Abstract:
BACKGROUND:Primary prevention of overweight is to be preferred above secondary prevention, which has shown moderate effectiveness. OBJECTIVE:To develop and internally validate a dynamic prediction model to identify young children in the general population, applicable at every age between birth and age 6, at high risk of future overweight (age 8). METHODS:Data were used from the Prevention and Incidence of Asthma and Mite Allergy birth cohort, born in 1996 to 1997, in the Netherlands. Participants for whom data on the outcome overweight at age 8 and at least three body mass index SD scores (BMI SDS) at the age of ≥3 months and ≤6 years were available, were included (N = 2265). The outcome of the prediction model is overweight (yes/no) at age 8 (range 7.4-10.5 years), defined according to the sex- and age-specific BMI cut-offs of the International Obesity Task Force. RESULTS:After backward selection in a Generalized Estimating Equations analysis, the prediction model included the baseline predictors maternal BMI, paternal BMI, paternal education, birthweight, sex, ethnicity and indoor smoke exposure; and the longitudinal predictors BMI SDS, and the linear and quadratic terms of the growth curve describing a child's BMI SDS development over time, as well as the longitudinal predictors' interactions with age. The area under the curve of the model after internal validation was 0.845 and Nagelkerke R2 was 0.351. CONCLUSIONS:A dynamic prediction model for overweight was developed with a good predictive ability using easily obtainable predictor information. External validation is needed to confirm that the model has potential for use in practice.
journal_name
Pediatr Obesjournal_title
Pediatric obesityauthors
Welten M,Wijga AH,Hamoen M,Gehring U,Koppelman GH,Twisk JWR,Raat H,Heymans MW,de Kroon MLAdoi
10.1111/ijpo.12647subject
Has Abstractpub_date
2020-09-01 00:00:00pages
e12647issue
9eissn
2047-6302issn
2047-6310journal_volume
15pub_type
杂志文章abstract:BACKGROUND:In the USA, half of children are regularly cared for before or after school by someone other than a parent. OBJECTIVE:Describe the relationship between childcare arrangements and obesity among school-aged children. METHODS:Data are from the fifth-grade wave of the Early Childhood Longitudinal Study - Kinde...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12107
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Weight/length (W/L) indices are poor surrogates for adiposity in preterm infants born appropriate for gestational age (AGA) at birth, but whether the association subsequently improves is unknown. OBJECTIVE:To determine if W/L indices accurately reflect adiposity in premature infants born AGA in later infanc...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12744
更新日期:2020-11-03 00:00:00
abstract:BACKGROUND:There has been a growing amount of evidence indicating that excess visceral fat is associated with alterations in brain structure and function, including brain cortical thinning in adults. OBJECTIVES:This study aims to investigate the relationship between brain cortical thickness with obesity assessments, i...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12190
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Child obesity is a growing public health concern. Excess weight in childhood is known to be associated with a high risk of obesity and obesity-related comorbidities in adulthood. OBJECTIVES:This study quantifies lifetime excess costs of overweight and obese adults in Germany taking the history of obesity in...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.278
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:The relationships between the trajectories of weight gain from early childhood to adolescence and risk for metabolic disease are not well understood. OBJECTIVE:The objective of the study is to examine the relationships between weight gain from 2 to 14 years and metabolic risk factors at age 14 years in Paci...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12497
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Early life factors can programme future risk for cardiovascular disease. OBJECTIVES:We explored associations between adolescent adiponectin levels and concomitant metabolic alteration and also looked at the association between early life factors and adolescent adiponectin levels. METHODS:We studied a longi...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12212
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Increased consumption of sweetened beverages has previously been linked to the degree of childhood obesity. OBJECTIVE:The aim of the present study was to assess whether the intake of sweetened beverages, candy, snacks or fast food at baseline in a multidisciplinary childhood obesity treatment program was as...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12094
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Few studies have assessed how well body mass index (BMI), waist circumference (WC), or waist to height ratio (WtHR) perform in identifying cardio-metabolic risk among youth. OBJECTIVE:The objective of this study was to evaluate the utility of BMI and WC percentiles and WtHR to distinguish adolescents with a...
journal_title:Pediatric obesity
pub_type: 杂志文章,随机对照试验
doi:10.1111/ijpo.267
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Infants born small-for-gestational-age (SGA) who develop post-natal weight catch-up are at risk for insulin resistance, central adiposity and cardiovascular disease in later life, even in the absence of overweight. OBJECTIVE:In young (age 3-6 years) non-obese SGA children, we assessed arterial health (as ju...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12053
更新日期:2016-08-01 00:00:00
abstract:INTRODUCTION:To better inform the field of obesity medicine, we set out to describe the current use of pharmacotherapy meant to improve patient weight status among a group of clinicians connected through the Paediatric Obesity Weight Evaluation Registry (POWER), as well as reasons behind clinicians' use or non-use of t...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12701
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:In adults, depressive symptoms are positively associated with insulin resistance. OBJECTIVE:To determine whether an association exists between depressive symptoms and markers of insulin resistance in youth. METHODS:This study used a retrospective review of data from an obesity clinic. We evaluated the asso...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.237
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Population-specific accelerometer cut-points are required to accurately determine the accumulation of physical activity of various intensities. OBJECTIVES:A calibration study was conducted (i) to determine the cut-points for the ActiGraph GT3X+, non-dominant, wrist-mounted accelerometer in children aged 8-1...
journal_title:Pediatric obesity
pub_type: 杂志文章,多中心研究
doi:10.1111/ijpo.12033
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:We examined the association between gestational weight gain (GWG) and offspring obesity at age 36 months. METHODS:Mother-infant dyads (n = 609) were followed from a first study visit (mean [standard deviation]: 18.8 [2.7] weeks gestation) to 36 months postpartum. Total GWG over the entire pregnancy was defin...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.262
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Hepatic steatosis (HS) is currently the most prevalent hepatic disease in paediatric population and a major risk factor for type 2 diabetes and cardiovascular diseases. The proper identification of children with HS is therefore of great public health interest. OBJECTIVE:To develop a new prediction score usi...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12770
更新日期:2021-01-05 00:00:00
abstract:OBJECTIVE:This study aimed to examine physical activity (PA) patterns in children with autism spectrum disorder (ASD) as well as to address PA determinant factors by employing triaxial accelerometry. METHODS:In a school-based cross-sectional study of 80 children and adolescents with ASD (mean = 9.6, standard deviation...
journal_title:Pediatric obesity
pub_type: 杂志文章,多中心研究
doi:10.1111/j.2047-6310.2012.00101.x
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:There are no academic studies that characterize advertisements directed at children from the companies that signed the self-regulation. OBJECTIVE:The aim of this paper was to assess the extent and nature of food advertisements and the persuasive techniques used to market unhealthy food and beverages (UFB) t...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12144
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Non-alcoholic fatty liver disease (NAFLD), prediabetes and type 2 diabetes mellitus are known to be closely linked with obesity as early as during childhood. OBJECTIVES:The study aimed to determine the prevalence of prediabetes and T2DM in children with obesity with or without increased transaminases. METH...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12601
更新日期:2020-04-01 00:00:00
abstract::Gut microbes are active participants of host metabolism. At birth, child physiology is committed towards healthiness or sickness depending, in part, on maternal condition (i.e. lean vs obesity) and delivery. Finally, changes from breastfeeding to solid food also account to define gut microbiota ecology in adulthood. N...
journal_title:Pediatric obesity
pub_type: 杂志文章,评审
doi:10.1111/ijpo.12146
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Biochemical predictors of infants' growth changes are not available. OBJECTIVES:We tested whether retinol-binding protein (RBP), docosahexaenoic acid and insulin (I) measured within 72 h from birth are associated with growth changes in infants born to mothers with gestational diabetes mellitus (GDM). METHO...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/j.2047-6310.2012.00097.x
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Intestinal parasites, virus and bacterial infections are positively associated with obesity and adiposity in vitro and in animal models, but conclusive evidence of this relationship in humans is lacking. The aim of this cross-sectional study was to determine differences in adiposity between infected and non-...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12085
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVES:Growing evidence indicates that ambient (AAP: NO2 , PM2.5 and O3 ) and traffic-related air pollutants (TRAP) contribute to metabolic disease risk in adults; however, few studies have examined these relationships in children. METHODS:Metabolic profiling was performed in 429 overweight and obese African-Ameri...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12188
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Attention-deficit/hyperactivity disorder (ADHD) symptoms have been linked with eating behaviors and obesity adolescence and young adulthood. Yet, little is known about whether these associations occur during early childhood and few studies have examined these associations prospectively. OBJECTIVES:To assess...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12631
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:The incidence of type 2 diabetes mellitus (T2D) is increasing in youth, yet little is known about the underlying pathophysiology. Decreased insulin suppression of lipolysis and elevated non-esterified free fatty acid (NEFA) concentrations are known to be associated with insulin resistance and T2D in adults, ...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/j.2047-6310.2013.00189.x
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:The international (International Obesity Task Force; IOTF) body mass index (BMI) cut-offs are widely used to assess the prevalence of child overweight, obesity and thinness. Based on data from six countries fitted by the LMS method, they link BMI values at 18 years (16, 17, 18.5, 25 and 30 kg m(-2)) to child...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/j.2047-6310.2012.00064.x
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Dietary factors seem to influence telomere length. Moreover, associations between changes in adiposity indices and telomere length (TL) have been found in intervention studies. OBJECTIVE:We evaluated changes in two diet quality indices and their association with TL in children with abdominal obesity in a 12...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12661
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Drink personalization (featuring names on bottle labels) has been used by soft drink companies to make their drinks attractive to children, potentially increasing consumption. To date, no publically available research has evaluated the influence of personalization on children's drink choices. OBJECTIVES:To ...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12193
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Emerging adulthood is a critical time for excess weight gain. Risk can be masked if recommended overweight and obesity cut-points for Asians are not employed. OBJECTIVES:To determine the associations among sociodemographic factors and occurrence of overweight and obesity among normal weight 18-year olds. M...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12173
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:In adults, adherence to the Mediterranean diet has been inversely associated with cardiovascular risk, but the extent to which diet in pregnancy is associated with offspring adiposity is unclear. We aimed to investigate the association between adherence to Mediterranean diet in pregnancy and offspring cardio...
journal_title:Pediatric obesity
pub_type: 杂志文章
doi:10.1111/ijpo.12191
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Increases in portion size are thought by many to promote obesity in children. However, this relationship remains unclear. Here, we explore the extent to which a child's BMI is predicted both by parental beliefs about their child's ideal and maximum portion size and/or by the child's own beliefs. METHODS:Par...
journal_title:Pediatric obesity
pub_type: 杂志文章,随机对照试验
doi:10.1111/ijpo.12218
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:To conduct a systematic review of the literature for strategies designed to reduce attrition in managing paediatric obesity. METHODS:We searched Ovid Medline (1946 to May 6, 2020), Ovid Embase (1974 to May 6, 2020), EBSCO CINAHL (inception to May 6, 2020), Elsevier Scopus (inception to April 14, 2020), and P...
journal_title:Pediatric obesity
pub_type: 杂志文章,评审
doi:10.1111/ijpo.12733
更新日期:2020-09-22 00:00:00