Abstract:
BACKGROUND:Weight/length (W/L) indices are poor surrogates for adiposity in preterm infants born appropriate for gestational age (AGA) at birth, but whether the association subsequently improves is unknown. OBJECTIVE:To determine if W/L indices accurately reflect adiposity in premature infants born AGA in later infancy. METHODS:Associations between W/L indices and fat mass, fat mass index and percent body fat (%BF) obtained via air displacement plethysmography (ADP) were examined in 260 preterm infants (majority born AGA) at 28 to 63 weeks' postmenstrual age (PMA). Accuracy of W/L indices as indicators of adiposity was assessed by proportion of variance explained (R2 ) and root mean square error from linear regression of adiposity on W/L indices and proportion of infants misclassified by W/L indices. Accuracy was further compared in term vs preterm infants at term-equivalent age. The impact of early vs late preterm status on associations between W/L indices and %BF was also examined. RESULTS:BMI and W/L were most strongly associated with %BF but yielded poorly fitting models (maximum R2 = 0.35; 53% misclassification). A significant interaction of W/L indices and early vs late preterm status on %BF revealed that estimation of %BF differs by status. Accuracy of W/L indices was worse in preterm infants at term-equivalent age. CONCLUSIONS:W/L indices were not good indicators of adiposity in preterm infants from 28 to 63 weeks' PMA (born AGA) with all categories of W/L indices combined. Future research should examine whether results are similar in preterm infants born with disproportionate W/L or who experience disproportionate growth postnatally.
journal_name
Pediatr Obesjournal_title
Pediatric obesityauthors
Nagel E,Desjardins C,Earthman C,Ramel S,Demerath Edoi
10.1111/ijpo.12744subject
Has Abstractpub_date
2020-11-03 00:00:00pages
eijpo12744eissn
2047-6302issn
2047-6310pub_type
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journal_title:Pediatric obesity
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journal_title:Pediatric obesity
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journal_title:Pediatric obesity
pub_type: 杂志文章
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journal_title:Pediatric obesity
pub_type: 杂志文章
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journal_title:Pediatric obesity
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journal_title:Pediatric obesity
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journal_title:Pediatric obesity
pub_type: 杂志文章,随机对照试验
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journal_title:Pediatric obesity
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journal_title:Pediatric obesity
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journal_title:Pediatric obesity
pub_type: 杂志文章
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更新日期:2016-12-01 00:00:00
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journal_title:Pediatric obesity
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journal_title:Pediatric obesity
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更新日期:2016-06-01 00:00:00
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journal_title:Pediatric obesity
pub_type: 杂志文章,随机对照试验
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更新日期:2020-10-01 00:00:00
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journal_title:Pediatric obesity
pub_type: 杂志文章
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更新日期:2016-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2015-12-01 00:00:00
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journal_title:Pediatric obesity
pub_type: 杂志文章
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更新日期:2017-08-01 00:00:00
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journal_title:Pediatric obesity
pub_type: 杂志文章
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更新日期:2019-07-01 00:00:00
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journal_title:Pediatric obesity
pub_type: 杂志文章
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journal_title:Pediatric obesity
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journal_title:Pediatric obesity
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更新日期:2017-12-01 00:00:00
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更新日期:2020-04-01 00:00:00
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journal_title:Pediatric obesity
pub_type: 杂志文章,多中心研究
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更新日期:2013-04-01 00:00:00
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journal_title:Pediatric obesity
pub_type: 杂志文章
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更新日期:2020-06-01 00:00:00
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journal_title:Pediatric obesity
pub_type: 杂志文章,随机对照试验
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更新日期:2016-02-01 00:00:00
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journal_title:Pediatric obesity
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journal_title:Pediatric obesity
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更新日期:2020-03-01 00:00:00