Adjuvants influence the quantitative and qualitative immune response in BALB/c mice immunized with respiratory syncytial virus FG subunit vaccine.

abstract：OBJECTIVES:To assess the effectiveness and cost-effectiveness of routine childhood vaccination by new vaccines against rotavirus in France. METHODS:We constructed a Markov decision tree to compare two alternatives: "no vaccination" and "vaccination". A hypothetical birth cohort of 750,000 children was followed until 3...

journal_title：Vaccine

authors： Melliez H,Levybruhl D,Boelle PY,Dervaux B,Baron S,Yazdanpanah Y

更新日期：2008-01-30 00:00:00

abstract：:We tested whether pilus proteins of rabbit diarrhoeagenic Escherichia coli (RDEC-1), incorporated into biodegradable microspheres, could function as safe and effective oral immunogens in the rabbit diarrhoea model. The RDEC-1 adhesin, AF/R1, incorporated into poly(D,L-lactide-co-glycolide) microspheres, was administer...

journal_title：Vaccine

authors： McQueen CE,Boedeker EC,Reid R,Jarboe D,Wolf M,Le M,Brown WR

更新日期：1993-01-01 00:00:00

abstract：:The development of live attenuated vaccines, allowing for the safe and effective immunisation at mucosal surfaces, is a strategy of great interest for vaccinologists. The main advantage of this approach over conventional parenteral vaccines is the induction of strong mucosal immune responses, allowing targeting of the...

journal_title：Vaccine

authors： Viret JF,Dietrich G,Favre D

更新日期：2004-06-23 00:00:00

abstract：:Vaccination is the best available measure of limiting the impact of the next influenza pandemic. Ideally, a candidate pandemic influenza vaccine should be easy to administer and should elicit strong mucosal and systemic immune responses. Production of influenza subunit antigen in transient plant expression systems is ...

journal_title：Vaccine

authors： Madhun AS,Haaheim LR,Nøstbakken JK,Ebensen T,Chichester J,Yusibov V,Guzman CA,Cox RJ

更新日期：2011-07-12 00:00:00

abstract：:Crystallization of inulin with alum forms a fine (1-2 micron) suspension of electron-dense ovoids; the alum is embedded in inulin particles, which are then converted to the immune stimulant polymorphic form, gamma inulin. This very stable hybrid preparation is termed Algammulin. Preferred conditions for its preparatio...

journal_title：Vaccine

authors： Cooper PD,Steele EJ

更新日期：1991-05-01 00:00:00

abstract：:The full-length ecdysone receptor cDNA of Choristoneura fumiferana (CfEcR-B) was cloned into bacterial expression systems and the recombinant protein was expressed either with a His-tag (His-EcR-B) or glutathione-S-transferase (GST) fusion (GST-EcR-B). The His-EcR-B was expressed mostly as insoluble aggregates, while ...

journal_title：Vaccine

authors： Yang DH,Makhmoudova A,Arif BM,Feng Q,Retnakaran A,Palli SR,Krell PJ

更新日期：2006-04-12 00:00:00

abstract：:Severe diarrhea caused by rotavirus is a health problem worldwide, including Thailand. The World Health Organization has recommended incorporating rotavirus vaccination into national immunization programs. This policy has been implemented in several countries, but not in Thailand where the mortality rate is not high. ...

journal_title：Vaccine

authors： Muangchana C,Riewpaiboon A,Jiamsiri S,Thamapornpilas P,Warinsatian P

更新日期：2012-04-16 00:00:00

abstract：:In 1982, a two-dose programme of vaccination against measles, mumps and rubella (MMR) at the ages of 18 months and 12 years was introduced in Sweden. In 1992-3, the first group of children vaccinated at 18 months reached the age of 12, i.e. the time for a second dose. In connection with this 12-year vaccination, 376 c...

journal_title：Vaccine

authors： Böttiger M

更新日期：1995-12-01 00:00:00

abstract：:Porcine circovirus type-2b (PCV2b) is the primary global causative agent of porcine circovirus-associated disease (PCVAD). In this study, we first constructed a novel chimeric virus (PCV1-2b) with the PCV2b capsid gene cloned into the backbone of non-pathogenic PCV1. A pathogenicity study conducted in caesarean-derive...

journal_title：Vaccine

authors： Beach NM,Ramamoorthy S,Opriessnig T,Wu SQ,Meng XJ

更新日期：2010-12-16 00:00:00

abstract：:DNA-mediated immunizations have been used to raise neutralizing antibodies for measles virus. Single inoculations of plasmids expressing measles hemagglutinin or fusion glycoproteins raised neutralizing antibody in BALB/c mice. Plasmids expressing the hemagglutinin glycoprotein (both normal and secreted) raised neutra...

journal_title：Vaccine

authors： Yang K,Mustafa F,Valsamakis A,Santoro JC,Griffin DE,Robinson HL

更新日期：1997-06-01 00:00:00

abstract：:Carrier conjugation is commonly used to provide T-cell help for small, linear peptides containing antigen-specific B-cell epitopes. However, carrier conjugation is expensive, variable and often results in adverse side effects if the conjugate is administered repeatedly. To eliminate the need for carrier conjugation, w...

journal_title：Vaccine

authors： O'Hern PA,Liang ZG,Bambra CS,Goldberg E

更新日期：1997-11-01 00:00:00

abstract：:The challenges of the journey from target identification through development of a prophylactic quadrivalent human papillomavirus (HPV) vaccine have been met in Gardasil. Cervical cancer is the second leading cause of cancer-related death in women worldwide. Approximately 70% of cervical cancer is caused by infection w...

journal_title：Vaccine

authors： Bryan JT

更新日期：2007-04-20 00:00:00

abstract：:To evaluate the immunogenicity of 23-valent pneumococcal polysaccharide vaccine in 52 nursing homes residents aged > or = 60 years, IgG antibodies to serotypes 1, 5, 6B, and 8 were measured by ELISA and compared before, and 1 and 12 months following vaccination. A significant immunological response for all serotypes w...

journal_title：Vaccine

authors： Brandão AP,de Oliveira TC,de Cunto Brandileone MC,Gonçalves JE,Yara TI,Simonsen V

更新日期：2004-12-21 00:00:00

abstract：:A formalin-inactivated red sea bream iridovirus (RSIV) vaccine was prepared using the culture supernatant of a persistently infected Pagrus major fin cell line (PI-PMF) with IVS-1 strain (RSIV subtype II Meglaocytivirus). Rock bream (Oplegnathus fasciatus) were injected with a high-dose, ultracentrifuged megalocytivir...

journal_title：Vaccine

authors： Kwon WJ,Choi JC,Hong S,Kim YC,Jeong MG,Min JG,Jeong JB,Kim KI,Jeong HD

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND:Our understanding of the mother-to-child transfer of serotype-specific pneumococcal antibodies is limited in non-immunized, HIV-positive women. METHODS:We compared geometric mean antibody concentrations (GMCs), geometric mean transplacental cord:maternal ratios (GMRs) and proportions of samples with protect...

journal_title：Vaccine

authors： Gupta A,Mathad JS,Yang WT,Singh HK,Gupte N,Mave V,Bharadwaj R,Zaman K,Roy E,Bollinger RC,Bhosale R,Steinhoff MC

更新日期：2014-03-14 00:00:00

abstract：:Live cold-adapted recombinant bivalent vaccine of influenza type A was studied in a controlled field trial in 1982-1983 among nearly 30,000 children 3-15 years old. The bivalent vaccine consisted of recombinants 47/25/1 (H1N1) and 47/7/2 (H3N2) of wild-type viruses A/Brazil/11/78 (H1N1) and A/Bangkok/1/79 (H3N2) with ...

journal_title：Vaccine

authors： Alexandrova GI,Budilovsky GN,Koval TA,Polezhaev FI,Garmashova LM,Ghendon YuZ,Romanova YR,Smorodintsev AA

更新日期：1986-06-01 00:00:00

abstract：:SPf66 is the first chemically synthesised vaccine to elicit a partial protective immune response against malaria. The aluminium hydroxide (alum)-adsorbed SPf66 vaccine is weakly immunogenic and of poor to moderate efficacy in humans. To investigate the possibility of improving SPf66 vaccine immunogenicity, a delivery ...

journal_title：Vaccine

authors： Rosas JE,Hernández RM,Gascón AR,Igartua M,Guzman F,Patarroyo ME,Pedraz JL

更新日期：2001-08-14 00:00:00

abstract：:Travellers often present late for the third dose of hepatitis B vaccination and measuring anti-HBs serology is common practice to ensure that these individuals are protected. We assessed the adequacy of immune response in 86 healthy travellers who had their third dose of hepatitis B (HB) vaccine performed more than 1 ...

journal_title：Vaccine

authors： Jackson Y,Chappuis F,Mezger N,Kanappa K,Loutan L

更新日期：2007-04-30 00:00:00

abstract：:In order to evaluate the long-term immunity 2 and 3 years after booster vaccination against tick-borne encephalitis (TBE) following time intervals 3 years and longer since last TBE immunization, 195 (mean age 50.5+/-15.1 years) and 240 subjects (mean age 47.0+/-15.4 years), respectively, who had received a single boos...

journal_title：Vaccine

authors： Rendi-Wagner P,Paulke-Korinek M,Kundi M,Wiedermann U,Laaber B,Kollaritsch H

更新日期：2007-06-28 00:00:00

abstract：:Like any biotechnology innovation, the production of human vaccines in plants will succeed partly on its technical merits, and partly on the social acceptance of the new technology. The latter is harder to predict than the former, and may pose the most significant challenges to plant-derived vaccines' (PDVs) success. ...

journal_title：Vaccine

authors： Castle D,Dalgleish J

更新日期：2005-03-07 00:00:00

abstract：:Various peptide-based approaches to simultaneous induction of multiple cytotoxic T lymphocyte (CTL) responses were evaluated as part of ongoing efforts to develop immunotherapeutic vaccines for use in humans. To this end, HLA (human histocompatibility leukocyte antigen)-A2-restricted epitopes from several specific vir...

journal_title：Vaccine

authors： Oseroff C,Sette A,Wentworth P,Celis E,Maewal A,Dahlberg C,Fikes J,Kubo RT,Chesnut RW,Grey HM,Alexander J

更新日期：1998-05-01 00:00:00

abstract：:Numerous evidence demonstrate Type 1 diabetes (T1D) is due to a loss of immune tolerance to islet antigens, and CD8(+) T cells play an important role in the development of T1D in NOD mice. The novel coinhibitory receptor BTLA may have a regulatory role in maintaining peripheral tolerance, however, its role in autoimmu...

journal_title：Vaccine

authors： Li S,Zhang M,Xiang F,Zhao J,Jiang C,Zhu J

更新日期：2011-10-13 00:00:00

abstract：:DNA vaccination is particularly efficient for induction of cytotoxic T-lymphocyte (CTL) response. In our experiments, we used MHC(B) congenic chicken lines CB and CC (regressors and progressors of v-src-induced tumours, respectively) and a mutated, non-oncogenic v-src gene construct as the DNA vaccine. A high degree o...

journal_title：Vaccine

authors： Plachý JV,Hejnar JV,Trtková K,Trejbalová K,Svoboda J,Hála K

更新日期：2001-08-14 00:00:00

abstract：:Human papillomavirus type 16 (HPV16)-transformed mouse TC-1 cells are extensively used in the evaluation of efficacy of experimental vaccines against tumours induced by HPVs. As these cells strongly express MHC class I molecules and downregulation of MHC class I surface expression is one of the important mechanisms th...

journal_title：Vaccine

authors： Smahel M,Síma P,Ludvíková V,Marinov I,Pokorná D,Vonka V

更新日期：2003-03-07 00:00:00

abstract：:The conventional approach to vaccine development requires cultivation of the pathogenic microorganism and its dissection using biochemical, immunological, and microbiological methods in order to identify the components important for immunity. This method, while successful in many cases, failed to provide a solution fo...

journal_title：Vaccine

authors： Rappuoli R

更新日期：2001-03-21 00:00:00

abstract：:Analysis of the anti-haemagglutinin serum antibody proteome from six H1N1pdm09 influenza A vaccinated subjects demonstrated restricted IgG1 heavy chain species encoded by IGHV5-51 and IGHV3-7 gene families in 2 subjects and either IGHV5-51 or IGHV3-7 in 4 individuals. All subjects exhibited a dominant IGKV3-20 light c...

journal_title：Vaccine

authors： Adamson PJ,Al Kindi MA,Wang JJ,Colella AD,Chataway TK,Petrovsky N,Gordon TP,Gordon DL

更新日期：2017-10-09 00:00:00

abstract：:We compared the effects of yeast-treated human dendritic cells (DCs) with CD40L-matured human DCs for the induction of effector cells and the number and functionality of CD4(+)CD25(+)CD127(-)FoxP3(+) regulatory T cells (Tregs). DCs were treated with yeast or CD40L and cocultured with isolated autologous CD4(+) T cells...

journal_title：Vaccine

authors： Cereda V,Vergati M,Huen NY,di Bari MG,Jochems C,Intrivici C,Gulley JL,Apelian D,Schlom J,Tsang KY

更新日期：2011-07-12 00:00:00

abstract：BACKGROUND:To block transmission of measles, the China Ministry of Health endorsed the "2006-2012 National Measles Elimination Action Plan (NMEAP)" on November 11, 2006, while no published studies used mathematical models to assess the impact of this action. Also, the problem of residuals autocorrelation due to auto-co...

journal_title：Vaccine

authors： Xu L,Chen J,Zhan Z,Chen T,Liu W,Qian J,Ou C

更新日期：2020-06-09 00:00:00

abstract：BACKGROUND:While many clinicians encounter parents or adolescents who refuse HPV vaccine, little is known about the prevalence of hesitancy for HPV vaccine nationally or its association with vaccination. METHODS:In April 2019, we surveyed families with adolescents 11-17 years using a national online panel (Knowledge P...

journal_title：Vaccine

authors： Szilagyi PG,Albertin CS,Gurfinkel D,Saville AW,Vangala S,Rice JD,Helmkamp L,Zimet GD,Valderrama R,Breck A,Rand CM,Humiston SG,Kempe A

更新日期：2020-08-27 00:00:00

abstract：:Killed whole-cell preparations were used as bacterins against leptospirosis. As this type of protection is considered to be serogroup-specific, several serogroups were added to the usual vaccines, and the most pathogenic serovar was chosen for each group. Different leptospire extracts were evaluated for their protecti...

journal_title：Vaccine

authors： Sonrier C,Branger C,Michel V,Ruvoën-Clouet N,Ganière JP,André-Fontaine G

更新日期：2000-08-15 00:00:00