Rebamipide prevents indomethacin-induced gastric mucosal lesion formation by inhibiting activation of neutrophils in rats.

abstract：BACKGROUND:Globus sensation is common, but its pathogenesis is not yet clear. AIMS:Our purpose was to investigate subjective perception of swallowing and esophageal motility by combined multichannel intraluminal impedance and manometry (MII-EM) for patients with globus sensation. METHODS:Combined MII-EM was performed...

journal_title：Digestive diseases and sciences

authors： Chen CL,Yi CH,Liu TT

更新日期：2013-04-01 00:00:00

abstract：:The aim of our prospective randomized study involving 100 patients was to investigate whether Doppler ultrasound can be used to select patients at risk for ulcer rebleeding. Ulcers in the Forrest group classified as having a visible vessel or a clot were treated prophylactically by injection with epinephrine solution....

journal_title：Digestive diseases and sciences

authors： Kohler B,Maier M,Benz C,Riemann JF

更新日期：1997-07-01 00:00:00

abstract：:Concentration and voltage dependence of Mg transport across the rat duodenum was measured in an Ussing chamber. Mucosa (m) to serosa (s) Mg flux exhibits a cellular fraction comparable to that found for Ca. Mg sm flux is purely diffusive and probably restricted to the paracellular pathway. At all concentrations betwee...

journal_title：Digestive diseases and sciences

authors： Karbach U,Schmitt A,Saner FH

更新日期：1991-11-01 00:00:00

abstract：:The major host defense mechanisms against bacterial overgrowth in the small bowel are the normal propulsive activity of the bowel itself and gastric acid secretion. Microbial interactions are a major factor in regulating the indigenous bacterial flora. Studies of the bacterial enzymes of the gut suggest that changes i...

journal_title：Digestive diseases and sciences

authors： Simon GL,Gorbach SL

更新日期：1986-09-01 00:00:00

abstract：:Campylobacter pyloridis has been associated with antral gastritis and duodenal ulcer. To study the pathogenetic role of these organisms in duodenal ulcer, endoscopic biopsies, two from the first part of duodenum, four from antrum, and four from body and fundus, were taken before and after four weeks of cimetidine trea...

journal_title：Digestive diseases and sciences

authors： Hui WM,Lam SK,Chau PY,Ho J,Lui I,Lai CL,Lok AS,Ng MM

更新日期：1987-11-01 00:00:00

abstract：:Autoimmune hepatitis has two major variant phenotypes in which the features of classical disease are co-mingled with those of primary biliary cirrhosis or primary sclerosing cholangitis. These overlap syndromes lack codified diagnostic criteria, established pathogenic mechanisms, and confident management strategies. T...

journal_title：Digestive diseases and sciences

authors： Czaja AJ

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Both 22- and 25-gauge needles are used for endoscopic ultrasound (EUS)-guided fine-needle aspiration (FNA) of lesions, yet limited data exist on whether either offers an advantage over the other in terms of specimen cellularity and quality. AIM:The aim of this study was to compare sample quality for 22- and...

journal_title：Digestive diseases and sciences

authors： Lee JH,Stewart J,Ross WA,Anandasabapathy S,Xiao L,Staerkel G

更新日期：2009-10-01 00:00:00

abstract：:The objective of this study was to investigate the effects of types of dialysis treatments on hepatitis C virus infection and the epidemiologic properties of hepatitis C virus (HCV) infection at three Baskent University hospitals, in Ankara, Adana, and Izmir, Turkey, in 655, 326, and 118 patients with end-stage renal ...

journal_title：Digestive diseases and sciences

authors： Selcuk H,Kanbay M,Korkmaz M,Gur G,Akcay A,Arslan H,Ozdemir N,Yilmaz U,Boyacioglu S

更新日期：2006-08-01 00:00:00

abstract：:On-demand therapy is effective for maintaining symptoms control in nonerosive gastroesophageal reflux disease (GERD). Our aim was to assess the clinical effectiveness of on-demand therapy with a proton pump inhibitor (PPI) in mild GERD (nonerosive and low-grade esophagitis), its impact on health-related quality of lif...

journal_title：Digestive diseases and sciences

authors： Ponce J,Argüello L,Bastida G,Ponce M,Ortiz V,Garrigues V

更新日期：2004-06-01 00:00:00

abstract：:A patient with multiple large hyperplastic (metaplastic) polyps of the colon is reported. Hundreds of polyps, some over 3 cm in size, were distributed uniformly throughout the large bowel. There was no evidence of polyps in the stomach or small intestine. The polyps, except for their large size, had the histologic fea...

journal_title：Digestive diseases and sciences

authors： Sumner HW,Wasserman NF,McClain CJ

更新日期：1981-01-01 00:00:00

abstract：:Canine and human exocrine pancreatic secretion into the duodenum during fasting is cyclical and related to intestinal motility. To characterize the composition of pure pancreatic juice during the cyclically recurring sequence of propagated motor events (interdigestive motor complex) and to establish whether pancreatic...

journal_title：Digestive diseases and sciences

authors： Keane FB,Dozois RR,Go VL,Dimagno EP

更新日期：1981-07-01 00:00:00

abstract：:Our objective was to investigate the expression of HMGA1 mRNA and protein in hepatocellular carcinoma (HCC) and the correlation between its expression and clinical pathological characteristics and prognosis. HMGA1 expression was determined at both the mRNA level and the protein level in 30 HCC tissues and their corres...

journal_title：Digestive diseases and sciences

authors： Chang ZG,Yang LY,Wang W,Peng JX,Huang GW,Tao YM,Ding X

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Prior to the consensus guideline conference in 2007, eosinophilic esophagitis (EoE) was uncommon dominated by the fibrostenotic phenotype, but over the past decade has become a common cause of dysphagia with more inflammatory phenotypes diagnosed. We assessed the impact of guideline definitions on t...

journal_title：Digestive diseases and sciences

authors： Lipka S,Boyce HW,Kumar A,Richter JE

更新日期：2015-06-01 00:00:00

abstract：:Autoimmune hepatitis (AIH) is rare in Asian countries compared to the West, and an exceptionally low prevalence was noted previously in Taiwan. Using the revised criteria of the IAIHG, 48 cases of AIH patients were diagnosed. All patients were consecutively diagnosed over a period of 5 years. Detailed medical historie...

journal_title：Digestive diseases and sciences

authors： Koay LB,Lin CY,Tsai SL,Lee C,Lin CN,Sheu MJ,Kuo HT,Sun CS

更新日期：2006-11-01 00:00:00

abstract：:Telomerase acitivity can be induced in human B lymphocytes by in vitro stimulation of their antigen receptors. To determine whether telomerase activity is induced in vivo, we analyzed telomerase activity in B lymphocytes from the mesenteric lymph nodes of patients with inflammatory bowel disease (IBD), whose lymph nod...

journal_title：Digestive diseases and sciences

authors： Takagi S,Kinouchi Y,Chida M,Hiwatashi N,Noguchi M,Takahashi S,Shimosegawa T

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Sorafenib, a drug that inhibits Raf serine/threonine kinases mediating cell proliferation and receptor tyrosine kinases involved in angiogenesis, is approved for treatment of advanced hepatocellular carcinoma. AIMS:To explore the efficacy and safety of sorafenib for treating advanced HCC, and to identify cl...

journal_title：Digestive diseases and sciences

authors： Xie B,Wang DH,Spechler SJ

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:New molecular biology-based methods of bacterial identification are expected to help elucidate the relationship between colorectal cancer (CRC) and intestinal microbiota. Although there is increasing evidence revealing the potential role of microbiota in CRC, it remains unclear whether microbial dysbiosis is...

journal_title：Digestive diseases and sciences

authors： Ohigashi S,Sudo K,Kobayashi D,Takahashi O,Takahashi T,Asahara T,Nomoto K,Onodera H

更新日期：2013-06-01 00:00:00

abstract：:This study was designed to determine the effect of a newly synthesized benzimidazole derivative NC-1300-B on H+, K+-ATPase (proton pump) in the hog gastric mucosa and on the basal gastric acid secretion and necrotizing agent-induced gastric lesions in rats. NC-1300-B inhibited the proton pump in a concentration-depend...

journal_title：Digestive diseases and sciences

authors： Okabe S,Akimoto Y,Yamasaki S,Nagai H

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Diagnosis of eosinophilic esophagitis (EoE) requires manual quantification of tissue eosinophils. Eosinophil peroxidase (EPX) is an eosinophil-specific, cytoplasmic granule protein released during degranulation. AIMS:The objective of this study was to evaluate image analysis of EPX immunohistochemistry as a...

journal_title：Digestive diseases and sciences

authors： Wright BL,Doyle AD,Shim KP,Pai RK,Barshow SM,Horsley-Silva JL,Luo H,Rank MA,Jacobsen EA,Katzka DA,Kita H,Dellon ES

更新日期：2020-04-04 00:00:00

abstract：:Small intestinal bacterial overgrowth (SIBO) has a high incidence in dogs and, as in humans, is difficult to diagnose. The aim of this study was to determine the diagnostic significance of serum unconjugated bile acid concentrations in dogs with bacterial overgrowth. Fasting sera were obtained from 23 dogs: 10 with cu...

journal_title：Digestive diseases and sciences

authors： Melgarejo T,Williams DA,O'Connell NC,Setchell KD

更新日期：2000-02-01 00:00:00

abstract：:We have studied pepsinogen synthesis and secretion in primary monolayer cultures of canine gastric chief cells. Monolayers were formed after approximately 48 hr. Pepsinogen synthesis was studied by adding 14C-labeled amino acids to the culture medium. Basal secretion of de novo synthesized pepsinogen after 4 hr was 4 ...

journal_title：Digestive diseases and sciences

authors： Defize J,Hunt RH

更新日期：1988-12-01 00:00:00

abstract：:Many physiological factors can alter gastric emptying, and the role of gastric emptying in functional dyspepsia is controversial. The aim of this study was to assess the effects of different factors (age, sex, the degree of dyspeptic and irritable bowel symptoms, lactase deficiency, smoking habits, the use of antiinfl...

journal_title：Digestive diseases and sciences

authors： Koskenpato J,Kairemo K,Korppi-Tommola T,Färkkilä M

更新日期：1998-06-01 00:00:00

abstract：INTRODUCTION:The C-31G polymorphism in the survivin promoter could de-repress the cell-cycle-dependent transcription of the human survivin gene, resulting in overexpression of survivin. This survivin mutation has only been studied on cervical carcinoma. However, no study has ever been conducted to evaluate the effect o...

journal_title：Digestive diseases and sciences

authors： Yang L,Zhu H,Zhou B,Gu H,Yan H,Tang N,Dong H,Sun Q,Cong R,Chen G,Wang B

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Wnt ligand binding initiates the interaction between Frizzled and Dvl proteins. However, the regulation of Frizzled-Dvl proteins interaction remains largely unknown. AIMS:The present study aims to elucidate the regulation of Frizzled-Dvl interaction by WDR34. METHODS:The protein levels of WDR34 in hepatoce...

journal_title：Digestive diseases and sciences

authors： Luo X,Liu Y,Ma S,Liu L,Xie R,Wang S

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Previous studies have shown vitamin D status to be associated with disease activity in patients with inflammatory bowel disease (IBD), but its influence on the clinical course of IBD has not been established. AIMS:We aimed to analyze whether the serum 25-hydroxyvitamin D3 [25(OH)D] status is associated with...

journal_title：Digestive diseases and sciences

authors： Ham NS,Hwang SW,Oh EH,Kim J,Lee HS,Park SH,Yang DH,Ye BD,Byeon JS,Myung SJ,Yang SK

更新日期：2020-03-26 00:00:00

abstract：:To examine the relationship between peptic ulcer and gastric cancer, we investigated 2529 patients with peptic ulcer diagnosed from 1963 to 1975. During the follow-up period of 9-23 years, we found 38 in whom gastric cancer developed or who died of gastric cancer. Included were nine in whom gastric cancer was detected...

journal_title：Digestive diseases and sciences

authors： Lee S,Iida M,Yao T,Shindo S,Okabe H,Fujishima M

更新日期：1990-06-01 00:00:00

abstract：:Our purpose was to observe the effects of sodium phosphate (NaP) colonoscopy preparation on serum electrolytes, phosphate, and calcium and to identify factors associated with any adverse effects. In an unselected group of 100 consecutive patients attending for out patient colonoscopy, 45% of patients had raised serum ...

journal_title：Digestive diseases and sciences

authors： Ainley EJ,Winwood PJ,Begley JP

更新日期：2005-07-01 00:00:00

abstract：:Verapamil, a type-1 calcium-channel blocker, given intraperitoneally, macroscopically protected the gastric mucosa of rats from 96% ethanol-induced lesions in a dose-dependent fashion. This effect was significant when verapamil at 10 or 20 mg/kg was given 1 hr before ethanol. Histopathologically, verapamil prevented t...

journal_title：Digestive diseases and sciences

authors： Gutiérrez-Cabano CA

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Topical pharyngeal anesthesia as an adjunct to intravenous sedation to facilitate gastroscopy has been widely acknowledged; however, its efficacy has not been established when it is used in patients under deep sedation with propofol. AIMS:To demonstrate the limited value of topical pharyngeal anesthesia in ...

journal_title：Digestive diseases and sciences

authors： Tsai HI,Tsai YF,Liou SC,Su MY,Lin CC,Chang CJ,Yu HP

更新日期：2012-10-01 00:00:00

abstract：:Alcoholic liver disease (ALD) is characterized by elevated serum IgA concentrations, the presence of circulating immune complexes containing IgA, and IgA deposits along sinusoids in the liver. When combined with the presupposed IgA-clearance function of the liver, a causal association between IgA abnormalities and the...

journal_title：Digestive diseases and sciences

authors： van de Wiel A,Valentijn RM,Schuurman HJ,Daha MR,Hené RJ,Kater L

更新日期：1988-06-01 00:00:00