Identifying barriers and drivers to vaccination: A qualitative interview study with health workers in the Federation of Bosnia and Herzegovina.

Abstract:

BACKGROUND:Vaccination coverage in Bosnia and Herzegovina has been declining over recent years. A World Health Organization Tailoring Immunization Programmes (TIP) project is underway to gain insights into the underlying reasons for this, to develop tailored interventions. As part of TIP, this study aimed to investigate the views of health workers on their barriers and drivers to positive childhood vaccination practices. METHODS:Face-to-face qualitative interviews explored 38 health workers' views on vaccination coverage, their vaccination attitudes, and system, programme and institutional influences on their vaccination practices. The data were analysed using content analysis and organised by the COM (Capability, Opportunity and Motivation) factors. FINDINGS:Very few differences in barriers and drivers were evident between high and low coverage primary care centres or across different professional roles. Capability: Drivers included awareness of the risks of low vaccination coverage, regular use of the Rulebook and Order, knowledge of how to advise parents on mild side effects and recognition of the importance of good communication with parents. Key barriers were the use of false contraindications to postpone vacination and poor skills in tailoring communication with parents. Opportunity: Drivers were sufficient time for adminstering vaccination and good availability of vaccines. Several barriers were evident: lack of implementation of mandatory vaccination, no uniform recall and reminder system or system for detecting under-vaccinated children, staff shortages and lack of time to discuss vaccination with parents. MOTIVATION:Drivers were a belief in the value, safety and effectiveness of vaccination and seeing that they have an important role to play. Barriers were a tendency to blame external factors e.g. anti-vax movement and a fear of being blamed for adverse events. CONCLUSIONS:The study identified complex and inter-related barriers and drivers to health worker positive vaccination practices. These insights will now inform a process to identify and prioritize interventions.

journal_name

Vaccine

journal_title

Vaccine

authors

Musa S,Skrijelj V,Kulo A,Habersaat KB,Smjecanin M,Primorac E,Becirovic D,Jackson C

doi

10.1016/j.vaccine.2020.01.025

subject

Has Abstract

pub_date

2020-02-18 00:00:00

pages

1906-1914

issue

8

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(20)30040-2

journal_volume

38

pub_type

杂志文章

相关文献

VACCINE文献大全
  • Synergistic action of cholera toxin B subunit (and Escherichia coli heat-labile toxin B subunit) and a trace amount of cholera whole toxin as an adjuvant for nasal influenza vaccine.

    abstract::Cholera toxin B subunit (CTB) and Escherichia coli heat-labile toxin (LTB) (2 micrograms), each supplemented with a trace amount of cholera toxin (CT) (0.02-20 ng), were examined for the adjuvant effect on antibody (Ab) response against influenza inactivated HA (haemagglutinin) vaccine in Balb/c mice. Each mouse recei...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/0264-410x(94)90118-x

    authors: Tamura S,Yamanaka A,Shimohara M,Tomita T,Komase K,Tsuda Y,Suzuki Y,Nagamine T,Kawahara K,Danbara H

    更新日期:1994-04-01 00:00:00

  • Economic benefits for the family of inactivated subunit virosomal influenza vaccination of healthy children aged 3-14 years during the annual health examination in private paediatric offices.

    abstract::Taking the results of a prospective cohort study by our group that evaluated the effectiveness of the inactivated subunit virosomal influenza vaccine (Inflexal V), Crucell-Berna) in the prevention of influenza-related diseases and the reduction of its negative economic consequences, the economic costs and benefits for...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2009.01.053

    authors: Salleras L,Navas E,Domínguez A,Ibáñez D,Prat A,Garrido P,Asenjo MA,Torner N

    更新日期:2009-05-26 00:00:00

  • The quest for trials on the efficacy of human vaccines. Results of the handsearch of Vaccine.

    abstract::We report the results of the handsearch of all the issues of Vaccine from 1983 to 1994 to identify randomized and controlled clinical trials (RCTs and CCTs) with the aim of setting up a Cochrane data base of vaccine trials. We read 1119 original papers and located 231 trials of which 117 (50.6%) were RCTs and 114 (49....

    journal_title:Vaccine

    pub_type: 杂志文章,meta分析

    doi:10.1016/0264-410x(95)00247-x

    authors: Jefferson T,Jefferson V

    更新日期:1996-04-01 00:00:00

  • An assessment of parents' childhood immunization beliefs, intentions, and behaviors using a smartphone panel.

    abstract:INTRODUCTION:It is important to quickly identify parent beliefs, intentions, and behaviors toward childhood vaccination, especially parents of children 19 to 35 months. This paper describes parental immunization beliefs, intentions, and behaviors; assesses the relationships between beliefs and intentions regarding chil...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2020.01.032

    authors: Boyle J,Berman L,Nowak GJ,Iachan R,Middleton D,Deng Y

    更新日期:2020-02-28 00:00:00

  • Construction and in vitro characterization of a molecularly cloned human immunodeficiency virus type 1 library.

    abstract::Development of a safe and effective vaccine against human immunodeficiency virus (HIV) is urgent, but many concerns regarding the safety and efficacy of the currently developing vaccines remain. A major hindrance in HIV vaccine development is the genetic diversity, a hallmark of HIV biology, and a poor understanding o...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/s0264-410x(01)00429-7

    authors: Mukai T,Kurosu T,Kinomoto M,Komoto S,Shiraga M,Auwanit W,Ikuta K

    更新日期:2002-01-15 00:00:00

  • Attitudes towards vaccination against seasonal influenza of health-care workers in primary health-care settings in Greece.

    abstract::Vaccination of health-care workers (HCWs) against seasonal influenza has been consistently recommended worldwide in order to prevent nosocomial transmission and ensure delivery of health-care services during outbreaks. We describe the effects of a nationwide campaign to promote influenza vaccination among HCWs working...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2010.06.108

    authors: Dedoukou X,Nikolopoulos G,Maragos A,Giannoulidou S,Maltezou HC

    更新日期:2010-08-23 00:00:00

  • Avian influenza virus: of virus and bird ecology.

    abstract::The recent introductions of highly pathogenic avian influenza (HPAI) H5N1 virus in wild birds and its subsequent spread throughout Asia, the Middle East, Africa and Europe has put a focus on the role of wild birds in the geographical spread of HPAI H5N1 virus. Large-scale surveillance programs are ongoing to determine...

    journal_title:Vaccine

    pub_type: 杂志文章,评审

    doi:10.1016/j.vaccine.2009.02.082

    authors: Munster VJ,Fouchier RA

    更新日期:2009-10-23 00:00:00

  • Characterization of Schistosoma mansoni 44.7/56.8 kDa egg antigens recognized by human monoclonal antibodies which induce protection against experimental infection and proliferation of peripheral blood mononuclear cells from schistosomiasis patients.

    abstract::We described here the characterization of Schistosoma mansoni egg antigens recognized by human monoclonal antibodies B10 (HmAb-B10) and D5 (HmAb-D5). SDS-PAGE and Western blot analysis revealed that these monoclonals recognized two antigens of M W 44.7/56.8 kDa, with pI of 7.0 and 7.8, respectively. The passive transf...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/s0264-410x(96)00305-2

    authors: Hirsch C,Almeida CA,Doughty BL,Goes AM

    更新日期:1997-06-01 00:00:00

  • Oral cholera vaccine delivery strategy in India: Routine or campaign?-A scoping review.

    abstract::Oral Cholera Vaccine (OCV) has been recognized as an adjunct tool for prevention and control of cholera. However, policy directions are currently unavailable in India to guide the vaccine delivery. We conducted a scoping review to inform the policy about the scopes and challenges of different strategic choices of OCV ...

    journal_title:Vaccine

    pub_type: 杂志文章,评审

    doi:10.1016/j.vaccine.2019.07.082

    authors: Ray A,Sarkar K,Haldar P,Ghosh R

    更新日期:2020-02-29 00:00:00

  • Approaches to improved influenza vaccination.

    abstract::Inactivated influenza vaccine (Ivac) has had an important impact on reducing attack rates of influenza and reducing the severity of illness amongst the vaccinees who still acquire infection. Ivac is most efficacious amongst young, otherwise healthy subjects and least effective against elderly at high risk. This is in ...

    journal_title:Vaccine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0264-410x(99)00508-3

    authors: Betts RF,Treanor JJ

    更新日期:2000-02-25 00:00:00

  • Antibody persistence and booster response in adolescents and young adults 4 and 7.5 years after immunization with 4CMenB vaccine.

    abstract:BACKGROUND:Data on duration of protection against invasive meningococcal disease post-vaccination with the recombinant, 4-component, meningococcal serogroup B vaccine (4CMenB) are limited. We evaluated bactericidal activity persistence in adolescents/young adults up to 7.5 years post-primary vaccination with 4CMenB, an...

    journal_title:Vaccine

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.vaccine.2018.12.059

    authors: Nolan T,Santolaya ME,de Looze F,Marshall H,Richmond P,Henein S,Rheault P,Heaton K,Perrett KP,Garfield H,Gupta A,Ferguson M,D'Agostino D,Toneatto D,O'Ryan M

    更新日期:2019-02-21 00:00:00

  • Prospects for preventing infant invasive GBS disease through maternal vaccination.

    abstract::Group B streptococcus (GBS) is a leading cause of neonatal sepsis, with the highest incidence (1.3 per 1000 live births) reported from Africa. Although the incidence of invasive GBS disease is reportedly low in South Asia, there is disconnect between prevalence of maternal recto-vaginal colonization and the incidence ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2017.02.025

    authors: Madhi SA,Dangor Z

    更新日期:2017-08-16 00:00:00

  • Detection by ELISA of antibodies to Japanese encephalitis virus nonstructural 1 protein induced in subclinically infected humans.

    abstract::Japanese encephalitis (JE) is a fatal mosquito-borne disease that is vaccine-preventable. The natural infection rate is a critical factor for evaluations of the necessity for vaccination. Detection of antibodies to virus nonstructural (NS) proteins is a theoretical strategy to survey natural infections among populatio...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2009.09.064

    authors: Konishi E,Kitai Y

    更新日期:2009-11-23 00:00:00

  • Evaluation of potentially achievable vaccination coverage with simultaneous administration of vaccines among children in the United States.

    abstract:BACKGROUND:Routine administration of all age-appropriate doses of vaccines during the same visit is recommended for children by the National Vaccine Advisory Committee (NVAC) and the Advisory Committee on Immunization Practices (ACIP). METHODS:Evaluate the potentially achievable vaccination coverage for ≥4 doses of di...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2016.04.097

    authors: Zhao Z,Smith PJ,Hill HA

    更新日期:2016-06-08 00:00:00

  • Immunogenicity of virus-like particles containing modified human immunodeficiency virus envelope proteins.

    abstract::Extensive glycosylation and variable loops of the HIV envelope protein (Env) are reported to shield some neutralizing epitopes. Here, we investigated the immunogenicity of mutated HIV Envs presented in virus-like particles (VLPs). We immunized mice with simian human immunodeficiency virus (SHIV) VLPs containing mutant...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2007.01.107

    authors: Quan FS,Sailaja G,Skountzou I,Huang C,Vzorov A,Compans RW,Kang SM

    更新日期:2007-05-10 00:00:00

  • The benefits of redesigning Benin's vaccine supply chain.

    abstract:INTRODUCTION:New vaccine introductions have put strains on vaccine supply chains around the world. While increasing storage and transportation may be the most straightforward options, it is also important to consider what financial and operational benefits can be incurred. In 2012, suboptimal vaccine coverage and impen...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2014.04.090

    authors: Brown ST,Schreiber B,Cakouros BE,Wateska AR,Dicko HM,Connor DL,Jaillard P,Mvundura M,Norman BA,Levin C,Rajgopal J,Avella M,Lebrun C,Claypool E,Paul P,Lee BY

    更新日期:2014-07-07 00:00:00

  • Effect of adjuvants and route of immunizations on the immune response to recombinant plague antigens.

    abstract::In this study, we compare four different adjuvants, LT(R192G), CpG ODN, MPL((R))TDM, and alum, for their ability to affect the magnitude, distribution, and duration of antibody responses against F1-V, the lead-candidate antigen for the next generation vaccine against plague, in a murine model. In addition, three diffe...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2007.09.030

    authors: Uddowla S,Freytag LC,Clements JD

    更新日期:2007-11-19 00:00:00

  • Post-licensure safety surveillance of 23-valent pneumococcal polysaccharide vaccine in the Vaccine Adverse Event Reporting System (VAERS), 1990-2013.

    abstract:BACKGROUND:23-Valent pneumococcal polysaccharide vaccine, trade name Pneumovax(®)23 (PPSV23), has been used for decades in the Unites States and has an extensive clinical record. However, limited post-licensure safety assessment has been conducted. OBJECTIVE:To analyze reports submitted to the Vaccine Adverse Event Re...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2016.04.021

    authors: Miller ER,Moro PL,Cano M,Lewis P,Bryant-Genevier M,Shimabukuro TT

    更新日期:2016-05-27 00:00:00

  • Adjuvant activity of fish type I interferon shown in a virus DNA vaccination model.

    abstract::There is a need for more efficient vaccines to combat viral diseases of Atlantic salmon and other farmed fish. DNA vaccines are highly effective against salmonid rhabdoviruses, but have shown less effect against other viruses. In the present work we have studied if type I IFNs might be used as adjuvants in fish DNA va...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2015.03.093

    authors: Chang CJ,Sun B,Robertsen B

    更新日期:2015-05-15 00:00:00

  • Serological responses of rams to a Brucella ovis-vitamin E adjuvant vaccine.

    abstract::Rams which were vaccinated at 6-8 months of age with a water-in-oil Brucella ovis-vitamin E adjuvant vaccine had significantly higher serum antibody levels than rams vaccinated with a commercial B. ovis bacterin or B. melitensis Rev 1. The adjuvant vaccine did not cause abscesses at the site of injection as some water...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/0264-410x(91)90111-i

    authors: Tengerdy RP,Ameghino E,Riemann H

    更新日期:1991-04-01 00:00:00

  • Vaccination with a piggyBac plasmid with transgene integration potential leads to sustained antigen expression and CD8(+) T cell responses.

    abstract::DNA vaccination with plasmid has conventionally involved vectors designed for transient expression of antigens in injected tissues. Next generation plasmids are being developed for site-directed integration of transgenes into safe sites in host genomes and may provide an innovative approach for stable and sustained ex...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2014.01.063

    authors: Bertino P,Urschitz J,Hoffmann FW,You BR,Rose AH,Park WH,Moisyadi S,Hoffmann PR

    更新日期:2014-03-26 00:00:00

  • Ultraviolet-C irradiation for inactivation of viruses in foetal bovine serum.

    abstract::Foetal Bovine Serum (FBS) and porcine trypsin are one of the essential raw materials used in the manufacturing of cell culture based viral vaccines. Being from animal origin, these raw materials can potentially contaminate the final product by known or unknown adventitious agents. The issue is more serious in case of ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2018.06.008

    authors: Vaidya V,Dhere R,Agnihotri S,Muley R,Patil S,Pawar A

    更新日期:2018-07-05 00:00:00

  • Influenza vaccination policies for health workers in low-income and middle-income countries: A cross-sectional survey, January-March 2020.

    abstract:INTRODUCTION:The World Health Organization (WHO) recommends vaccination of health workers against influenza, but uptake in low-resource settings remains low. To complement routine global data collection efforts we conducted a detailed survey on influenza vaccination policies for health workers in low-income and middle-...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2020.10.001

    authors: Maltezou HC,Theodoridou K,Tseroni M,Raftopoulos V,Bolster A,Kraigsley A,Bresee J,Lambach P

    更新日期:2020-11-03 00:00:00

  • Influenza vaccination rates in Ontario children: implications for universal childhood vaccination policy.

    abstract::The aims of this study were to estimate influenza vaccination coverage for children during the 2006-2007 influenza season in Ontario, Canada, where universal vaccination is available, and to compare the rate among children aged 6-23 months with corresponding rates from other Canadian provinces that specifically target...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2009.02.017

    authors: Moran K,Maaten S,Guttmann A,Northrup D,Kwong JC

    更新日期:2009-04-14 00:00:00

  • Optimization and scale-up of cell culture and purification processes for production of an adenovirus-vectored tuberculosis vaccine candidate.

    abstract::Tuberculosis (TB) is the second leading cause of death by infectious disease worldwide. The only available TB vaccine is the Bacille Calmette-Guerin (BCG). However, parenterally administered Mycobacterium bovis BCG vaccine confers only limited immune protection from pulmonary tuberculosis in humans. There is a need fo...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2016.04.090

    authors: Shen CF,Jacob D,Zhu T,Bernier A,Shao Z,Yu X,Patel M,Lanthier S,Kamen A

    更新日期:2016-06-17 00:00:00

  • Direct immunization of the abomasum or rectum of goats induces local lymph node responses against Haemonchus contortus mucosal antigens.

    abstract::We investigated several methods to immunize the abomasum (fourth and gastric stomach) of kid goats by direct (abomasal) or distal (rectal or nasal) routes utilizing mucosal antigens isolated from the abomasal parasite, Haemonchus contortus. Direct (ultrasound guided), immunization of the abomasal mucosa together with ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2011.02.003

    authors: Jasmer DP,Brown WC,Parish S

    更新日期:2011-04-05 00:00:00

  • Therapeutic immunisation plus cytokine and hormone therapy improves CD4 T-cell counts, restores anti-HIV-1 responses and reduces immune activation in treated chronic HIV-1 infection.

    abstract:BACKGROUND:This randomised, open label, phase I, immunotherapeutic study investigated the effects of interleukin (IL)-2, granulocyte-macrophage colony-stimulating factor (GM-CSF), recombinant human growth hormone (rhGH), and therapeutic immunisation (a Clade B DNA vaccine) on combination antiretroviral therapy (cART)-t...

    journal_title:Vaccine

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.vaccine.2014.09.072

    authors: Herasimtschuk A,Downey J,Nelson M,Moyle G,Mandalia S,Sikut R,Adojaan M,Stanescu I,Gotch F,Imami N

    更新日期:2014-12-05 00:00:00

  • Characterisation of a protective linear B cell epitope against feline parvoviruses.

    abstract::Monoclonal antibody 3C9 was the starting material in the definition of the epitope that led to the synthesis of the first efficient peptide vaccine against a viral disease (canine parvovirus) in the natural host (dog). In this report, we have analysed the specificity of the antibody at the single amino acid level and ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/s0264-410x(00)00526-0

    authors: Langeveld JP,Martinez-Torrecuadrada J,Boshuizen RS,Meloen RH,Ignacio Casal J

    更新日期:2001-03-21 00:00:00

  • Accelerated and long term stability study of Pfs25-EPA conjugates adjuvanted with Alhydrogel®.

    abstract::Pfs25, a Plasmodium falciparum surface protein expressed during zygote and ookinete stages in infected mosquitoes, is a lead transmission-blocking vaccine candidate against falciparum malaria. To enhance immunogenicity, recombinant Pfs25 was chemically conjugated to recombinant nontoxic Pseudomonas aeruginosa ExoProte...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2017.04.067

    authors: Zhu D,Wu Y,McClellan H,Dai W,Rausch K,Jones D,Aebig J,Barnafo E,Butler B,Lambert L,Narum DL,Duffy PE

    更新日期:2017-05-31 00:00:00

  • Chemistry of a new investigational quadrivalent meningococcal conjugate vaccine that is immunogenic at all ages.

    abstract::Meningococcal disease is a serious medical condition that can prove fatal within hours in otherwise healthy individuals. Disease incidence is highest in infants, yet there is no broadly protective quadrivalent vaccine that covers this age group. A new investigational quadrivalent meningococcal glycoconjugate vaccine a...

    journal_title:Vaccine

    pub_type: 杂志文章,评审

    doi:10.1016/j.vaccine.2009.07.036

    authors: Bröker M,Dull PM,Rappuoli R,Costantino P

    更新日期:2009-09-18 00:00:00