Abstract:
:A capture IgE assay in EIA with diphtheria toxin and tetanus toxoid as model systems was developed and evaluated in relation to RIA in a DT booster study. The EIA and the RIA gave very similar results, although the EIA determined IgE over a wider range of concentrations, without interference by other subclasses. The comparison to the capture EIA indicated that the RIA gave more reliable results when a toxin as antigen. Weak correlations between local side effects and IgE responses and differences between vaccine groups were noted by RIA but not by EIA, which correlated better with the clinical findings.
journal_name
Vaccinejournal_title
Vaccineauthors
Wahren E,Bengtsson C,Björkstén B,Mark A,Granström Mdoi
10.1016/s0264-410x(97)00274-0subject
Has Abstractpub_date
1998-05-01 00:00:00pages
873-6issue
9-10eissn
0264-410Xissn
1873-2518pii
S0264-410X(97)00274-0journal_volume
16pub_type
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