Evaluation of adenovirus 19a as a novel vector for mucosal vaccination against influenza A viruses.

abstract：BACKGROUND:Worldwide coverage of hepatitis B (HB) vaccination is increasing. This should be considered when determining the best strategy for catch-up HB vaccination in migrant children, who rarely have written proof of past immunizations. This study aimed to estimate HB vaccine protection, chronic HB prevalence and to...

journal_title：Vaccine

authors： Fougère Y,El Houss S,Suris JC,Rouvenaz-Defago S,Miletto D,Von der Weid L,Willen F,Williams-Smith JA,Gehri M,Crisinel PA

更新日期：2018-07-16 00:00:00

abstract：:The Decade of Vaccines (DoV) initiative, launched in 2010, has as its mission "to extend, by 2020 and beyond, the full benefits of immunization to all people, regardless of where they are born, who they are, or where they live". Through their life-saving vaccines, the research-based vaccine companies represented by th...

journal_title：Vaccine

authors： Keith JA,Agostini Bigger L,Arthur PA,Maes E,Daems R

更新日期：2013-04-18 00:00:00

abstract：:H5N1, highly pathogenic avian influenza poses, a threat to animal and human health. Rapid changes in H5N1 viruses require periodic reformulation of the conventional strain-matched vaccines, thus emphasizing the need for a broadly protective influenza vaccine. Here, we constructed BV-Dual-3M2e-LTB, a recombinant baculo...

journal_title：Vaccine

authors： Zhang J,Fan HY,Zhang Z,Zhang J,Zhang J,Huang JN,Ye Y,Liao M

更新日期：2016-01-27 00:00:00

abstract：:There is accumulating evidence that many invertebrates including insects can acquire enhanced immune protection against subsequently pathogens infection through immune priming. However, whether the toxin protein from pathogenic bacteria can induce such priming response remains unclear. Here we cloned, expressed and pu...

journal_title：Vaccine

authors： Wu G,Yi Y,Sun J,Li M,Qiu L

更新日期：2015-11-17 00:00:00

abstract：:After a single injection of Typhim Vi (typhoid Vi polysaccharide vaccine), serum antibody concentrations were monitored for 3 years in 37 adults who resided where typhoid fever was not endemic. Anti-Vi antibody concentrations declined progressively during the study, to levels that support the current US recommendation...

journal_title：Vaccine

authors： Froeschle JE,Decker MD

更新日期：2010-02-10 00:00:00

abstract：INTRODUCTION:Despite increased use of vaccine in routine immunisation, rotavirus remains a major cause of acute gastroenteritis (AGE) in low-income countries. We describe rotavirus prevalence and hospitalisation in Malawi pre and four years post vaccine introduction; provide updated vaccine effectiveness (VE) estimates...

journal_title：Vaccine

authors： Bennett A,Pollock L,Jere KC,Pitzer VE,Parashar U,Tate JE,Heyderman RS,Mwansambo C,French N,Nakagomi O,Iturriza-Gomara M,Everett D,Cunliffe NA,Bar-Zeev N,VacSurv Consortium.

更新日期：2018-11-12 00:00:00

abstract：UNLABELLED:Due to the high burden of pneumonia in Indonesia, the inclusion of pneumococcal conjugate vaccine (PCV) into Indonesia's National Immunization Program (NIP) is recommended by World Health Organization. Prior to the introduction of new vaccines, it is imperative to assess the perceptions of the public and med...

journal_title：Vaccine

authors： Harjaningrum AT,Kartasasmita C,Orne-Gliemann J,Jutand MA,Goujon N,Koeck JL

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:We have previously developed a recombinant avian avulavirus serotype 10 (rAAvV-10/HA) expressing the hemagglutinin (HA) gene of a highly pathogenic avian influenza virus (HPAIV) as an emergency vaccine for poultry. rAAvV-10/HA can overcome the activity of the anti-AAvV-1 (Newcastle disease virus) antibody ac...

journal_title：Vaccine

authors： Tsunekuni R,Tanikawa T,Nakaya T,Saito T

更新日期：2020-01-22 00:00:00

abstract：:Assuming that the level of Bacille Calmette Guerin (BCG) coverage gives a measure of access to immunisation services, it is possible to derive what fraction of infants are not immunised against measles due to under-utilisation of existing services (rather than unavailability of services). According to the most recent ...

journal_title：Vaccine

authors： Edmunds WJ,Gay NJ,Henao Restrepo AM,Olivé JM,Bele O

更新日期：2001-10-12 00:00:00

abstract：:Buffalopox virus (BPXV), an Indian variant of vaccinia virus (VACV), is a zoonotic agent and affects buffaloes, cattle and humans. A27L is one of the conserved major immuno-dominant envelope proteins of orthopox viruses (OPVs) involved in viral entry/maturation and elicits neutralizing antibodies. In this study, the A...

journal_title：Vaccine

authors： Kumar A,Yogisharadhya R,Bhanuprakash V,Venkatesan G,Shivachandra SB

更新日期：2015-10-05 00:00:00

abstract：:PSMA-VRP is a propagation defective, viral replicon vector system encoding PSMA under phase I evaluation for patients with castration resistant metastatic prostate cancer (CRPC). The product is derived from an attenuated strain of the alphavirus, Venezuelan Equine Encephalitis (VEE) virus, and incorporates multiple re...

journal_title：Vaccine

authors： Slovin SF,Kehoe M,Durso R,Fernandez C,Olson W,Gao JP,Israel R,Scher HI,Morris S

更新日期：2013-01-30 00:00:00

abstract：:We cloned six mycobacterial antigens into a mammalian expression vector as fusion proteins with the enhanced green fluorescent protein (EGFP). Plasmid DNA was injected intramuscularly, and the injection sites were examined 1 week later. Expression of each antigen-EGFP fusion protein was visualized as green fluorescenc...

journal_title：Vaccine

authors： Quinn A,Jiang W,Velaz-Faircloth M,Cobb AJ,Henry SC,Frothingham R

更新日期：2002-08-19 00:00:00

abstract：:Carrier conjugation is commonly used to provide T-cell help for small, linear peptides containing antigen-specific B-cell epitopes. However, carrier conjugation is expensive, variable and often results in adverse side effects if the conjugate is administered repeatedly. To eliminate the need for carrier conjugation, w...

journal_title：Vaccine

authors： O'Hern PA,Liang ZG,Bambra CS,Goldberg E

更新日期：1997-11-01 00:00:00

abstract：:We aim to develop a method that confers rapid protection against foot-and-mouth disease (FMD) by passive immunization with recombinant llama single-domain antibody fragments (VHHs). Previously constructed genetic fusions of two VHHs (VHH2s) that either neutralizes FMDV or binds to porcine immunoglobulin to increase th...

journal_title：Vaccine

authors： Harmsen MM,Fijten HP,Engel B,Dekker A,Eblé PL

更新日期：2009-03-18 00:00:00

abstract：BACKGROUND:To evaluate the potential public health impact of the live attenuated tetravalent Sanofi Pasteur dengue vaccine (CYD-TDV) we analyzed data from the reported clinical trials to calculate vaccine preventable disease incidence (VPDI) and number needed to vaccinate (NNV) based on the licensure indication for per...

journal_title：Vaccine

authors： Gessner BD,Wilder-Smith A

更新日期：2016-04-29 00:00:00

abstract：:Here, we evaluated the modulation of the immune response induced by Hsp90 of Nicotiana benthamiana (NbHsp90.3) against the Maltose Binding Protein (MBP) as a reporter antigen. Equimolar quantities of recombinant proteins were administered in mice as follows: MBP alone (MBP group), a mixture of MBP and rNbHsp90.3 (MBP+...

journal_title：Vaccine

authors： Corigliano MG,Fenoy I,Sander V,Maglioco A,Goldman A,Clemente M

更新日期：2013-12-02 00:00:00

abstract：:Human chorionic gonadotropin (hCG) is synthesized soon after fertilization and is essential for embryonic implantation. A vaccine targeting hCG would be an ideal choice for immuno-contraception; an anti-hCG vaccine developed by Talwar et al., has previously undergone Phase II efficacy trials, providing proof of princi...

journal_title：Vaccine

authors： Purswani S,Talwar GP

更新日期：2011-03-09 00:00:00

abstract：:One of the economically important diseases in the poultry industry is Marek's disease (MD) which is caused by Marek's disease virus (MDV). The use of current vaccines provides protection against clinical signs of MD in chickens. However, these vaccines do not prevent the transmission of MDV to susceptible hosts, hence...

journal_title：Vaccine

authors： Bavananthasivam J,Alkie TN,Astill J,Abdul-Careem MF,Wootton SK,Behboudi S,Yitbarek A,Sharif S

更新日期：2018-06-27 00:00:00

abstract：:Increasing mortality, morbidity and economic costs have been paid to pneumococcal diseases every year. Currently, vaccination is the most promising strategy to reduce the occurrence of pneumococcal infection. In this study, we investigated the protective efficacy of immunization with recombinant DnaJ (hsp40) protein a...

journal_title：Vaccine

authors： Cui Y,Zhang X,Gong Y,Niu S,Yin N,Yao R,Xu W,Li D,Wang H,He Y,Cao J,Yin Y

更新日期：2011-02-17 00:00:00

abstract：:About 10% of health care professionals vaccinated against hepatitis B virus (HBV) fail to develop protective antibodies. We tested the capacity of peripheral blood lymphocytes from 121 health care professionals, including 76 non-responders, to proliferate to four HBV vaccines, examined the proliferating cells' subset,...

journal_title：Vaccine

authors： Jarrosson L,Kolopp-Sarda MN,Aguilar P,Béné MC,Lepori ML,Vignaud MC,Faure GC,Kohler C

更新日期：2004-09-09 00:00:00

abstract：:HIV-1 specific cellular immune responses play a significant part in controlling HIV-1 viral replication and are an important component of an HIV-1 vaccine induced immune response. We reported earlier that recombinant DNA vaccine delivered intramuscularly, and recombinant Listeria monocytogenes, delivered orally induce...

journal_title：Vaccine

authors： Boyer JD,Maciag PC,Parkinson R,Wu L,Lewis MG,Weiner DB,Paterson Y

更新日期：2006-05-22 00:00:00

abstract：:Chitosan is a polysaccharide capable of augmenting immune responses with a proven safety record in animals and humans. These properties make it a potentially attractive agent for the prevention and treatment of infectious disease. Infection by respiratory syncytial virus (RSV) is the leading cause of serious lower res...

journal_title：Vaccine

authors： Muralidharan A,Russell MS,Larocque L,Gravel C,Sauvé S,Chen Z,Li C,Chen W,Cyr T,Rosu-Myles M,Wang L,Li X

更新日期：2019-07-09 00:00:00

abstract：INTRODUCTION:Replication-competent vaccinia viruses (VACVs) show prolonged antigen expression time and greater stimulation of immune responses than their replication-incompetent counterparts. However, there is the potential risk of serious post-vaccination complications, especially for children and immunocompromised in...

journal_title：Vaccine

authors： Zhang Q,Liu Z,Hou J,Wang S,Liu C,Wei M,Liu Y,Shao Y

更新日期：2016-06-24 00:00:00

abstract：PURPOSE:In April 2007, Panama introduced Hepatitis A universal vaccination using a two-dose schedule (Havrix(®)junior; GSK Vaccines, Belgium). We assessed the impact of this hepatitis A vaccine three years after it was recommended for universal mass vaccination in Panama. MATERIALS AND METHODS:Hepatitis A vaccination ...

journal_title：Vaccine

authors： Estripeaut D,Contreras R,Tinajeros O,Castrejón MM,Shafi F,Ortega-Barria E,DeAntonio R

更新日期：2015-06-22 00:00:00

abstract：:During the 2000/2001 influenza season in Japan, children ranging in age from 6 months to 13 years with fever exceeding 37.5 degrees C were recruited. Vaccine efficacy was evaluated by comparing the rates of pre-seasonal vaccination between groups stratified by fever severity. Seven hundred and sixty one patients (33.1...

journal_title：Vaccine

authors： Kamada M,Nagai T,Kumagai T,Igarashi M,Ihara T,Okafuji T,Ochiai H,Sakiyama H,Shimomura K,Suzuki E,Torigoe S,Miyazaki C,Miyata A,Yuri K,Ito Y,Nakayama T,Kase T,Okuno Y

更新日期：2006-04-24 00:00:00

abstract：OBJECTIVE:We investigated whether and to what extent the uptake of the Human Papillomavirus (HPV) vaccine by girls aged 12-18 was related to the cervical cancer screening history of age-appropriate older female household members (assumed to be their mothers) in Flanders (Belgium). METHODS:We studied administrative rec...

journal_title：Vaccine

authors： Lefevere E,Hens N,Theeten H,Van den Bosch K,Beutels P,De Smet F,Van Damme P

更新日期：2011-10-26 00:00:00

abstract：:Salmonella spp. are facultative intracellular pathogens causing localised or systemic infections, in addition to a chronic asymptomatic carrier state. They are of worldwide economic and public health significance. In poultry, which represent important sources of cheap protein throughout the world, fowl typhoid and pul...

journal_title：Vaccine

authors： Zhang-Barber L,Turner AK,Barrow PA

更新日期：1999-06-04 00:00:00

abstract：:Tuberculosis remains a major public health hazard worldwide, with neonates and young infants potentially more susceptible to infection than adults. BCG, the only vaccine currently available, provides some protection against tuberculous meningitis in children but variable efficacy in adults, and is not safe to use in i...

journal_title：Vaccine

authors： Dai G,Rady HF,Huang W,Shellito JE,Mason C,Ramsay AJ

更新日期：2016-12-07 00:00:00

abstract：:We have found out that transfection of the RTG-2 cell line with the viral haemorrhagic septicaemia virus (VHSV) glycoprotein G (G(VHSV))-coding plasmid induces an anti-VHSV state, similar to that induced by poly I:C. Taking the advantage of the constitutive expression of toll-like receptor 9 gene (tlr9) in RTG-2 cells...

journal_title：Vaccine

authors： Ortega-Villaizan M,Chico V,Martinez-Lopez A,Falco A,Perez L,Coll JM,Estepa A

更新日期：2011-01-17 00:00:00

abstract：:Iscoms, with rCTB incorporated via the GM1 receptor, enhanced in mice the mucosal immunogenicity of rCTB as antigen after intranasal (i.n.) administration both by inducing IgA response in the remote intestinal tract mucosa and by a 100-fold increase of the specific IgA locally in the lungs. Iscom-matrix as a separate ...

journal_title：Vaccine

authors： Ekström J,Hu KF,Bengtsson KL,Morein B

更新日期：1999-06-04 00:00:00