Differential efficacy of vaccinia virus envelope proteins administered by DNA immunisation in protection of BALB/c mice from a lethal intranasal poxvirus challenge.

abstract：:The amounts of pertussis toxin (PT), filamentous haemagglutinin (FHA), 69 kDa outer membrane protein (69 kDa OMP) and agglutinogens (AGG) 2 and 3 in extracts from the Danish whole-cell pertussis vaccine were studied in quantitative capture ELISA. With the exception of PT, the most effective extraction of these antigen...

journal_title：Vaccine

authors： Ibsen PH,Petersen JW,Heron I

更新日期：1993-01-01 00:00:00

abstract：:To test several vaccines for Chlamydia trachomatis we vaccinated BALB/c and C3H/HeN female mice with a purified preparation of the native mouse pneumonitis (MoPn) major outer membrane protein (MOMP). The MOMP was formulated with anyone of three different adjuvants MF59, LT-K63 or LT-R72. As a negative control the anim...

journal_title：Vaccine

authors： Pal S,Peterson EM,Rappuoli R,Ratti G,de la Maza LM

更新日期：2006-02-06 00:00:00

abstract：:The neutralising antibody response after the yellow fever vaccine (YF-17D) skin test was measured in 7 egg allergic persons in whom further vaccination was abandoned because of a strong local urticarial reaction to the YF-17D vaccine test dose. We found that this test dose of 0.1mL of YF-17D vaccine was sufficient to ...

journal_title：Vaccine

authors： Roukens AH,Vossen AC,van Dissel JT,Visser LG

更新日期：2009-04-21 00:00:00

abstract：BACKGROUND:In 2009, Thailand recommended pregnant women be prioritized for influenza vaccination. Vaccine uptake among Thai pregnant women is lower than other high-risk groups. METHODS:During December 2012-April 2013, we conducted a cross-sectional survey of a convenience sample of Thai pregnant women aged ≥ 15 years ...

journal_title：Vaccine

authors： Ditsungnoen D,Greenbaum A,Praphasiri P,Dawood FS,Thompson MG,Yoocharoen P,Lindblade KA,Olsen SJ,Muangchana C

更新日期：2016-04-19 00:00:00

abstract：:Since preexisting immunity and enhanced infection rates in a clinical trial of an HIV vaccine have raised some concerns on adenovirus (Ad) serotype 5-based vaccines, we evaluated the subgroup D adenovirus serotype Ad19a for its suitability as novel viral vector vaccine against mucosal infections. In BALB/c mice, we co...

journal_title：Vaccine

authors： Lapuente D,Ruzsics Z,Thirion C,Tenbusch M

更新日期：2018-05-03 00:00:00

abstract：BACKGROUND:Gram-negative bacteria (GNB) are a leading cause of nosocomial infection and sepsis. Increasing multi-antibiotic resistance has left clinicians with fewer therapeutic options. Antibodies to GNB lipopolysaccharide (LPS, or endotoxin) have reduced morbidity and mortality as a result of infection and are not su...

journal_title：Vaccine

authors： Cross AS,Greenberg N,Billington M,Zhang L,DeFilippi C,May RC,Bajwa KK

更新日期：2015-11-27 00:00:00

abstract：:Adjuvants are substances that enhance adaptive immune response to antigen. Development of a safe and effective immunostimulant adjuvant is essential for the efficacy of a vaccine to protect against infectious pathogens. Purple non-sulfur photosynthetic bacteria exhibited nontoxic natural lipid A variants that are dist...

journal_title：Vaccine

authors： Masoud H

更新日期：2019-06-06 00:00:00

abstract：BACKGROUND:23-Valent pneumococcal polysaccharide vaccine, trade name Pneumovax(®)23 (PPSV23), has been used for decades in the Unites States and has an extensive clinical record. However, limited post-licensure safety assessment has been conducted. OBJECTIVE:To analyze reports submitted to the Vaccine Adverse Event Re...

journal_title：Vaccine

authors： Miller ER,Moro PL,Cano M,Lewis P,Bryant-Genevier M,Shimabukuro TT

更新日期：2016-05-27 00:00:00

abstract：:A DNA vaccine codifying the mycobacterial hsp65 can prevent infection with Mycobacterium tuberculosis in a prophylactic setting and also therapeutically reduce the number of bacteria in infected mice. The protective mechanism is thought to be related to Th1-mediated events that result in bacterial killing. To determin...

journal_title：Vaccine

authors： Lima KM,dos Santos SA,Santos RR,Brandão IT,Rodrigues JM Jr,Silva CL

更新日期：2003-12-08 00:00:00

abstract：:Hepatitis A and B are common infections worldwide and their severity is related to the individual's age upon initial infection. Furthermore, when hepatitis B infection occurs in infants, the risk of becoming a chronic carrier is 90%. For hepatitis A, the lower incidence of disease arising from an improvement in living...

journal_title：Vaccine

authors： Van Damme P,Van der Wielen M

更新日期：2001-03-21 00:00:00

abstract：BACKGROUND:Vaccination coverage in Bosnia and Herzegovina has been declining over recent years. A World Health Organization Tailoring Immunization Programmes (TIP) project is underway to gain insights into the underlying reasons for this, to develop tailored interventions. As part of TIP, this study aimed to investigat...

journal_title：Vaccine

authors： Musa S,Skrijelj V,Kulo A,Habersaat KB,Smjecanin M,Primorac E,Becirovic D,Jackson C

更新日期：2020-02-18 00:00:00

abstract：:The use of vaccinia virus in recombinant systems may result in the occurrence of complications observed following smallpox vaccination. The results are presented of a large survey carried out in the USSR between 1968 and 1979. High complication rates are reported, particularly in older primary vaccinees; for example, ...

journal_title：Vaccine

authors： Gurvich EB

更新日期：1992-01-01 00:00:00

abstract：:DNA isolates from a number of established cell lines have been tested for their transforming capacity in the NIH3T3 transformation assay. It has been found that this assay can be used to quantify the amount of transforming DNA at a submicrogram to milligram level. This assay system has been applied to validate the red...

journal_title：Vaccine

authors： van Meel FC,Steenbakkers PG,Bos E

更新日期：1985-12-01 00:00:00

abstract：:The trivalent inactivated vaccine (TIV) is used to prevent seasonal influenza virus infection in humans, however, the immunogenicity of this vaccine may be influenced by the priming effect of previous influenza vaccinations or exposure to antigenically related influenza viruses. The current study examines the immunoge...

journal_title：Vaccine

authors： Wang S,Parker C,Taaffe J,Solórzano A,García-Sastre A,Lu S

更新日期：2008-07-04 00:00:00

abstract：INTRODUCTION:Rotavirus infection mainly affects children under 5 years of age and causes 453,000 deaths annually throughout the world. Several countries in Latin America have introduced the rotavirus vaccine and the majority have epidemiological data to measure impact following vaccine introduction. OBJECTIVE:To asses...

journal_title：Vaccine

authors： De Oliveira LH,Giglio N,Ciapponi A,García Martí S,Kuperman M,Sanwogou NJ,Ruiz-Matus C,Marinho de Sousa MF

更新日期：2013-07-02 00:00:00

abstract：:Designation as a Category B biothreat agent has propelled Coxiella burnetii from a relatively obscure, underappreciated, "niche" microorganism on the periphery of bacteriology, to one of possibly great consequence if actually used in acts of bioterrorism. Advances in the study of this microorganism proceeded slowly, p...

journal_title：Vaccine

authors： Waag DM

更新日期：2007-10-16 00:00:00

abstract：:From 1983 to 1993 two anti-hepatitis B vaccinal strategies were adopted in two small towns of Southern Italy at high incidence for HBV infections: Afragola (prevalence of HBsAg carriers of 13.4%) and Frattamaggiore (prevalence of HBsAg carriers of 12.9%). In Afragola, the universal vaccination of infants in their firs...

journal_title：Vaccine

authors： Da Villa G,Picciottoc L,Elia S,Peluso F,Montanaro F,Maisto T

更新日期：1995-09-01 00:00:00

abstract：:In some cases of atopic dermatitis (AD), a possible pathological contribution to disease development by Candida albicans (C. albicans) has been suggested. AD patients with severe symptoms showing positive capsulated hydrolic carrier polymer radioallergosorbent test (CAP-RAST) against C. albicans demonstrated significa...

journal_title：Vaccine

authors： Suenobu N,Kweon MN,Kiyono H

更新日期：2002-07-26 00:00:00

abstract：:Buffalopox virus (BPXV), an Indian variant of vaccinia virus (VACV), is a zoonotic agent and affects buffaloes, cattle and humans. A27L is one of the conserved major immuno-dominant envelope proteins of orthopox viruses (OPVs) involved in viral entry/maturation and elicits neutralizing antibodies. In this study, the A...

journal_title：Vaccine

authors： Kumar A,Yogisharadhya R,Bhanuprakash V,Venkatesan G,Shivachandra SB

更新日期：2015-10-05 00:00:00

abstract：:The need to enhance the immunogenicity of purified subunit antigens and modulate resulting immune responses has prompted the development of new adjuvants. Here, the ability of CpG oligodeoxynucleotides (ODN), a bovine host defence peptide indolicidin, and polyphosphazene to synergistically combine and enhance innate a...

journal_title：Vaccine

authors： Kovacs-Nolan J,Latimer L,Landi A,Jenssen H,Hancock RE,Babiuk LA,van Drunen Littel-van den Hurk S

更新日期：2009-03-23 00:00:00

abstract：:Immunization of pregnant women against influenza is a promising strategy to protect the mother, fetus, and young infant from influenza-related diseases. The burden of influenza during pregnancy, the vaccine immunogenicity during this period, and the robust influenza vaccine safety database underpin recommendations tha...

journal_title：Vaccine

authors： Ortiz JR,Neuzil KM,Ahonkhai VI,Gellin BG,Salisbury DM,Read JS,Adegbola RA,Abramson JS

更新日期：2012-11-26 00:00:00

abstract：:There is an ongoing need for new adjuvants to facilitate development of vaccines against HIV, tuberculosis, malaria and cancer, amongst many others. Unfortunately, the most potent adjuvants are often associated with toxicity and safety issues. Inulin, a plant-derived polysaccharide, has no immunological activity in it...

journal_title：Vaccine

authors： Petrovsky N,Cooper PD

更新日期：2015-11-04 00:00:00

abstract：:Influenza A/H1N1 new vaccine helps control disease spread. Cross-sectional survey was conducted at PHC & Emergency Departments in Qatar to determine influenza A/H1N1 vaccination rate among HCWs and associated factors, 523 HCWs were enrolled. The study showed that 13.4% HCWs received vaccination. Feeling protected stro...

journal_title：Vaccine

authors： Alkuwari MG,Aziz NA,Nazzal ZA,Al-Nuaimi SA

更新日期：2011-03-03 00:00:00

abstract：BACKGROUND AND PURPOSE:Varicella disease is a risk factor for pediatric Arterial Ischemic Stroke (AIS). Isolated case reports have emerged suggesting that varicella vaccination may also pose a risk for AIS. METHODS:This retrospective population-based cohort study assessed the risk of AIS in children who received a var...

journal_title：Vaccine

authors： MacDonald SE,Dover DC,Hill MD,Kirton A,Simmonds KA,Svenson LW

更新日期：2018-05-11 00:00:00

abstract：:Bovine viral diarrhea virus (BVDV) represents a major cattle disease with multiple forms including fetal infections resulting in persistently infected (PI) cattle. The objectives of this study were to investigate the immune response to six vaccines, five modified live viral (MLV) and one killed vaccine containing BVDV...

journal_title：Vaccine

authors： Fulton RW,Cook BJ,Payton ME,Burge LJ,Step DL

更新日期：2020-05-19 00:00:00

abstract：:Leptospirosis is a zoonotic disease affecting animals and humans worldwide. Leptospiral infection in cattle can cause reproductive failure and reduced weight gain, and importantly, infection represents a significant disease risk for farmers. Current bacterin vaccines offer protection that is short-lived and restricted...

journal_title：Vaccine

authors： Murray GL,Lo M,Bulach DM,Srikram A,Seemann T,Quinsey NS,Sermswan RW,Allen A,Adler B

更新日期：2013-01-07 00:00:00

abstract：OBJECTIVES:To identify predictors of: uptake of the childhood influenza vaccine in the 2015-2016 influenza season, parental perceptions of side-effects from the influenza vaccine and intention to vaccinate one's child for influenza in the 2016-2017 influenza season. DESIGN:Cross-sectional online survey. SETTING:Data ...

journal_title：Vaccine

authors： Smith LE,Webster RK,Weinman J,Amlôt R,Yiend J,Rubin GJ

更新日期：2017-04-04 00:00:00

abstract：BACKGROUND:The combined hexavalent diphtheria-tetanus-pertussis-hepatitis B-inactivated poliomyelitis - Haemophilus influenzae type b conjugate vaccine (Infanrix hexa™; DTPa-HBV-IPV/Hib: GlaxoSmithKline Vaccines) induces robust responses to the HBV component when administered at 3, 5 and 11-12 months of age. We assesse...

journal_title：Vaccine

authors： Avdicova M,Crasta PD,Hardt K,Kovac M

更新日期：2015-05-28 00:00:00

abstract：:Dendritic cells (DC) play an integral role in plasmid DNA vaccination. However, the interaction between plasmid DNA and DC in vivo is incompletely understood. In this report, we utilise the sheep pseudoafferent cannulation model to examine the interaction between plasmid DNA encoding enhanced green fluorescent protein...

journal_title：Vaccine

authors： Watkins C,Hopkins J,Harkiss G

更新日期：2005-07-21 00:00:00

abstract：:The stockpiling of live vaccinia virus vaccines has enhanced biopreparedness against the intentional or accidental release of smallpox. Ongoing research on future generation smallpox vaccines is providing key insights into protective immune responses as well as important information about subunit-vaccine design strate...

journal_title：Vaccine

authors： Xiao Y,Zeng Y,Alexander E,Mehta S,Joshi SB,Buchman GW,Volkin DB,Middaugh CR,Isaacs SN

更新日期：2013-01-02 00:00:00