Proteomic analysis of influenza haemagglutinin-specific antibodies following vaccination reveals convergent immunoglobulin variable region signatures.

abstract：:The immunogenicity of two meningococcal outer membrane vesicle (OMV) vaccines, namely the Norwegian wild-type OMV vaccine and the Dutch hexavalent PorA OMV vaccine, were examined in infant cynomolgus monkeys. For the first time, a wild-type- and a recombinant OMV vaccine were compared. Furthermore, the induction of me...

journal_title：Vaccine

authors： Rouppe van der Voort E,Schuller M,Holst J,de Vries P,van der Ley P,van den Dobbelsteen G,Poolman J

更新日期：2000-01-31 00:00:00

abstract：:Salmonella strains have great potential as live carriers of heterologous antigens to induce immunity against a variety of infectious diseases. However, the amount of heterologous antigen required to induce an adequate immune response may be toxic for the bacterium and result in cell death, overattenuation or loss of e...

journal_title：Vaccine

authors： Tijhaar EJ,Zheng-Xin Y,Karlas JA,Meyer TF,Stukart MJ,Osterhaus AD,Mooi FR

更新日期：1994-08-01 00:00:00

abstract：:Fluid cholera vaccine was examined for its stability at 4-8 degrees C, 20-25 degrees C and 37 degrees C with regard to the number of organisms present and the total nitrogen content. Ten batches of fluid cholera vaccine manufactured at the Central Research Institute, Kasauli, India were taken for the study. The number...

journal_title：Vaccine

authors： Gupta RK,Maheshwari SC,Sharma SB,Ahuja S,Saxena SN

更新日期：1984-12-01 00:00:00

abstract：:In chronic Hepatitis B Virus (HBV) infection the function of dendritic cells (DC), T- and B-cells is impaired. DC vaccination is an option to overcome this. DC pulsed in vitro with HBV sub viral particles (HBVsvp) and used to immunize mice can activate HBV directed humoral and cellular immune responses. In the present...

journal_title：Vaccine

authors： Farag MM,Tedjokusumo R,Flechtenmacher C,Asen T,Stremmel W,Müller M,Protzer U,Weigand K

更新日期：2012-09-14 00:00:00

abstract：BACKGROUND:The Advisory Committee on Immunization Practices (ACIP) routinely recommends three vaccines - influenza, hepatitis B, and pneumococcal vaccines - for End-Stage Renal Disease (ESRD) dialysis patients. METHODS:We sought to assess vaccination coverage among fee-for-service (FFS) Medicare beneficiaries with ESR...

journal_title：Vaccine

authors： Shen AK,Kelman JA,Warnock R,Zhang W,Brereton S,McKean S,Wernecke M,Chu S,Gellin BG

更新日期：2017-12-19 00:00:00

abstract：:The next-generation human anthrax vaccine developed by the United States Army Medical Research Institute of Infectious Diseases (USAMRIID) is based upon purified Bacillus anthracis recombinant protective antigen (rPA) adsorbed to aluminum hydroxide adjuvant (Alhydrogel). In addition to being safe, and effective, it is...

journal_title：Vaccine

authors： Ribot WJ,Powell BS,Ivins BE,Little SF,Johnson WM,Hoover TA,Norris SL,Adamovicz JJ,Friedlander AM,Andrews GP

更新日期：2006-04-24 00:00:00

abstract：:Oral poliovirus vaccine (OPV) is tested for safety by evaluation of neurovirulence in rhesus and cynomolgus macaques. After intraspinal or intrathalamic injection of varying doses of vaccine, monkeys are followed for 17-21 days, killed, and a histopathological evaluation is made of the severity of poliomyelitis lesion...

journal_title：Vaccine

authors： Nathanson N,Horn SD

更新日期：1992-01-01 00:00:00

abstract：:T lymphocytes play a central role in the generation of a protective immune response in many microbial infections. After immunization, dendritic cells take up microbial antigens and traffic to draining lymph nodes where they present processed antigens to naïve T cells. These naïve T cells are stimulated to proliferate ...

journal_title：Vaccine

authors： Esser MT,Marchese RD,Kierstead LS,Tussey LG,Wang F,Chirmule N,Washabaugh MW

更新日期：2003-01-17 00:00:00

abstract：:A dengue virus vaccine candidate, rDEN4Delta30, has been previously reported to be safe and immunogenic in humans, but a subset of vaccinees developed asymptomatic rash, elevation of liver enzymes and/or mild neutropenia. In the current study, mutations that had previously been shown to reduce replication of DEN4 viru...

journal_title：Vaccine

authors： Hanley KA,Manlucu LR,Manipon GG,Hanson CT,Whitehead SS,Murphy BR,Blaney JE Jr

更新日期：2004-09-03 00:00:00

abstract：:In order to establish a firm preventive measure for tick-borne encephalitis (TBE) in Japan, we evaluated the immune response of European vaccine against Japanese TBE virus strain (Oshima 5-10) for man and mouse. Furthermore, the efficacy of pre- and post-exposure protection by a polyclonal rabbit anti-TBE virus serum ...

journal_title：Vaccine

authors： Chiba N,Osada M,Komoro K,Mizutani T,Kariwa H,Takashima I

更新日期：1999-03-17 00:00:00

abstract：:The effectiveness of HPV vaccine against HSIL+ (pathologically diagnosed CIN2+) in the first cohort in Japan was investigated in 22,743 women aged 20 to 29 years (parts of national cervical cancer screening program of FY [fiscal year] 2015, the Japan Cancer Society). Vaccinated women had a statistically significant 69...

journal_title：Vaccine

authors： Konno R,Konishi H,Sauvaget C,Ohashi Y,Kakizoe T

更新日期：2018-12-18 00:00:00

abstract：:After introduction of a mono-component vaccine, containing only pertussis toxoid (PT), the incidence of pertussis was significantly higher in the Gothenburg area among children during the period October 1, 1997 until end of 2006 compared to the Rest of Sweden where a vaccine containing PT and two other pertussis antig...

journal_title：Vaccine

authors： Advani A,Gustafsson L,Ahrén C,Mooi FR,Hallander HO

更新日期：2011-04-18 00:00:00

abstract：:This study demonstrates that liposomes administered to the lower respiratory tract of mice have the capacity to stimulate secretory IgA (s-IgA) antibody production in the female urogenital system. Total respiratory tract immunization of mice with influenza virus subunit antigen simply mixed with negatively charged lip...

journal_title：Vaccine

authors： de Haan A,Renegar KB,Small PA Jr,Wilschut J

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Immunization with pneumococcal vaccines is an important prophylactic strategy for children with asplenia or splenic dysfunction, who are at high risk of bacterial infections (including S. pneumoniae). This study aimed to assess immunogenicity and safety of pneumococcal non-typeable Haemophilus influenzae pro...

journal_title：Vaccine

authors： Szenborn L,Osipova IV,Czajka H,Kharit SM,Jackowska T,François N,Habib MA,Borys D

更新日期：2017-09-25 00:00:00

abstract：:Understanding the mechanisms of generation and maintenance of immunological memory is crucial for rational vaccine design. A hypothesis known as relay hypothesis was earlier proposed which explains the maintenance of immunological memory through interaction of idiotypic and anti-idiotypic lymphocytes. In the present s...

journal_title：Vaccine

authors： Vani J,Nayak R,Shaila MS

更新日期：2007-06-21 00:00:00

abstract：:Mice inoculated intranasally (i.n.) with a recombinant strain of live Lactococcus lactis expressing tetanus toxin fragment C (TTFC), produced both serum and secretory antibodies to TTFC. Killed bacteria which had accumulated TTFC intracellularly in vitro also elicited protective serum antibody responses. There was no ...

journal_title：Vaccine

authors： Norton PM,Wells JM,Brown HW,Macpherson AM,Le Page RW

更新日期：1997-04-01 00:00:00

abstract：INTRODUCTION:The Global Vaccine Action Plan (GVAP), unanimously endorsed by the World Health Assembly in 2012, defined an ambitious strategy to improve immunization. At the end of the decade, significant progress has been made but four of the five GVAP goals are likely to be missed. This report describes a set of surve...

journal_title：Vaccine

authors： Hwang A,Veira C,Malvolti S,Cherian T,MacDonald N,Steffen C,Jones I,Hinman A,Mantel C

更新日期：2020-07-14 00:00:00

abstract：BACKGROUND:Currently, one lifetime booster of a 23-valent pneumococcal polysaccharide vaccine (PPV23) is recommended for those at highest risk of invasive pneumococcal disease (IPD) 3-5 years after initial vaccination. Due to a lack of evidence on multiple revaccinations, recommendations on repeat revaccination do not ...

journal_title：Vaccine

authors： Caya CA,Boikos C,Desai S,Quach C

更新日期：2015-03-10 00:00:00

abstract：:To evaluate primary care physicians' attitude towards implementation of rotavirus (RV) immunisation into the Swiss immunisation schedule, an eight-question internet-based questionnaire was sent to the 3799 subscribers of InfoVac, a nationwide web-based expert network on immunisation issues, which reaches >95% of paedi...

journal_title：Vaccine

authors： Agyeman P,Desgrandchamps D,Vaudaux B,Berger C,Diana A,Heininger U,Siegrist CA,Aebi C

更新日期：2009-07-30 00:00:00

abstract：INTRODUCTION:The burden of infection in communities determines the spread of rotavirus infection and disease in susceptible populations. This study reports rotavirus infection and disease in a community based birth cohort in Vellore. METHODS:Bimonthly surveillance and diarrheal stool were collected from 452 children e...

journal_title：Vaccine

authors： Paul A,Gladstone BP,Mukhopadhya I,Kang G

更新日期：2014-08-11 00:00:00

abstract：:A method was developed for cultivation of the strain Shigella flexneri 2a 77 with two attenuated markers. It ensures the preservation of the initial properties of the strain. The regimen for control of dissolved oxygen level was optimized. It was established that yeast extract is a necessary component of the nutritive...

journal_title：Vaccine

authors： Nenkov P,Bratoeva M,Vitanov T,Marinova S,Denchev V,Linde K

更新日期：1987-09-01 00:00:00

abstract：:Vaccination is an effective strategy to prevent pneumococcal diseases. Currently, licensed vaccines include the pneumococcal polysaccharide vaccine (PPSV) and the pneumococcal conjugate vaccine (PCV), which target some of the most common of the 94 serotypes of S. pneumoniae based on their capsular composition. However...

journal_title：Vaccine

authors： Nagai K,Domon H,Maekawa T,Hiyoshi T,Tamura H,Yonezawa D,Habuka R,Saitoh A,Terao Y

更新日期：2019-01-03 00:00:00

abstract：:Respiratory syncytial virus F-protein (RSV-F) is poorly expressed from DNA expression plasmids containing the wild type RSV-F open reading frame. By codon optimization, premature polyadenylation signals were deleted and a striking enhancement of RSV-F expression levels was achieved. Therefore, the immunogenicity and e...

journal_title：Vaccine

authors： Ternette N,Tippler B,Uberla K,Grunwald T

更新日期：2007-10-10 00:00:00

abstract：BACKGROUND:Invasive pneumococcal disease and respiratory tract infections are both frequent and severe in patients with systemic lupus erythematosus (SLE). This study aimed to compare the immunological efficacy and safety of pneumococcal vaccination with the 23-valent polysaccharide (PPS) vaccine alone to a sequential ...

journal_title：Vaccine

authors： Grabar S,Groh M,Bahuaud M,Le Guern V,Costedoat-Chalumeau N,Mathian A,Hanslik T,Guillevin L,Batteux F,Launay O,VACCILUP study group.

更新日期：2017-09-05 00:00:00

abstract：BACKGROUND:During the past decade, in the United States, an increasing number of hepatitis B outbreaks have been reported in assisted living facilities (ALFs) as a result of breaches in infection control practices. We evaluated the seroprotection rates conferred by hepatitis B vaccine among older adults during a respon...

journal_title：Vaccine

authors： Tohme RA,Awosika-Olumo D,Nielsen C,Khuwaja S,Scott J,Xing J,Drobeniuc J,Hu DJ,Turner C,Wafeeg T,Sharapov U,Spradling PR

更新日期：2011-11-21 00:00:00

abstract：:Hepatitis B infections are responsible for more than 300 thousand deaths per year in the Western Pacific Region. Because of this high burden, the countries and areas of the Region established a goal of reducing hepatitis B chronic infection prevalence among children to less than 1% by 2017. This study was conducted to...

journal_title：Vaccine

authors： Wiesen E,Diorditsa S,Li X

更新日期：2016-05-27 00:00:00

abstract：:The spike peplomer S1 subunit sequence from avian infectious bronchitis virus (IBV) Vic S strain was expressed in a plasmid under the control of the fowl adenovirus (FAV) major late promoter (MLP). Two recombinants were constructed in FAV serotype 8 (FAV 8) by inserting the expression cassette between the SnaBI and Xb...

journal_title：Vaccine

authors： Johnson MA,Pooley C,Ignjatovic J,Tyack SG

更新日期：2003-06-20 00:00:00

abstract：:Haemophilus parasuis (H. parasuis), the causative agent of swine polyserositis, polyarthritis, and meningitis, is one of the most important bacterial diseases of pigs worldwide. Little vaccines currently exist that have a significant effect on infections with all pathogenic serovars of H. parasuis. H. parasuis putativ...

journal_title：Vaccine

authors： Fu S,Zhang M,Xu J,Ou J,Wang Y,Liu H,Liu J,Chen H,Bei W

更新日期：2013-01-02 00:00:00

abstract：:Safe RSV vaccine development has challenged the medical community since a formalin-killed RSV vaccine caused disease exacerbation in the 1960s. Disease was replicated using the bovine RSV system in one of two studies. The studies differed in viral protein dose and length of time between vaccination and infection. Dise...

journal_title：Vaccine

authors： Kalina WV,Woolums AR,Berghaus RD,Gershwin LJ

更新日期：2004-03-29 00:00:00

abstract：:Obesity is a risk factor for complicated influenza A/H1N1 disease and poor vaccine immunogenicity. Leptin, an adipocyte-derived hormone/cytokine, has many immune regulatory functions and therefore could explain susceptibility to infections and poor vaccine outcomes. We recruited 159 healthy adults (50-74 years old) wh...

journal_title：Vaccine

authors： Ovsyannikova IG,White SJ,Larrabee BR,Grill DE,Jacobson RM,Poland GA

更新日期：2014-02-07 00:00:00