Primary non-Hodgkin lymphoma of the tongue base: the clinicopathology of seven cases and evaluation of HPV and EBV status.

abstract：BACKGROUND:Reduced DNA repair capacities due to inherited polymorphisms may increase the susceptibility to cancers including gastric cancer. Previous studies investigating the association between Xeroderma Pigmentosum group C (XPC) gene polymorphisms and gastric cancer risk reported inconsistent results. We performed a...

journal_title：Diagnostic pathology

authors： Peng Q,Chen Z,Lu Y,Lao X,Mo C,Li R,Qin X,Li S

更新日期：2014-05-23 00:00:00

abstract：BACKGROUND:Rheumatoid Arthritis is a chronic disease leading to decreased quality of life with a rather variable response rate to Disease Modifying Anti Rheumatic Drugs. Methotrexate (MTX) is the gold standard therapy in Rheumatoid Arthritis. The Multidrug resistance Related Protein and Multi Drug Resistance protein 1,...

journal_title：Diagnostic pathology

authors： Micsik T,Lőrincz A,Gál J,Schwab R,Peták I

更新日期：2015-12-30 00:00:00

abstract：BACKGROUND:Adult granulosa cell tumors of the ovary (GCTs) are sex cord stromal tumors of unpredictable behaviour. Up to now, the prediction of the relapsing/malignant potential remains difficult. CD56 (NCAM) in GCTs was previously described in only two studies. However, the expression of its isoforms was not examined....

journal_title：Diagnostic pathology

authors： Völker HU,Engert S,Cramer A,Schmidt M,Kämmerer U,Müller-Hermelink HK,Gattenlöhner S

更新日期：2008-07-09 00:00:00

abstract：BACKGROUND:To investigate the therapeutic effect of p38-MAPK inhibitor, SB203580, on dry eye in a mouse model of Sjögren's syndrome (MRL/lpr mice). METHODS:18 female BALB/c mice and 44 female MRL/lpr mice were included. Mice were randomly assigned to the control or treatment group. The expression of phospho-p38 MAPK i...

journal_title：Diagnostic pathology

authors： Ma X,Zou J,He L,Zhang Y

更新日期：2014-01-20 00:00:00

abstract：BACKGROUND:Hyalinizing clear cell carcinoma (HCCC) is a rare low-grade tumour of salivary glands that was first described as a distinct entity in 1994 by Milchgrub et al. EWSR1-ATF1 fusion was found to be specific for this tumour. The majority of the reported cases of HCCC arise from minor salivary glands within the or...

journal_title：Diagnostic pathology

authors： AlAli BM,Alyousef MJ,Kamel AS,Al Hamad MA,Al-Bar MH,Algowiez RM

更新日期：2017-09-25 00:00:00

abstract：BACKGROUND:Mesonephric-like adenocarcinoma (M-LAC) is a rare, recently described tumor occurring in the uterine corpus and ovary, which shares the same morphological and immunohistochemical features with the more common mesonephric adenocarcinoma (MAC), which mostly arises the uterine cervix. Despite the similarities b...

journal_title：Diagnostic pathology

authors： Dundr P,Gregová M,Němejcová K,Bártů M,Hájková N,Hojný J,Stružinská I,Fischerová D

更新日期：2020-07-21 00:00:00

abstract：BACKGROUND:Esophageal squamous cell carcinoma (ESCC) still remains intractable disease with few therapeutic options. Programmed death-ligand 1 (PD-L1), which is essential for immune evasion, is involved in the pathogenesis of ESCC and thus is a potential therapeutic target. PIK3CA, KRAS, and BRAF mutations, microsatell...

journal_title：Diagnostic pathology

authors： Lee HK,Kwon MJ,Ra YJ,Lee HS,Kim HS,Nam ES,Cho SJ,Park HR,Min SK,Seo J,Choe JY,Min KW,Kang SY

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND:World Health Organization (WHO) criteria are commonly used to diagnose plasma cell myeloma (PCM); however, these criteria are complex and require several laboratory parameters. For differentiating reactive plasmacytosis from clonal plasma cell (PC) neoplasms such as PCM, it is important to accurately determi...

journal_title：Diagnostic pathology

authors： Nakayama S,Yokote T,Hirata Y,Iwaki K,Akioka T,Miyoshi T,Takayama A,Nishiwaki U,Masuda Y,Ikemoto T,Tanaka H,Nishimura Y,Tsuji M,Hanafusa T

更新日期：2012-09-28 00:00:00

abstract：BACKGROUND:To identify critical genes and biological pathways in acute lung injury (ALI), a comparative analysis of gene expression profiles of patients with ALI + sepsis compared with patients with sepsis alone were performed with bioinformatic tools. METHODS:GSE10474 was downloaded from Gene Expression Omnibus, incl...

journal_title：Diagnostic pathology

authors： Guo Z,Zhao C,Wang Z

更新日期：2014-09-26 00:00:00

abstract：BACKGROUND:Epithelioid schwannoma as a rare variant poses a challenge to all pathologists, as this uncommon entity is extremely difficult to conclusively diagnose by morphological analyses on a resected sample alone owing to its unique histopathological features. However, few papers have described the detailed clinicop...

journal_title：Diagnostic pathology

authors： Yamada S,Kirishima M,Hiraki T,Higashi M,Hatanaka K,Tanimoto A

更新日期：2017-01-19 00:00:00

abstract：OBJECTIVE:MicroRNA-100 (miR-100) has been demonstrated to be downregulated in bladder cancer tissues, and enforced expression of this miRNA may inhibit cell growth and colony formation of human bladder cancer 5637 cells in vitro. However, the clinical significance of miR-100 in human bladder cancer has not yet been elu...

journal_title：Diagnostic pathology

authors： Wang S,Xue S,Dai Y,Yang J,Chen Z,Fang X,Zhou W,Wu W,Li Q

更新日期：2012-11-22 00:00:00

abstract：BACKGROUND:Gastrointestinal stromal tumors (GISTs), a type of mesenchymal tumor in the gastrointestinal tract, are believed to be closely associated with PDGFRA and C-KIT mutations. Schwannoma in the stomach, which is an unusual location, is a rare disorder. The simultaneous occurrence of the two diseases is rarer than...

journal_title：Diagnostic pathology

authors： Li Y,Teng Y,Wei X,Tian Z,Cao Y,Liu X,Duan X

更新日期：2019-10-23 00:00:00

abstract：UNLABELLED:A 34-year-old female, with a history of continued asbestos exposure, presented with a papillary peritoneal mesothelioma with a diffuse, prominent clear foamy cell change, with microvacuolation in its papillary lining, that expressed cytokeratins 7, 5/6 and calretinin as well as nuclear WT-1 and apical membra...

journal_title：Diagnostic pathology

authors： Stolnicu S,Quiñonez E,Boros M,Molnar C,Dulcey I,Nogales FF

更新日期：2013-09-25 00:00:00

abstract：:Two studies recently reported around 10% of EGFR activating mutations in triple negative breast cancers from Asian patients. However, we did not find any EGFR activating mutation in a series of 229 breast tumor samples from European patients. Like in lung cancer, the EGFR mutation profiles seem to be related to the et...

journal_title：Diagnostic pathology

authors： Lamy PJ,Jacot W

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Extra-adrenal paraganglioma of the retroperitoneum with metastasis to the vertebra is very rare. To our knowledge this is the first report of this kind of disease in the literature. CASE PRESENTATION:Here, we present an oroginal case of paraganglioma of the retroperitoneum with metastasis to the abdominal v...

journal_title：Diagnostic pathology

authors： He J,Wang X,Zheng W,Zhao Y

更新日期：2013-03-28 00:00:00

abstract：:Telepathology, the practice of pathology at a long distance, has advanced continuously since 1986. Today, fourth-generation telepathology systems, so-called virtual slide telepathology systems, are being used for education applications. Both conventional and innovative surgical pathology diagnostic services are being ...

journal_title：Diagnostic pathology

authors： Ayad E

更新日期：2011-03-30 00:00:00

abstract：:Giant cell tumor (GCT) of bone is a locally destructive tumor that occurs predominantly in long bones of post-pubertal adolescents and young adults, where it occurs in the epiphysis. The majority are treated by aggressive curettage or resection. Vascular invasion outside the boundary of the tumor can be seen. Metastas...

journal_title：Diagnostic pathology

authors： Miller IJ,Blank A,Yin SM,McNickle A,Gray R,Gitelis S

更新日期：2010-09-22 00:00:00

abstract：BACKGROUND:The aim of this study was to analyze the frequency of Thyroid Transcription Factor (TTF)-1 expression in small cell lung cancer (SCLC) and its value for the diagnosis of SCLC, the response to first line treatment as well as the prognostic impact on overall survival (OS). METHODS:We analyzed a total of 294 p...

journal_title：Diagnostic pathology

authors： Misch D,Blum T,Boch C,Weiss T,Crolow C,Griff S,Mairinger T,Bauer TT,Kollmeier J

更新日期：2015-04-02 00:00:00

abstract：BACKGROUND:Prostate cancer patients with rectal involvement are rare, and the factors associated with the survival of these patients are yet to be elucidated. PATIENTS AND METHODS:We collected data on patients who were admitted to our hospital for prostate cancer in the last thirteen years and of those in studies in t...

journal_title：Diagnostic pathology

authors： Wang H,Yao Y,Li B

更新日期：2014-02-20 00:00:00

abstract：:This study examined the effect of tissue section thickness and consistency--parameters outside the direct control of the imaging devices themselves--on WSI capture speed and image quality. Preliminary data indicates that thinner, more consistent tissue sectioning (such as those produced by automated tissue sectioning ...

journal_title：Diagnostic pathology

authors： Yagi Y,Gilbertson JR

更新日期：2008-07-15 00:00:00

abstract：BACKGROUND:70-80% of sporadic endometrial carcinomas are defined as endometrioid carcinoma (EC). Early-stage, well differentiated endometrial carcinomas usually retain expression of estrogen and progesterone receptors (ER and PR, respectively), as advanced stage, poorly differentiated tumors often lack one or both of t...

journal_title：Diagnostic pathology

authors： Kreizman-Shefer H,Pricop J,Goldman S,Elmalah I,Shalev E

更新日期：2014-03-31 00:00:00

abstract：BACKGROUND:Evaluation of core needle biopsies (CNB) is a standard procedure for the diagnosis of breast cancer. However, tissue processing and image preparation is a time- consuming procedure and instant on-site availability of high-quality images could substantially improve the efficacy of the diagnostic procedure. Co...

journal_title：Diagnostic pathology

authors： Elfgen C,Papassotiropoulos B,Varga Z,Moskovszky L,Nap M,Güth U,Baege A,Amann E,Chiesa F,Tausch C

更新日期：2019-06-15 00:00:00

abstract：BACKGROUND:The novel pandemic A (H1N1) pdm09 virus was first identified in Mexico in April 2009 and since then it spread worldwide over a short period of time. Although the virus infection is generally associated with mild disease and a relatively low mortality, it is projected that mutations in specific regions of the...

journal_title：Diagnostic pathology

authors： Moussi AE,Kacem MA,Pozo F,Ledesma J,Cuevas MT,Casas I,Slim A

更新日期：2013-07-31 00:00:00

abstract：BACKGROUND:Discordant lymphoma is defined by the simultaneous presence of two or more distinct types of lymphomas at different anatomic sites. With fewer than 20 studies reporting cases of discordant lymphoma to date, the incidence of this condition is believed to be very low. CASE PRESENTATION:Here, we report a case ...

journal_title：Diagnostic pathology

authors： Zhang C,Yi Y,Chen C,Wang J,Liu Z

更新日期：2015-12-29 00:00:00

abstract：:Perivascular epithelioid cell tumor (PEComa) is a rare entity originating from mesenchymal tissue, which stains for both melanocytic and smooth muscle markers. We would like to present an unusual case of the PEComa of the mesentery which was unexpected discovery in a female patient with colonic adenocarcinoma. The tum...

journal_title：Diagnostic pathology

authors： Wejman J,Nowak K,Gielniewska L,Komorowska M,Dąbrowski W

更新日期：2015-04-18 00:00:00

abstract：BACKGROUND:The transcriptional co-activator, TAZ, is an important effector of the Hippo pathway and is critical for the development of human cancers. However, the expression and prognostic significance of TAZ in retinoblastoma is currently unclear. METHODS:TAZ expression was examined in 43 retinoblastoma samples by im...

journal_title：Diagnostic pathology

authors： Zhang Y,Xue C,Cui H,Huang Z

更新日期：2015-10-13 00:00:00

abstract：BACKGROUND:Advancing knowledge in molecular pathogenesis of hepatocellular carcinoma (HCC) opens up new horizons in the diagnostic, prognostic and therapeutic perspectives. Assessing the expression of molecular targets prior to definitive treatment is gaining importance in clinical practice. In this study, we investiga...

journal_title：Diagnostic pathology

authors： Lo RC,Leung CO,Chok KS,Ng IO

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:The occurrence of malignant lymphoma after delivery is an extremely rare event. Although several cases of Hodgkin lymphoma and B cell lymphoma and a few cases of peripheral T cell lymphoma (PTCL) after delivery have been reported, there are no report of autopsy cases of PTCL in the puerperal period. CASE PR...

journal_title：Diagnostic pathology

authors： Mizutani K,Yamada S,Guo X,Futatsuya C,Kumagai M,Shioya A,Aikawa A,Nakada S,Kurose N,Minato H,Nojima T

更新日期：2018-05-22 00:00:00

abstract：:Diagnostic surgical pathology or tissue–based diagnosis still remains the most reliable and specific diagnostic medical procedure. The development of whole slide scanners permits the creation of virtual slides and to work on so-called virtual microscopes. In addition to interactive work on virtual slides approaches ha...

journal_title：Diagnostic pathology

authors： Kayser K,Görtler J,Borkenfeld S,Kayser G

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Lung adenocarcinoma with EGFR activating mutations will inevitably acquire resistance to first generation TKIs. Acquired EGFR T790M mutation causes about 50% of these resistance cases. Droplet digital PCR (ddPCR) and cobas enables quantification of T790M mutation. Whether these methods can predict clinical r...

journal_title：Diagnostic pathology

authors： Li C,Jia R,Liu H,Zhang B,Wang C

更新日期：2018-08-13 00:00:00