ElSharkawy T,Shawarby MA,Al Hamad MA,Hashem TM,Alsayyah A

更新日期：2017-03-20 00:00:00

abstract：BACKGROUND:To quantify the effect of cruciferous vegetable consumption on the incidence of ovarian cancer by meta-analyzing the existing observational studies and provides quantitative and high-level evidence. METHODS:A detailed literature search of Medline and EMBASE for all relevant papers published. A meta-analysis...

journal_title：Diagnostic pathology

authors： Han B,Li X,Yu T

更新日期：2014-01-20 00:00:00

abstract：UNLABELLED:As rare condition, mucoepidermoid carcinoma may occur in liver although its etiology and pathogenesis is still unclear. We report here a case of intrahepatic mucoepidermoid carcinoma misdiagnosed as cholangiocarcinoma and squamous cell carcinoma by preoperative radiologic and intraoperative histological exam...

journal_title：Diagnostic pathology

authors： Guo XQ,Li B,Li Y,Tian XY,Li Z

更新日期：2014-01-29 00:00:00

abstract：BACKGROUND:Kombucha, a fermented tea (KT) is claimed to possess many beneficial properties. The aim of this study was to evaluate clinical and histopathological alterations of Kombucha tea and Nitrofurazone on cutaneous full-thickness wounds healing in rat. METHODS:In present study 24 Wister -albino rats weighing 150-...

journal_title：Diagnostic pathology

authors： Barati F,Javanbakht J,Adib-Hashemi F,Hosseini E,Safaeie R,Rajabian M,Razmjoo M,Sedaghat R,Aghamohammad Hassan M

更新日期：2013-07-17 00:00:00

abstract：BACKGROUND:The novel pandemic A (H1N1) pdm09 virus was first identified in Mexico in April 2009 and since then it spread worldwide over a short period of time. Although the virus infection is generally associated with mild disease and a relatively low mortality, it is projected that mutations in specific regions of the...

journal_title：Diagnostic pathology

authors： Moussi AE,Kacem MA,Pozo F,Ledesma J,Cuevas MT,Casas I,Slim A

更新日期：2013-07-31 00:00:00

abstract：BACKGROUND:Ki67 is currently the proliferation biomarker of choice, with both prognostic and predictive value in breast cancer. A lack of consensus regarding Ki67 use in pre-analytical, analytical and post-analytical practice may hinder its formal acceptance in the clinical setting. METHODS:One hundred breast cancer s...

journal_title：Diagnostic pathology

authors： Romero Q,Bendahl PO,Fernö M,Grabau D,Borgquist S

更新日期：2014-06-16 00:00:00

abstract：BACKGROUND:Identification of predictive molecular alterations in lung adenocarcinoma is essential for accurate therapeutic decisions. Although several molecular approaches are available, a number of issues, including tumor heterogeneity, frequent material scarcity, and the large number of loci to be investigated, must ...

journal_title：Diagnostic pathology

authors： Bonaparte E,Pesenti C,Fontana L,Falcone R,Paganini L,Marzorati A,Ferrero S,Nosotti M,Mendogni P,Bareggi C,Sirchia SM,Tabano S,Bosari S,Miozzo M

更新日期：2018-01-12 00:00:00

abstract：BACKGROUND:Morphine has been widely used as a clinical anesthetic and analgesic. However, abuse of morphine might result in psychological and physiological dependence. Previous studies have indicated that memory mechanisms play critical roles in morphine dependence. METHODS:Morphine dependence was established in mice ...

journal_title：Diagnostic pathology

authors： Ye J,Yang Z,Li C,Cai M,Zhou D,Zhang Q,Wei Y,Wang T,Liu Y

更新日期：2014-07-10 00:00:00

abstract：BACKGROUND:Histologic grade is the most important predictor of the clinical outcome of non-muscle invasive (Ta, T1) papillary urothelial carcinoma (NMIPUCa), but its ambiguous criteria diminish its power to predict recurrence/progression for individual patients. We attempted to find an objective and reproducible histol...

journal_title：Diagnostic pathology

authors： Kwon JE,Cho NH,Choi YJ,Lim SD,Cho YM,Jun SY,Park S,Kim YA,Kim SS,Choe MS,Lee JD,Kang DY,Ro JY,Kim HJ

更新日期：2017-07-24 00:00:00

abstract：BACKGROUND:IL4Rα and IL13Rα1 are constituents of the type II IL4 receptor. Recently, IL4Rα and IL13Rα1 were reported to have roles in cancer progression and suggested as potential prognostic markers. However, studies on IL4Rα and IL13Rα1 in soft-tissue sarcomas have been limited. METHODS:This study investigated the im...

journal_title：Diagnostic pathology

authors： Kim KM,Hussein UK,Park SH,Moon YJ,Zhang Z,Ahmed AG,Ahn AR,Park HS,Kim JR,Jang KY

更新日期：2021-01-09 00:00:00