The clinicopathologic association of c-MET overexpression in Iranian gastric carcinomas; an immunohistochemical study of tissue microarrays.

abstract：:Insights into the molecular underpinnings of primary central nervous system tumors have radically changed the approach to tumor diagnosis and classification. Diagnostic emphasis has shifted from the morphology of a tumor under the microscope to an integrated approach based on morphologic and molecular features, includ...

journal_title：Diagnostic pathology

authors： Wood MD,Halfpenny AM,Moore SR

更新日期：2019-04-09 00:00:00

abstract：BACKGROUND:Assessment of hemoglobin is one of the most reliable indicators for anemia, and is widely used to screen for anemia among pregnant women. The HemoCue® has been widely used for as a point-of-care device for hemoglobin estimation in health facilities. Previous studies showed contradictory results regarding the...

journal_title：Diagnostic pathology

authors： Adam I,Ahmed S,Mahmoud MH,Yassin MI

更新日期：2012-03-21 00:00:00

abstract：BACKGROUND:High grade basal-like breast carcinomas are triple negative, express basal cytokeratins, and are known for the overall poor prognosis and aggressive behavior. HPV related multiphenotypic sino-nasal carcinoma has overlapping histology with basal-like breast carcinomas, but carry the defining feature of associ...

journal_title：Diagnostic pathology

authors： Oramas DM,Bell D,Middleton LP

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:Nuclear protein in testis (NUT) midline carcinomas (NMC) are rare, highly aggressive epithelial neoplasms, characterised by protein expression of NUT-fusion proteins which reflects the genetic translocation between chromosome 15 and 19. NMC occurs mainly in midline structures, but there are reports regarding...

journal_title：Diagnostic pathology

authors： Lund-Iversen M,Grøholt KK,Helland Å,Borgen E,Brustugun OT

更新日期：2015-09-05 00:00:00

abstract：BACKGROUND:Several studies reported the dysregulation of miR-541 in the progression of some human malignancies. Osteosarcoma (OS) is one of the most common primary malignant bone tumors. This study aimed to assess the expression and clinical significance of miR-541 in OS patients and explore the biological function of ...

journal_title：Diagnostic pathology

authors： Liu C,Yi X

更新日期：2020-07-24 00:00:00

abstract：BACKGROUND:Esophageal cancer is one of the leading causes of cancer related deaths among the Iranians. There is still a high ratio of mortality and low 5 years survival which are related to the late onset and diagnosis. Majority of patients refer for the treatment in advanced stages of tumor progression. MAIN BODY:It ...

journal_title：Diagnostic pathology

authors： Abbaszadegan MR,Keyvani V,Moghbeli M

更新日期：2019-08-31 00:00:00

abstract：BACKGROUND:The novel pandemic A (H1N1) pdm09 virus was first identified in Mexico in April 2009 and since then it spread worldwide over a short period of time. Although the virus infection is generally associated with mild disease and a relatively low mortality, it is projected that mutations in specific regions of the...

journal_title：Diagnostic pathology

authors： Moussi AE,Kacem MA,Pozo F,Ledesma J,Cuevas MT,Casas I,Slim A

更新日期：2013-07-31 00:00:00

abstract：INTRODUCTION:Necrobiosis lipoidica diabeticorum is a rare disease of unclear etiology, that occurs in about 1% of diabetic patients. CASE REPORT:We present case of granulomatosis disciformis chronica et progressiva Miescher with good response to systemic corticosteroids therapy.Patient 45 years old woman, with primary...

journal_title：Diagnostic pathology

authors： Bergler-Czop B,Brzezińska-Wcisło L,Rogala-Poborska I

更新日期：2009-08-28 00:00:00

abstract：BACKGROUND:Crowdsourcing, i.e., the outsourcing of tasks typically performed by a few experts to a large crowd as an open call, has been shown to be reasonably effective in many cases, like Wikipedia, the Chess match of Kasparov against the world in 1999, and several others. The aim of the present paper is to describe ...

journal_title：Diagnostic pathology

authors： Della Mea V,Maddalena E,Mizzaro S,Machin P,Beltrami CA

更新日期：2014-01-01 00:00:00

abstract：UNLABELLED:As rare condition, mucoepidermoid carcinoma may occur in liver although its etiology and pathogenesis is still unclear. We report here a case of intrahepatic mucoepidermoid carcinoma misdiagnosed as cholangiocarcinoma and squamous cell carcinoma by preoperative radiologic and intraoperative histological exam...

journal_title：Diagnostic pathology

authors： Guo XQ,Li B,Li Y,Tian XY,Li Z

更新日期：2014-01-29 00:00:00

abstract：BACKGROUND:Prostate cancer patients with rectal involvement are rare, and the factors associated with the survival of these patients are yet to be elucidated. PATIENTS AND METHODS:We collected data on patients who were admitted to our hospital for prostate cancer in the last thirteen years and of those in studies in t...

journal_title：Diagnostic pathology

authors： Wang H,Yao Y,Li B

更新日期：2014-02-20 00:00:00

abstract：:Concurrent hematologic malignancies are relatively rare. We encountered a case of concurrent acute myeloid leukemia (AML) and T lymphoblastic lymphoma. The bone marrow chromosome analysis showed the karyotype 46, XY, t(5;12)(q33;p13), which indicated presence of PDGFRB gene translocations. Therefore, this disease belo...

journal_title：Diagnostic pathology

authors： Chang H,Chuang WY,Sun CF,Barnard MR

更新日期：2012-02-22 00:00:00

abstract：BACKGROUND:Somatostatin receptor 2 (SSTR2) encodes somatostatin receptor that can inhibit the cell proliferation of solid tumors. Promoter hypermethylation is likely to silence the expression of SSTR2. The goal of our study was to investigate the association between SSTR2 promoter methylation and the risk and progressi...

journal_title：Diagnostic pathology

authors： Shen Z,Chen X,Li Q,Zhou C,Li J,Ye H,Duan S

更新日期：2016-01-22 00:00:00

abstract：INTRODUCTION:Nemaline myopathy is a rare genetic muscle disorder defined by the presence of nemaline rods in the muscle fibre sarcoplasm. Congenital nemaline myopathy is the most serious form of the disease's spectrum. CASE PRESENTATION:The affected newborn has no spontaneous movement, fractures at birth and respirato...

journal_title：Diagnostic pathology

authors： Waisayarat J,Suriyonplengsaeng C,Khongkhatithum C,Rochanawutanon M

更新日期：2015-04-16 00:00:00

abstract：:A case of prenatally diagnosed, giant cord hemangioma is reported, which was accompanied by the elevation of maternal serum alpha-fetoprotein (MS-AFP) and human chorionic gonadotropin (MS-hCG) levels. A 30-year-old woman without a previous history of gravida or para, presented with intermittent abdominal pain at 26 we...

journal_title：Diagnostic pathology

authors： Hara K,Fukumura Y,Saito T,Arakawa A,Okabe H,Takeda S,Yao T

更新日期：2015-09-04 00:00:00

abstract：BACKGROUND:To evaluate the clinical utility of LIM Domain Only 2 (LMO2) negative and CD38 positive in diagnosis of Burkitt lymphoma (BL). METHODS:LMO2 and CD38 expression determined by immunohistochemistry in 75 BL, 12 High-grade B-cell lymphoma, NOS (HGBL,NOS) and 3 Burkitt-like lymphomas with the 11q aberration. RE...

journal_title：Diagnostic pathology

authors： Liu Y,Bian T,Zhang Y,Zheng Y,Zhang J,Zhou X,Xie J

更新日期：2019-09-04 00:00:00

abstract：:Perivascular epithelioid cell tumor (PEComa) is a rare entity originating from mesenchymal tissue, which stains for both melanocytic and smooth muscle markers. We would like to present an unusual case of the PEComa of the mesentery which was unexpected discovery in a female patient with colonic adenocarcinoma. The tum...

journal_title：Diagnostic pathology

authors： Wejman J,Nowak K,Gielniewska L,Komorowska M,Dąbrowski W

更新日期：2015-04-18 00:00:00

abstract：BACKGROUND:The outbreak of a novel coronavirus since December 2019, became an emergency of major international concern. As of June 21, 2020, the SARS-CoV-2 pandemic has caused 8,769,844 confirmed infections with 463,745 fatal cases worldwide. The SARS-CoV-2 outbreak is a major challenge for clinicians. In our clinic, w...

journal_title：Diagnostic pathology

authors： Zhai P,Ding Y,Li Y

更新日期：2020-06-29 00:00:00

abstract：:Endocervicosis in the urinary bladder is a rare benign condition. We present a case in a 37-year-old woman with classical clinical and pathological features of endocervicosis. The unusual observation of endocervical-like mucinous epithelium in continuity with the urothelium in addition to fully developed endocervicosi...

journal_title：Diagnostic pathology

authors： Cheah PL,Looi LM,Lee GE,Teoh KH,Mun KS,Nazarina AR

更新日期：2011-06-23 00:00:00

abstract：BACKGROUND:The histopathological subtype, nuclear grade and presence or absence of comedonecrosis are established as critical elements in the reporting of ductal carcinoma in situ (DCIS) of the breast. The aims of this study were to determine the frequencies of morphological subtypes of DCIS, nuclear grade and comedone...

journal_title：Diagnostic pathology

authors： Perez AA,Balabram D,Salles Mde A,Gobbi H

更新日期：2014-12-03 00:00:00

abstract：BACKGROUND:Esophageal squamous cell carcinoma (ESCC) still remains intractable disease with few therapeutic options. Programmed death-ligand 1 (PD-L1), which is essential for immune evasion, is involved in the pathogenesis of ESCC and thus is a potential therapeutic target. PIK3CA, KRAS, and BRAF mutations, microsatell...

journal_title：Diagnostic pathology

authors： Lee HK,Kwon MJ,Ra YJ,Lee HS,Kim HS,Nam ES,Cho SJ,Park HR,Min SK,Seo J,Choe JY,Min KW,Kang SY

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND:Isolated hypothalamic-pituitary Langerhans cell histiocytosis (HPLCH) is very rare. We investigated the clinicopathological characteristics, endocrine function changes, BRAFV600E mutations and treatments of isolated HPLCH. METHODS:We identified seven patients with isolated HPLCH by reviewing the clinical an...

journal_title：Diagnostic pathology

authors： Huo Z,Lu T,Liang Z,Ping F,Shen J,Lu J,Ma W,Zhao D,Zhong D

更新日期：2016-10-19 00:00:00

abstract：BACKGROUND:To quantify the effect of cruciferous vegetable consumption on the incidence of ovarian cancer by meta-analyzing the existing observational studies and provides quantitative and high-level evidence. METHODS:A detailed literature search of Medline and EMBASE for all relevant papers published. A meta-analysis...

journal_title：Diagnostic pathology

authors： Han B,Li X,Yu T

更新日期：2014-01-20 00:00:00

abstract：:Two studies recently reported around 10% of EGFR activating mutations in triple negative breast cancers from Asian patients. However, we did not find any EGFR activating mutation in a series of 229 breast tumor samples from European patients. Like in lung cancer, the EGFR mutation profiles seem to be related to the et...

journal_title：Diagnostic pathology

authors： Lamy PJ,Jacot W

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:To investigate the therapeutic effect of p38-MAPK inhibitor, SB203580, on dry eye in a mouse model of Sjögren's syndrome (MRL/lpr mice). METHODS:18 female BALB/c mice and 44 female MRL/lpr mice were included. Mice were randomly assigned to the control or treatment group. The expression of phospho-p38 MAPK i...

journal_title：Diagnostic pathology

authors： Ma X,Zou J,He L,Zhang Y

更新日期：2014-01-20 00:00:00

abstract：BACKGROUND:High altitude pulmonary edema (HAPE) affects individuals and is characterized by alveolar flooding with protein-rich edema as a consequence of blood-gas barrier disruption. In this study, we hypothesized that aquaporin 5 (AQP5) which is one kind of water channels may play a role in preservation of alveolar e...

journal_title：Diagnostic pathology

authors： She J,Bi J,Tong L,Song Y,Bai C

更新日期：2013-11-25 00:00:00

abstract：:Tumours of ovarian-epithelial type of the testis, including serous borderline tumours, represent very rare entities. They are identical to the surface epithelial tumours of the ovary and have been reported in patients from 14 to 68 years of age. We describe two cases of a 46- and a 39-year old man with incidental find...

journal_title：Diagnostic pathology

authors： Bürger T,Schildhaus HU,Inniger R,Hansen J,Mayer P,Schweyer S,Radzun HJ,Ströbel P,Bremmer F

更新日期：2015-07-22 00:00:00

abstract：BACKGROUND:Primary central nervous system (CNS) diffuse large B-cell lymphoma (DLBCL) is a rare intracranial tumor, defined as DLBCL arising from the brain, spinal cord, leptomeninges and eye, with an overall annual incidence of 5 cases per million. The primary CNS anaplastic variant of DLBCL (A-DLBCL) is even less com...

journal_title：Diagnostic pathology

authors： Xu T,Jia Q,Wang Y,Liu Y,Han D,Li P,Ma J,Fan L,Yan Q,Guo S,Li M,Wang Z

更新日期：2019-05-20 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) remains a major worldwide cause of cancer-related morbidity and mortality largely due to the insidious onset of the disease. The current clinical procedures utilized for disease diagnosis are invasive, unpleasant, and inconvenient. Hence, the need for simple blood tests that could be ...

journal_title：Diagnostic pathology

authors： Fan NJ,Kang R,Ge XY,Li M,Liu Y,Chen HM,Gao CF

更新日期：2014-03-12 00:00:00

abstract：BACKGROUND:Discordant lymphoma is defined by the simultaneous presence of two or more distinct types of lymphomas at different anatomic sites. With fewer than 20 studies reporting cases of discordant lymphoma to date, the incidence of this condition is believed to be very low. CASE PRESENTATION:Here, we report a case ...

journal_title：Diagnostic pathology

authors： Zhang C,Yi Y,Chen C,Wang J,Liu Z

更新日期：2015-12-29 00:00:00