Levels of testosterone in the plasma, gonads, and adrenals during fetal development of the rabbit.

abstract：:The purpose of this study was to examine how the physical characteristics of light influence the short photoperiod-induced atrophy of the reproductive system. In the first experiment, groups of Syrian hamsters were exposed to a 14-h light, 10-h dark (14:10) photoperiod, a 11:13 photoperiod or a 11:13 photoperiod exten...

journal_title：Endocrinology

authors： Brainard GC,Vaughan MK,Reiter RJ

更新日期：1986-08-01 00:00:00

abstract：:The developmental appearance and regulation of hypothalamic vasopressin (prepropressophysin) mRNA was studied using quantitated in situ hybridization techniques. Vasopressin mRNA levels in the supraoptic nuclei were reliably detected on day 16 of gestation, while mRNA in the suprachiasmatic nuclei (SCN) was detectable...

journal_title：Endocrinology

authors： Reppert SM,Uhl GR

更新日期：1987-06-01 00:00:00

abstract：:Recent in vitro and in vivo evidence shows that secretion of parathyroid hormone (PTH) and calcitonin (CT) is stimulated by beta-adrenergic agonists and inhibited by beta-adrenergic antagonists. To assess the possible roles of adrenal medullary or adrenergic nerve terminal catecholamines in calcium homeostasis, we hav...

journal_title：Endocrinology

authors： Heath H 3rd

更新日期：1980-10-01 00:00:00

abstract：:Human decidual cells synthesize and release decidual PRL (dPRL) immunologically and biochemically identical to human pituitary PRL. However, stimulators and inhibitors of PRL secretion such as TRH, bromocriptine or dopamine have no effect on dPRL release. The evidence for the involvement of Ca2+ in dPRL release is bas...

journal_title：Endocrinology

authors： Sartor P,Couderc B,Corcuff JB,Odessa MF,Mayer G,Dufy B

更新日期：1992-06-01 00:00:00

abstract：:MCF-7 cells migrate through vitronectin-coated filters in response to insulin-like growth factor I (IGF-I); migration is inhibited by the matrix metalloproteinase (MMP) inhibitor BB-94, but not by the serine proteinase inhibitor aprotinin. MMP-9 was identified in the conditioned medium of MCF-7 cells; in addition, flu...

journal_title：Endocrinology

authors： Mira E,Mañes S,Lacalle RA,Márquez G,Martínez-A C

更新日期：1999-04-01 00:00:00

abstract：:Estrogen or raloxifene (LY156758) prevent estrogen deficiency-induced bone loss in animals and humans. We demonstrated in the rat that a 22% reduction in bone mineral density generated by ovariectomy was associated with a 2-fold reduction of transforming growth factor-beta 3 (TGF beta 3) messenger RNA expression in th...

journal_title：Endocrinology

authors： Yang NN,Bryant HU,Hardikar S,Sato M,Galvin RJ,Glasebrook AL,Termine JD

更新日期：1996-05-01 00:00:00

abstract：:Oxytocin (OT) is released by the posterior pituitary during male orgasm and is supposed to participate in the ejaculatory process. We now report evidence demonstrating the presence of an OT receptor gene (real-time RT-PCR and Northern blot) and protein (immunohistochemistry, Western blot, and binding studies) expressi...

journal_title：Endocrinology

authors： Vignozzi L,Filippi S,Luconi M,Morelli A,Mancina R,Marini M,Vannelli GB,Granchi S,Orlando C,Gelmini S,Ledda F,Forti G,Maggi M

更新日期：2004-04-01 00:00:00

abstract：:Sex difference in the number of neurons projecting axons from the lateral septum (LS) to the midbrain central gray (MCG) that are concerned with the lordosis-inhibiting system was investigated by injection of Fluoro-Gold (FG), a retrograde tracer, into the rostral MCG on the right side in male and female rats. Immunoh...

journal_title：Endocrinology

authors： Tsukahara S,Yamanouchi K

更新日期：2002-01-01 00:00:00

abstract：:Activins stimulate FSH synthesis and secretion by pituitary gonadotrope cells. Activin A induction of porcine and murine FSHβ (Fshb) gene transcription in immortalized gonadotropes is dependent on homolog of Drosophila mothers against decapentaplegic (SMAD) proteins as well as the forkhead transcription factor L2 (FOX...

journal_title：Endocrinology

authors： Lamba P,Wang Y,Tran S,Ouspenskaia T,Libasci V,Hébert TE,Miller GJ,Bernard DJ

更新日期：2010-11-01 00:00:00

abstract：:Maintenance of cell polarity is essential for Sertoli cell and blood-testis barrier (BTB) function and spermatogenesis; however, the signaling mechanisms that regulate the integrity of the cytoskeleton and polarity of Sertoli cells are not fully understood. Here, we demonstrate that rapamycin-insensitive component of ...

journal_title：Endocrinology

authors： Dong H,Chen Z,Wang C,Xiong Z,Zhao W,Jia C,Lin J,Lin Y,Yuan W,Zhao AZ,Bai X

更新日期：2015-11-01 00:00:00

abstract：:B-cell lymphoma 2 (BCL2) family kin (BFK) is a recently identified novel protein that is similar to proteins of the BCL2 family. In the present study, we discovered that the mouse Bfk transcript is expressed at the highest level in the epididymis. Two transcripts of 0.9 and 2.6 kb in size were identified, with alterna...

journal_title：Endocrinology

authors： Pujianto DA,Damdimopoulos AE,Sipilä P,Jalkanen J,Huhtaniemi I,Poutanen M

更新日期：2007-07-01 00:00:00

abstract：:In the ewe, photoperiod modulates LH and PRL secretion as well as median eminence (ME) dopaminergic activity. The studies reported here were designed to characterize the functional significance of this photoperiodic modulation of ME dopaminergic neuron activity in relation to the regulation of LH and PRL secretion. Th...

journal_title：Endocrinology

authors： Viguié C,Thibault J,Thiéry JC,Tillet Y,Malpaux B

更新日期：1997-01-01 00:00:00

abstract：:Properties of cyclic 3',5'-nucleotide phosphodiesterase in the 100,500 X g supernatant of the bovine thyroid were investigated. The enzyme activity was measured by a radioisotopic method using an anionic-exchange resin, and it was found that the activity was stimulated by Mg2+. Sephadex G-200 gel filtration separated ...

journal_title：Endocrinology

authors： Yagura T,Azuma Y,Akazawa Y,Nagata I,Uchino H

更新日期：1978-11-01 00:00:00

abstract：:The objectives of this study were to investigate the presence of immunoreactive GnRH (irGnRH) in scleractinian coral, Euphyllia ancora, study its seasonal variation, and evaluate its biological activity. irGnRH was detected and quantified in coral polyps. The biological activity of coral irGnRH was tested on pituitary...

journal_title：Endocrinology

authors： Twan WH,Hwang JS,Lee YH,Jeng SR,Yueh WS,Tung YH,Wu HF,Dufour S,Chang CF

更新日期：2006-01-01 00:00:00

abstract：:Excessive accumulation of body fat triggers insulin resistance and features of the metabolic syndrome. Recently, evidence has accumulated that obesity, type 2 diabetes, and metabolic syndrome are associated with reduced levels of serum prolactin (PRL) in humans and rodents, raising the question of whether low PRL leve...

journal_title：Endocrinology

authors： Ruiz-Herrera X,de Los Ríos EA,Díaz JM,Lerma-Alvarado RM,Martínez de la Escalera L,López-Barrera F,Lemini M,Arnold E,Martínez de la Escalera G,Clapp C,Macotela Y

更新日期：2017-01-01 00:00:00

abstract：:Mature 31- and 34-kDa inhibin A and B negatively regulate the release of FSH from the anterior pituitary; however, a direct comparison of these hormones in vivo has not been undertaken. The bioactivities of highly purified preparations of recombinant human 31-kDa inhibin A and B were determined in rat pituitary cells ...

journal_title：Endocrinology

authors： Makanji Y,Temple-Smith PD,Walton KL,Harrison CA,Robertson DM

更新日期：2009-10-01 00:00:00

abstract：:FSH stimulates follicular growth through inducing granulosa cell proliferation. Our working hypothesis is that mitogenesis is facilitated by a locally produced growth/differentiation factor(s) that modulates FSH action in developing granulosa cells. The present study was undertaken to examine the effect of the related...

journal_title：Endocrinology

authors： Miró F,Hillier SG

更新日期：1996-02-01 00:00:00

abstract：:The effects of secretagogue(s) from mouse decidual tissue on the release of mouse placental lactogen-II (mPL-II) were studied. Decidual tissue was obtained from 10- and 11-day-pregnant mice. The tissue was homogenized, extracted, and the tissue extract was made 50% saturated with ammonium sulfate. Both the precipitate...

journal_title：Endocrinology

authors： Thordarson G,Southard JN,Talamantes F

更新日期：1991-09-01 00:00:00

abstract：:The possibility of direct pituitary effects of sex steroids on gonadotropin gene expression and synthesis was studied in male rats. The animals were treated with a potent GnRH antagonist, Ac-D-pClPhe-D-pClPhe-D-Trp-Ser-Tyr-D-Arg-Leu-Arg-Pro-D-Ala-+ ++NH2CH3COOH (Org 30276; 0.5 mg/kg BW, sc, twice daily) for 10 days. G...

journal_title：Endocrinology

authors： Perheentupa A,Huhtaniemi I

更新日期：1990-06-01 00:00:00

abstract：:Cell proliferation, terminal differentiation, and angiogenesis occur during cycles of follicular and luteal development. In other paradigms, mac25, a potent tumor inhibitor is strongly induced in senescent epithelial cells, whereas CTGF stimulates angiogenesis and wound healing. Using in situ hybridization and immunoh...

journal_title：Endocrinology

authors： Wandji SA,Gadsby JE,Barber JA,Hammond JM

更新日期：2000-07-01 00:00:00

abstract：:FSH has been shown to stimulate the uptake of calcium in cultured rat Sertoli cells, resulting in an increase in cytosolic calcium concentrations. One possibility which has been put forth is that the FSH receptor per se may act as a calcium channel. This is all the more tantalizing given the proposed structure of this...

journal_title：Endocrinology

authors： Shibata EF,Matsuda JJ,Volk KA,Collison KA,Segaloff DL

更新日期：1992-08-01 00:00:00

abstract：:In adult male rhesus monkeys, 1 day of fasting leads to a profound suppression of LH secretion that is rapidly reversed with refeeding. To test the hypothesis that changes in insulin secretion during fasting and refeeding mediate the changes in LH secretion, blood samples for LH measurement were obtained between 0900-...

journal_title：Endocrinology

authors： Williams NI,Lancas MJ,Cameron JL

更新日期：1996-06-01 00:00:00

abstract：:Embryo implantation is a highly synchronized event between an activated blastocyst and a receptive endometrium. The success of this process relies on the dynamic interplay of estrogen (E(2)) and progesterone (P(4)), however, the details of this interaction are not entirely clear. Recent data implicate E(2) and P(4) in...

journal_title：Endocrinology

authors： Frolova A,Flessner L,Chi M,Kim ST,Foyouzi-Yousefi N,Moley KH

更新日期：2009-03-01 00:00:00

abstract：:Fibroblast growth factor (FGF) 21, a unique, largely liver-derived endocrine member of the FGF superfamily, is often thought of as a fasting factor owing to its induction in rodents during starvation. However, FGF21 is not increased by fasting for periods of <7 days in humans; instead, it rises sharply after acute alc...

journal_title：Endocrinology

authors： Gillum MP

更新日期：2018-05-01 00:00:00

abstract：:This study was performed to test the hypothesis that reflex increases in heart rate, PRA, and plasma concentrations of vasopressin, angiotensin-II, ACTH, and cortisol are reduced during pregnancy. The hypothesis was tested by measuring, in pregnant and nonpregnant conscious dogs, changes in arterial and atrial pressur...

journal_title：Endocrinology

authors： Brooks VL,Keil LC

更新日期：1994-11-01 00:00:00

abstract：:Amplification of insulin secretion by cAMP is mediated by protein kinase A (PKA) and exchange protein directly activated by cAMP (Epac). Using selective activators, we determined how each effector influences the cytosolic free Ca(2+) concentration ([Ca(2+)]c) and insulin secretion in mouse islets. Alone PKA activator ...

journal_title：Endocrinology

authors： Henquin JC,Nenquin M

更新日期：2014-09-01 00:00:00

abstract：:Male and female Holtzman rats were raised from weaning on a vitamin D-deficient diet (-D). Control (+D) animals were raised on the same diet and orally given 70 IU vitamin D3 twice each week. Serum Ca levels fell at the same rate in -D males and females. In contrast, serum parathyroid hormone increased more rapidly in...

journal_title：Endocrinology

authors： Thomas ML,Forte LR

更新日期：1981-11-01 00:00:00

abstract：:Intravenous (i.v.) administration of TRF (1 mg/kg) increases the LD50 of pentobarbital (PB) by 25% while the same dose of somatostatin results in a 30% reduction in PB LD50. A similar increase of PB LD50 by TRF was observed in hypophysectomized rats. Mortality was completely abolished in rats receiving TRF (1 mg/kg) t...

journal_title：Endocrinology

authors： Brown M,Vale W

更新日期：1975-05-01 00:00:00

abstract：:The alphaVbeta3 integrin is an important determinant of IGF-I-stimulated receptor phosphorylation and biological actions. Blocking ligand occupancy of alphaVbeta3 with the distintegrin echistatin reduces IGF-I-stimulated receptor phosphorylation, and it inhibits cellular migration and DNA synthesis responses to IGF-I....

journal_title：Endocrinology

authors： Maile LA,Clemmons DR

更新日期：2002-11-01 00:00:00

abstract：:We used differential display PCR on two GnRH producing cell lines to identify genes involved in GnRH gene expression and neuronal migration. RNA from Gn10 cells (derived from a tumor in the olfactory area when GnRH neurons are migrating and make low levels of GnRH) and from GT1-7 cells (derived from a tumor in forebra...

journal_title：Endocrinology

authors： Fang Z,Xiong X,James A,Gordon DF,Wierman ME

更新日期：1998-08-01 00:00:00