Effectiveness of HPV vaccination against high grade cervical lesions in Japan.

abstract：:Plasmodium falciparum Pfs25 antigen, expressed on the surface of zygotes and ookinetes, is one of the leading targets for the development of a malaria transmission-blocking vaccine (TBV). Our laboratory has been evaluating DNA plasmid based Pfs25 vaccine in mice and non-human primates. Previously, we established that ...

journal_title：Vaccine

authors： Kumar R,Nyakundi R,Kariuki T,Ozwara H,Nyamongo O,Mlambo G,Ellefsen B,Hannaman D,Kumar N

更新日期：2013-06-28 00:00:00

abstract：:At the Netherlands Vaccine Institute (NVI) a vaccine against Neisseria meningitidis serogroup B organisms based on different porA subtypes contained in outer membrane vesicles (OMVs) is in advanced stage of development and will be evaluated in clinical trial studies in the near future. In order to meet the expected de...

journal_title：Vaccine

authors： Baart GJ,de Jong G,Philippi M,van't Riet K,van der Pol LA,Beuvery EC,Tramper J,Martens DE

更新日期：2007-08-21 00:00:00

abstract：:The interactions of Plasmodium falciparum infected erythrocytes parasitized red blood cells (pRBC) with endothelial receptors and erythrocytes are mediated by multiple Duffy-binding like (DBL) and cysteine-rich interdomain region (CIDR) domains harboured in the Plasmodium falciparum erythrocyte membrane protein 1 (PfE...

journal_title：Vaccine

authors： Ahuja S,Pettersson F,Moll K,Jonsson C,Wahlgren M,Chen Q

更新日期：2006-08-28 00:00:00

abstract：BACKGROUND:Invasive pneumococcal disease and respiratory tract infections are both frequent and severe in patients with systemic lupus erythematosus (SLE). This study aimed to compare the immunological efficacy and safety of pneumococcal vaccination with the 23-valent polysaccharide (PPS) vaccine alone to a sequential ...

journal_title：Vaccine

authors： Grabar S,Groh M,Bahuaud M,Le Guern V,Costedoat-Chalumeau N,Mathian A,Hanslik T,Guillevin L,Batteux F,Launay O,VACCILUP study group.

更新日期：2017-09-05 00:00:00

abstract：BACKGROUND:China is the most populous country in the world, with an annual birth cohort of approximately 16 million, requiring an average of 500 million vaccine doses administered annually. In China, over 30 domestic and less than 10 overseas vaccine manufacturers supply over 60 licensed vaccine products, representing ...

journal_title：Vaccine

authors： Guo B,Page A,Wang H,Taylor R,McIntyre P

更新日期：2013-01-11 00:00:00

abstract：:Anthrax vaccine adsorbed (AVA), an effective countermeasure against anthrax, is administered as six subcutaneous (SQ) doses over 18 months. To optimize the vaccination schedule and route of administration, we performed a prospective pilot study comparing the use of fewer AVA doses administered intramuscularly (IM) or ...

journal_title：Vaccine

authors： Pittman PR,Kim-Ahn G,Pifat DY,Coonan K,Gibbs P,Little S,Pace-Templeton JG,Myers R,Parker GW,Friedlander AM

更新日期：2002-01-31 00:00:00

abstract：:Japanese encephalitis is a major cause of encephalitis in Asia. Cases occur largely in rural areas of the South and East Asian region resulting in significant morbidity and mortality. Multiple vaccines exist to control Japanese encephalitis, but all suffer from problems. Envelope protein domain III of Japanese encepha...

journal_title：Vaccine

authors： Verma SK,Kumar S,Gupta N,Vedi S,Bhattacharya SM,Lakshmana Rao PV

更新日期：2009-11-16 00:00:00

abstract：:A National Immunization Technical Advisory Group (NITAG) is an expert advisory committee that provides evidence-based recommendations to the Ministry of Health (MoH) to guide immunization programs and policies. The World Health Organization (WHO), the Initiative for Supporting National Independent Immunization and Vac...

journal_title：Vaccine

authors： Blau J,Sadr-Azodi N,Clementz M,Abeysinghe N,Cakmak N,Duclos P,Janusz C,Jauregui B,Mihigo R,Mosina L,Takashima Y,Senouci K

更新日期：2013-05-28 00:00:00

abstract：:Both seasonal and pandemic influenza cause considerable morbidity and mortality globally. In addition, the ongoing threat of new, unpredictable influenza pandemics from emerging variant strains cannot be underestimated. Recently bioCSL (previously known as CSL Biotherapies) sponsored a symposium 'New Wisdom to Defy an...

journal_title：Vaccine

authors： Poland GA,Fleming DM,Treanor JJ,Maraskovsky E,Luke TC,Ball EM,Poland CM

更新日期：2013-04-17 00:00:00

abstract：:Susceptible dairy cattle were immunized with attenuated, live calf-derived, in vitro-cultured or biologically cloned Babesia bovis, with non-viable exoantigens, or with recombinant rhoptry-associated protein 1 (rRAP1). Antibody response assessed by the indirect fluorescent assay (IFA) and by the growth inhibition acti...

journal_title：Vaccine

authors： Fish L,Leibovich B,Krigel Y,McElwain T,Shkap V

更新日期：2008-12-19 00:00:00

abstract：:Assuming that the level of Bacille Calmette Guerin (BCG) coverage gives a measure of access to immunisation services, it is possible to derive what fraction of infants are not immunised against measles due to under-utilisation of existing services (rather than unavailability of services). According to the most recent ...

journal_title：Vaccine

authors： Edmunds WJ,Gay NJ,Henao Restrepo AM,Olivé JM,Bele O

更新日期：2001-10-12 00:00:00

abstract：:The great clinical and economical impact of Toxoplasma gondii infections makes the development of an effective vaccine for controlling toxoplasmosis an extremely important aim. In the presented study, we evaluate the protective and immunogenic properties of three recombinant subunit vaccines composed of rROP2+rGRA4+rS...

journal_title：Vaccine

authors： Dziadek B,Gatkowska J,Brzostek A,Dziadek J,Dzitko K,Grzybowski M,Dlugonska H

更新日期：2011-01-17 00:00:00

abstract：BACKGROUND:Protein-polysaccharide conjugate vaccines such as Haemophilus influenzae type b (Hib), meningococcal, and pneumococcal vaccine, induce immunological memory and longer lasting protection than plain polysaccharide vaccines. The most common proteins used as carriers are tetanus toxoid (TT) and cross reacting ma...

journal_title：Vaccine

authors： Voysey M,Sadarangani M,Clutterbuck E,Bolgiano B,Pollard AJ

更新日期：2016-07-25 00:00:00

abstract：:This study investigates the safety, immunogenicity and efficacy of different pox-vector vaccines expressing the haemagglutinin of a highly pathogenic (HP) H5N1 avian influenza virus (AIV) (A/chicken/Indonesia/7/03) in pigs. Pigs were vaccinated twice, with a 4-week interval, with a fowlpox (TROVAC), a canarypox (ALVAC...

journal_title：Vaccine

authors： Kyriakis CS,De Vleeschauwer A,Barbé F,Bublot M,Van Reeth K

更新日期：2009-04-06 00:00:00

abstract：INTRODUCTION:Despite the enormous benefits of childhood and maternal immunisation to individual and population health, the uptake of maternal vaccines during pregnancy remains suboptimal. Midwives are a trusted information source for parents and play an important role in the provision of immunisation information. Under...

journal_title：Vaccine

authors： Frawley JE,McKenzie K,Sinclair L,Cummins A,Wardle J,Hall H

更新日期：2020-01-10 00:00:00

abstract：:The continued use of oral polio vaccine (OPV) poses a threat to polio virus eradication. Stopping all polio vaccination in the post-certification era is no longer considered to be a practical option. Policy makers agree that OPV use must stop immediately after certification. Therefore, the pragmatic alternative is for...

journal_title：Vaccine

authors： Khan MM

更新日期：2008-04-07 00:00:00

abstract：:Heat shock proteins (HSP) are highly conserved molecules that play important roles in protein folding, assembly of protein complexes and translocation of proteins across cellular compartments, as well as in several immunological processes. In this study, we first immunized susceptible BALB/c and resistant C57BL/6 mice...

journal_title：Vaccine

authors： Rafati S,Gholami E,Hassani N,Ghaemimanesh F,Taslimi Y,Taheri T,Soong L

更新日期：2007-05-22 00:00:00

abstract：:Malaria caused by Plasmodium falciparum continues to threaten millions of people living in the tropical parts of the world. A vaccine that confers sterile and life-long protection remains elusive despite more than 30years of effort and resources invested in solving this problem. Antibodies to a malaria vaccine candida...

journal_title：Vaccine

authors： Genito CJ,Beck Z,Phares TW,Kalle F,Limbach KJ,Stefaniak ME,Patterson NB,Bergmann-Leitner ES,Waters NC,Matyas GR,Alving CR,Dutta S

更新日期：2017-07-05 00:00:00

abstract：:Oral and inactivated poliomyelitis vaccines (OPV and IPV), were given to 160 children two months old, in a low income population at Rio de Janeiro. The vaccination was repeated 2 and 4 months later, always in association with diphtheria, tetanus and pertussis (DPT) vaccine. Blood specimens were collected before vaccin...

journal_title：Vaccine

authors： Schatzmayr HG,Maurice Y,Fujita M,de Fillipis AM

更新日期：1986-06-01 00:00:00

abstract：:Salmonella strains have great potential as live carriers of heterologous antigens to induce immunity against a variety of infectious diseases. However, the amount of heterologous antigen required to induce an adequate immune response may be toxic for the bacterium and result in cell death, overattenuation or loss of e...

journal_title：Vaccine

authors： Tijhaar EJ,Zheng-Xin Y,Karlas JA,Meyer TF,Stukart MJ,Osterhaus AD,Mooi FR

更新日期：1994-08-01 00:00:00

abstract：:This study compared responses of bison calves to 10(10)CFU of Brucella abortus strain RB51 (SRB51) delivered by parenteral or ballistic methods. Two types of biobullet payloads were evaluated; compacted SRB51 pellets or SRB51 encapsulated in photopolymerized poly(ethylene glycol) hydrogels. Bison were vaccinated with ...

journal_title：Vaccine

authors： Olsen SC,Christie RJ,Grainger DW,Stoffregen WS

更新日期：2006-02-27 00:00:00

abstract：:Thirty-two rhesus monkeys were used to evaluate the dose response of a recombinant HEV vaccine, and the efficacy of the vaccine based on the ORF2 protein of the Pakistani strain for pre- and post-exposure vaccination against intravenous challenge with homologous or heterologous virus was examined. Post-exposure vaccin...

journal_title：Vaccine

authors： Tsarev SA,Tsareva TS,Emerson SU,Govindarajan S,Shapiro M,Gerin JL,Purcell RH

更新日期：1997-12-01 00:00:00

abstract：:Patients with malignancies are considered to be at increased risk of acquiring influenza. Because of higher complication and case fatality rates, preventive measures such as vaccination are of great interest. The objective of this study was to assess the acceptability, tolerability and immunogenicity of an adjuvant-fr...

journal_title：Vaccine

authors： Lagler H,Tobudic S,Ramharter M,Elandt K,Sperr WR,Redlberger-Fritz M,Popow-Kraupp T,Jäger U,Zielinski CC,Burgmann H

更新日期：2012-11-06 00:00:00

abstract：:Dengue disease is a global challenge for healthcare systems particularly during outbreaks, and millions of dollars are spent every year for vector control. An efficient and safe vaccine that is cost-effective could resolve the burden that dengue virus imposes on affected countries. We describe here the immunogenicity ...

journal_title：Vaccine

authors： Zuest R,Valdes I,Skibinski D,Lin Y,Toh YX,Chan K,Hermida L,Connolly J,Guillen G,Fink K

更新日期：2015-03-17 00:00:00

abstract：:Bovine tuberculosis (bTB) is increasing in incidence in the UK. Effective control strategies could involve vaccination; BCG, either alone or in prime-boost strategies, remains the most effective vaccine against bovine tuberculosis. However, BCG vaccination of cattle would require development of diagnostic tests able t...

journal_title：Vaccine

authors： Sopp P,Coad M,Hewinson G,Howard CJ,Cheallaigh CN,Keane J,Harris J,Hope JC

更新日期：2008-10-09 00:00:00

abstract：:Brucellosis is one of the most prevalent zoonotic diseases of worldwide distribution caused by the infection of genus Brucella. Live attenuated vaccines such as B. abortus S19, B. abortus RB51 and B. melitensis Rev1 are found most effective against brucellosis infection in animals, contriving a number of serious side ...

journal_title：Vaccine

authors： Vrushabhendrappa,Singh AK,Balakrishna K,Sripathy MH,Batra HV

更新日期：2014-09-29 00:00:00

abstract：:We examined the immunogenicity and protective efficacy of a combined DNA vaccine that included six genes encoding immunodominant antigens from Mycobacterium tuberculosis and Brucella abortus. The IL-12 adjuvant system was used for immunization in combination with the combined DNA vaccine (DNA-IL-12(+)). Mice immunized...

journal_title：Vaccine

authors： Yu DH,Li M,Hu XD,Cai H

更新日期：2007-09-17 00:00:00

abstract：:Cholera is a potentially lethal diarrhea disease caused by the gram-negative bacterium Vibrio cholerae. The need for an effective cholera vaccine is clearly indicated but the challenges of eliciting both systemic and mucosal immune responses remains a significant challenge. In the current report, we discovered that a ...

journal_title：Vaccine

authors： Xu G,Wang S,Zhuang L,Hackett A,Gu L,Zhang L,Zhang C,Wang H,Huang Z,Lu S

更新日期：2009-06-12 00:00:00

abstract：:Synthetic oligonucleotides (ODNs) containing immunostimulatory CpG motifs (CpG) are a new class of adjuvants suitable for the development of recombinant vaccines. Here we describe that endogenous interferon (IFN) was critical for the adjuvant activity of CpG ODN as genetically deficient mice developed significantly lo...

journal_title：Vaccine

authors： Rosa DS,Bastos KR,Bargieri DY,Tzelepis F,Nomizo A,Russo M,Soares IS,Rodrigues MM

更新日期：2007-08-10 00:00:00

abstract：:Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of Johne's Disease, a chronic granulomatous enteritis of ruminants. Recently, an association of MAP bacilli with Crohn's disease in humans has been proposed. Due to genetic similarities and serological cross-reactivity of the M. avium complex wit...

journal_title：Vaccine

authors： Sechi LA,Ahmed N,Felis GE,Duprè I,Cannas S,Fadda G,Bua A,Zanetti S

更新日期：2006-01-16 00:00:00