Recombinant hemagglutinin protein of rinderpest virus expressed in insect cells induces humoral and cell mediated immune responses in cattle.

abstract：BACKGROUND:Patients with Crohn's disease (CD) have a higher risk of infectious diseases including pneumococcal infections, and the risk increases with immunotherapy. The primary endpoint of this study was to investigate the specific antibody response to two pneumococcal vaccines in CD patients with and without immunosu...

journal_title：Vaccine

authors： Kantsø B,Halkjær SI,Thomsen OØ,Belard E,Gottschalck IB,Jørgensen CS,Krogfelt KA,Slotved HC,Ingels H,Petersen AM

更新日期：2015-10-05 00:00:00

abstract：:Heat shock proteins (HSP) are highly conserved molecules that play important roles in protein folding, assembly of protein complexes and translocation of proteins across cellular compartments, as well as in several immunological processes. In this study, we first immunized susceptible BALB/c and resistant C57BL/6 mice...

journal_title：Vaccine

authors： Rafati S,Gholami E,Hassani N,Ghaemimanesh F,Taslimi Y,Taheri T,Soong L

更新日期：2007-05-22 00:00:00

abstract：BACKGROUND:Although pregnant women are the highest priority group for seasonal influenza vaccination, maternal influenza vaccination rates remain suboptimal. The purpose of this study was to evaluate the effect of a brief education intervention on maternal influenza vaccine uptake. METHODS:During the 2013-14 and 2014-...

journal_title：Vaccine

authors： Wong VWY,Fong DYT,Lok KYW,Wong JYH,Sing C,Choi AY,Yuen CYS,Tarrant M

更新日期：2016-10-17 00:00:00

abstract：:Vaccine hesitancy is increasing and failure to vaccinate is well-recognised in Europe as a contributing factor to outbreaks of infectious diseases. In Lothian and Scotland, low vaccine uptake has been seen in migrants - notably in the Polish group who have arrived since 2004. The recent Vaccine Confidence in European ...

journal_title：Vaccine

authors： Gorman DR,Bielecki K,Willocks LJ,Pollock KG

更新日期：2019-05-06 00:00:00

abstract：:G22, an anti-idiotype single chain antibody screened from human nasopharyngeal carcinoma phage anti-idiotype antibody library, has been already identified by He et al. G22 DNA vaccine was produced by cloning G22 gene and inserting the cloned gene into pcDNA3.1. To investigate the immunogenicity of pcDNA3.1-G22, C57BL/...

journal_title：Vaccine

authors： Luo C,Wang JJ,Li YH,Hu JY,Li GC

更新日期：2010-03-24 00:00:00

abstract：BACKGROUND:Poliomyelitis is endemic in Northern Nigeria where there is continuous transmission of wild poliovirus 1 and 3 (WPV1 and 3) and circulating vaccine derived poliovirus 2 (cVDPV2) resulting in a high number of cases of children with acute flaccid paralysis. The seroprevalence of antibodies to polio serotypes w...

journal_title：Vaccine

authors： Giwa FJ,Olayinka AT,Ogunshola FT

更新日期：2012-11-06 00:00:00

abstract：:To prevent premature dismissal of promising vaccine programs, it is critical to determine if lack of efficacy in the field is due to allele specific-efficacy, rather than to the lack of immunogenicity of the candidate antigen. Here we use samples collected during a field trial of the AMA1-based FMP2.1/AS02A malaria va...

journal_title：Vaccine

authors： Ouattara A,Niangaly A,Adams M,Coulibaly D,Kone AK,Traore K,Laurens MB,Tolo Y,Kouriba B,Diallo DA,Doumbo OK,Plowe CV,Djimdé A,Thera MA,Laufer MK,Takala-Harrison S,Silva JC

更新日期：2020-07-31 00:00:00

abstract：:Vaccines are needed to control zoonotic Schistosoma japonicum infection and several vaccine candidates have now been identified. Two of these (Sj28GST and Sj23) have shown particular promise in sheep when injected with Freund's adjuvants. The objective of the present work was to find a vaccine formulation which may ha...

journal_title：Vaccine

authors： Shi F,Zhang Y,Ye P,Lin J,Cai Y,Shen W,Bickle QD,Taylor MG

更新日期：2001-11-12 00:00:00

abstract：:The PEDVAC study is the first trial designed to analyze safety and immunogenicity of a therapeutic vaccination with a multiclade multigene HIV DNA vaccine (HIVIS) in infected children. Twenty HIV-1 vertically infected children (6-16 years of age), on stable antiretroviral treatment for at least 6 months with HIV-1 RNA...

journal_title：Vaccine

authors： Palma P,Romiti ML,Li Pira G,Montesano C,Mora N,Aquilani A,Santilli V,Tchidjou HK,Ivaldi F,Giovannelli L,Pontrelli G,Borra G,Blomberg P,Gudmundsdotter L,Bråve A,Montano M,Bernardi S,Manca F,Wahren B,Rossi P

更新日期：2011-09-09 00:00:00

abstract：:Japanese encephalitis (JE) vaccine has been used in childhood immunization programmes in Asia for many years. Also travellers from other parts of the world have been vaccinated before travelling in Asian countries. Recommendations for the use of JE vaccine are still debated because severe cases of adverse reactions ha...

journal_title：Vaccine

authors： Plesner AM,Rønne T

更新日期：1997-08-01 00:00:00

abstract：:Technological advancements, including landmark innovations in vaccinology through molecular virology, and significant transformation and changes in the society have taken place since the eradication of smallpox thirty years ago. The success with eradicating smallpox gave confidence for initiating the eradication of ot...

journal_title：Vaccine

authors： Tomori O

更新日期：2011-12-30 00:00:00

abstract：:The outer capsid protein VP4 is an important target for the development of a recombinant rotavirus vaccine because it mediates the attachment and penetration of rotavirus. Due to the poor solubility of full-length VP4, VP8 was explored as candidate rotavirus vaccines in the past years. In previous studies, it has been...

journal_title：Vaccine

authors： Li Y,Xue M,Yu L,Luo G,Yang H,Jia L,Zeng Y,Li T,Ge S,Xia N

更新日期：2018-04-12 00:00:00

abstract：INTRODUCTION:Black and Hispanic men are diagnosed with more HPV-related cancers and at later stages compared to other racial/ethnic groups. Physician communication with men about HPV vaccination may be beneficial to increasing HPV vaccinations and decreasing HPV transmission. The purpose of this study was to examine HP...

journal_title：Vaccine

authors： Cooper DL,Hernandez ND,Rollins L,Akintobi TH,McAllister C

更新日期：2017-05-09 00:00:00

abstract：:Streptococcus pneumoniae is one of the leading bacterial pathogens causing invasive disease and non-invasive infections at both extremes of life: in children younger than 5 years and in elderly persons of 65 years or more. Pneumococcal infections result in substantial morbidity and mortality among children under 5 yea...

journal_title：Vaccine

authors： Arguedas A,Soley C,Abdelnour A

更新日期：2011-09-14 00:00:00

abstract：:Yellow fever (YF) is an endemic disease in some tropical areas of South America and Africa that presents lethality rate between 20 and 50%. There is no specific treatment and to control this disease a highly effective live-attenuated egg based vaccine is widely used for travelers and residents of areas where YF is end...

journal_title：Vaccine

authors： Pato TP,Souza MC,Silva AN,Pereira RC,Silva MV,Caride E,Gaspar LP,Freire MS,Castilho LR

更新日期：2014-05-19 00:00:00

abstract：BACKGROUND:Invasive meningococcal disease (IMD) is a major cause of bacterial meningitis and septicaemia although infection by some serogroups may be prevented through vaccination. We aimed to describe the epidemiology of IMD in EU/EEA countries during 2004-2014 to monitor serogroup- and age-specific trends, and compar...

journal_title：Vaccine

authors： Whittaker R,Dias JG,Ramliden M,Ködmön C,Economopoulou A,Beer N,Pastore Celentano L,ECDC network members for invasive meningococcal disease.

更新日期：2017-04-11 00:00:00

abstract：:Marek's disease virus (MDV) encodes a basic leucine zipper oncoprotein, Meq, which structurally resembles jun/fos family of transcriptional activators. It has been clearly demonstrated that deletion of Meq results in loss of transformation and oncogenic capacity of MDV. The rMd5ΔMeq virus provided superior protection ...

journal_title：Vaccine

authors： Lee LF,Heidari M,Zhang H,Lupiani B,Reddy SM,Fadly A

更新日期：2012-07-20 00:00:00

abstract：:The apical membrane antigen 1 (AMA1) of malaria parasites is a leading vaccine candidate. Its expression in merozoites and sporozoites and its importance for erythrocyte and hepatocyte invasion underline the significance of both humoral and cellular immunities against this antigen in malaria protection. We have genera...

journal_title：Vaccine

authors： Miao J,Li X,Liu Z,Xue C,Bujard H,Cui L

更新日期：2006-09-11 00:00:00

abstract：:Pneumococcal meningitis in the African meningitis belt is primarily caused by Streptococcus pneumoniae serotype 1, a serotype contained in the 13-valent pneumococcal conjugate vaccine (PCV13). In 2014, Niger introduced PCV13 with doses given at 6, 10, and 14 weeks of age. We leveraged existing meningitis surveillance ...

journal_title：Vaccine

authors： Ousmane S,Kobayashi M,Seidou I,Issaka B,Sharpley S,Farrar JL,Whitney CG,Ouattara M

更新日期：2020-05-13 00:00:00

abstract：BACKGROUND:China is the most populous country in the world, with an annual birth cohort of approximately 16 million, requiring an average of 500 million vaccine doses administered annually. In China, over 30 domestic and less than 10 overseas vaccine manufacturers supply over 60 licensed vaccine products, representing ...

journal_title：Vaccine

authors： Guo B,Page A,Wang H,Taylor R,McIntyre P

更新日期：2013-01-11 00:00:00

abstract：:Early studies using DNA immunization suggest the potential benefits of this form of immunization including: long-lived immunity, a broad spectrum of immune responses (both cell-mediated immunity and humoral responses) and the simultaneous induction of immunity to a variety of pathogens through the use of multivalent v...

journal_title：Vaccine

authors： van Drunen Littel-van den Hurk S,Loehr BI,Babiuk LA

更新日期：2001-03-21 00:00:00

abstract：:Vaccination of health-care workers (HCWs) against seasonal influenza has been consistently recommended worldwide in order to prevent nosocomial transmission and ensure delivery of health-care services during outbreaks. We describe the effects of a nationwide campaign to promote influenza vaccination among HCWs working...

journal_title：Vaccine

authors： Dedoukou X,Nikolopoulos G,Maragos A,Giannoulidou S,Maltezou HC

更新日期：2010-08-23 00:00:00

abstract：:Pseudomonas aeruginosa is a common cause of infection in immunocompromised patients and is the major contributor to morbidity in individuals with cystic fibrosis (CF). The antibiotic resistance shown by this pathogen and morbidity in patients with chronic infection has encouraged investigations into the development of...

journal_title：Vaccine

authors： Thomas LD,Dunkley ML,Moore R,Reynolds S,Bastin DA,Kyd JM,Cripps AW

更新日期：2000-09-15 00:00:00

abstract：:Plasmid DNA encoding herpes simplex virus type-1 glycoprotein D (gD-1) was complexed with asialoorosomucoid conjugated to poly-L-lysine. Following its intravenous injection into BALB/c mice, this complex was targeted to the liver. Liver cells expressing gD-1 were detected immunohistochemically through day 6 post-immun...

journal_title：Vaccine

authors： Rogers JV,Hull BE,Fink PS,Chiou HC,Bigley NJ

更新日期：2000-02-14 00:00:00

abstract：:A recombinant vaccine strain SL3261/pLT105 of attenuated aroA Salmonella enterica serovar Typhimurium SL3261 strain expressing a secreted dengue virus type 2 non-structural NS1 and Yersinia pestis F1 (Caf1) fusion protein, rNS1:Caf1, was generated. Immunological evaluation was performed by prime-boost vaccine regimen....

journal_title：Vaccine

authors： Liu WT,Lin WT,Tsai CC,Chuang CC,Liao CL,Lin HC,Hung YW,Huang SS,Liang CC,Hsu HL,Wang HJ,Liu YT

更新日期：2006-07-26 00:00:00

abstract：INTRODUCTION:Diarrhea is one of the leading causes of death in children under 5, and an estimated 39% of these deaths are attributable to rotavirus. Currently two live, oral rotavirus vaccines have been introduced on the market; however, the herd immunity effect associated with rotavirus vaccine has not yet been quanti...

journal_title：Vaccine

authors： Pollard SL,Malpica-Llanos T,Friberg IK,Fischer-Walker C,Ashraf S,Walker N

更新日期：2015-07-31 00:00:00

abstract：:We successfully re-vaccinated hepatitis B virus (HBV) vaccine non-responders using a double dose of the combined hepatitis A virus (HAV) and HBV vaccine. The hope was to improve priming of hepatitis B surface antigen (HBsAg)-specific cell mediated immune response (CMI) by an increased antigen dose and a theoretical ad...

journal_title：Vaccine

authors： Nyström J,Cardell K,Björnsdottir TB,Fryden A,Hultgren C,Sällberg M

更新日期：2008-11-05 00:00:00

abstract：:We have investigated immunological responses in BALB/c mice following transcutaneous (TC) delivery of fraction 1 (F1) and V subunits from Yersinia pestis in conjunction with an enterotoxin-derived adjuvant (cholera toxin, CT). It was found that two or more TC applications of F1 and V subunits (admixed with cholera tox...

journal_title：Vaccine

authors： Eyles JE,Elvin SJ,Westwood A,Lebutt CS,Alpar HO,Somavarapu S,Williamson ED

更新日期：2004-10-22 00:00:00

abstract：:The annual winter outbreak of influenza is one of the major cause of morbidity and mortality among frail elderly people. The aim of the present study was to identify prevalence and predictors of influenza vaccination in a large European population of frail and old people living in community. This was an observational ...

journal_title：Vaccine

authors： Landi F,Onder G,Carpenter I,Garms-Homolova V,Bernabei R

更新日期：2005-06-10 00:00:00

abstract：:Rabies is one of the most lethal infectious diseases in the world, with a mortality approaching 100%. There are between 60,000 and 70,000 reported annual deaths, but this is probably an underestimation. Despite the fact that there are vaccines available for rabies, there is a real need of developing more efficacious a...

journal_title：Vaccine

authors： Fontana D,Kratje R,Etcheverrigaray M,Prieto C

更新日期：2015-08-20 00:00:00