Modulation of the acoustic startle reflex by infusion of corticotropin-releasing hormone into the nucleus reticularis pontis caudalis.

abstract：:Long-term potentiation (LTP) has a memory-like consolidation period during which it becomes progressively stabilized. However, it is unknown how the consolidation is achieved. The present study demonstrates that nicotine reverses stabilized LTP in the hippocampal CA1 region, providing the first evidence that consolida...

journal_title：Brain research

authors： Guan X,Nakauchi S,Sumikawa K

更新日期：2006-03-17 00:00:00

abstract：:Infusion of 1 microgram of carbachol, a potent cholinergic agonist, into the lateral septum of the urethane-anaesthetized rat systematically caused the induction of clear-cut hippocampal theta (theta). However, infusion of an equivalent amount of the drug into the hippocampus, close to the recording electrode, failed ...

journal_title：Brain research

authors： Monmaur P,Ayadi K,Breton P

更新日期：1993-12-24 00:00:00

abstract：:The sexually dimorphic nucleus of the preoptic area (SDN-POA) is the most striking structure displaying a morphological sex difference in the rat brain. A potentially homologous nucleus has been identified in the human hypothalamus. The objective of the present study was to pursue the putative homology of the rat and ...

journal_title：Brain research

authors： Gao B,Moore RY

更新日期：1996-12-02 00:00:00

abstract：:Stanniocalcin (STC-1), a 50 kDa glycoprotein hormone that regulates calcium/phosphate homeostasis in bony fish and mammals, has been shown to be expressed in central neurons and choroid plexus, and to exert a protective effect against hypercalcemic and hypoxic damage to neurons. Circumventricular organs are known to f...

journal_title：Brain research

authors： Ratkovic S,Wagner GF,Ciriello J

更新日期：2008-07-07 00:00:00

abstract：:The motivational effects of exclusively peripheral or central opiate receptor blockade were studied using place conditioning. Place aversions were observed with intraventricular (i.c.v.) methylnaloxone (MN) in both naive (200-1000 ng) and morphine-dependent rats (50-500 ng). Subcutaneous MN (0.03-10 mg/kg) was ineffec...

journal_title：Brain research

authors： Hand TH,Koob GF,Stinus L,Le Moal M

更新日期：1988-12-06 00:00:00

abstract：:Intracerebroventricular microinjection of thyrotropin-releasing hormone (TRH) potently blocked the development of, as well as promptly reversed, epinephrine-stimulated hyperglycemia in mice. The central antihyperglycemic effect was dose-related (0.1-10 micrograms), could be reproduced by an intravenous injection of a ...

journal_title：Brain research

authors： Amir S,Harel M,Rivkind AI

更新日期：1987-12-01 00:00:00

abstract：:Behavioral stress is likely to contribute to the development of hypertension in susceptible individuals. We reported that hemodynamic response patterns to acute startle vary and that those patterns predict the predisposition of rats to sustained stress-induced elevations in arterial pressure. Since considerable eviden...

journal_title：Brain research

authors： Tan Y,Gan Q,Knuepfer MM

更新日期：2003-04-04 00:00:00

abstract：:The present study aimed to determine the kinetics of L-3, 4-dihydroxyphenylalanine (L-DOPA) uptake in an immortalised cell line of rat capillary cerebral endothelial cells (clones RBE 4 and RBE 4B), to define the type of inhibition produced by L-5-hydroxytryptophan (L-5-HTP), 2-aminobicyclo(2,2,1)-heptane-2-carboxylic...

journal_title：Brain research

authors： Gomes P,Soares-da-Silva P

更新日期：1999-05-22 00:00:00

abstract：:The aim of this study was to investigate the relationship between serum metabolomic biomarkers and brain in vivo magnetic resonance spectroscopy (MRS) biomarkers in patients with Parkinson's disease (PD) as well as to investigate compound concentration changes by comparing the results with healthy control subjects. Un...

journal_title：Brain research

authors： Toczylowska B,Zieminska E,Michałowska M,Chalimoniuk M,Fiszer U

更新日期：2020-12-01 00:00:00

abstract：:To determine if cell death participates in the regulation of cell number between interconnecting populations of the neocortex, we sectioned the corpus callosum of neonatal hamsters, thus depriving callosally projecting cells of their normal targets and callosally-recipient cells of their normal afference. The numbers ...

journal_title：Brain research

authors： Windrem MS,Jan de Beur S,Finlay BL

更新日期：1988-09-01 00:00:00

abstract：:The content of arginine vasopressin and oxytocin in various extrahypothalamic sites of the rat brain and spinal cord was determined by specific radioimmunoassays after lesions had been made in either the paraventricular (PVN), supraoptic (SON) or suprachiasmatic nuclei (SCN). In some animals all 3 nuclei were destroye...

journal_title：Brain research

authors： Hawthorn J,Ang VT,Jenkins JS

更新日期：1985-10-28 00:00:00

abstract：:The mesencephalic reticular formation (MRF) of cats anesthetized with N2O was stimulated electrically, and the effects of this stimulation on activity in the striate cortex were studied. The variations of intra- and extracellularly recorded unit activity and the changes in the extracellular potassium concentration wer...

journal_title：Brain research

authors： Singer W,Tretter F,Cynader M

更新日期：1976-01-30 00:00:00

abstract：:In rats with unilateral 6-hydroxydopamine lesions of the substantia nigra, a specific D1 dopamine receptor agonist, SKF 38393A, at a dose that does not itself produce turning, significantly increased the contralateral rotation observed following a low dose of the specific D2 agonist LY 171555. Doses of SKF 38393A or t...

journal_title：Brain research

authors： Robertson GS,Robertson HA

更新日期：1986-10-08 00:00:00

abstract：:The location and nature of the changes underlying long-term potentiation (LTP) remain controversial issues. In this study, we tested the possibility that changes in binding properties of the alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionate (AMPA/quisqualate and N-methyl-D-aspartate (NMDA) subtype of glutamate rec...

journal_title：Brain research

authors： Tocco G,Maren S,Shors TJ,Baudry M,Thompson RF

更新日期：1992-02-28 00:00:00

abstract：:There is a strong link between cognitive impairment and depression, but up to date it is not clear whether cognitive impairment is 'cause' or 'consequence' of depression. Therefore, we here examined the effect of cognitive impairment induced by permanent occlusion of common carotid arteries, a model known as two-vesse...

journal_title：Brain research

authors： Khojasteh F,Nahavandi A,Mehrpouya S,Homberg JR,Mirzamohammadi S,Raufi S,Soleimani M,Barati M

更新日期：2015-01-30 00:00:00

abstract：:Amyloid deposition, a histopathological feature of Alzheimer's disease brain, may be the underlying cause of this disease. The isolation of enzymes involved in both the normal and aberrant or alternative processing of the beta-amyloid precursor protein may lead to an understanding of how beta-protein, the major compon...

journal_title：Brain research

authors： Razzaboni BL,Papastoitsis G,Koo EH,Abraham CR

更新日期：1992-09-04 00:00:00

abstract：:38 primary afferents originating from de-efferented cat tibialis anterior muscle spindles were investigated. Ramp-and-hold stretches of the host muscle were performed with a varying amount of muscle pre-stretch while recording the primary afferent discharges. From the discharge responses an interspike interval functio...

journal_title：Brain research

authors： Awiszus F,Schäfer SS

更新日期：1993-05-28 00:00:00

abstract：:Astrocytes associated with beta-amyloid (Aβ)-deposited senile plaques are a common neuropathological feature of Alzheimer's disease (AD). There is little doubt that the association of Aβ with the major component in the central nervous system cells significantly influences disease progression, however, the molecular me...

journal_title：Brain research

authors： Satoh K,Akatsu H,Yamamoto T,Kosaka K,Yokota H,Yamada T

更新日期：2012-03-02 00:00:00

abstract：:Brain protein kinase B (Akt) and glycogen synthase kinase-3 (GSK-3) activities are adaptable to changes of peripheral blood glucose level in vivo. GSK-3 phosphorylates microtube-associated protein tau at multiple sites, which can be antagonized by protein phosphatase-2A (PP-2A). The imbalance among these enzymes might...

journal_title：Brain research

authors： Qu Z,Jiao Z,Sun X,Zhao Y,Ren J,Xu G

更新日期：2011-04-06 00:00:00

abstract：:Thermoregulation is a complex intercommunicative function requiring coordination between core body temperature (CBT), the central nervous system, and peripheral vasculature. In menopausal women, dysregulation of thermoregulatory mechanisms leads to hot flushes and night sweats. A previous study in ovariectomized (OVX)...

journal_title：Brain research

authors： Pawlyk AC,Cosmi S,Alfinito PD,Maswood N,Deecher DC

更新日期：2006-12-06 00:00:00

abstract：:Metabolic dysfunction in the relay nuclei of the rat vibrissa circuit follows traumatic brain injury (TBI). This study examined the effects of mild (1.4-1.5 atm) parasagittal fluid-percussion injury on the electrophysiology of this circuit. TBI caused significant reductions in slope and increases in latency of vibriss...

journal_title：Brain research

authors： Sanders MJ,Dietrich WD,Green EJ

更新日期：2001-06-15 00:00:00

abstract：:Plectin is associated with intermediate filaments, such as glial fibrillary acidic protein (GFAP) and vimentin, which have an important role in the glial reactions after lesions. The present study investigates the plectin immunoreactivity following stab wounds in the cortex and the underlying white matter of adult rat...

journal_title：Brain research

authors： Kálmán M,Szabó A

更新日期：2000-02-28 00:00:00

abstract：:The nonsteroidal anti-inflammatory drugs are presumed to produce their analgesic effects by inhibiting the cyclooxygenase catalyzed metabolism of arachidonic acid to hyperalgesic prostanoids. This study examined the hyperalgesic effect of a range of prostaglandins. We found, employing the rat paw-withdrawal test, that...

journal_title：Brain research

authors： Taiwo YO,Levine JD

更新日期：1990-12-24 00:00:00

abstract：:Sprague-Dawley rats were submitted to bilateral ventral hippocampus lesions 7 days after birth according to the Lipska and Weinberger's procedure for modeling schizophrenia. The aim of the present work was to better characterize their learning capacity. A double latent inhibition study was conducted using respectively...

journal_title：Brain research

authors： Angst MJ,Macedo CE,Guiberteau T,Sandner G

更新日期：2007-04-27 00:00:00

abstract：:Previous studies showed that hyperbaric oxygen (HBO) promoted cell proliferation in hypoxic-ischemic (HI) neonate rats. Neural stem cells (NSC) existed in the brain lifelong and can be activated. This study was undertaken to assess whether HBO treatment promoted the proliferation of NSC and repaired the brain damage r...

journal_title：Brain research

authors： Wang XL,Zhao YS,Yang YJ,Xie M,Yu XH

更新日期：2008-07-30 00:00:00

abstract：:Tacrolimus (FK506), a potent immunosuppressive drug, is effective in attenuating brain infarction after cerebral ischemia. However, there has been no report characterizing the neuroprotective action and therapeutic time window of tacrolimus systematically using different types of stroke models and extended observation...

journal_title：Brain research

authors： Furuichi Y,Katsuta K,Maeda M,Ueyama N,Moriguchi A,Matsuoka N,Goto T,Yanagihara T

更新日期：2003-03-07 00:00:00

abstract：:We have examined the question of whether alpha-tubulin is detyrosylated during axonal transport in retinal ganglion cell axons and axons of spinal motor neurons. The degree of tyrosylation of alpha-tubulin was estimated from immunocytochemistry and immunoblotting with two anti-alpha-tubulin monoclonals, one of which (...

journal_title：Brain research

authors： Burgoyne RD,Norman KM

更新日期：1986-08-27 00:00:00

abstract：:Recent research suggests that in addition to its prominent role in appetitive learning, the nucleus accumbens (NAC) may also be involved in fear conditioning. In the present study, we investigated whether temporary inactivation of the NAC, by injection of tetrodotoxin (TTX), affects acquisition and expression of condi...

journal_title：Brain research

authors： Schwienbacher I,Fendt M,Richardson R,Schnitzler HU

更新日期：2004-11-19 00:00:00

abstract：:In order to establish the basic connectivity of physiologically identified somatosensory regions of the thalamus and telencephalon in the pigeon, injections of wheatgerm agglutinin-horseradish peroxidase were made under electrophysiological control and the projections were charted following conventional neurohistochem...

journal_title：Brain research

authors： Wild JM

更新日期：1987-06-02 00:00:00

abstract：:The default mode network (DMN) is characterised by coherent very low frequency (VLF) neural oscillations in the resting brain. The attenuation of this activity has been demonstrated following the transition from rest to performance of a broad range of cognitive goal-directed tasks. Whether the activity of resting stat...

journal_title：Brain research

authors： Hsu CF,Broyd SJ,Helps SK,Benikos N,Sonuga-Barke EJ

更新日期：2013-08-02 00:00:00