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Reduced intradermal test dose of yellow fever vaccine induces protective immunity in individuals with egg allergy.

Abstract：

:The neutralising antibody response after the yellow fever vaccine (YF-17D) skin test was measured in 7 egg allergic persons in whom further vaccination was abandoned because of a strong local urticarial reaction to the YF-17D vaccine test dose. We found that this test dose of 0.1mL of YF-17D vaccine was sufficient to induce a protective antibody response in all 7 subjects. Intradermal injection of 1/5th dose of the yellow fever vaccine appears to be sufficient, in non-allergic as well as allergic persons, and non-inferior to the subcutaneous full dose.

journal_name

Vaccine

journal_title

Vaccine

authors

Roukens AH,Vossen AC,van Dissel JT,Visser LG

doi

10.1016/j.vaccine.2009.02.049

subject

Has Abstract

pub_date

2009-04-21 00:00:00

pages

2408-9

issue

18

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(09)00308-9

journal_volume

27

pub_type

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