Early retinol-binding protein levels are associated with growth changes in infants born to diabetic mothers.

Abstract:

BACKGROUND:Biochemical predictors of infants' growth changes are not available. OBJECTIVES:We tested whether retinol-binding protein (RBP), docosahexaenoic acid and insulin (I) measured within 72 h from birth are associated with growth changes in infants born to mothers with gestational diabetes mellitus (GDM). METHODS:Fifty-six children, 32 born to diabetic mothers treated with insulin (GDM-I) and 24 born to diabetic mothers treated with diet (GDM-D), were evaluated at 0, 1, 3, 6 and 12 months of life. RESULTS:At multivariable regression performed using generalized estimating equations, early RBP levels and maternal body mass index were associated to average weight changes and early RBP and insulin levels to average length changes, respectively. There was no difference between GDM-I and GDM-D infants. CONCLUSIONS:This exploratory study suggests that early RBP levels may be a predictor of growth changes.

journal_name

Pediatr Obes

journal_title

Pediatric obesity

authors

Francescato G,Agosti M,Bedogni G,Pastò E,Melzi d'Eril G,Barassi A,Risè P,Agostoni C

doi

10.1111/j.2047-6310.2012.00097.x

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

e86-9

issue

6

eissn

2047-6302

issn

2047-6310

journal_volume

7

pub_type

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