High immunogenicity of delayed third dose of hepatitis B vaccine in travellers.

Abstract:

:Travellers often present late for the third dose of hepatitis B vaccination and measuring anti-HBs serology is common practice to ensure that these individuals are protected. We assessed the adequacy of immune response in 86 healthy travellers who had their third dose of hepatitis B (HB) vaccine performed more than 1 year (median: 3.4 years; range: 1.1-10.5 years) after the second dose. Eighty-two travellers (95.3%) had evidence of sero-protection (anti-HBs titre >10 UI/L) including 16/17 (94.1%) travellers who had an interval of more than 5 years between second and third vaccine dose. We did not find any risk factor associated with insufficient response.

journal_name

Vaccine

journal_title

Vaccine

authors

Jackson Y,Chappuis F,Mezger N,Kanappa K,Loutan L

doi

10.1016/j.vaccine.2006.12.053

subject

Has Abstract

pub_date

2007-04-30 00:00:00

pages

3482-4

issue

17

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(06)01393-4

journal_volume

25

pub_type

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