Immunohistochemical analysis of Metadherin in proliferative and cancerous breast tissue.

abstract：BACKGROUND:Carbonic anhydrase IX is a member of α-carbonic anhydrases that is preferentially expressed in solid tumors. It enables bicarbonate transport across the plasma membrane, neutralizing intracellular pH and conferring to cancer cells a survival advantage in hypoxic/acidic microenvironments. Overexpression of ca...

journal_title：Diagnostic pathology

authors： Ambrosio MR,Di Serio C,Danza G,Rocca BJ,Ginori A,Prudovsky I,Marchionni N,Del Vecchio MT,Tarantini F

更新日期：2016-05-25 00:00:00

abstract：:Complement C4d component deposition in kidney allograft biopsies is an established marker of antibody-mediated rejection. In the Banff 07 classification of renal allograft pathology, semi-quantitative evaluation of the proportion of C4d-positive peritubular capilaries (PTC) is used. We aimed to explore the potential o...

journal_title：Diagnostic pathology

authors： Brazdziute E,Laurinavicius A

更新日期：2011-03-30 00:00:00

abstract：BACKGROUND:To investigate the therapeutic effect of p38-MAPK inhibitor, SB203580, on dry eye in a mouse model of Sjögren's syndrome (MRL/lpr mice). METHODS:18 female BALB/c mice and 44 female MRL/lpr mice were included. Mice were randomly assigned to the control or treatment group. The expression of phospho-p38 MAPK i...

journal_title：Diagnostic pathology

authors： Ma X,Zou J,He L,Zhang Y

更新日期：2014-01-20 00:00:00

abstract：:Telepathology, the practice of pathology at a long distance, has advanced continuously since 1986. Today, fourth-generation telepathology systems, so-called virtual slide telepathology systems, are being used for education applications. Both conventional and innovative surgical pathology diagnostic services are being ...

journal_title：Diagnostic pathology

authors： Ayad E

更新日期：2011-03-30 00:00:00

abstract：UNLABELLED:Since first reported in 1986, 14 cases of extrauterine adenomyoma have been reported in the English literature, most often occurring in the ovaries. In this report, we present the first case of extrauterine adenomyoma involving the liver in a 29-year-old woman who presented with a 2-year history of low back ...

journal_title：Diagnostic pathology

authors： Huanwen W,Hui Z,Xiaowei X,Zhaohui L

更新日期：2013-08-05 00:00:00

abstract：:Cutaneous apocrine carcinoma (AC) is a rare adnexal neoplasm that histologically can mimic breast carcinoma metastatic to the skin or apocrine carcinoma arising in ectopic breast tissue. As extremely rare condition, neuroendocrine differentiation may be observed in AC although its etiology and pathogenesis is still un...

journal_title：Diagnostic pathology

authors： Li Y,Chen LL,Li B,Tian XY,Li Z

更新日期：2015-06-10 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) remains a major worldwide cause of cancer-related morbidity and mortality largely due to the insidious onset of the disease. The current clinical procedures utilized for disease diagnosis are invasive, unpleasant, and inconvenient. Hence, the need for simple blood tests that could be ...

journal_title：Diagnostic pathology

authors： Fan NJ,Kang R,Ge XY,Li M,Liu Y,Chen HM,Gao CF

更新日期：2014-03-12 00:00:00

abstract：UNLABELLED:Perivascular epithelioid cell tumors (PEComas) encompass a group of rare mesenchymal neoplasms, which typically have a perivascular location with dual melanocytic and muscular differentiation. They are found in a variety of localizations, though lesions in the liver are exceedingly rare. Because of their rar...

journal_title：Diagnostic pathology

authors： Ameurtesse H,Chbani L,Bennani A,Toughrai I,Beggui N,Kamaoui I,Elfatemi H,Harmouch T,Amarti A

更新日期：2014-07-17 00:00:00

abstract：:Perivascular epithelioid cell (PEC) tumors (PEComas) are a family of related mesenchymal tumors composed of PECs which co-express melanocytic and smooth muscle markers. Although their distinctive histologic, immunohistochemical, ultrastructural, and genetic features have been clearly demonstrated, their histogenesis a...

journal_title：Diagnostic pathology

authors： Fang CL,Lin YH,Chen WY

更新日期：2012-09-03 00:00:00

abstract：BACKGROUND:Crystalloid podocytopathy with focal segmental glomerulosclerosis in plasma cell myeloma (PCM) is rare. CASE PRESENTATION:We present a case of crystalline deposition in the bone marrow (BM) and various renal cells with only proteinuria as a symptom. As workup for proteinuria, a renal biopsy sample was obtai...

journal_title：Diagnostic pathology

authors： Jeon YL,Lee WI,Choi Y,Kang SY,Kim MH,Lim SJ,Lee SH

更新日期：2015-12-16 00:00:00

abstract：:Sclerosing rhabdomyosarcoma (SRMS) is an infrequent variant of rhabdomyosarcoma characterized by extensive intercellular hyaline fibrosis. We report the case of a 37 year-old male with a 9 x 6 cm SRMS on the right elbow. Histologically, the tumor showed an abundant extracellular hyaline matrix with extratumoral vascul...

journal_title：Diagnostic pathology

authors： Martorell M,Ortiz CM,Garcia JA

更新日期：2010-08-11 00:00:00

abstract：BACKGROUND:Appendiceal parasites can cause symptoms of appendiceal pain, independent of microscopic evidence of acute inflammation. The diagnosis of a parasitic infestation is generally achieved only after the pathologic examination of the resected appendices. PATIENTS/METHODS:Pathology department records were reviewe...

journal_title：Diagnostic pathology

authors： Aydin O

更新日期：2007-05-24 00:00:00

abstract：:Insights into the molecular underpinnings of primary central nervous system tumors have radically changed the approach to tumor diagnosis and classification. Diagnostic emphasis has shifted from the morphology of a tumor under the microscope to an integrated approach based on morphologic and molecular features, includ...

journal_title：Diagnostic pathology

authors： Wood MD,Halfpenny AM,Moore SR

更新日期：2019-04-09 00:00:00

abstract：UNLABELLED:Atypical teratoid/rhabdoid tumors are rare and highly malignant central nervous system tumors. They have no specific radiological features and often present several histological components that make a problem in differential diagnosis with medulloblastoma and primitive neuroectodermal tumors. We present the ...

journal_title：Diagnostic pathology

authors： Mahdi Y,Kharmoum J,Alouan A,Elouarradi H,Elkhiyat I,Maher M,Benchrif MZ,Kili A,Daoudi R,Cherradi N

更新日期：2015-05-02 00:00:00

abstract：BACKGROUND:GATA-binding protein 3 (GATA3) has been identified as a sensitive marker for breast carcinoma but its sensitivity in primary genital extramammary Paget diseases (EMPDs) has not been well studied. METHODS:Here we investigated immunohistochemical expression of GATA3 in 72 primary genital EMPDs (35 from female...

journal_title：Diagnostic pathology

authors： Zhao M,Zhou L,Sun L,Song Y,Guo Y,Zhang X,Zhao F,Wang P,Yue J,Niu D,Li Z,Huang X,Kang Q,Jia L,Lai J,Cao D

更新日期：2017-07-10 00:00:00

abstract：BACKGROUND:To evaluate the clinical utility of LIM Domain Only 2 (LMO2) negative and CD38 positive in diagnosis of Burkitt lymphoma (BL). METHODS:LMO2 and CD38 expression determined by immunohistochemistry in 75 BL, 12 High-grade B-cell lymphoma, NOS (HGBL,NOS) and 3 Burkitt-like lymphomas with the 11q aberration. RE...

journal_title：Diagnostic pathology

authors： Liu Y,Bian T,Zhang Y,Zheng Y,Zhang J,Zhou X,Xie J

更新日期：2019-09-04 00:00:00

abstract：BACKGROUND:It is not clear if sentinel lymph node (SLN) mapping can improve outcomes in patients with colorectal cancers. The purpose of this study was to determine the prognostic values of ex vivo sentinel lymph node (SLN) mapping and immunohistochemical (IHC) detection of SLN micrometastasis in colorectal cancers. M...

journal_title：Diagnostic pathology

authors： Wang FL,Shen F,Wan DS,Lu ZH,Li LR,Chen G,Wu XJ,Ding PR,Kong LH,Pan ZZ

更新日期：2012-06-22 00:00:00

abstract：BACKGROUND:Metastatic spread of tumor through lymphatic vasculature is an important adverse prognostic factor in a variety of human cancer and tumor lymphangiogenesis requires the interplay of several growth factors. Platelet-derived growth factor (PDGF)-BB and vascular endothelial growth factor (VEGF)-C are two import...

journal_title：Diagnostic pathology

authors： Liu J,Liu C,Qiu L,Li J,Zhang P,Sun Y

更新日期：2014-06-27 00:00:00

abstract：UNLABELLED:A 34-year-old female, with a history of continued asbestos exposure, presented with a papillary peritoneal mesothelioma with a diffuse, prominent clear foamy cell change, with microvacuolation in its papillary lining, that expressed cytokeratins 7, 5/6 and calretinin as well as nuclear WT-1 and apical membra...

journal_title：Diagnostic pathology

authors： Stolnicu S,Quiñonez E,Boros M,Molnar C,Dulcey I,Nogales FF

更新日期：2013-09-25 00:00:00

abstract：BACKGROUND:Gastrointestinal stromal tumors (GISTs), a type of mesenchymal tumor in the gastrointestinal tract, are believed to be closely associated with PDGFRA and C-KIT mutations. Schwannoma in the stomach, which is an unusual location, is a rare disorder. The simultaneous occurrence of the two diseases is rarer than...

journal_title：Diagnostic pathology

authors： Li Y,Teng Y,Wei X,Tian Z,Cao Y,Liu X,Duan X

更新日期：2019-10-23 00:00:00

abstract：BACKGROUND:Rapid ("warm") autopsies of patients with advanced metastatic cancer provide important insight into the natural history, pathobiology and histomorphology of disease in treatment-resistant tumors. Plasmacytoid urothelial carcinoma (PUC) is a rare variant of urothelial carcinoma characterized by neoplastic cel...

journal_title：Diagnostic pathology

authors： Simon CT,Skala SL,Killen PD,Siddiqui J,Cao X,Qiao Y,Al-Ahmadie H,Camelo-Piragua SI,Jentzen J,Chinnaiyan AM,Dhanasekaran SM,Reichert ZR,Mehra R

更新日期：2019-10-21 00:00:00

abstract：BACKGROUND:The optimal course of clinical follow-up after a diagnosis of breast papillary lesion on a core needle biopsy (CNB) remains elusive. In particular, no reports in literature have addressed this question in African-American population. We describe our experience with breast papillary lesions in a primarily Afr...

journal_title：Diagnostic pathology

authors： Wang H,Tsang P,D'Cruz C,Clarke K

更新日期：2014-04-24 00:00:00

abstract：BACKGROUND:The development of inhibitors against factor 8 (F8) is the most serious complication of replacement therapy with F8 in children with severe hemophilia. It was suggested that mismatched F8 replacement therapy may be a risk factor for the development of anti-factor F8 alloantibodies. Recently four single nucle...

journal_title：Diagnostic pathology

authors： Elmahmoudi H,Belhedi N,Jlizi A,Zahra K,Meddeb B,Ben Ammar Elgaaied A,Gouider E

更新日期：2011-06-17 00:00:00

abstract：BACKGROUND:Mesonephric-like adenocarcinoma (M-LAC) is a rare, recently described tumor occurring in the uterine corpus and ovary, which shares the same morphological and immunohistochemical features with the more common mesonephric adenocarcinoma (MAC), which mostly arises the uterine cervix. Despite the similarities b...

journal_title：Diagnostic pathology

authors： Dundr P,Gregová M,Němejcová K,Bártů M,Hájková N,Hojný J,Stružinská I,Fischerová D

更新日期：2020-07-21 00:00:00

abstract：OBJECTIVE:FNA is a simple, safe, cost-effective and accurate diagnostic tool for the initial screening of patients with thyroid nodules. The aims of this study were to determine the diagnostic utility of FNAC performed in our institution, assess the cytomorphologic features that contribute to diagnostic errors and prop...

journal_title：Diagnostic pathology

authors： Zhu Y,Song Y,Xu G,Fan Z,Ren W

更新日期：2020-01-03 00:00:00

abstract：BACKGROUND:A recently published transcript set is suitable for gene expression-based discrimination of normal colonic and colorectal cancer (CRC) biopsy samples. Our aim was to test the discriminatory power of the CRC-specific transcript set on independent biopsies and on formalin-fixed, paraffin-embedded (FFPE) tissue...

journal_title：Diagnostic pathology

authors： Kalmár A,Wichmann B,Galamb O,Spisák S,Tóth K,Leiszter K,Nielsen BS,Barták BK,Tulassay Z,Molnár B

更新日期：2015-07-25 00:00:00

abstract：:Concurrent hematologic malignancies are relatively rare. We encountered a case of concurrent acute myeloid leukemia (AML) and T lymphoblastic lymphoma. The bone marrow chromosome analysis showed the karyotype 46, XY, t(5;12)(q33;p13), which indicated presence of PDGFRB gene translocations. Therefore, this disease belo...

journal_title：Diagnostic pathology

authors： Chang H,Chuang WY,Sun CF,Barnard MR

更新日期：2012-02-22 00:00:00

abstract：BACKGROUND:High altitude pulmonary edema (HAPE) affects individuals and is characterized by alveolar flooding with protein-rich edema as a consequence of blood-gas barrier disruption. In this study, we hypothesized that aquaporin 5 (AQP5) which is one kind of water channels may play a role in preservation of alveolar e...

journal_title：Diagnostic pathology

authors： She J,Bi J,Tong L,Song Y,Bai C

更新日期：2013-11-25 00:00:00

abstract：UNLABELLED:Giant cell angioblastoma (GCAB) is an extremely rare soft tissue tumor of early childhood and only five cases have been described to date. As such the clinical, pathological, and prognostic features are poorly defined. We prensent here a new case of GCAB in bone of a child aged 4-years old. The lesion was co...

journal_title：Diagnostic pathology

authors： Mao RJ,Jiang ZM,Zhang HZ,Zhu XZ,Zhang QL

更新日期：2012-08-29 00:00:00

abstract：BACKGROUND:After introduction of the concept of critical value (CV) in laboratory medicine, some efforts were performed to define possible critical values in surgical pathology. Critical diagnosis (critical value) is a concept recently established in surgical pathology and is a challenging issue among pathologists and ...

journal_title：Diagnostic pathology

authors： Mireskandari M

更新日期：2008-07-12 00:00:00