Effect of light irradiance and wavelength on the Syrian hamster reproductive system.

abstract：:In vivo and in vitro evidence indicates that FSH is a primary regulator of testicular inhibin production. However, recent reports suggest that LH may also promote inhibin secretion in vivo. To investigate whether LH regulates inhibin subunit messenger RNA (mRNA) expression as well, we examined the effects of hypophyse...

journal_title：Endocrinology

authors： Krummen LA,Morelos BS,Bhasin S

更新日期：1990-09-01 00:00:00

abstract：:The nature and role of the peptidergic innervation of the ovary were examined by determining the location and function of vasoactive intestinal peptide (VIP)-containing nerve fibers in the immature rat ovary. Immunohistofluorescence analysis of prepubertal ovaries using a specific VIP antibody revealed sparse delicate...

journal_title：Endocrinology

authors： Ahmed CE,Dees WL,Ojeda SR

更新日期：1986-04-01 00:00:00

abstract：:Mice with the recessively inherited obese-hyperglycemic syndrome (ob/ob) and their nonobese litter mates were studied over a 26-week period. The body weights and serum glucose levels of ob/ob mice began to rise markedly at 5-6 weeks of age and remained elevated throughout the period of study. Obese mice were significa...

journal_title：Endocrinology

authors： Larson BA,Sinha YN,Vanderlaan WP

更新日期：1976-01-01 00:00:00

abstract：:Inflammation can interfere with endometrial receptivity. We examined how interleukin 1β (IL-1β) affects expression of the uterine gap junction protein connexin 43 (Cx43), which is known to be critical for embryonic implantation. We used an in vitro model of human endometrial stromal cells (ESCs), Western blotting, and...

journal_title：Endocrinology

authors： Yu J,Berga SL,Zou W,Yook DG,Pan JC,Andrade AA,Zhao L,Sidell N,Bagchi IC,Bagchi MK,Taylor RN

更新日期：2017-12-01 00:00:00

abstract：:After hormonal ablation, 90% of the secretory epithelial cells of the prostate undergo apoptosis, and the remaining cells are reorganized as the tissue is remodeled. Using differential display RT-PCR of total RNA extracted from the rat ventral prostate before and 4 days after castration, we have cloned and sequenced a...

journal_title：Endocrinology

authors： Morrissey C,Bennett S,Nitsche E,Guenette RS,Wong P,Tenniswood M

更新日期：1999-07-01 00:00:00

abstract：:The nuclear orphan receptor human estrogen receptor-related receptor (ERR)-alpha is implicated in bone metabolism. We studied the effect of ERRalpha silencing in human mesenchymal stem cells (hMSCs) during osteoblastogenesis. We found that ERRalpha silencing led to an increase of bone sialoprotein and a decrease of os...

journal_title：Endocrinology

authors： Delhon I,Gutzwiller S,Morvan F,Rangwala S,Wyder L,Evans G,Studer A,Kneissel M,Fournier B

更新日期：2009-10-01 00:00:00

abstract：:In songbirds, singing behavior is controlled by a discrete network of interconnected brain nuclei known collectively as the song control system. Both the development of this system and the expression of singing behavior in adulthood are strongly influenced by sex steroid hormones. Although both androgenic and estrogen...

journal_title：Endocrinology

authors： Bernard DJ,Bentley GE,Balthazart J,Turek FW,Ball GF

更新日期：1999-10-01 00:00:00

abstract：:Changes in serum and pituitary LH and FSH concentrations have been measured in the newborn male rat before, during, and up to 24 h after birth. A sudden and transient increase of serum and pituitary gonadotropins is observed at birth, which is followed by a rapid increase of absolute and relative testicular weights be...

journal_title：Endocrinology

authors： Corbier P,Kerdelhue B,Picon R,Roffi J

更新日期：1978-12-01 00:00:00

abstract：:Magnocellular hypothalamic neurons in the rat supraoptic nucleus (SON) normally produce either vasopressin (VP) or oxytocin (OT). Here we demonstrate that many magnocellular neurons in the SON of lactating rats synthesize both hormones at the same time. We show the colocalization of the messenger (m) RNA that encodes ...

journal_title：Endocrinology

authors： Mezey E,Kiss JZ

更新日期：1991-10-01 00:00:00

abstract：:We have studied potential mechanisms by which zinc deficiency (ZD) may result in growth impairment in young animals. Dietary-induced ZD in young rats resulted in diminished skeletal growth as measured by tibial epiphyseal width. Treatment with bovine GH (bGH) did not increase skeletal growth suggesting GH resistance r...

journal_title：Endocrinology

authors： Oner G,Bhaumick B,Bala RM

更新日期：1984-05-01 00:00:00

abstract：:We have previously demonstrated in vitro that 1alpha,25-dihydroxyvitamin D3 (calcitriol) treatment increases p27 expression and decreases cell proliferation in cultured thyroid carcinoma cell lines. We hypothesized that in vivo treatment with calcitriol would have a beneficial effect on thyroid carcinoma growth and pr...

journal_title：Endocrinology

authors： Dackiw AP,Ezzat S,Huang P,Liu W,Asa SL

更新日期：2004-12-01 00:00:00

abstract：:Dopamine D2 receptor agonists are commonly used in the control of PRL-secreting adenomas, and the sensitivity of dopamine agonists during long term therapy is exquisite. However, the molecular mechanisms responsible for the maintenance of this cellular sensitivity to dopamine agonists remain poorly understood. In the ...

journal_title：Endocrinology

authors： Ng GY,Varghese G,Chung HT,Trogadis J,Seeman P,O'Dowd BF,George SR

更新日期：1997-10-01 00:00:00

abstract：:We studied the estrogen-dependent expression of epidermal growth factor (EGF), transforming growth factor (TGF) alpha, and EGF receptor gene transcripts in human fallopian tubes in vivo and in vitro. Competitive polymerase chain reaction (PCR) was performed on the fallopian tube RNA samples from the postmenopausal wom...

journal_title：Endocrinology

authors： Adachi K,Kurachi H,Homma H,Adachi H,Imai T,Sakata M,Higashiguchi O,Yamaguchi M,Morishige K,Sakoyama Y

更新日期：1995-05-01 00:00:00

abstract：:[125I]-[D-Ser(TBU)6]LHRH-EA binds to a single class of high affinity sites in rat anterior pituitary cells in culture at an apparent dissociation constant of 0.25 nM at 0-4C. The order of potency of a representative group of LHRH agonists and antagonists to displace the labeled ligand is similar to their LH-releasing ...

journal_title：Endocrinology

authors： Giguere V,Lefebvre FA,Labrie F

更新日期：1981-01-01 00:00:00

abstract：:A novel NADPH-dependent cytosolic 3,5,3'-triiodo-L-thyronine (T3)-binding protein (CTBP) was purified by sequential fractionation of rat liver cytosol on Q-Sepharose, phenyl-Sepharose, red-Sepharose, and polyacrylamide gel electrophoresis under nondenaturing conditions. The CTBP had a sedimentation coefficient of 5.1S...

journal_title：Endocrinology

authors： Kobayashi M,Hashizume K,Suzuki S,Ichikawa K,Takeda T

更新日期：1991-10-01 00:00:00

abstract：:Apolipoprotein-E (apoE) has been shown by noncovalent binding and photoaffinity labeling with [125I]T4 to possess a single L-T4 binding site with a K5 of about 3 x 10(7) M-1 and a relative affinity for analogs of L-T4 = D-T4 = rT3 = triiodothyroacetic acid > L-T3. T4 binding was not affected by the flavonoid EMD 21388...

journal_title：Endocrinology

authors： Benvenga S,Cahnmann HJ,Robbins J

更新日期：1993-09-01 00:00:00

abstract：:The antigenic epitopes of human GH (hGH) have been investigated using monoclonal antibodies (Mabs) to hGH. A panel of 12 Mabs was incorporated into two-site binding assays in order to investigate the antigenic surface of hGH. Nine reaction patterns were observed. The Mabs were further characterized in terms of their c...

journal_title：Endocrinology

authors： Strasburger CJ,Kostyo J,Vogel T,Barnard GJ,Kohen F

更新日期：1989-03-01 00:00:00

abstract：:QRFP, an RFamide peptide, was recently identified as an endogenous ligand of an orphan G protein-coupled receptor, GPR103. Recent investigation revealed that acute intracerebroventricular (ICV) administration of QRFP26/P518/26RFa, a constitutive part of QRFP43 (43-amino acid-residue form of QRFP), increases appetite i...

journal_title：Endocrinology

authors： Moriya R,Sano H,Umeda T,Ito M,Takahashi Y,Matsuda M,Ishihara A,Kanatani A,Iwaasa H

更新日期：2006-06-01 00:00:00

abstract：:The adrenergic control of cAMP and 3',5'-cyclic GMP (cGMP) in dispersed adult rat pinealocytes was investigated. Norepinephrine treatment increased cAMP and cGMP content 60- and 400-fold, respectively; both alpha- and beta-adrenoceptors had to be activated for these responses to occur. Beta-Adrenergic stimulation alon...

journal_title：Endocrinology

authors： Vanecek J,Sugden D,Weller J,Klein DC

更新日期：1985-06-01 00:00:00

abstract：:Myocardial fibrosis is a key pathological change in a variety of heart diseases contributing to the development of heart failure, arrhythmias, and sudden death. Recent studies have shown that relaxin prevents and reverses cardiac fibrosis. Endogenous expression of relaxin was elevated in the setting of heart disease; ...

journal_title：Endocrinology

authors： Gu HP,Lin S,Xu M,Yu HY,Du XJ,Zhang YY,Yuan G,Gao W

更新日期：2012-08-01 00:00:00

abstract：:Endotoxin has been shown to stimulate GH secretion in human and sheep. However, changes in hypothalamic neurohormones involved in the GH regulation by endotoxin have never been studied in vivo. In sheep it is possible to collect hypophysial portal blood (HPB) and quantify GH-releasing hormone (GHRH) and somatostatin (...

journal_title：Endocrinology

authors： Briard N,Guillaume V,Frachebois C,Rico-Gomez M,Sauze N,Oliver C,Dutour A

更新日期：1998-06-01 00:00:00

abstract：:Ovarian angiotensin I (Ang I)-converting enzyme (ACE), estimated by the specific binding of the ACE inhibitor [125I]iodo-MK-351A, is localized on multiple ovarian structures, including follicular granulosa cells, corpora lutea, terminal epithelium, and ovarian blood vessels, but total ovarian ACE does not display a cy...

journal_title：Endocrinology

authors： Daud AI,Bumpus FM,Husain A

更新日期：1990-06-01 00:00:00

abstract：:The Djungarian hamster displays photoperiodic variations in gonadal size synchronized to the seasons by the nightly secretion of the pineal hormone melatonin. In short photoperiod (SP), the gonads regress in size, and circulating sex steroids levels decline. Thus, the brain is subject to seasonal variations of both me...

journal_title：Endocrinology

authors： Bolborea M,Laran-Chich MP,Rasri K,Hildebrandt H,Govitrapong P,Simonneaux V,Pévet P,Steinlechner S,Klosen P

更新日期：2011-10-01 00:00:00

abstract：:Pancreatic beta-cells and HIT-T15 cells exhibit oscillations of cytosolic calcium ([Ca2+]i) that are dependent on glucose metabolism and appear to trigger pulsatile insulin secretion. Significantly, differences in the pattern of this [Ca2+]i oscillatory activity may have important implications for our understanding of...

journal_title：Endocrinology

authors： Leech CA,Holz GG 4th,Habener JF

更新日期：1994-07-01 00:00:00

abstract：:A presumptive mitochondrial T3 receptor previously reported from this and other laboratories appears capable of accounting for the activation of liver mitochondrial oxidative phosphorylation within 30 min after iv bolus injection of nanogram doses of T3 into hypothyroid rats. The inner mitochondrial membrane carrier a...

journal_title：Endocrinology

authors： Sterling K

更新日期：1986-07-01 00:00:00

abstract：:A basic somatomedin preparation results in a 2-fold stimulation of incorporation of both [3H]leucine into protein and 35SO4 into glycosaminoglycans by cultured chick sternal chondrocytes. The stimulation is seen in the presence of 20 mM 4-methylumbelliferyl-beta-D-xyloside alone but is not observable in the presence o...

journal_title：Endocrinology

authors： Kemp SF,Hintz RL

更新日期：1980-03-01 00:00:00

abstract：:To investigate GH's role in diabetic end organ damage, experimental diabetes was induced with streptozotocin (STZ) in bovine GH (bGH) or bGH antagonist transgenic mice and in their nontransgenic (NTG) litter mates. Body growth, blood glucose, serum insulin-like growth factor-I levels, liver GH receptor (GHR) binding, ...

journal_title：Endocrinology

authors： Chen NY,Chen WY,Bellush L,Yang CW,Striker LJ,Striker GE,Kopchick JJ

更新日期：1995-02-01 00:00:00

abstract：:NADPH-cytochrome P-450 reductase (EC 1.6.2.4), the enzyme involved in progesterone 17-hydroxylation, was purified to apparent homogeneity by detergent solubilization of the microsomal fractions of liver and testis from untreated rats. The enzymes from these two tissues were then compared with regard to several paramet...

journal_title：Endocrinology

authors： Hales DB,Betz G

更新日期：1986-08-01 00:00:00

abstract：:The effect of fibroblast growth factor (FGF) on LH-stimulated testosterone production was investigated using primary cultures of rat testicular cells. Testicular cells obtained from neonatal rats (8-9 days of age) were maintained in culture for 3 days and then challenged with LH with or without basic FGF. After 3 addi...

journal_title：Endocrinology

authors： Fauser BC,Baird A,Hsueh AJ

更新日期：1988-12-01 00:00:00

abstract：:Enhanced epinephrine secretion from adrenal chromaffin cells (ACCs) is an important homeostatic response to severe systemic inflammation during sepsis. Evidence suggests that increased activation of ACCs by preganglionic sympathetic neurons and direct alterations in ACC function contribute to this response. However, t...

journal_title：Endocrinology

authors： Lukewich MK,Lomax AE

更新日期：2014-01-01 00:00:00